المصدر: Phase III Study of ASP1941 - Open-label, Non-comparative Study to Assess the Long-term Safety, Tolerability and Efficacy of ASP1941 in Combination With a Dipeptidyl Peptidase-4 Inhibitor in Japanese Patients With Type 2 Diabetes Mellitus Who Have Inadequate Glycemic Control With a Dipeptidyl Peptidase-4 Inhibitor Alone

Other URLs: https://www.clinicaltrials.astellas.com/transparency/

المؤلفون: Geisinger Clinic, Henry Ford Health System, HealthPartners Institute, Patient-Centered Outcomes Research Institute

المصدر: Comparison of Type 2 Diabetes Pharmacotherapy Regimens Using Targeted Learning

المصدر: A Prospective, Multicenter, Phase -IV Study to Assess the Safety of Fixed Dose Combination of Dapagliflozin and Saxagliptin in Indian Type 2 Diabetes Mellitus (T2D) Patients

Other URLs: https://astrazenecagroup-dt.pharmacm.com/DT/Home

المصدر: Harmonizing RCT-Duplicate Emulations: A Real World Replication Program Analyzing Three Clinical Trials, CANVAS, LEADER, and SAVOR TIMI in Type 2 Diabetes Mellitus

المؤلفون: American Diabetes Association, AstraZeneca, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

المصدر: Preservation of Beta Cell Function in Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

المؤلفون: Bristol-Myers Squibb

المصدر: Effects of Saxagliptin on Adipose Tissue Inflammation in Humans
Kim SH, Liu A, Ariel D, Abbasi F, Lamendola C, Grove K, Tomasso V, Ochoa H, Reaven G. Effect of salsalate on insulin action, secretion, and clearance in nondiabetic, insulin-resistant individuals: a randomized, placebo-controlled study. Diabetes Care. 2014 Jul;37(7):1944-50. doi: 10.2337/dc13-2977.

المؤلفون: Kannan Sridharan, Gowri Sivaramakrishnan

المصدر: Diabetology & Metabolic Syndrome, Vol 17, Iss 1, Pp 1-12 (2025)

مصطلحات موضوعية: Sitagliptin, Saxagliptin, Alogliptin, Lisinopril, Valsartan, Irbesartan, Nutritional diseases. Deficiency diseases, RC620-627

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1758-5996

URL الوصول: https://doaj.org/article/178d34fab95e469c9a1e259e695546b8

المصدر: A 26 Week, Multicenter, Randomized, Placebo-Controlled, Double-Blind, Parallel Group, Phase 3 Trial With a 26 Week Safety Extension Period Evaluating the Safety and Efficacy of Dapagliflozin 5 and 10 mg, and Saxagliptin 2.5 and 5 mg in Pediatric Patients With Type 2 Diabetes Mellitus Who Are Between 10 and Below 18 Years of Age

Other URLs: https://astrazenecagroup-dt.pharmacm.com/DT/Home

المؤلفون: The Sixth Affiliated Hospital of Guangzhou Medical University, Third Affiliated Hospital, Sun Yat-Sen University, Peking University Shenzhen Hospital, Dongguan Kanghua Hospital, First People's Hospital, Shunde China, The First Affiliated Hospital of Guangdong Pharmaceutical University, The Fifth Affiliated Hospital of Zunyi Medical College, Shenzhen Sixth People's Hospital

المصدر: Multicenter Prospective Cohort Study of the Hypoglycemic Efficacy, Weight Control, and Safety in Newly-diagnosed Type 2 Diabetes: Triple Combination Therapy Using Metformin, Saxagliptin Plus Dapagliflozin Versus Premixed Insulin

المساهمون: Haider Ayad Alidrisi, Assistant professor

المصدر: Effect of Short-term Basal Insulin Initiation in Newly Diagnosed Type 2 Diabetes on 1-year Glycemic Control
Weng J, Li Y, Xu W, Shi L, Zhang Q, Zhu D, Hu Y, Zhou Z, Yan X, Tian H, Ran X, Luo Z, Xian J, Yan L, Li F, Zeng L, Chen Y, Yang L, Yan S, Liu J, Li M, Fu Z, Cheng H. Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial. Lancet. 2008 May 24;371(9626):1753-60. doi: 10.1016/S0140-6736(08)60762-X.
Ilkova H, Glaser B, Tunckale A, Bagriacik N, Cerasi E. Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients by transient intensive insulin treatment. Diabetes Care. 1997 Sep;20(9):1353-6. doi: 10.2337/diacare.20.9.1353.
Li Y, Xu W, Liao Z, Yao B, Chen X, Huang Z, Hu G, Weng J. Induction of long-term glycemic control in newly diagnosed type 2 diabetic patients is associated with improvement of beta-cell function. Diabetes Care. 2004 Nov;27(11):2597-602. doi: 10.2337/diacare.27.11.2597.
Ryan EA, Imes S, Wallace C. Short-term intensive insulin therapy in newly diagnosed type 2 diabetes. Diabetes Care. 2004 May;27(5):1028-32. doi: 10.2337/diacare.27.5.1028.

المؤلفون: Shalini Jain, Mukesh Kumar Sharma, Asad Syed, Ali H. Bahkali, Surendra Nimesh, Nidhi Gupta, Sreemoyee Chatterjee

المصدر: Journal of Agriculture and Food Research, Vol 18, Iss , Pp 101462- (2024)

مصطلحات موضوعية: Commiphora wightii, CYP3A11, Guggul extract, Saxagliptin, Synergistic, Type 2 diabetes mellitus, Agriculture (General), S1-972, Nutrition. Foods and food supply, TX341-641

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S266615432400499X; https://doaj.org/toc/2666-1543

URL الوصول: https://doaj.org/article/a2c5f5a490364ebfbe1a3877db4ec36c

المؤلفون: Elsayed A. Elmorsy, Mahmoud E. Youssef, Mohamed R. Abdel-Hamed, Maha M. Amer, Sahar R. Elghandour, Abdullah S. Alkhamiss, Nahla B. Mohamed, Mostafa M. Khodeir, Hossam A. Elsisi, Thamir Saad Alsaeed, Manal M. Kamal, Abousree T. Ellethy, Basem H. Elesawy, Sameh Saber

المصدر: Frontiers in Pharmacology, Vol 15 (2024)

مصطلحات موضوعية: BMS-477118 (saxagliptin), AMPK/SIRT1/FOXO3a, chronic ulcerative colitis, intestinal inflammation/fibrosis, DPP4 inhibitors, novel therapeutic target, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1456058/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/f43b81dbe1f642aabaa4386af9af4885

المساهمون: Shirley Vichy Wang, Assistant Professor

المصدر: Replication of the SAVOR-TIMI Diabetes Trial in Healthcare Claims
Franklin JM, Patorno E, Desai RJ, Glynn RJ, Martin D, Quinto K, Pawar A, Bessette LG, Lee H, Garry EM, Gautam N, Schneeweiss S. Emulating Randomized Clinical Trials With Nonrandomized Real-World Evidence Studies: First Results From the RCT DUPLICATE Initiative. Circulation. 2021 Mar 9;143(10):1002-1013. doi: 10.1161/CIRCULATIONAHA.120.051718. Epub 2020 Dec 17.

المؤلفون: Bristol-Myers Squibb

المساهمون: Leon Fogelfeld MD, Co-Principal Investigator

المصدر: A Pilot Study of Outpatient Discharge Therapy With Saxagliptin + Metformin XR or Sulphonylurea for Recently Diagnosed Type 2 Diabetes Presenting With Severe Hyperglycemia

المساهمون: Sabyasachi Sen, Associate Professor, Dept. of Medicine (Division of Endocrinology)

المصدر: Cardio-Protective of Effect of Saxagliptin and Dapagliflozin Combination on Endothelial Progenitor Cells in Patients With Type 2 Diabetes

المساهمون: P. Barton Duell, M.D., Director, Lipid-Atherosclerosis Laboratory

المصدر: Effects of Dipeptidyl Peptidase-4 Inhibition With Saxagliptin on Fasting and Postprandial Triglyceride Concentrations

المؤلفون: Pankaj M. Kharabe, Prasad P. Jumade, Pravin N. Khatale, Parimal P. Katolkar, Santosh R. Butle, Mahendra D. Kshirsagar, Vishal V. Pendharkar, Amol V. Sawale, Kalyani S. Choudhari

المصدر: Talanta Open, Vol 9, Iss , Pp 100274- (2024)

مصطلحات موضوعية: Dipeptidyl peptidase-4 inhibitors, Evogliptin, Sitagliptin, Saxagliptin, Vildagliptin, Linagliptin, Analytical chemistry, QD71-142

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666831923000942; https://doaj.org/toc/2666-8319

URL الوصول: https://doaj.org/article/37982483b6aa462c90112bac3d492b6e

المساهمون: Prof. Stefano Del Prato, Clinical Resercher

المصدر: A Randomized Study of the Effects of Dapagliflozin+Saxagliptin in Addition to Metformin Versus Single Addition Saxagliptin or Dapagliflozin on Glucose Metabolism in Patients With DM2 Poorly Controlled With Metformin

المساهمون: Ahmed El-Yazbi, Professor

المصدر: Investigating the Protective Effect of Newer Antidiabetic Drugs on Cognitive Decline in Diabetic Patients

المصدر: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial to Evaluate the Safety and Efficacy of Dapagliflozin in Asian Subjects With T2DM and Inadequate Glycemic Control on Metformin and Saxagliptin (DS Navigation)

Other URLs: https://astrazenecagroup-dt.pharmacm.com/DT/Home