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1Academic Journal
المؤلفون: Nasa Sakamoto, Kenichi Miyata, Toshiro Fukami
مصطلحات موضوعية: Pharmacology, Biotechnology, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, percent dissolution differed, mechanistic differences underlying, orally administered quabodepistat, small intestine compared, improve oral bioavailability, dynamic ph change, code name opc, shift dissolution studies, 2hba demonstrated supersaturation, two cocrystals quabodepistat, small intestine, dissolution studies, mechanistic analysis, dissolution method, demonstrate supersaturation, bioavailability studies, study aimed, poor solubility, performed ph, larger quantity, hydroxybenzoic acid, free form, fold greater, discover cocrystals
الاتاحة: https://doi.org/10.1021/acs.molpharmaceut.3c01059.s001
https://figshare.com/articles/journal_contribution/Quabodepistat_OPC-167832_a_Novel_Antituberculosis_Drug_Candidate_Enhancing_Oral_Bioavailability_via_Cocrystallization_and_Mechanistic_Analysis_of_Bioavailability_in_Two_Cocrystals/24834223