المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/journal_contribution/The_RiBoSor_An_algorithm_to_create_alternative_reading_frames_within_a_gene_/16777259

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.s001

المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/journal_contribution/Theoretical_protection_from_mutations_conferred_by_overlapping_reading_frames_Effect_of_different_parameters_and_models_of_loss-of-function_/16777262

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.s002

المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/journal_contribution/Potential_riboverlaps_in_50_bacterial_genomes_and_in_iGEM_catalog_of_standard_biological_parts_/16777265

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.s003

المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/journal_contribution/GalK_is_a_counter-selectable_gene_in_presence_of_DOG_/16777268

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.s004

المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/journal_contribution/Candidates_found_by_the_RiBoSor_for_galK_/16777271

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.s005

المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/journal_contribution/Phenotype_of_the_galK-kanR_synthetic_overlap_/16777274

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.s006

المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/journal_contribution/Mutation_rate_is_not_affected_by_the_overlap_/16777277

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.s007

المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/journal_contribution/Predicted_temporal_stability_of_a_multi-gene_circuits_/16777280

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.s008

المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/figure/Principle_and_construction_of_a_Riboverlap_/16777283

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.g001

المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/figure/Theoretical_protection_from_mutations_conferred_by_overlapping_reading_frames_/16777286

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.g002

المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/figure/Large_overlapping_reading_frames_can_be_created_in_many_genes_/16777289

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.g003

المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/figure/Experimentally_measured_protection_from_mutations_and_expected_resulting_increase_in_circuit_lifetime_/16777295

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.g005

المؤلفون: Antoine L. Decrulle (11540003), Antoine Frénoy (488423), Thomas A. Meiller-Legrand (9871646), Aude Bernheim (6112178), Chantal Lotton (2822462), Arnaud Gutierrez (35056), Ariel B. Lindner (109561)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, overlap converts many, even lethal cost, div >< p, synthetic biology approaches, sustain genetic constructs, overlap thus protects, essential gene within, engineering gene overlaps, synthetic constructs, essential gene, thus increasing, existing gene, costly gene, vivo <, significant fraction, scoring mutations, rationally design, purging loss, possible mutants, overlapping construct, mutations impacting, function mutations

Relation: https://figshare.com/articles/figure/Synthesized_construct_and_experimental_design_/16777292

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009475.g004