المؤلفون: Junyan Ma, Weiting Zhang, Simin Rahimialiabadi, Nikkitha Umesh Ganesh, Zhengwang Sun, Saba Parvez, Randall T. Peterson, Jing-Ruey Joanna Yeh

المصدر: Biology Open, Vol 13, Iss 9 (2024)

مصطلحات موضوعية: crispr, cas9, phic31, integrase, targeted integration, genotyping, transgenesis, reporter, zebrafish, knock-in, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://bio.biologists.org/content/13/9/bio061666; https://doaj.org/toc/2046-6390

URL الوصول: https://doaj.org/article/406817cbd67f49b0a8db399159b68807

المؤلفون: Jun Hirose, Emi Aizawa, Shogo Yamamoto, Mingyao Xu, Shigenori Iwai, Keiichiro Suzuki

المصدر: Biomolecules, Vol 14, Iss 12, p 1558 (2024)

مصطلحات موضوعية: genome editing, lipid nanoparticle (LNP), homology-independent targeted integration (HITI), knock-in, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/12/1558; https://doaj.org/toc/2218-273X

URL الوصول: https://doaj.org/article/198dd1759f3e48fba1700157a0a51797

المؤلفون: Anthony A. Stephenson, Stefan Nicolau, Tatyana A. Vetter, Gabrielle P. Dufresne, Emma C. Frair, Jessica E. Sarff, Gregory L. Wheeler, Benjamin J. Kelly, Peter White, Kevin M. Flanigan

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 486-499 (2023)

مصطلحات موضوعية: Duchenne muscular dystrophy, dystrophin, exon 2 duplication, gene editing, CRISPR-Cas9, homology-independent targeted integration, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050123001237; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/3a64dafda5294680b6d821cf373f9511

المؤلفون: de Alencastro, Gustavo, Puzzo, Francesco, Pavel-Dinu, Mara, Zhang, Feijie, Pillay, Sirika, Majzoub, Karim, Tiffany, Matthew, Jang, Hagoon, Sheikali, Adam, Cromer, M, Meetei, Ruhikanta, Carette, Jan, Porteus, Matthew, Pekrun, Katja, Kay, Mark

المصدر: Molecular Therapy. 29(3)

مصطلحات موضوعية: AAV, AAV-HR, CRISPR/Cas9, GeneRide, genome editing, homologous recombination, nuclease-free, targeted integration, CRISPR-Cas Systems, DNA Helicases, DNA-Binding Proteins, Dependovirus, Gene Editing, Genetic Vectors, HeLa Cells, Hematopoietic Stem Cells, Homologous Recombination, Humans, RecQ Helicases

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/48b6n7cm
https://escholarship.org/content/qt48b6n7cm/qt48b6n7cm.pdf

المؤلفون: Esposito, Federica, Dell'Aquila, Fabio, Rhiel, Manuel, Auricchio, Stefano, Chmielewski, Kay Ole, Andrieux, Geoffroy, Ferla, Rita, Horrach, Paula Sureda, Padmanabhan, Arjun, Di Cunto, Roberto, Notaro, Simone, Santeularia, Manel Llado, Boerries, Melanie, Dell'Anno, Margherita, Nusco, Edoardo, Padula, Agnese, Nutarelli, Sofia, Cornu, Tatjana I, Sorrentino, Nicolina Cristina, Piccolo, Pasquale, Trapani, Ivana, Cathomen, Toni, Auricchio, Alberto

المساهمون: Esposito, Federica, Dell'Aquila, Fabio, Rhiel, Manuel, Auricchio, Stefano, Chmielewski, Kay Ole, Andrieux, Geoffroy, Ferla, Rita, Horrach, Paula Sureda, Padmanabhan, Arjun, Di Cunto, Roberto, Notaro, Simone, Santeularia, Manel Llado, Boerries, Melanie, Dell'Anno, Margherita, Nusco, Edoardo, Padula, Agnese, Nutarelli, Sofia, Cornu, Tatjana I, Sorrentino, Nicolina Cristina, Piccolo, Pasquale, Trapani, Ivana, Cathomen, Toni, Auricchio, Alberto

مصطلحات موضوعية: AAV, CAST-Seq, CRISPR-Cas9, HITI, genome editing, hemophilia A, homology-independent targeted integration, inherited disease, in vivo, liver, mucopolysaccharidosis type VI, persistent transgene expression

Relation: journal:CELL REPORTS MEDICINE; https://hdl.handle.net/11588/964105

الاتاحة: https://hdl.handle.net/11588/964105
https://doi.org/10.1016/j.xcrm.2024.101619

المؤلفون: Han Ping Loh, Farouq Bin Mahfut, Serene W Chen, Yuhan Huang, Jianxin Huo, Wei Zhang, Kong Peng Lam, Shengli Xu, Yuansheng Yang

المصدر: mAbs, Vol 15, Iss 1 (2023)

مصطلحات موضوعية: CHO cell, avidity, bispecific antibody, functionality, manufacturability, targeted integration, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/8d90c44d609a46ee84e4e146feab623d

المؤلفون: David H. Gray, Jasmine Santos, Alexandra Grace Keir, Isaac Villegas, Simon Maddock, Edward C. Trope, Joseph D. Long, Caroline Y. Kuo

المصدر: Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 505-516 (2022)

مصطلحات موضوعية: gene editing, CRISPR-Cas9, X-linked agammaglobulinemia, homology-directed repair, HDR, homology-independent targeted integration, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253121003176; https://doaj.org/toc/2162-2531

URL الوصول: https://doaj.org/article/a50a2f85a4cc440a980c27bee1ffed02

المؤلفون: Lee, Jae Seong, Park, Jin Hyoung, Ha, Tae Kwang, Samoudi, Mojtaba, Lewis, Nathan E, Palsson, Bernhard O, Kildegaard, Helene Faustrup, Lee, Gyun Min

المصدر: ACS Synthetic Biology. 7(12)

مصطلحات موضوعية: Genetics, Biotechnology, 2.1 Biological and endogenous factors, Aetiology, Animals, CHO Cells, Cricetinae, Cricetulus, Cytomegalovirus, Gene Editing, Gene Expression, Green Fluorescent Proteins, Peptide Elongation Factor 1, Promoter Regions, Genetic, Regulatory Sequences, Nucleic Acid, Temperature, Transgenes, Chinese hamster ovary cells, clonal variation, integration site, targeted integration, vector configuration, Medicinal and Biomolecular Chemistry, Biochemistry and Cell Biology, Biomedical Engineering

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9d89t06q

المؤلفون: Adrian Kovač, Csaba Miskey, Zoltán Ivics

المصدر: International Journal of Molecular Sciences, Vol 24, Iss 14978, p 14978 (2023)

مصطلحات موضوعية: genetic engineering, targeted integration, nucleolus, ribosomal RNA, transposition, chromosomal integration, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/24/19/14978; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/d5060f4c22fa4e278a271ed381025ae4

الاتاحة: https://doi.org/10.3390/ijms241914978
https://doaj.org/article/d5060f4c22fa4e278a271ed381025ae4

المؤلفون: Honggi Min, Seul Mi Kim, Dongwoo Kim, Solhwi Lee, Sumin Lee, Jae Seong Lee

المصدر: Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)

مصطلحات موضوعية: Chinese hamster ovary, CRISPR/Cas9, DHFR knockout, Gene Amplification, methotrexate, targeted integration, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fbioe.2022.977193/full; https://doaj.org/toc/2296-4185

URL الوصول: https://doaj.org/article/48f14f0ee1674b55afba6734af95f722

المؤلفون: Suvd Byambaa, Hideki Uosaki, Tsukasa Ohmori, Hiromasa Hara, Hitoshi Endo, Osamu Nureki, Yutaka Hanazono

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 451-462 (2021)

مصطلحات موضوعية: CRISPR/Cas9, non-viral genome editing, hematopoietic stem cells, homology-independent targeted integration, X-linked severe combined immunodeficiency, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050121000012; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/2f08446944e44cac965321da03925c00

المؤلفون: Fang Liu, Sekhar Kambakam, Maira P Almeida, Zhitao Ming, Jordan M Welker, Wesley A Wierson, Laura E Schultz-Rogers, Stephen C Ekker, Karl J Clark, Jeffrey J Essner, Maura McGrail

المصدر: eLife, Vol 11 (2022)

مصطلحات موضوعية: zebrafish, Cre/lox, conditional rescue and inactivation, CRISPR-Cas9, precision targeted integration, GeneWeld, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/71478; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/8f02d9ae8d7447cabd05434a5fed06f6

المؤلفون: Nina B. Reese, Sherman Ku

المصدر: Current Research in Biotechnology, Vol 3, Iss , Pp 269-280 (2021)

مصطلحات موضوعية: Targeted integration, Recombination, Antibody, CHO, Recombinase mediated cassette exchange, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590262821000290; https://doaj.org/toc/2590-2628

URL الوصول: https://doaj.org/article/2ff1ea56e0ab4582a3e41486760a50d4

المؤلفون: Qingnan Wang, Xiaomei Zhong, Qian Li, Jing Su, Yi Liu, Li Mo, Hongxin Deng, Yang Yang

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 520-531 (2020)

مصطلحات موضوعية: AAV, CRISPR-Cas9, hemophilia B, targeted integration, albumin, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050120301492; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/c914a7028aa240718843a348366827c2

المساهمون: Sung-Ah Hong, Jung Hwa Seo, Soohyun Wi, Eul Sik Jung, Jihyeon Yu, Gue-Ho Hwang, Ji Hea Yu, Ahreum Baek, Soeon Park, Sangsu Bae, Sung-Rae Cho, Cho, Sung Rae

مصطلحات موضوعية: ABCD1, CRISPR, adrenoleukodystrophy, base editing, gene therapy, genome editing, homology-independent targeted integration, very long-chain fatty acid

Relation: MOLECULAR THERAPY; J02271; OAK-2021-07178; https://ir.ymlib.yonsei.ac.kr/handle/22282913/186746; https://www.sciencedirect.com/science/article/pii/S152500162100304X; T202103773; MOLECULAR THERAPY, Vol.30 : 119-129, 2022-01

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/186746
https://www.sciencedirect.com/science/article/pii/S152500162100304X

المؤلفون: Pavani, Giulia, Amendola, Mario

المساهمون: Approches génétiques intégrées et nouvelles thérapies pour les maladies rares (INTEGRARE), Université d'Évry-Val-d'Essonne (UEVE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Généthon

المصدر: EISSN: 2673-3439 ; Frontiers in Genome Editing ; https://hal.science/hal-04407860 ; Frontiers in Genome Editing, 2021, 2, ⟨10.3389/fgeed.2020.609650⟩

مصطلحات موضوعية: genome editing gene therapy nuclease CRISPR targeted integration (TI) knock-in safe harbor homologous recombination (HR), genome editing, gene therapy, nuclease, CRISPR, targeted integration (TI), knock-in, safe harbor, homologous recombination (HR), [SDV]Life Sciences [q-bio]

Relation: hal-04407860; https://hal.science/hal-04407860; https://hal.science/hal-04407860/document; https://hal.science/hal-04407860/file/fgeed-02-609650-3.pdf

الاتاحة: https://hal.science/hal-04407860
https://hal.science/hal-04407860/document
https://hal.science/hal-04407860/file/fgeed-02-609650-3.pdf
https://doi.org/10.3389/fgeed.2020.609650

المؤلفون: Cao, Xiang-Xiang, Yuan, Jing-Jia, Bai, Zhi-Yuan, Zhang, Min, Yun, Yi-Fei, Wang, Xiao-Yin, Mi, Chun-Liu, Sun, Qiu-Li, Geng, Shao-Lei, Wang, Tian-Yun

المصدر: Int J Biol Macromol ; ISSN:1879-0003

مصطلحات موضوعية: CHO cells, CRISPR/Cas9, Glycosylation, Targeted integration

Relation: https://doi.org/10.1016/j.ijbiomac.2024.139274; https://pubmed.ncbi.nlm.nih.gov/39736287

الاتاحة: https://doi.org/10.1016/j.ijbiomac.2024.139274
https://pubmed.ncbi.nlm.nih.gov/39736287

المؤلفون: Kristine E. Yoder, Anthony J. Rabe, Richard Fishel, Ross C. Larue

المصدر: Frontiers in Molecular Biosciences, Vol 8 (2021)

مصطلحات موضوعية: retrovirus, gene therapy, targeted integration, HIV-1, MLV, LEDGF/p75, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2021.662331/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/bcf1d9da2b6b49bd90f5d328072acb32

المؤلفون: Giulia Pavani, Mario Amendola

المصدر: Frontiers in Genome Editing, Vol 3 (2021)

مصطلحات موضوعية: genome editing, gene therapy, nuclease, CRISPR, targeted integration (TI), knock-in, Biotechnology, TP248.13-248.65, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgeed.2021.682171/full; https://doaj.org/toc/2673-3439

URL الوصول: https://doaj.org/article/fb30109d9c404c83b3c5eead226f6db9

المؤلفون: Welker, Jordan M., Wierson, Wesley A., Almeida, Maira P., Mann, Carla M., Torrie, Melanie E., Ming, Zhitao, Ekker, Stephen C., Clark, Karl J., Dobbs, Drena, Essner, Jeffrey, McGrail, Maura

المساهمون: Genetics, Development and Cell Biology

المصدر: https://doi.org/10.21769/BioProtoc.4100.

مصطلحات موضوعية: DegreeDisciplines::Life Sciences::Genetics and Genomics, DegreeDisciplines::Life Sciences::Cell and Developmental Biology, CRISPR/Cas9, Knock-in, Homology mediated-end joining, Targeted integration, Zebrafish

وصف الملف: application/pdf

Relation: GeneWeld: a method for efficient targeted integration directed by short homology; https://dr.lib.iastate.edu/handle/20.500.12876/qzoD00Xw

الاتاحة: https://dr.lib.iastate.edu/handle/20.500.12876/qzoD00Xw
https://hdl.handle.net/20.500.12876/qzoD00Xw