المؤلفون: Takumi Nakao, Kosuke Kosai, Norihiko Akamatsu, Kenji Ota, Fujiko Mitsumoto-Kaseida, Hiroo Hasegawa, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara

المصدر: Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)

مصطلحات موضوعية: macrolide resistance, solithromycin, lascufloxacin, capsular type, sequence type, QRDR, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2024.1391879/full; https://doaj.org/toc/2235-2988

URL الوصول: https://doaj.org/article/cd17f38933654030a305e7d1f9ca4157

المؤلفون: Melinta Therapeutics, Inc.

المصدر: A Single-center, Double-blind, Randomised, Placebo-controlled Crossover Study to Evaluate the Effect of Solithromycin on Airway Inflammation in Male and Female Patients With Chronic Obstructive Pulmonary Disease

المؤلفون: Yasuhiro Kimura, Masahiro Shinoda, Masaharu Shinkai, Takeshi Kaneko

المصدر: PeerJ, Vol 11, p e14695 (2023)

مصطلحات موضوعية: Solithromycin, Goblet cell, SAM pointed domain containing ETS transcription factor, Chloride channel accessory 1, Mucin, MUC5AC, Medicine, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://peerj.com/articles/14695.pdf; https://peerj.com/articles/14695/; https://doaj.org/toc/2167-8359

URL الوصول: https://doaj.org/article/05dc7e0fc828486c873cd93c9528e73a

المصدر: Phase 1 Open Label Trial of the Safety, Tolerability, and Genitourinary and Pharyngeal Pharmacokinetics of Solithromycin

المؤلفون: Biomedical Advanced Research and Development Authority

المصدر: A Phase 2/3, Randomized, Open-Label, Multi-center Study to Determine the Safety and Efficacy of Solithromycin in Adolescents and Children With Suspected or Confirmed Community-Acquired Bacterial Pneumonia

المؤلفون: National Institute of Allergy and Infectious Diseases (NIAID)

المصدر: An Open-Label, Randomized, Multi-Center Study to Evaluate the Efficacy and Safety of a Single Dose of Oral Solithromycin Compared to Single-Dose Intramuscular Ceftriaxone Plus Single-Dose Oral Azithromycin in the Treatment of Male and Female Patients With Uncomplicated Urogenital Gonorrhea With or Without Concomitant Chlamydia
Chen MY, McNulty A, Avery A, Whiley D, Tabrizi SN, Hardy D, Das AF, Nenninger A, Fairley CK, Hocking JS, Bradshaw CS, Donovan B, Howden BP, Oldach D; Solitaire-U Team. Solithromycin versus ceftriaxone plus azithromycin for the treatment of uncomplicated genital gonorrhoea (SOLITAIRE-U): a randomised phase 3 non-inferiority trial. Lancet Infect Dis. 2019 Aug;19(8):833-842. doi: 10.1016/S1473-3099(19)30116-1. Epub 2019 Jun 10.

المؤلفون: Department of Health and Human Services

المصدر: A Phase 1, Open-label, Multi-center Study to Determine the Pharmacokinetics and Safety of Solithromycin as Add-on Therapy in Adolescents and Children With Suspected or Confirmed Bacterial Infection
Beechinor RJ, Cohen-Wolkowiez M, Jasion T, Hornik CP, Lang JE, Hernandez R, Gonzalez D. A Dried Blood Spot Analysis for Solithromycin in Adolescents, Children, and Infants: A Short Communication. Ther Drug Monit. 2019 Dec;41(6):761-765. doi: 10.1097/FTD.0000000000000670.
Gonzalez D, James LP, Al-Uzri A, Bosheva M, Adler-Shohet FC, Mendley SR, Bradley JS, Espinosa C, Tsonkova E, Moffett K, Marquez L, Simonsen KA, Stoilov S, Boakye-Agyeman F, Jasion T, Hornik CP, Hernandez R, Benjamin DK Jr, Cohen-Wolkowiez M. Population Pharmacokinetics and Safety of Solithromycin following Intravenous and Oral Administration in Infants, Children, and Adolescents. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00692-18. doi: 10.1128/AAC.00692-18. Print 2018 Aug.

المصدر: An Open Label, Proof of Principle Study to Evaluate the Efficacy and Safety of Solithromycin for the Treatment of Nonalcoholic Steatohepatitis Without Cirrhosis

المصدر: A Randomized, Double-Blind, Multi-Center Study to Evaluate the Efficacy and Safety of Intravenous to Oral Solithromycin (CEM-101) Compared to Intravenous to Oral Moxifloxacin in the Treatment of Adult Patients With Community-Acquired Bacterial Pneumonia
File TM Jr, Rewerska B, Vucinic-Mihailovic V, Gonong JRV, Das AF, Keedy K, Taylor D, Sheets A, Fernandes P, Oldach D, Jamieson BD. SOLITAIRE-IV: A Randomized, Double-Blind, Multicenter Study Comparing the Efficacy and Safety of Intravenous-to-Oral Solithromycin to Intravenous-to-Oral Moxifloxacin for Treatment of Community-Acquired Bacterial Pneumonia. Clin Infect Dis. 2016 Oct 15;63(8):1007-1016. doi: 10.1093/cid/ciw490. Epub 2016 Jul 22.

المصدر: An Open-Label Study to Evaluate the Efficacy and Safety of a Single-Dose of Oral CEM-101 in the Treatment of Male and Female Patients With Uncomplicated Urogenital Gonorrhea
Hook EW 3rd, Golden M, Jamieson BD, Dixon PB, Harbison HS, Lowens S, Fernandes P. A Phase 2 Trial of Oral Solithromycin 1200 mg or 1000 mg as Single-Dose Oral Therapy for Uncomplicated Gonorrhea. Clin Infect Dis. 2015 Oct 1;61(7):1043-8. doi: 10.1093/cid/civ478. Epub 2015 Jun 18.

المصدر: A Randomized, Double-Blind, Multi-Center Study to Evaluate the Efficacy and Safety of Oral Solithromycin (CEM-101) Compared to Oral Moxifloxacin in the Treatment of Adult Patients With Community-Acquired Bacterial Pneumonia
Barrera CM, Mykietiuk A, Metev H, Nitu MF, Karimjee N, Doreski PA, Mitha I, Tanaseanu CM, Molina JM, Antonovsky Y, Van Rensburg DJ, Rowe BH, Flores-Figueroa J, Rewerska B, Clark K, Keedy K, Sheets A, Scott D, Horwith G, Das AF, Jamieson B, Fernandes P, Oldach D; SOLITAIRE-ORAL Pneumonia Team. Efficacy and safety of oral solithromycin versus oral moxifloxacin for treatment of community-acquired bacterial pneumonia: a global, double-blind, multicentre, randomised, active-controlled, non-inferiority trial (SOLITAIRE-ORAL). Lancet Infect Dis. 2016 Apr;16(4):421-30. doi: 10.1016/S1473-3099(16)00017-7. Epub 2016 Feb 5.

المصدر: A Randomized, Double-Blind, Multi-Center Study to Evaluate the Efficacy and Safety of Oral CEM-101 Compared to Oral Levofloxacin in the Treatment of Patients With Community-Acquired Bacterial Pneumonia
Oldach D, Clark K, Schranz J, Das A, Craft JC, Scott D, Jamieson BD, Fernandes P. Randomized, double-blind, multicenter phase 2 study comparing the efficacy and safety of oral solithromycin (CEM-101) to those of oral levofloxacin in the treatment of patients with community-acquired bacterial pneumonia. Antimicrob Agents Chemother. 2013 Jun;57(6):2526-34. doi: 10.1128/AAC.00197-13. Epub 2013 Mar 18.

المؤلفون: Department of Health and Human Services

المصدر: A Phase 1, Open-label, Multi-center Study to Determine the PK and Safety of Solithromycin as Add-on Therapy in Adolescents With Suspected or Confirmed Bacterial Infection
Beechinor RJ, Cohen-Wolkowiez M, Jasion T, Hornik CP, Lang JE, Hernandez R, Gonzalez D. A Dried Blood Spot Analysis for Solithromycin in Adolescents, Children, and Infants: A Short Communication. Ther Drug Monit. 2019 Dec;41(6):761-765. doi: 10.1097/FTD.0000000000000670.
Gonzalez D, James LP, Al-Uzri A, Bosheva M, Adler-Shohet FC, Mendley SR, Bradley JS, Espinosa C, Tsonkova E, Moffett K, Marquez L, Simonsen KA, Stoilov S, Boakye-Agyeman F, Jasion T, Hornik CP, Hernandez R, Benjamin DK Jr, Cohen-Wolkowiez M. Population Pharmacokinetics and Safety of Solithromycin following Intravenous and Oral Administration in Infants, Children, and Adolescents. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00692-18. doi: 10.1128/AAC.00692-18. Print 2018 Aug.
Gonzalez D, Palazzi DL, Bhattacharya-Mithal L, Al-Uzri A, James LP, Bradley J, Neu N, Jasion T, Hornik CP, Smith PB, Benjamin DK Jr, Keedy K, Fernandes P, Cohen-Wolkowiez M. Solithromycin Pharmacokinetics in Plasma and Dried Blood Spots and Safety in Adolescents. Antimicrob Agents Chemother. 2016 Mar 25;60(4):2572-6. doi: 10.1128/AAC.02561-15. Print 2016 Apr.

المؤلفون: Muhammad Habiburrahman, Vivian Soetikno, Wani Riselia Sirait, Missy Savira

المصدر: Indonesian Journal of Pharmacy, Pp 335–353-335–353 (2020)

مصطلحات موضوعية: antibiotic, cem-101, gonorrhea, solithromycin, resistance, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://jurnal.ugm.ac.id/v3/IJP/article/view/1123; https://doaj.org/toc/2338-9427; https://doaj.org/toc/2338-9486

URL الوصول: https://doaj.org/article/cbae30110717402d9df5f0d7e0a579cb

المؤلفون: Weiming Yao, Guangjian Xu, Duoyun Li, Bing Bai, Hongyan Wang, Hang Cheng, Jinxin Zheng, Xiang Sun, Zhiwei Lin, Qiwen Deng, Zhijian Yu

المصدر: BMC Infectious Diseases, Vol 19, Iss 1, Pp 1-8 (2019)

مصطلحات موضوعية: Staphylococcus aureus, Constitutive macrolide-lincosamide-streptogramin B (cMLSB) resistance, Solithromycin, Infectious and parasitic diseases, RC109-216

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12879-019-3779-8; https://doaj.org/toc/1471-2334

URL الوصول: https://doaj.org/article/1fe277985b2542cc81c0b0dd264ad0da

المؤلفون: Nakao, Takumi, Kosai, Kosuke, Akamatsu, Norihiko, Ota, Kenji, Mitsumoto-Kaseida, Fujiko, Hasegawa, Hiroo, Izumikawa, Koichi, Mukae, Hiroshi, Yanagihara, Katsunori

مصطلحات موضوعية: macrolide resistance, solithromycin, lascufloxacin, capsular type, sequence type, QRDR

وصف الملف: application/pdf

Relation: Frontiers in Cellular and Infection Microbiology; 14; art. no. 1391879; https://nagasaki-u.repo.nii.ac.jp/record/2001274/files/FCIM14_1391879.pdf

الاتاحة: https://nagasaki-u.repo.nii.ac.jp/record/2001274/files/FCIM14_1391879.pdf

المؤلفون: Takumi Nakao, Kosuke Kosai, Norihiko Akamatsu, Kenji Ota, Fujiko Mitsumoto-Kaseida, Hiroo Hasegawa, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara

مصطلحات موضوعية: Clinical Microbiology, Medical Bacteriology, Medical Infection Agents (incl. Prions), Medical Virology, macrolide resistance, solithromycin, lascufloxacin, capsular type, sequence type, QRDR

Relation: https://figshare.com/articles/dataset/Table_1_Molecular_and_phenotypic_characterization_of_Streptococcus_pneumoniae_isolates_in_a_Japanese_tertiary_care_hospital_docx/26347030

الاتاحة: https://doi.org/10.3389/fcimb.2024.1391879.s001
https://figshare.com/articles/dataset/Table_1_Molecular_and_phenotypic_characterization_of_Streptococcus_pneumoniae_isolates_in_a_Japanese_tertiary_care_hospital_docx/26347030

المؤلفون: Svetlov, Maxim S., Vázquez-Laslop, Nora, Mankin, Alexander S.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2017 Dec . 114(52), 13673-13678.

URL الوصول: https://www.jstor.org/stable/26488759

المؤلفون: Donald BJ, Surani S, Deol HS, Mbadugha UJ, Udeani G

المصدر: Drug Design, Development and Therapy, Vol Volume 11, Pp 3559-3566 (2017)

مصطلحات موضوعية: solithromycin, macrolide antibiotics, community-acquired bacterial pneumonia, CABP, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.dovepress.com/spotlight-on-solithromycin-in-the-treatment-of-community-acquired-bact-peer-reviewed-article-DDDT; https://doaj.org/toc/1177-8881

URL الوصول: https://doaj.org/article/1302bc8a908f460d8200d3878c9f6673

المؤلفون: Takahiro Maruyama, Shinya Uehara, Koichi Hatano, Junko Sato, Ryoichi Hamasuna, Satoshi Uno, Hiroshi Kiyota, Kiyohito Ishikawa, Shingo Yamamoto, Yoshiki Hiyama, Motoshi Kawahara, Kanao Kobayashi, Keijiro Kiyoshima, Jun Miyazaki, Masaru Matumura, Toru Sumii, Hideo Hirayama, Kazushi Tanaka, Kazumasa Matsumoto, Kenji Hayashi, Shuichi Kawai, Naoya Masumori, Koichi Monden, Shin Ito, Kenji Ito, Yoshikazu Togo, Katsumi Shigemura, Masanobu Izumitani, Masayasu Ito, Hiroshi Yotsuyanagi, Takahide Hosobe, Yutaka Shiono, Kazuo Takayama, Hideaki Hanaki, Mitsuru Yasuda, Mutsumasa Yoh, Hiroshi Hayami, Hideari Ihara, Teruhiko Yokoyama, Hirofumi Nishimura, Tetsuya Matsumoto, Hiroki Yamada, Motonori Kano, Kazuhiro Tateda, Shin Egawa, Masahiro Matsumoto, Hitoshi Kadena, Shinichi Kaji, Hiroyuki Kitano, Ryuji Fujita, Takanori Tojo, Koichiro Wada, Satoshi Takahashi

المصدر: Journal of Infection and Chemotherapy. 28:1-5

مصطلحات موضوعية: Male, Microbiology (medical), Sitafloxacin, medicine.medical_specialty, Solithromycin, Erythromycin, Chlamydia trachomatis, Microbial Sensitivity Tests, Azithromycin, medicine.disease_cause, Tosufloxacin, Japan, Levofloxacin, Internal medicine, Drug Resistance, Bacterial, medicine, Humans, Pharmacology (medical), Urethritis, business.industry, medicine.disease, Anti-Bacterial Agents, Infectious Diseases, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59d0af8e790717eb21748359f07ccd7a
https://doi.org/10.1016/j.jiac.2021.09.012