المؤلفون: Li, Junhao, Kumar, Amit, Långström, Bengt, Nordberg, Agneta, Ågren, Hans

المصدر: ACS Chemical Neuroscience. 14(18):3528-3539

مصطلحات موضوعية: 4R tau fibrils, metadynamics, positron emission tomography tracer, free energy surface, Alzheimer disease, molecular dynamics

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-511105
https://doi.org/10.1021/acschemneuro.3c00437
https://uu.diva-portal.org/smash/get/diva2:1795211/FULLTEXT01.pdf

المؤلفون: Allison R. Balaj, Thomas L. Rothstein, Hiroaki Kaku

المصدر: Free Neuropathology, Vol 5 (2024)

مصطلحات موضوعية: Truncated tau fibrils, Filter trap assay, Sarkosyl, Tauopathies, Protein aggregation, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.wwu.de/Ejournals/index.php/fnp/article/view/5497; https://doaj.org/toc/2699-4445

URL الوصول: https://doaj.org/article/df2a3d9c2ce14a4d9952150c10400678

المؤلفون: Lea Langer Horvat, Ena Španić Popovački, Mirjana Babić Leko, Klara Zubčić, Luka Horvat, Maja Mustapić, Patrick R. Hof, Goran Šimić

المصدر: Biomedicines; Volume 11; Issue 4; Pages: 1004

مصطلحات موضوعية: Alzheimer’s disease, cognition, neurofibrillary degeneration, spatial working memory, tau fibrils, tau oligomers, tau protein, tauopathy model, Wistar rat

وصف الملف: application/pdf

Relation: Neurobiology and Neurologic Disease; https://dx.doi.org/10.3390/biomedicines11041004

الاتاحة: https://doi.org/10.3390/biomedicines11041004

المؤلفون: Allwin Ebenezer Sahayaraj (14253663), Renjith Viswanathan (14253666), Faina Pinhero (14253669), Arshad Abdul Vahid (11379302), Vinesh Vijayan (271748)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Microbiology, Cell Biology, Genetics, Molecular Biology, Neuroscience, Biotechnology, Computational Biology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, using molecular dynamics, neurodegenerative diseases correlated, molecular dynamics simulations, homologous e264g mutation, e264g mutation induces, 326 , 273 , 270 , 264 , 262 , narrow pick filament, terminal hexapeptide flanked, e264g mutant construct, compact local conformation, binding repeat region, pathological tau fibrils, dependent conformational properties, terminal hexapeptide

Relation: https://figshare.com/articles/journal_contribution/Sequence-Dependent_Conformational_Properties_of_PGGG_Motif_in_Tau_Repeats_Insights_from_Molecular_Dynamics_Simulations_of_Narrow_Pick_Filament/21719871

الاتاحة: https://doi.org/10.1021/acschemneuro.2c00602.s001

المؤلفون: Yang Zhou (65942), Junhao Li (844050), Agneta Nordberg (234998), Hans Ågren (472815)

مصطلحات موضوعية: Biophysics, Biochemistry, Neuroscience, Cancer, Mental Health, Chemical Sciences not elsewhere classified, study clearly shows, first computational study, provide atomic resolution, higher binding affinity, ad tau fibrils, various binding sites, identified binding sites, tau specific tracers, ad tau compared, studied tracers showed, 4r tracer mk6240, binding sites, low resolution, ad tauopathies, ad ), 4r compared, binding profiles, binding profile, binding modes, tau pathology, 4r tau, surface sites, thermodynamic properties, silico <

Relation: https://figshare.com/articles/journal_contribution/Dissecting_the_Binding_Profile_of_PET_Tracers_to_Corticobasal_Degeneration_Tau_Fibrils/16548016

الاتاحة: https://doi.org/10.1021/acschemneuro.1c00536.s001

المؤلفون: Siddhartha Banerjee (1902061), Ayanjeet Ghosh (1296357)

مصطلحات موضوعية: Biophysics, Biochemistry, Neuroscience, Biotechnology, Ecology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, structurally distinct polymorphs, nanoscale infrared spectroscopy, multiple fibrillar polymorphs, investigate nanoscale spectra, antiparallel β sheets, tau protein plays, significant structural heterogeneities, including alzheimer ’, tau aggregates revealed, tau aggregates associated, stage tau aggregates, individual tau fibrils, investigating protein aggregation, tau aggregates, tau misfolds, structural distributions, parkinson ’, mature fibrils, present study, neurofibrillary tangles, first application

Relation: https://figshare.com/articles/journal_contribution/Structurally_Distinct_Polymorphs_of_Tau_Aggregates_Revealed_by_Nanoscale_Infrared_Spectroscopy/16954939

الاتاحة: https://doi.org/10.1021/acs.jpclett.1c02660.s001

المؤلفون: David J. Ingham (10826157), Bryce R. Blankenfeld (10826160), Shibin Chacko (1608439), Chamani Perera (2216167), Berl R. Oakley (183341), Truman Christopher Gamblin (10826163)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Pharmacology, Biotechnology, Cancer, Mental Health, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, modeling inducer molecule, Fungally Derived Isoquinoline Demon., LMTM, LMTX, amyloid fibril-like structure, target tau pathology, preformed ARA fibrils, tau aggregation inhibitor, microtubule-associated protein tau, fungus Aspergillus nidulans, tau fibrils, strain, tau filaments, ANTC

Relation: https://figshare.com/articles/journal_contribution/Fungally_Derived_Isoquinoline_Demonstrates_Inducer-Specific_Tau_Aggregation_Inhibition/14620638

الاتاحة: https://doi.org/10.1021/acs.biochem.1c00111.s001

المؤلفون: Celauro, Luigi, Cazzaniga, Federico Angelo, Bistaffa, Edoardo, Moda, Fabio

مصطلحات موضوعية: NEURODEGENERATION, PRION DISEASES, PRPC, PRPSC, PRIONS, TAU, TAUOPATHY, AGGREGATION, TAU FIBRILS, CONFORMERS

Relation: https://doi.org/10.1016/J.JBC.2023.105054; https://zenodo.org/communities/besta; https://doi.org/10.5281/zenodo.10697416; https://doi.org/10.5281/zenodo.10697417; oai:zenodo.org:10697417

الاتاحة: https://doi.org/10.5281/zenodo.10697417

المؤلفون: Celauro L., Burato A., Zattoni M., De Cecco E., Fantuz M., Cazzaniga F. A., Bistaffa E., Moda F., Legname G.

المساهمون: Celauro, L., Burato, A., Zattoni, M., De Cecco, E., Fantuz, M., Cazzaniga, F. A., Bistaffa, E., Moda, F., Legname, G.

مصطلحات موضوعية: aggregation, conformers, neurodegeneration, prion diseases, prions, PrP, Sc, tau, tau fibrils, tauopathy, Settore BIO/10 - Biochimica

Relation: info:eu-repo/semantics/altIdentifier/pmid/37454740; volume:299; issue:8; firstpage:1; lastpage:12; numberofpages:12; journal:THE JOURNAL OF BIOLOGICAL CHEMISTRY; https://hdl.handle.net/20.500.11767/133892; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85166939799

الاتاحة: https://hdl.handle.net/20.500.11767/133892
https://doi.org/10.1016/j.jbc.2023.105054

المؤلفون: Langer Horvat, Lea, Šimić, Goran

المساهمون: Šimić, Goran, Mimica, Ninoslav

مصطلحات موضوعية: Alzheimer’s disease, cognition, tau fibrils, tau oligomers, tauopathy rat model

URL الوصول: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::c52e7b8b242fdde656194d496b131a1b
https://www.bib.irb.hr/1264721

المؤلفون: Langer Horvat, Lea, Španić Popovački, Ena, Babić Leko, Mirjana, Zubčić, Klara, Horvat, Luka, Mustapić, Maja, Hof, Patrick R., Šimić, Goran

مصطلحات موضوعية: Alzheimer’s disease, cognition, neurofibrillary degeneration, spatial working memory, tau fibrils, tau oligomers, tau protein, tauopathy model, Wistar rat

URL الوصول: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::e26514204f449c67d81d34d37e81d124
https://www.bib.irb.hr/1263284

المؤلفون: Langer Horvat, Lea

المساهمون: Šimić, Goran, Šalković-Petrišić, Melita, Borovečki, Fran, Mimica, Ninoslav, Švob Štrac, Dubravka, Hranilović, Dubravka

مصطلحات موضوعية: cognition, tau oligomers, animal non-transgenic model, tauopathies, tau fibrils, Wistar rat, spatial working memory, neurofibrillary degeneration, animalni netransgeni model, neurofibrilarna degeneracija, prostorno radno pamćenje, spoznajne sposobnosti, tau fibrili, tau oligomeri, tau protein, tauopatije, Wistar štakor

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::dd95e5a9e696575012fcd41411465ddd
https://www.bib.irb.hr/1249254

المؤلفون: Virginie Redeker, Karine Madiona, Ronald Melki, Emilie Caroux

المساهمون: Centre National de la Recherche Scientifique (CNRS), Service MIRCEN (MIRCEN), Université Paris-Saclay-Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), ANR-17-JPCD-0005,Protest-70,Protecting protein homeostasis in synucleinopathies and tauopathies by modulating the Hsp70/co-chaperone network(2017), ANR-17-JPCD-0002,TransPathND,Intraneuronal transport-related pathways across neurodegenerative diseases(2017), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB)

المصدر: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2021, 297, pp.101252. ⟨10.1016/j.jbc.2021.101252⟩
The Journal of Biological Chemistry
Journal of Biological Chemistry, 2021, 297, pp.101252. ⟨10.1016/j.jbc.2021.101252⟩

مصطلحات موضوعية: PiD, Pick's disease, Cryo-electron microscopy, Pronase, Biochemistry, PVDF, polyvinylidene difluoride, 0302 clinical medicine, Protein structure, MS2, fragmentation mass spectrum, N-TOP, N-terminal-oriented proteomics, cryo-EM, cryo-electron microscopy, SDS-PAGE, sodium dodecyl sulfate–polyacrylamide gel electrophoresis, mass spectrometry, MALDI-TOF-TOF, matrix assisted laser desorption/ionization-time-of-flight-time-of-flight, chemistry.chemical_classification, 0303 health sciences, CID, collision-Induced dissociation, medicine.diagnostic_test, Chemistry, TMPP(, N-succinimidyloxycarbonylmethyl)-tris(2,4,6-trimethoxyphenyl)-phosphonium, DTT, 1,4-dithiotheritol, NHS-biotin, N-hydroxysulfosuccinimide biotin, Amino acid, PSP, progressive supranuclear palsy, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], AD, Alzheimer's disease, Research Article, CBD, corticobasal degeneration, AGD, argyrophilic grain disease, FDR, false discovery rate, Proteolysis, tau fibrils, tau Proteins, macromolecular substances, Fibril, Peptide Mapping, TFA, trifluoroacetic acid, 03 medical and health sciences, Protein Aggregates, Protein Domains, PBS, phosphate buffered saline, protein conformation, medicine, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, TEM, transmission electron microscopy, Molecular Biology, TD, tangle disease, 030304 developmental biology, htau, human tau, nanoLC-MS/MS, nanoflow liquid chromatography combined to tandem mass spectrometry bromide, tauopathies, Alternative splicing, Cell Biology, medicine.disease, structural proteomics, MS, mass spectrometry, chemical surface modification, Biophysics, AEBSF, 4-(2-aminoethyl)benzenesulfonyl fluoride hydrochloride, Pick's disease, 030217 neurology & neurosurgery, limited proteolysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb73365cfdfb93b7855667803503848
https://hal-cea.archives-ouvertes.fr/cea-03384553

المؤلفون: Horvat Velić, Emina

المساهمون: Šimić, Goran, Hranilović, Dubravka

مصطلحات موضوعية: imunohistokemija, PRIRODNE ZNANOSTI. Biologija, Alzheimer's disease, entorhinal cortex, hippocampus, propagation of neurofibrillary changes, rat model, tau fibrils, tau oligomers, mental disorders, NATURAL SCIENCES. Biology, Dementia, Alzheimer’s Disease, tau, Alzheimerova bolest, demencija, Tau Protein, Immunohistochemistry

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::aada861c5d39a5e51c2cb0b8c6dda0f6
https://www.bib.irb.hr/1160929

المؤلفون: Langer Horvat, Lea, Španić, Ena, Babić Leko, Mirjana, Šimić, Goran

المساهمون: Šimić, Goran, Mimica, Ninoslav

مصطلحات موضوعية: Alzheimer's disease, amyloid, cognitive changes, entorhinal cortex, Iba1, microglia, neurofibrillary changes, rat, stereotaxy, tau fibrils, tau oligomers, tauopathy, mental disorders

URL الوصول: https://explore.openaire.eu/search/publication?articleId=57a035e5b1ae::20944edd6a2dc867021cdf0d3f2270ad
https://www.bib.irb.hr/1091206

المؤلفون: Caroux, Emilie

Thesis Advisors: Paris Saclay, Redeker, Virginie, Melki, Ronald

مصطلحات موضوعية: Fibres de Tau, Tauopathies, Protéomique structurale, Spectrométrie de masse, Protéolyse Ménagée, Marquage chimique de surface, Tau fibrils, Structural proteomics, Mass spectrometry, Limited Proteolysis, Chemical Surface Labeling

الاتاحة: http://www.theses.fr/2019SACLS592

المؤلفون: Lulu Jiang, Marcello Orlando, Leonard Petrucelli, Brandon F. Maziuk, Heather I. Ballance, Tsuneya Ikezu, Ali Al Abdullatif, Benjamin Wolozin, Samantha Boudeau, Peter E.A. Ash

المصدر: Acta neuropathologica

مصطلحات موضوعية: 0301 basic medicine, TIA1, Tau propagation, Tau oligomers, RNA-binding protein, Mice, Transgenic, tau Proteins, Hippocampal formation, Fibril, Article, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Stress granule, mental disorders, medicine, Animals, Neurodegeneration, Neuropathology, Neurons, Chemistry, Brain, Motor neuron, medicine.disease, 3. Good health, Cell biology, T-Cell Intracellular Antigen-1, Mice, Inbred C57BL, Disease Models, Animal, Tauopathy, 030104 developmental biology, medicine.anatomical_structure, Tauopathies, Stress granules, Tau fibrils, Neurology (clinical), RNA binding proteins, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc9c5719e084f943a26b5a14c81ba140
https://pubmed.ncbi.nlm.nih.gov/30465259

المؤلفون: Caroux, Emilie

المساهمون: Laboratoire des Maladies Neurodégénératives - UMR 9199 (LMN), Molecular Imaging Research Center Fontenay-aux-Roses (MIRCEN), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie François JACOB (JACOB), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Université Paris Saclay (COmUE), Virginie Redeker, Ronald Melki

المصدر: https://theses.hal.science/tel-03494708 ; Biochimie [q-bio.BM]. Université Paris Saclay (COmUE), 2019. Français. ⟨NNT : 2019SACLS592⟩.

مصطلحات موضوعية: Tau fibrils, Tauopathies, Structural proteomics, Mass spectrometry, Limited Proteolysis, Chemical Surface Labeling, Fibres de Tau, Protéomique structurale, Spectrométrie de masse, Protéolyse Ménagée, Marquage chimique de surface, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM]

Relation: NNT: 2019SACLS592; tel-03494708; https://theses.hal.science/tel-03494708; https://theses.hal.science/tel-03494708/document; https://theses.hal.science/tel-03494708/file/82825_CAROUX_2019_archivage.pdf

الاتاحة: https://theses.hal.science/tel-03494708
https://theses.hal.science/tel-03494708/document
https://theses.hal.science/tel-03494708/file/82825_CAROUX_2019_archivage.pdf

المؤلفون: Langer Horvat, Lea

المساهمون: Šimić, Goran

مصطلحات موضوعية: BIOMEDICINA I ZDRAVSTVO. Temeljne medicinske znanosti. Neuroznanost, BIOMEDICINE AND HEALTHCARE. Basic Medical Sciences. Neuroscience, Medicina, Medical sciences, info:eu-repo/classification/udc/61(043.3), animalni netransgeni model, neurofibrilarna degeneracija, prostorno radno pamćenje, spoznajne sposobnosti, tau fibrili, tau oligomeri, tau protein, tauopatije, Wistar štakor, animal non-transgenic model, cognition, neurofibrillary degeneration, spatial working memory, tau fibrils, tau oligomers, tauopathies, Wistar rat

وصف الملف: application/pdf

Relation: info:eu-repo/grantAgreement/HRZZ/IP/IP-2014-09-9730/HR/Hiperfosforilacija, agregacija i transsinaptički prijenos tau proteina u Alzheimerovoj bolesti: analiza likvora i ispitivanje potencijalnih neuroprotektivnih spojeva/ALZTAUPROTECT; https://dr.nsk.hr/islandora/object/mef:5273; https://urn.nsk.hr/urn:nbn:hr:105:797971; https://repozitorij.unizg.hr/islandora/object/mef:5273; https://repozitorij.unizg.hr/islandora/object/mef:5273/datastream/PDF

الاتاحة: https://dr.nsk.hr/islandora/object/mef:5273
https://urn.nsk.hr/urn:nbn:hr:105:797971
https://repozitorij.unizg.hr/islandora/object/mef:5273
https://repozitorij.unizg.hr/islandora/object/mef:5273/datastream/PDF

المؤلفون: Aurelio J. Dregni (8939669), Harrison K. Wang (10798809), Haifan Wu (1566376), Pu Duan (1554403), Jia Jin (752067), William F. DeGrado (276486), Mei Hong (293174)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Neuroscience, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Resonance Spectroscopy, correlation NMR experiments, Solid-State Nuclear, R 3, 13 C, R 4 domains, patient brains, β- sheet core, β- sheet conformation, C-terminal domain, β- sheet core structure, brain-derived tau fibrils, 0 N 3R tau fibrillized, β- sheet filaments, R 1, tau fibril structures, R 4, patient brains show, R 3 domains, C-terminal residues, neurodegenerative diseases, prion-like manner, tau fibrils

Relation: https://figshare.com/articles/journal_contribution/Inclusion_of_the_C_Terminal_Domain_in_the_Sheet_Core_of_Heparin-Fibrillized_Three-Repeat_Tau_Protein_Revealed_by_Solid-State_Nuclear_Magnetic_Resonance_Spectroscopy/14593461

الاتاحة: https://doi.org/10.1021/jacs.1c03314.s001