المؤلفون: Yi Zhang, Roslyn Tedja, Michael Millman, Terrence Wong, Alexandra Fox, Hussein Chehade, Meyer Gershater, Nicholas Adzibolosu, Radhika Gogoi, Matthew Anderson, Thomas Rutherford, Zhenggang Zhang, Michael Chopp, Gil Mor, Ayesha B. Alvero

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Pharmacology, Immunology, Cancer, Chemical Sciences not elsewhere classified, specific signaling pathway, promotes metastatic potential, polycomb repressor complex, loss accelerated formation, induce epigenetic change, human omental explants, enhance migratory potential, drive disease progression, targeting exosomal mir, drove tumor progression, derived exosomal mir, ovarian cancer cells, potent epigenetic regulator, ovarian tumor microenvironment, 421 targets cbx7, tumor suppressor, identified mir, oc cells, novel regulator, important regulator, adipose microenvironment

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Adipose-derived_exosomal_miR-421_targets_CBX7_and_promotes_metastatic_potential_in_ovarian_cancer_cells/24709018

الاتاحة: https://doi.org/10.6084/m9.figshare.24709018.v1
https://figshare.com/articles/journal_contribution/Additional_file_1_of_Adipose-derived_exosomal_miR-421_targets_CBX7_and_promotes_metastatic_potential_in_ovarian_cancer_cells/24709018

المؤلفون: Alexandra Van Hall-Beauvais, Jesse R Poganik, Kuan-Ting Huang, Saba Parvez, Yi Zhao, Hong-Yu Lin, Xuyu Liu, Marcus John Curtis Long, Yimon Aye

المصدر: eLife, Vol 11 (2022)

مصطلحات موضوعية: Keap1/Nrf2 antioxidant response, electrophile signaling, paralog-specific signaling, zebrafish, REX technologies, covalent drug mode-of-action, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/83373; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/eda320ac548e43cfb8ab7eb2372f9c20

المؤلفون: Arini Isnani Preninka (14253342), Karen Kuriya (14253345), Kyosuke Yazawa (14253348), Michiko Yoshii (14253351), Yuhki Yanase (3960317), Ralf Jockers (245630), Julie Dam (8208489), Toru Hosoi (154313), Koichiro Ozawa (154324)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Molecular Biology, Neuroscience, Physiology, Immunology, Science Policy, Mental Health, Virology, Computational Biology, Cardiology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, stress response gene, present study examined, affect early events, r bret biosensor, leptin resistance observed, endoplasmic reticulum stress, specific signaling pathways, leptin receptor ob, endoplasmic reticulum, r receptor, leptin signaling, r oligomerization, leptin pathway, unlike methionine, significantly inhibited, signal transducer

Relation: https://figshare.com/articles/journal_contribution/S1_Raw_images_-/21718563

الاتاحة: https://doi.org/10.1371/journal.pone.0278965.s001

المؤلفون: Xiaoying Liu (192486), Sarah A. Taylor (9955073), Kyle D. Gromer (9955082), Danny Zhang (11949417), Susan C. Hubchak (11949420), Brian E. LeCuyer (11949423), Takao Iwawaki (113994), Zengdun Shi (477771), Don C. Rockey (7466182), Richard M. Green (9955091)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, simple hepatic steatosis, lack hepatocyte x, high fat sugar, endoplasmic reticulum stress, hepatic stellate cells, upr protein x, cell signaling pathways, stage liver disease, liver cell, immune cells, upr signaling, specific signaling, signaling pathway, united states, previously shown, nonalcoholic steatohepatitis, nash ), mice lacking, liver transplantation, liver injury

Relation: https://figshare.com/articles/journal_contribution/Raw_images_of_all_the_blots_/18427995

الاتاحة: https://doi.org/10.1371/journal.pone.0261789.s005

المؤلفون: Xiaoying Liu (192486), Sarah A. Taylor (9955073), Kyle D. Gromer (9955082), Danny Zhang (11949417), Susan C. Hubchak (11949420), Brian E. LeCuyer (11949423), Takao Iwawaki (113994), Zengdun Shi (477771), Don C. Rockey (7466182), Richard M. Green (9955091)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, simple hepatic steatosis, lack hepatocyte x, high fat sugar, endoplasmic reticulum stress, hepatic stellate cells, upr protein x, cell signaling pathways, stage liver disease, liver cell, immune cells, upr signaling, specific signaling, signaling pathway, united states, previously shown, nonalcoholic steatohepatitis, nash ), mice lacking, liver transplantation, liver injury

Relation: https://figshare.com/articles/journal_contribution/Antibodies_used_in_western_blotting_/18428001

الاتاحة: https://doi.org/10.1371/journal.pone.0261789.s006

المؤلفون: Xiaoying Liu (192486), Sarah A. Taylor (9955073), Kyle D. Gromer (9955082), Danny Zhang (11949417), Susan C. Hubchak (11949420), Brian E. LeCuyer (11949423), Takao Iwawaki (113994), Zengdun Shi (477771), Don C. Rockey (7466182), Richard M. Green (9955091)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, simple hepatic steatosis, lack hepatocyte x, high fat sugar, endoplasmic reticulum stress, hepatic stellate cells, upr protein x, cell signaling pathways, stage liver disease, liver cell, immune cells, upr signaling, specific signaling, signaling pathway, united states, previously shown, nonalcoholic steatohepatitis, nash ), mice lacking, liver transplantation, liver injury

Relation: https://figshare.com/articles/journal_contribution/Antibodies_used_in_flow_cytometry_/18428004

الاتاحة: https://doi.org/10.1371/journal.pone.0261789.s007

المؤلفون: Mingyuan Chen (4484704), Tengqian Sun (11791227), Yanghao Zhong (11791230), Xin Zhou (54275), Jin Zhang (53297)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Cancer, Infectious Diseases, Plant Biology, Biological Sciences not elsewhere classified, Physical Sciences not elsewhere classified, underlying regulatory mechanisms, resolution expansion microscopy, rapamycin complex 1, lipid second messengers, highly sensitive excitation, aktar2 ), enabling, specific spatial organization, multifaceted kinase akt, akt activity dynamics, growth factor stimulation, lysosomal akt activity, kinase activity, akt activity, specific signaling, lysosomal surface, lysosomal membrane, wide range, targeted depletion

Relation: https://figshare.com/articles/journal_contribution/A_Highly_Sensitive_Fluorescent_Akt_Biosensor_Reveals_Lysosome-Selective_Regulation_of_Lipid_Second_Messengers_and_Kinase_Activity/17124336

الاتاحة: https://doi.org/10.1021/acscentsci.1c00919.s001

المؤلفون: Kravchenko-Balasha, Nataly, author

المصدر: Advances in Info-Metrics : Information and Information Processing across Disciplines, 2020, ill.

الاتاحة: https://doi.org/10.1093/oso/9780190636685.003.0008

المؤلفون: V. I. Shynkevych, I. P. Kaidashev

المصدر: Zaporožskij Medicinskij Žurnal, Vol 21, Iss 1, Pp 137-143 (2019)

مصطلحات موضوعية: I. P. Kaidashev Abstract The role of macrophages in chronic periodontitis (CP) is essential, but not well understood. The purpose was a thematic analysis of the literature on contribution of M1/M2 macrophage subpopulations to the pathogenesis of chronic periodontitis, and methodology for macrophages study in order to define directions and approaches for further investigations. Our own research findings as well as papers for the topic by searching the electronic databases (the Google Scholar, PMC, PubMed) were analyzed. M1 macrophages can contribute to CP exacerbation, systemic inflammation enhancement, destruction of periodontal ligament, and inhibition of osteoclastogenesis. M2 macrophages are able both to develop tolerance influenced by LPS of periodontopathogens, and to enhance proinflammatory abilities. Experimental depletion of macrophages using clodronate liposomes can prevent the bone resorption. Influences on M1/M2 in CP with the purpose of treatment are not adequately investigated. Polarization of macrophages is regulated by a wide spectrum of recognizing receptors, cytokines, specific signaling pathways and genetic programs, some of which are used as phenotype markers of certain macrophages. The unique molecules for M1/M2 are absent. Phenotypic markers of M1 and M2 show overlap, so markers combinations are used depending on a purpose and type of macrophages or profile/combination of expressed genes. The article lists markers used in various studies for M1/M2 identification. Conclusions. Most of the data on the role of M1/M2 in CP was obtained using monocyte-derived macrophages in vitro and in animal models. This paper highlights the important role of M1 and M2 subpopulations of macrophages in the pathogenesis of CP in humans. The identification of predominant macrophage phenotypes remains elusive, as well as consequences of influences on them. Immunohistochemical methods are indispensable for human studies at the present stage due to availability of biops, chronic periodontitis, macrophages, Medicine

وصف الملف: electronic resource

Relation: http://zmj.zsmu.edu.ua/article/view/155863/155881; https://doaj.org/toc/2306-4145; https://doaj.org/toc/2310-1210

URL الوصول: https://doaj.org/article/9a4e19c408a848c49603fe4190aa5596

المؤلفون: Huiqing Hu, Yasuhiro Kurasawa, Qing Zhou, Ziyin Li

مصطلحات موضوعية: Biophysics, Microbiology, Cell Biology, Genetics, Physiology, Developmental Biology, Cancer, Hematology, Physical Sciences not elsewhere classified, specific signaling pathways, providing mechanistic insights, multiple cytoskeletal structures, early branching eukaryote, div >< p, biochemical assays demonstrate, 13 family protein, longitudinal cell axis, cell division plane, cell anterior toward, 5 causes loss, 5 bundles microtubules, promoting microtubule bundling, cytokinesis regulatory pathway, 13 family kinesin, posterior cell tip, trypanosoma brucei <, microtubule bundling, cell posterior, flagellated cell, brucei <

Relation: https://figshare.com/articles/figure/Co-immunoprecipitation_of_KIN13-5_and_CIF1_and_structural_comparison_between_KIN13-5_and_kinesin-13_family_proteins_from_other_organisms_/25129942

الاتاحة: https://doi.org/10.1371/journal.ppat.1012000.s001
https://figshare.com/articles/figure/Co-immunoprecipitation_of_KIN13-5_and_CIF1_and_structural_comparison_between_KIN13-5_and_kinesin-13_family_proteins_from_other_organisms_/25129942

المؤلفون: Huiqing Hu, Yasuhiro Kurasawa, Qing Zhou, Ziyin Li

مصطلحات موضوعية: Biophysics, Microbiology, Cell Biology, Genetics, Physiology, Developmental Biology, Cancer, Hematology, Physical Sciences not elsewhere classified, specific signaling pathways, providing mechanistic insights, multiple cytoskeletal structures, early branching eukaryote, div >< p, biochemical assays demonstrate, 13 family protein, longitudinal cell axis, cell division plane, cell anterior toward, 5 causes loss, 5 bundles microtubules, promoting microtubule bundling, cytokinesis regulatory pathway, 13 family kinesin, posterior cell tip, trypanosoma brucei <, microtubule bundling, cell posterior, flagellated cell, brucei <

Relation: https://figshare.com/articles/dataset/Excel_spreadsheet_containing_in_separate_sheets_the_underlying_numerical_data_for_Figs_1A_2B_2C_2F_2G_2H_2I_3C_3D_4B_and_8B_/25129945

الاتاحة: https://doi.org/10.1371/journal.ppat.1012000.s002
https://figshare.com/articles/dataset/Excel_spreadsheet_containing_in_separate_sheets_the_underlying_numerical_data_for_Figs_1A_2B_2C_2F_2G_2H_2I_3C_3D_4B_and_8B_/25129945

المؤلفون: Huiqing Hu, Yasuhiro Kurasawa, Qing Zhou, Ziyin Li

مصطلحات موضوعية: Biophysics, Microbiology, Cell Biology, Genetics, Physiology, Developmental Biology, Cancer, Hematology, Physical Sciences not elsewhere classified, specific signaling pathways, providing mechanistic insights, multiple cytoskeletal structures, early branching eukaryote, div >< p, biochemical assays demonstrate, 13 family protein, longitudinal cell axis, cell division plane, cell anterior toward, 5 causes loss, 5 bundles microtubules, promoting microtubule bundling, cytokinesis regulatory pathway, 13 family kinesin, posterior cell tip, trypanosoma brucei <, microtubule bundling, cell posterior, flagellated cell, brucei <

Relation: https://figshare.com/articles/figure/Identification_of_KIN13-5_as_an_interacting_partner_of_FPRC_and_determination_of_its_subcellular_localization_/25129948

الاتاحة: https://doi.org/10.1371/journal.ppat.1012000.g001
https://figshare.com/articles/figure/Identification_of_KIN13-5_as_an_interacting_partner_of_FPRC_and_determination_of_its_subcellular_localization_/25129948

المؤلفون: Huiqing Hu, Yasuhiro Kurasawa, Qing Zhou, Ziyin Li

مصطلحات موضوعية: Biophysics, Microbiology, Cell Biology, Genetics, Physiology, Developmental Biology, Cancer, Hematology, Physical Sciences not elsewhere classified, specific signaling pathways, providing mechanistic insights, multiple cytoskeletal structures, early branching eukaryote, div >< p, biochemical assays demonstrate, 13 family protein, longitudinal cell axis, cell division plane, cell anterior toward, 5 causes loss, 5 bundles microtubules, promoting microtubule bundling, cytokinesis regulatory pathway, 13 family kinesin, posterior cell tip, trypanosoma brucei <, microtubule bundling, cell posterior, flagellated cell, brucei <

Relation: https://figshare.com/articles/figure/Depletion_of_KIN13-5_by_RNAi_in_procyclic_trypanosomes_caused_cytokinesis_defects_/25129951

الاتاحة: https://doi.org/10.1371/journal.ppat.1012000.g002
https://figshare.com/articles/figure/Depletion_of_KIN13-5_by_RNAi_in_procyclic_trypanosomes_caused_cytokinesis_defects_/25129951

المؤلفون: Huiqing Hu, Yasuhiro Kurasawa, Qing Zhou, Ziyin Li

مصطلحات موضوعية: Biophysics, Microbiology, Cell Biology, Genetics, Physiology, Developmental Biology, Cancer, Hematology, Physical Sciences not elsewhere classified, specific signaling pathways, providing mechanistic insights, multiple cytoskeletal structures, early branching eukaryote, div >< p, biochemical assays demonstrate, 13 family protein, longitudinal cell axis, cell division plane, cell anterior toward, 5 causes loss, 5 bundles microtubules, promoting microtubule bundling, cytokinesis regulatory pathway, 13 family kinesin, posterior cell tip, trypanosoma brucei <, microtubule bundling, cell posterior, flagellated cell, brucei <

Relation: https://figshare.com/articles/figure/Knockdown_of_KIN13-5_causes_mis-placement_of_the_cell_division_plane_/25129954

الاتاحة: https://doi.org/10.1371/journal.ppat.1012000.g003
https://figshare.com/articles/figure/Knockdown_of_KIN13-5_causes_mis-placement_of_the_cell_division_plane_/25129954

المؤلفون: Huiqing Hu, Yasuhiro Kurasawa, Qing Zhou, Ziyin Li

مصطلحات موضوعية: Biophysics, Microbiology, Cell Biology, Genetics, Physiology, Developmental Biology, Cancer, Hematology, Physical Sciences not elsewhere classified, specific signaling pathways, providing mechanistic insights, multiple cytoskeletal structures, early branching eukaryote, div >< p, biochemical assays demonstrate, 13 family protein, longitudinal cell axis, cell division plane, cell anterior toward, 5 causes loss, 5 bundles microtubules, promoting microtubule bundling, cytokinesis regulatory pathway, 13 family kinesin, posterior cell tip, trypanosoma brucei <, microtubule bundling, cell posterior, flagellated cell, brucei <

Relation: https://figshare.com/articles/figure/Depletion_of_KIN13-5_by_RNAi_inhibits_microtubule_bundling_at_the_posterior_of_the_NFD_cell_and_the_nascent_posterior_of_the_OFD_cell_/25129960

الاتاحة: https://doi.org/10.1371/journal.ppat.1012000.g005
https://figshare.com/articles/figure/Depletion_of_KIN13-5_by_RNAi_inhibits_microtubule_bundling_at_the_posterior_of_the_NFD_cell_and_the_nascent_posterior_of_the_OFD_cell_/25129960

المؤلفون: Huiqing Hu, Yasuhiro Kurasawa, Qing Zhou, Ziyin Li

مصطلحات موضوعية: Biophysics, Microbiology, Cell Biology, Genetics, Physiology, Developmental Biology, Cancer, Hematology, Physical Sciences not elsewhere classified, specific signaling pathways, providing mechanistic insights, multiple cytoskeletal structures, early branching eukaryote, div >< p, biochemical assays demonstrate, 13 family protein, longitudinal cell axis, cell division plane, cell anterior toward, 5 causes loss, 5 bundles microtubules, promoting microtubule bundling, cytokinesis regulatory pathway, 13 family kinesin, posterior cell tip, trypanosoma brucei <, microtubule bundling, cell posterior, flagellated cell, brucei <

Relation: https://figshare.com/articles/figure/KIN13-5_forms_a_multimer_on_blue_native_gels_/25129963

الاتاحة: https://doi.org/10.1371/journal.ppat.1012000.g006
https://figshare.com/articles/figure/KIN13-5_forms_a_multimer_on_blue_native_gels_/25129963

المؤلفون: Huiqing Hu, Yasuhiro Kurasawa, Qing Zhou, Ziyin Li

مصطلحات موضوعية: Biophysics, Microbiology, Cell Biology, Genetics, Physiology, Developmental Biology, Cancer, Hematology, Physical Sciences not elsewhere classified, specific signaling pathways, providing mechanistic insights, multiple cytoskeletal structures, early branching eukaryote, div >< p, biochemical assays demonstrate, 13 family protein, longitudinal cell axis, cell division plane, cell anterior toward, 5 causes loss, 5 bundles microtubules, promoting microtubule bundling, cytokinesis regulatory pathway, 13 family kinesin, posterior cell tip, trypanosoma brucei <, microtubule bundling, cell posterior, flagellated cell, brucei <

Relation: https://figshare.com/articles/figure/KIN13-5_functions_downstream_of_FPRC_in_the_cytokinesis_regulatory_pathway_/25129969

الاتاحة: https://doi.org/10.1371/journal.ppat.1012000.g008
https://figshare.com/articles/figure/KIN13-5_functions_downstream_of_FPRC_in_the_cytokinesis_regulatory_pathway_/25129969

المؤلفون: Huiqing Hu, Yasuhiro Kurasawa, Qing Zhou, Ziyin Li

مصطلحات موضوعية: Biophysics, Microbiology, Cell Biology, Genetics, Physiology, Developmental Biology, Cancer, Hematology, Physical Sciences not elsewhere classified, specific signaling pathways, providing mechanistic insights, multiple cytoskeletal structures, early branching eukaryote, div >< p, biochemical assays demonstrate, 13 family protein, longitudinal cell axis, cell division plane, cell anterior toward, 5 causes loss, 5 bundles microtubules, promoting microtubule bundling, cytokinesis regulatory pathway, 13 family kinesin, posterior cell tip, trypanosoma brucei <, microtubule bundling, cell posterior, flagellated cell, brucei <

Relation: https://figshare.com/articles/figure/KIN13-5_bundles_microtubules_i_in_vitro_i_/25129966

الاتاحة: https://doi.org/10.1371/journal.ppat.1012000.g007
https://figshare.com/articles/figure/KIN13-5_bundles_microtubules_i_in_vitro_i_/25129966

المؤلفون: Huiqing Hu, Yasuhiro Kurasawa, Qing Zhou, Ziyin Li

مصطلحات موضوعية: Biophysics, Microbiology, Cell Biology, Genetics, Physiology, Developmental Biology, Cancer, Hematology, Physical Sciences not elsewhere classified, specific signaling pathways, providing mechanistic insights, multiple cytoskeletal structures, early branching eukaryote, div >< p, biochemical assays demonstrate, 13 family protein, longitudinal cell axis, cell division plane, cell anterior toward, 5 causes loss, 5 bundles microtubules, promoting microtubule bundling, cytokinesis regulatory pathway, 13 family kinesin, posterior cell tip, trypanosoma brucei <, microtubule bundling, cell posterior, flagellated cell, brucei <

Relation: https://figshare.com/articles/figure/KIN13-5_knockdown_impairs_posterior_cytoskeleton_morphogenesis_/25129957

الاتاحة: https://doi.org/10.1371/journal.ppat.1012000.g004
https://figshare.com/articles/figure/KIN13-5_knockdown_impairs_posterior_cytoskeleton_morphogenesis_/25129957

المؤلفون: Couée, Ivan

المساهمون: Ecosystèmes, biodiversité, évolution Rennes (ECOBIO), Université de Rennes (UR)-Institut Ecologie et Environnement - CNRS Ecologie et Environnement (INEE-CNRS), Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS)-Observatoire des Sciences de l'Univers de Rennes (OSUR), Université de Rennes (UR)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de Rennes 2 (UR2)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Centre National de la Recherche Scientifique (CNRS), Couée I.

المصدر: Plant Abiotic Stress Signaling. Methods in Molecular Biology ; https://hal.science/hal-04061048 ; Couée I. Plant Abiotic Stress Signaling. Methods in Molecular Biology, 2642, Humana, pp.429-444, 2023, ⟨10.1007/978-1-0716-3044-0_23⟩

مصطلحات موضوعية: Cell-specific signaling, Climate change, Modeling, Multiple stress, Plant stress responses, Plant stress tolerance, Signal transduction, Stress memory, Stress sensing, [SDE.BE]Environmental Sciences/Biodiversity and Ecology

Relation: info:eu-repo/semantics/altIdentifier/pmid/36944892; PUBMED: 36944892

الاتاحة: https://hal.science/hal-04061048
https://doi.org/10.1007/978-1-0716-3044-0_23