المؤلفون: Nehad S El Salamouni (11831920), Benjamin J. Buckley (2733403), Longguang Jiang (697806), Mingdong Huang (73944), Marie Ranson (25441), Michael J. Kelso (1585372), Haibo Yu (273911)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Pharmacology, Evolutionary Biology, Cancer, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, urokinase plasminogen activator, tumor cell invasion, observed species selectivity, experimental findings reveal, displayed reduced selectivity, mouse species selectivity, thus confounding interpretation, promising antimetastasis target, parent drug amiloride, mouse upa ), selective upa inhibitors, mouse upa inhibitors, 7 , mouse upa, inhibitors derived, thus supporting, antimetastasis drugs, hexamethylene amiloride, amiloride class, water networks

Relation: https://figshare.com/articles/journal_contribution/Disruption_of_Water_Networks_is_the_Cause_of_Human_Mouse_Species_Selectivity_in_Urokinase_Plasminogen_Activator_uPA_Inhibitors_Derived_from_Hexamethylene_Amiloride_HMA_/17192566

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01423.s001

المؤلفون: Nehad S El Salamouni (11831920), Benjamin J. Buckley (2733403), Longguang Jiang (697806), Mingdong Huang (73944), Marie Ranson (25441), Michael J. Kelso (1585372), Haibo Yu (273911)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Pharmacology, Evolutionary Biology, Cancer, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, urokinase plasminogen activator, tumor cell invasion, observed species selectivity, experimental findings reveal, displayed reduced selectivity, mouse species selectivity, thus confounding interpretation, promising antimetastasis target, parent drug amiloride, mouse upa ), selective upa inhibitors, mouse upa inhibitors, 7 , mouse upa, inhibitors derived, thus supporting, antimetastasis drugs, hexamethylene amiloride, amiloride class, water networks

Relation: https://figshare.com/articles/dataset/Disruption_of_Water_Networks_is_the_Cause_of_Human_Mouse_Species_Selectivity_in_Urokinase_Plasminogen_Activator_uPA_Inhibitors_Derived_from_Hexamethylene_Amiloride_HMA_/17192569

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01423.s002