المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/journal_contribution/Mouse_strains_used_in_this_study_/24917909

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s014
https://figshare.com/articles/journal_contribution/Mouse_strains_used_in_this_study_/24917909

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/journal_contribution/Original_SDS_PAGE_and_immunoblot_gel_images_/24917906

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s013
https://figshare.com/articles/journal_contribution/Original_SDS_PAGE_and_immunoblot_gel_images_/24917906

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/journal_contribution/Bacterial_strains_generated_and_used_in_this_study_/24917912

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s015
https://figshare.com/articles/journal_contribution/Bacterial_strains_generated_and_used_in_this_study_/24917912

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/journal_contribution/Cell_lines_generated_and_used_in_this_study_/24917915

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s016
https://figshare.com/articles/journal_contribution/Cell_lines_generated_and_used_in_this_study_/24917915

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/journal_contribution/Plasmids_generated_and_used_in_this_study_/24917921

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s018
https://figshare.com/articles/journal_contribution/Plasmids_generated_and_used_in_this_study_/24917921

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/journal_contribution/Oligonucleotides_designed_in_this_study_/24917918

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s017
https://figshare.com/articles/journal_contribution/Oligonucleotides_designed_in_this_study_/24917918

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/Death-effector_deoxyribonucleosides_do_not_trigger_cleavage_of_pro-caspase-8_in_human_macrophages_/24917870

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s001
https://figshare.com/articles/figure/Death-effector_deoxyribonucleosides_do_not_trigger_cleavage_of_pro-caspase-8_in_human_macrophages_/24917870

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/_i_S_i_i_aureus_i_deploys_AdsA_to_trigger_intrinsic_apoptosis_in_liver_abscess-infiltrating_macrophages_/24917876

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s003
https://figshare.com/articles/figure/_i_S_i_i_aureus_i_deploys_AdsA_to_trigger_intrinsic_apoptosis_in_liver_abscess-infiltrating_macrophages_/24917876

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/Death-effector_deoxyribonucleosides_stimulate_the_intrinsic_pathway_of_apoptosis_in_murine_phagocytes_/24917873

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s002
https://figshare.com/articles/figure/Death-effector_deoxyribonucleosides_stimulate_the_intrinsic_pathway_of_apoptosis_in_murine_phagocytes_/24917873

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/AdsA-derived_death-effector_deoxyribonucleosides_kill_human_phagocytes_in_a_dose-dependent_manner_/24917888

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s007
https://figshare.com/articles/figure/AdsA-derived_death-effector_deoxyribonucleosides_kill_human_phagocytes_in_a_dose-dependent_manner_/24917888

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/Nuclease-deficient_staphylococci_do_not_trigger_intrinsic_apoptosis_in_abscess-infiltrating_macrophages_/24917879

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s004
https://figshare.com/articles/figure/Nuclease-deficient_staphylococci_do_not_trigger_intrinsic_apoptosis_in_abscess-infiltrating_macrophages_/24917879

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/Discovery_of_human_i_CASP9_i_alleles_conferring_resistance_to_death-effector_deoxyribonucleosides_/24917897

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s010
https://figshare.com/articles/figure/Discovery_of_human_i_CASP9_i_alleles_conferring_resistance_to_death-effector_deoxyribonucleosides_/24917897

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/The_pan-caspase_inhibitor_Z-VAD-FMK_protects_phagocytes_from_death-effector_deoxyribonucleoside-mediated_cytotoxicity_/24917882

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s005
https://figshare.com/articles/figure/The_pan-caspase_inhibitor_Z-VAD-FMK_protects_phagocytes_from_death-effector_deoxyribonucleoside-mediated_cytotoxicity_/24917882

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/Tissue-specific_deletion_of_caspase-9_is_dispensable_for_staphylococcal_survival_in_blood_/24917891

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s008
https://figshare.com/articles/figure/Tissue-specific_deletion_of_caspase-9_is_dispensable_for_staphylococcal_survival_in_blood_/24917891

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/Disruption_of_the_intrinsic_pathway_of_apoptosis_protects_phagocytes_from_death-effector_deoxyribonucleoside-induced_mitochondrial_depolarization_and_apoptosis_/24917885

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s006
https://figshare.com/articles/figure/Disruption_of_the_intrinsic_pathway_of_apoptosis_protects_phagocytes_from_death-effector_deoxyribonucleoside-induced_mitochondrial_depolarization_and_apoptosis_/24917885

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/Engineering_of_an_sgRNA_Cas9-resistant_i_CASP9_i_allele_/24917894

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s009
https://figshare.com/articles/figure/Engineering_of_an_sgRNA_Cas9-resistant_i_CASP9_i_allele_/24917894

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/Heterogeneous_alleles_in_human_i_CASP9_i_prevent_death-effector_deoxyribonucleoside-induced_mitochondrial_depolarization_and_apoptosis_in_macrophages_/24917900

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s011
https://figshare.com/articles/figure/Heterogeneous_alleles_in_human_i_CASP9_i_prevent_death-effector_deoxyribonucleoside-induced_mitochondrial_depolarization_and_apoptosis_in_macrophages_/24917900

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/Filter-sterilized_culture_supernatants_derived_from_the_bacteria-purine_deoxyribonucleoside_monophosphate_co-incubation_step_do_not_contain_major_i_S_i_i_aureus_i_toxins_/24917903

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.s012
https://figshare.com/articles/figure/Filter-sterilized_culture_supernatants_derived_from_the_bacteria-purine_deoxyribonucleoside_monophosphate_co-incubation_step_do_not_contain_major_i_S_i_i_aureus_i_toxins_/24917903

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/_i_S_i_i_aureus_i_exploits_the_intrinsic_pathway_of_apoptosis_to_kill_phagocytes_/24917927

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.g002
https://figshare.com/articles/figure/_i_S_i_i_aureus_i_exploits_the_intrinsic_pathway_of_apoptosis_to_kill_phagocytes_/24917927

المؤلفون: Nicoletta Schwermann, Rita Haller, Sebastian Koch, Guntram A. Grassl, Volker Winstel

مصطلحات موضوعية: Medicine, Microbiology, Cell Biology, Immunology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, trigger mitochondrial rupture, kill infectious foci, infectious disease outcomes, evolved refined immuno, helps macrophages coping, staphylococcus aureus <, centered cell death, phagocytes , aureus <, casp9 <, systematically promotes, subsequent activation, protective alleles, processing apoptosome, penetrating macrophages, mediated cytotoxicity, laboratory animals, intrinsic pathway, induces assembly, genetic disruption, fatal event, evasive strategies

Relation: https://figshare.com/articles/figure/Conditional_knockout_mice_lacking_caspase-9_display_increased_resistance_to_i_S_i_i_aureus_i_infection_/24917930

الاتاحة: https://doi.org/10.1371/journal.ppat.1011892.g003
https://figshare.com/articles/figure/Conditional_knockout_mice_lacking_caspase-9_display_increased_resistance_to_i_S_i_i_aureus_i_infection_/24917930