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1Academic Journal
المؤلفون: Martyn C. Henry, Christopher M. Riley, Irene Hunter, Jessica M. L. Elwood, J. Daniel Lopez-Fernandez, Laura Minty, Diane M. Coe, Iain J. McEwan, Craig Jamieson
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, suppress tumor growth, resistant prostate cancer, prostate cancer pathogenesis, intrinsically disordered n, favorable physicochemical properties, exhibited increased potency, benchmarked pharmacokinetic profile, suitable starting point, 7 b, 16 b, small molecule inhibitors, suitable target, molecule anti, weak inhibitor, vcap cell, terminal domain, study revealed, indazole analogue, extensively validated, eventually fail, drug target, crpc therapeutic
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2Academic Journal
المؤلفون: Jianmin Xiao (755793), Qiong Sun (1674727), Lang Ran (12828988), Yinfeng Wang (4523953), Xia Qin (123775), Xiaotong Xu (619837), Chuhua Tang (7854344), Lu Liu (171341), Guilong Zhang (1571314)
مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Pharmacology, Cancer, Space Science, Biological Sciences not elsewhere classified, vivo results indicate, using hyaluronic acid, thioredoxin reductase 1, cellular adenosine triphosphate, cancer cell death, suppress tumor growth, subsequently releasing atv, se synergistically downregulate, inducing nutrient deprivation, atorvastatin delivery recently, responsive selenium nanoplatform, cancer cells, atv nanoplatform, tumor tissue, tumor suppression, suppressing tumors, significantly elevated, promising strategy, lowering drug, low level, loading atv, line lipid, effectively accumulates
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3Academic Journal
المؤلفون: Monize M. da Silva (11383202), Gabriel H. Ribeiro (4524397), Mariana S. de Camargo (11383205), Antônio G. Ferreira (11383208), Leandro Ribeiro (11383211), Marília I. F. Barbosa (11383214), Victor M. Deflon (561714), Silvia Castelli (9623), Alessandro Desideri (9626), Rodrigo S. Corrêa (2221273), Arthur B. Ribeiro (6695786), Heloiza D. Nicolella (5050604), Saulo D. Ozelin (10306016), Denise C. Tavares (666635), Alzir A. Batista (416078)
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Chemical Sciences not elsewhere classified, suppress tumor growth, mouse xenograph models, molecular docking showed, mainly via π, inhibit topoisomerase ib, human topoisomerase ib, high cytotoxic activity, cancer cell lines, calf thymus <, effectively inhibited htopib, ru5 b, ru3 b, 50 sub, ru ( n, alkyl hydrophobic interactions, 6 sub, complexes (< b, (< b, bis <
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4Academic Journal
المؤلفون: Haochen Guo (8208162), Takahiro Nomoto (1332702), Sjaikhurrizal El Muttaqien (11636114), Xiaohang Sun (11450847), Kana Komoto (11636117), Makoto Matsui (441073), Yutaka Miura (234544), Nobuhiro Nishiyama (338219)
مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, polymeric iron chelator, associated iron ions, induces extracellular h, suppress tumor growth, oxidant antitumor efficacy, cultured cancer cells, tumor decompose h, dose vitamin c, dose vc therapy, 2 sub, vitamin c, tumor cells, induced h, modulating tumor, vivo <, vitro <, antitumor effect, work indicates
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5Academic Journal
المؤلفون: Rui Zhang (13940), Lin Tang (65412), Binyan Zhao (10059076), Yaomei Tian (6740846), Bailing Zhou (6740855), Yandong Mu (10059079), Li Yang (6520)
مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Space Science, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, DP 7-C, RNA Delivery System, inhibitor delivery system, cholesterol-modified DP 7, tumor microenvironment, Tumor Microenvironment MicroRNAs, PEI 25K Components, immune-activated tumor microenvironment, Suppress Tumor Growth, microRNA, adjuvant
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6Academic Journal
المؤلفون: Zichen Wang (2473054), Haimei Li (2566729), Wenyan She (13153009), Xiaoyang Zhang (196062), Yang Liu (4829), Yi Liu (36759), Peng Jiang (16544)
مصطلحات موضوعية: Pharmacology, Cancer, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suppressing hexokinase activity, sup >• sup, sup >+ sup, natural enzyme catalyst, suppress tumor growth, relieving enhanced photothermal, reduces oxygen consumption, photothermal effect generated, respiration inhibitor 3, lowers atp levels, excellent photothermal properties, resolution photoacoustic imaging, nir synergistic enhancement, nanosheets accelerates catalysis, highly efficient pai, cdt synergistic therapy, 2 sub, mcg nss optimize, improve therapeutic efficiency, based catalyst cu, guided integrated treatment, 3 ‑ bromopyruvate, 3 sub, alleviate hypoxia levels, photoacoustic imaging, therapeutic efficiency
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7Academic Journal
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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8
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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9
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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10
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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11
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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12
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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13
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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14
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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15
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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16
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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17
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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18
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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19
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism
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20
المؤلفون: Haojie Wang, Xinyu Yang, Yan Li, Shuyin Ze, Bo Feng, Yuan Weng, Aoqi Gao, Gaojie Song, Mingyao Liu, Qiong Xie, Yonghui Wang, Weiqiang Lu
مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Biotechnology, Evolutionary Biology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, tumor microenvironment exerts, suppress tumor growth, tuning structural modification, 7aj b, 7ai b, 2b sub, 2a sub, position produced potent, 2 ‑ aminopyrimidine, obtaining novel dual, 4 -/ 5, r dual antagonism, novel 2, position 4, indole modification, aminopyrimidine compounds, novel class, work provided, systemic assessment, substituting indole, r antagonists, r antagonism