المؤلفون: Cécile Exertier, Alessandra Salerno, Lorenzo Antonelli, Annarita Fiorillo, Riccardo Ocello, Francesca Seghetti, Jessica Caciolla, Elisa Uliassi, Matteo Masetti, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Andrea Ilari, Maria Laura Bolognesi

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, medicinal chemistry campaign, drug discovery approaches, trypanosoma brucei <, leishmania infantum <, ex vivo <, based drug discovery, 9 , 14 , 10 , tr binding site, leishmaniasis trypanothione reductase, vitro <, silico <, k <, , tr inhibition, suitable target, still challenging, potent inhibitors, improve selectivity, difficult target

Relation: https://figshare.com/articles/journal_contribution/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925492

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01439.s001
https://figshare.com/articles/journal_contribution/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925492

المؤلفون: Cécile Exertier, Alessandra Salerno, Lorenzo Antonelli, Annarita Fiorillo, Riccardo Ocello, Francesca Seghetti, Jessica Caciolla, Elisa Uliassi, Matteo Masetti, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Andrea Ilari, Maria Laura Bolognesi

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, medicinal chemistry campaign, drug discovery approaches, trypanosoma brucei <, leishmania infantum <, ex vivo <, based drug discovery, 9 , 14 , 10 , tr binding site, leishmaniasis trypanothione reductase, vitro <, silico <, k <, , tr inhibition, suitable target, still challenging, potent inhibitors, improve selectivity, difficult target

Relation: https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925495

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01439.s002
https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925495

المؤلفون: Cécile Exertier, Alessandra Salerno, Lorenzo Antonelli, Annarita Fiorillo, Riccardo Ocello, Francesca Seghetti, Jessica Caciolla, Elisa Uliassi, Matteo Masetti, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Andrea Ilari, Maria Laura Bolognesi

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, medicinal chemistry campaign, drug discovery approaches, trypanosoma brucei <, leishmania infantum <, ex vivo <, based drug discovery, 9 , 14 , 10 , tr binding site, leishmaniasis trypanothione reductase, vitro <, silico <, k <, , tr inhibition, suitable target, still challenging, potent inhibitors, improve selectivity, difficult target

Relation: https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925501

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01439.s004
https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925501

المؤلفون: Cécile Exertier, Alessandra Salerno, Lorenzo Antonelli, Annarita Fiorillo, Riccardo Ocello, Francesca Seghetti, Jessica Caciolla, Elisa Uliassi, Matteo Masetti, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Andrea Ilari, Maria Laura Bolognesi

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, medicinal chemistry campaign, drug discovery approaches, trypanosoma brucei <, leishmania infantum <, ex vivo <, based drug discovery, 9 , 14 , 10 , tr binding site, leishmaniasis trypanothione reductase, vitro <, silico <, k <, , tr inhibition, suitable target, still challenging, potent inhibitors, improve selectivity, difficult target

Relation: https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925510

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01439.s007
https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925510

المؤلفون: Cécile Exertier, Alessandra Salerno, Lorenzo Antonelli, Annarita Fiorillo, Riccardo Ocello, Francesca Seghetti, Jessica Caciolla, Elisa Uliassi, Matteo Masetti, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Andrea Ilari, Maria Laura Bolognesi

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, medicinal chemistry campaign, drug discovery approaches, trypanosoma brucei <, leishmania infantum <, ex vivo <, based drug discovery, 9 , 14 , 10 , tr binding site, leishmaniasis trypanothione reductase, vitro <, silico <, k <, , tr inhibition, suitable target, still challenging, potent inhibitors, improve selectivity, difficult target

Relation: https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925498

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01439.s003
https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925498

المؤلفون: Cécile Exertier, Alessandra Salerno, Lorenzo Antonelli, Annarita Fiorillo, Riccardo Ocello, Francesca Seghetti, Jessica Caciolla, Elisa Uliassi, Matteo Masetti, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Andrea Ilari, Maria Laura Bolognesi

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, medicinal chemistry campaign, drug discovery approaches, trypanosoma brucei <, leishmania infantum <, ex vivo <, based drug discovery, 9 , 14 , 10 , tr binding site, leishmaniasis trypanothione reductase, vitro <, silico <, k <, , tr inhibition, suitable target, still challenging, potent inhibitors, improve selectivity, difficult target

Relation: https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925507

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01439.s006
https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925507

المؤلفون: Cécile Exertier, Alessandra Salerno, Lorenzo Antonelli, Annarita Fiorillo, Riccardo Ocello, Francesca Seghetti, Jessica Caciolla, Elisa Uliassi, Matteo Masetti, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Andrea Ilari, Maria Laura Bolognesi

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, medicinal chemistry campaign, drug discovery approaches, trypanosoma brucei <, leishmania infantum <, ex vivo <, based drug discovery, 9 , 14 , 10 , tr binding site, leishmaniasis trypanothione reductase, vitro <, silico <, k <, , tr inhibition, suitable target, still challenging, potent inhibitors, improve selectivity, difficult target

Relation: https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925519

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01439.s010
https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925519

المؤلفون: Cécile Exertier, Alessandra Salerno, Lorenzo Antonelli, Annarita Fiorillo, Riccardo Ocello, Francesca Seghetti, Jessica Caciolla, Elisa Uliassi, Matteo Masetti, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Andrea Ilari, Maria Laura Bolognesi

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, medicinal chemistry campaign, drug discovery approaches, trypanosoma brucei <, leishmania infantum <, ex vivo <, based drug discovery, 9 , 14 , 10 , tr binding site, leishmaniasis trypanothione reductase, vitro <, silico <, k <, , tr inhibition, suitable target, still challenging, potent inhibitors, improve selectivity, difficult target

Relation: https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925513

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01439.s008
https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925513

المؤلفون: Cécile Exertier, Alessandra Salerno, Lorenzo Antonelli, Annarita Fiorillo, Riccardo Ocello, Francesca Seghetti, Jessica Caciolla, Elisa Uliassi, Matteo Masetti, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Andrea Ilari, Maria Laura Bolognesi

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, medicinal chemistry campaign, drug discovery approaches, trypanosoma brucei <, leishmania infantum <, ex vivo <, based drug discovery, 9 , 14 , 10 , tr binding site, leishmaniasis trypanothione reductase, vitro <, silico <, k <, , tr inhibition, suitable target, still challenging, potent inhibitors, improve selectivity, difficult target

Relation: https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925504

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01439.s005
https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925504

المؤلفون: Cécile Exertier, Alessandra Salerno, Lorenzo Antonelli, Annarita Fiorillo, Riccardo Ocello, Francesca Seghetti, Jessica Caciolla, Elisa Uliassi, Matteo Masetti, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Andrea Ilari, Maria Laura Bolognesi

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, medicinal chemistry campaign, drug discovery approaches, trypanosoma brucei <, leishmania infantum <, ex vivo <, based drug discovery, 9 , 14 , 10 , tr binding site, leishmaniasis trypanothione reductase, vitro <, silico <, k <, , tr inhibition, suitable target, still challenging, potent inhibitors, improve selectivity, difficult target

Relation: https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925516

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01439.s009
https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925516

المؤلفون: Cécile Exertier, Alessandra Salerno, Lorenzo Antonelli, Annarita Fiorillo, Riccardo Ocello, Francesca Seghetti, Jessica Caciolla, Elisa Uliassi, Matteo Masetti, Eleonora Fiorentino, Stefania Orsini, Trentina Di Muccio, Andrea Ilari, Maria Laura Bolognesi

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, medicinal chemistry campaign, drug discovery approaches, trypanosoma brucei <, leishmania infantum <, ex vivo <, based drug discovery, 9 , 14 , 10 , tr binding site, leishmaniasis trypanothione reductase, vitro <, silico <, k <, , tr inhibition, suitable target, still challenging, potent inhibitors, improve selectivity, difficult target

Relation: https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925522

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01439.s011
https://figshare.com/articles/dataset/Fragment_Merging_Growing_and_Linking_Identify_New_Trypanothione_Reductase_Inhibitors_for_Leishmaniasis/24925522