المؤلفون: Liyang Jiang, Na Liu, Fabao Zhao, Boshi Huang, Dongwei Kang, Peng Zhan, Xinyong Liu

المصدر: Acta Pharmaceutica Sinica B, Vol 14, Iss 5, Pp 1987-2005 (2024)

مصطلحات موضوعية: NMDA receptors, GluN2A subtype, Subtype-selective ligands, SARs, Protein ligand interactions, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383524000066; https://doaj.org/toc/2211-3835

URL الوصول: https://doaj.org/article/01198fb708a64a45877e8e846eaff2dd

المؤلفون: Anaëlle Dumazer, Xavier Gómez-Santacana, Fanny Malhaire, Chris Jopling, Damien Maurel, Guillaume Lebon, Amadeu Llebaria, Cyril Goudet

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Ecology, Cancer, Inorganic Chemistry, Chemical Sciences not elsewhere classified, utilizes photosensitive ligands, spatially selective ligands, perform photopharmacological experiments, biomolecules using light, uv light triggers, r photopharmacological tool, prolonged exposure results, potential therapeutic use, 2a , approved antagonist istradefylline, time optical control, uv light, potential use, optical control, r antagonist, light sensitivity, widespread expression, recent years, r throughout, r signaling, photocycloaddition products, neurodegenerative diseases

Relation: https://figshare.com/articles/journal_contribution/Optical_Control_of_Adenosine_A_sub_2A_sub_Receptor_Using_Istradefylline_Photosensitivity/25075347

الاتاحة: https://doi.org/10.1021/acschemneuro.3c00721.s001
https://figshare.com/articles/journal_contribution/Optical_Control_of_Adenosine_A_sub_2A_sub_Receptor_Using_Istradefylline_Photosensitivity/25075347

المؤلفون: Ryan P. McGlynn, Meng Cui, Brittany Brems, Otto Holbrook, Raymond G. Booth

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, ≤ 25 nm, point mutation experiments, high sequence homology, drug discovery purposes, results presented lay, selective ligands using, sat interactions observed, 1f , 1b ,, delineate molecular determinants, 1 , 1b , subtype selective ligands, 5 ‑ ht, 2 ‑ aminotetralin, 1d

Relation: https://figshare.com/articles/journal_contribution/Development_of_2_Aminotetralin-Type_Serotonin_5_HT_sub_1_sub_Agonists_Molecular_Determinants_for_Selective_Binding_and_Signaling_at_5_HT_sub_1A_sub_5_HT_sub_1B_sub_5_HT_sub_1D_sub_and_5_HT_sub_1F_sub_Receptors/24908544

الاتاحة: https://doi.org/10.1021/acschemneuro.3c00658.s001
https://figshare.com/articles/journal_contribution/Development_of_2_Aminotetralin-Type_Serotonin_5_HT_sub_1_sub_Agonists_Molecular_Determinants_for_Selective_Binding_and_Signaling_at_5_HT_sub_1A_sub_5_HT_sub_1B_sub_5_HT_sub_1D_sub_and_5_HT_sub_1F_sub_Receptors/24908544

المؤلفون: Ivan V. Savchenko, Igor D. Zlotnikov, Elena V. Kudryashova

المصدر: Biomimetics, Vol 8, Iss 7, p 543 (2023)

مصطلحات موضوعية: macrophage-mediated therapy, macrophage biomimetics, macrophage-derived particles, selective ligands, Technology

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2313-7673/8/7/543; https://doaj.org/toc/2313-7673

URL الوصول: https://doaj.org/article/7584ba891134440ab4a57b9ac2d924bb

المؤلفون: Gianquinto, Eleonora, Sodano, Federica, Rolando, Barbara, Kostrzewa, Magdalena, Allarà, Marco, Mahmoud, Ali Mokhtar, Kumar, Poulami, Spyrakis, Francesca, Ligresti, Alessia, Chegaev, Konstantin

المساهمون: Gianquinto, Eleonora, Sodano, Federica, Rolando, Barbara, Kostrzewa, Magdalena, Allarà, Marco, Mahmoud, Ali Mokhtar, Kumar, Poulami, Spyrakis, Francesca, Ligresti, Alessia, Chegaev, Konstantin

مصطلحات موضوعية: cannabinoid receptors, hCB2R selective ligands, drug design, in silico simulations, mechanism of receptor activation / deactivation

Relation: volume:27; issue:23; firstpage:8152; lastpage:8176; numberofpages:25; journal:MOLECULES; https://hdl.handle.net/2318/1880431; https://www.mdpi.com/1420-3049/27/23/8152

الاتاحة: https://hdl.handle.net/2318/1880431
https://doi.org/10.3390/molecules27238152
https://www.mdpi.com/1420-3049/27/23/8152

المؤلفون: Lee, Boeun, Taylor, Michelle, Griffin, Suzy A., McInnis, Tamara, Sumien, Nathalie, Mach, Robert H., Luedtke, Robert R.

المصدر: Molecules

مصطلحات موضوعية: D2-like dopamine receptors, D3 dopamine receptor subtype, G-protein coupled receptor (GPCR), bitopic ligands, dopamine receptor subtype selective ligands, Animals, Benzamides / chemistry, Binding, Competitive, Dopamine Agonists / chemistry, Dopamine Antagonists / chemistry, Drug Design, Humans, Kinetics, Levodopa, Ligands, Male, Mice, Inbred DBA, Parkinson Disease / drug therapy, Piperazines / chemistry, Protein Binding, Rats, Receptors, Dopamine D2 / chemistry, Dopamine D3 / chemistry

وصف الملف: application/pdf

Relation: https://doi.org/10.3390/molecules26113182; Lee, B., Taylor, M., Griffin, S. A., McInnis, T., Sumien, N., Mach, R. H., & Luedtke, R. R. (2021). Evaluation of Substituted N-Phenylpiperazine Analogs as D3 vs. D2 Dopamine Receptor Subtype Selective Ligands. Molecules (Basel, Switzerland), 26(11), 3182. https://doi.org/10.3390/molecules26113182; https://hdl.handle.net/20.500.12503/31556; 26; 11

الاتاحة: https://hdl.handle.net/20.500.12503/31556

المؤلفون: Timur A. Mavlyutov, Jing Li, Xinying Liu, Hongtao Shen, Huan Yang, Christopher R. McCurdy, Bikash Pattnaik, Lian-Wang Guo

المصدر: Genes; Volume 13; Issue 12; Pages: 2386

مصطلحات موضوعية: sigma-1 and sigma-2 receptors, selective ligands, photoreceptor protection, AMD-related model, retinal pigment epithelium

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Epigenomics; https://dx.doi.org/10.3390/genes13122386

الاتاحة: https://doi.org/10.3390/genes13122386

المؤلفون: Faundez Parraguez, Manuel, Alarcon Miranda, Carlos, Cho, Young Hwa, Pessoa Mahana, Hernan, Gallardo Garrido, Carlos, Chung, Hery, Faundez, Mario, Pessoa Mahana, David

مصطلحات موضوعية: cannabinoids, 2-pyridone, synthesis, CB2R agonists, ENDOCANNABINOID SYSTEM, SELECTIVE LIGANDS, CB2 RECEPTOR, IDENTIFICATION, HETEROCYCLES, DESIGN, POTENT, DRUGS, 03 Good Health and Well-being, 03 Salud y bienestar

وصف الملف: 15 páginas; application/pdf

Relation: MEDLINE:34681877; https://doi.org/10.3390/ijms222011212; https://repositorio.uc.cl/handle/11534/80023; WOS:000715456600001

الاتاحة: https://repositorio.uc.cl/handle/11534/80023
https://doi.org/10.3390/ijms222011212

المؤلفون: Webling, Kristin, Groves-Chapman, Jessica L., Runesson, Johan, Saar, Indrek, Lang, Andreas, Sillard, Rannar, Jakovenko, Erik, Kofler, Barbara, Holmes, Philip V., Langel, Ülo

المصدر: Neuropeptides. 58:83-92

مصطلحات موضوعية: Galanin, Galanin receptor subtype selective ligands, GAL1R, GAL2R, Label-free real-time technology, XCELLigence, Excitotoxicity, M1154, neurokemi med molekylär neurobiologi, Neurochemistry with Molecular Neurobiology

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-125756
https://doi.org/10.1016/j.npep.2015.12.009

المساهمون: Singh, Waheguru

وصف الملف: Medium: ED; Size: 516 KB

URL الوصول: http://www.osti.gov/scitech/servlets/purl/1048395

المؤلفون: Ariadna Fernández (1638028), José Luis Díaz (1638049), Mónica García (8086490), Sergi Rodríguez-Escrich (2429539), Adriana Lorente (1457980), Raquel Enrech (1960390), Albert Dordal (10151778), Enrique Portillo-Salido (1859692), Mónica Porras (11524377), Begoña Fernández (2343823), Raquel F. Reinoso (1960381), José Miguel Vela (1638055), Carmen Almansa (1638043)

مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Science Policy, Chemical Sciences not elsewhere classified, showed high selectivity, reduce lipophilicity provided, pyrido ­[ 4, micromolar hts hit, improved analgesic efficacy, gated calcium channels, small alkyl group, piperazinyl bicyclic derivatives, 4 ­( 3, 4 -( 3, >)- one scaffold, v , 1 versus ca, >)- one, central scaffold, butyl group, position 3, 3 -<, selective ligands, safety ratio, r <, probably linked, piperazinyl quinazolin, pharmacological activities, new series

Relation: https://figshare.com/articles/journal_contribution/Piperazinyl_Bicyclic_Derivatives_as_Selective_Ligands_of_the_2_1_Subunit_of_Voltage-Gated_Calcium_Channels/16744425

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00416.s001

المؤلفون: Boeun Lee, Michelle Taylor, Suzy A. Griffin, Tamara McInnis, Nathalie Sumien, Robert H. Mach, Robert R. Luedtke

المصدر: Molecules; Volume 26; Issue 11; Pages: 3182

مصطلحات موضوعية: D2-like dopamine receptors, D3 dopamine receptor subtype, G-protein coupled receptor (GPCR), dopamine receptor subtype selective ligands, bitopic ligands

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules26113182

الاتاحة: https://doi.org/10.3390/molecules26113182

المؤلفون: Mizuki Watanabe, Takaaki Kobayashi, Yoshihiko Ito, Shizuo Yamada, Satoshi Shuto

المصدر: Molecules; Volume 25; Issue 16; Pages: 3562

مصطلحات موضوعية: histamine, H 3 receptor, conformational restriction, selective ligands

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules25163562

الاتاحة: https://doi.org/10.3390/molecules25163562

المؤلفون: Yingpeng Liu, Thanh C. Ho, Mohammed Baradwan, Maria Pascual Lopez-Alberca, Christos Iliopoulos-Tsoutsouvas, Spyros P. Nikas, Alexandros Makriyannis

المصدر: Molecules; Volume 25; Issue 3; Pages: 684

مصطلحات موضوعية: cannabinoids, cannabilactones, CB2 selective ligands, Suzuki cross-coupling

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules25030684

الاتاحة: https://doi.org/10.3390/molecules25030684

المؤلفون: Shakiru O. Alapafuja, Spyros P. Nikas, Thanh C. Ho, Fei Tong, Othman Benchama, Alexandros Makriyannis

المصدر: Molecules; Volume 24; Issue 19; Pages: 3559

مصطلحات موضوعية: cannabinoid receptors, CB2 selective ligands, synthesis, cannabilactones, structure-activity relationship studies

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules24193559

الاتاحة: https://doi.org/10.3390/molecules24193559

المؤلفون: Sefan Asamitsu, Shunsuke Obata, Zutao Yu, Toshikazu Bando, Hiroshi Sugiyama

المصدر: Molecules; Volume 24; Issue 3; Pages: 429

مصطلحات موضوعية: cancer therapy, telomere, oncogenes, G-quadruplex, selective ligands

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules24030429

الاتاحة: https://doi.org/10.3390/molecules24030429

المؤلفون: Asamitsu, Sefan, Obata, Shunsuke, Yu, Zutao, Bando, Toshikazu, Sugiyama, Hiroshi

المساهمون: 朝光, 世煌, 小幡, 俊介, 余, 祖滔, 板東, 俊和, 杉山, 弘, 20345284, 50183843

مصطلحات موضوعية: cancer therapy, telomere, oncogenes, G-quadruplex, selective ligands

وصف الملف: application/pdf

Relation: http://hdl.handle.net/2433/236180; Molecules; 24; 429

الاتاحة: http://hdl.handle.net/2433/236180

المؤلفون: Kabay, Nilgun, Baygu, Yasemin, Kabay, Burhan, Yıldız, Burak, Ömeroğlu, İpek, Durmuş, Mahmut, Karagür, E. Riza

مصطلحات موضوعية: Zn(II)phthalocyanine, Macrocyclization, Click reaction, Singlet oxygen, Molecular docking, in vitro, Zinc(Ii) Phthalocyanine, Selective Ligands, Metal-Free, Electroluminescent, Photosensitizers, Derivatives, Complexes, Docking, Films

Relation: Journal of Molecular Structure; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/11454/89603; https://doi.org/10.1016/j.molstruc.2022.134010; Yildiz, Burak/0000-0001-8283-3230; Ergin, Çağrı/0000-0001-7783-8723; KARAGUR, Ege Riza/0000-0003-2189-8553; 1271

الاتاحة: https://hdl.handle.net/11454/89603
https://doi.org/10.1016/j.molstruc.2022.134010

المؤلفون: Guillerm, Vincent, Xu, Heng, Albalad Alcala, Jorge, Imaz, Inhar, Maspoch Comamala, Daniel

مصطلحات موضوعية: Gas sorption properties, Gas-phase ozonolysis, Mesoporosity, Metal organic framework, Metalorganic frameworks (MOFs), Mixed-ligands, Organic ligands, Selective ligands

وصف الملف: application/pdf

Relation: Ministerio de Economía y Competitividad MAT2015-65354-C2-1-R; Agència de Gestió d'Ajuts Universitaris i de Recerca 2014/SGR-80; European Commission 615954; Ministerio de Economía y Competitividad SEV-2013-0295; Journal of the American Chemical Society; Vol. 140, Issue 44 (November 2018), p. 15022-15030; https://ddd.uab.cat/record/210804; urn:10.1021/jacs.8b09682; urn:oai:ddd.uab.cat:210804; urn:scopus_id:85055971574; urn:articleid:15205126v140n44p15022; urn:wos_id:000449887800063; urn:altmetric_id:49662115; urn:pmid:30351020; urn:icn2uab:4132498

الاتاحة: https://ddd.uab.cat/record/210804

المؤلفون: Montagner, D., Fresch, B., Browne, K., Gandin, V., Erxleben, Andrea

مصطلحات موضوعية: PERIPHERAL BENZODIAZEPINE-RECEPTOR, SELECTIVE LIGANDS, BINDING-AFFINITY, 18 KDA, TSPO, CANCER, SITES, MODEL

وصف الملف: application/pdf

Relation: Chemical Communications; Montagner, D., Fresch, B., Browne, K., Gandin, V., & Erxleben, A. (2017). A Cu(ii) complex targeting the translocator protein: in vitro and in vivo antitumor potential and mechanistic insights. Chemical Communications, 53(1), 134-137. doi:10.1039/C6CC08100B; http://hdl.handle.net/10379/7199

الاتاحة: http://hdl.handle.net/10379/7199
https://doi.org/10.1039/c6cc08100b