المؤلفون: Takaki Maeba, Kazuyuki Hirata, Masayuki Kotoku, Noriyoshi Seki, Katsuya Maeda, Shintaro Hirashima, Hiroshi Yamanaka, Takayuki Sakai, Shingo Obika, Akimi Hori, Yoshinori Hara, Satoru Noji, Yoshihiro Suwa, Masahiro Yokota, Shingo Fujioka, Takayuki Yamaguchi, Yoshiaki Katsuda, Takahiro Hata, Naoki Miyagawa, Kojo Arita, Yukihiro Nomura, Toshio Taniguchi, Kota Asahina, Yusuke Aratsu, Yuichi Naka, Tsuyoshi Adachi, Akihiro Nomura, Shota Akai, Shin-ichi Oshida, Sudhakar Pai, Paul Crowe, Erin Bradley, Ruo Steensma, Haiyan Tao, Morgan Fenn, Robert Babine, Xiaolin Li, Scott Thacher, Takahiro Soeta, Yutaka Ukaji, Makoto Shiozaki

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, serious adverse events, nuclear receptor ligands, likeness ” indices, good pk profiles, good metabolic stability, human clinical trials, human clinical trial, poor physicochemical properties, novel rorγ inhibitor, intensive sar exploration, clinical development, like properties, rorγ program, rorγ inhibitors, “ drug, strong emphasis

Relation: https://figshare.com/articles/journal_contribution/Discovery_and_SAR_of_JTE-151_A_Novel_ROR_Inhibitor_for_Clinical_Development/24937198

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01933.s001
https://figshare.com/articles/journal_contribution/Discovery_and_SAR_of_JTE-151_A_Novel_ROR_Inhibitor_for_Clinical_Development/24937198

المؤلفون: Takaki Maeba, Kazuyuki Hirata, Masayuki Kotoku, Noriyoshi Seki, Katsuya Maeda, Shintaro Hirashima, Hiroshi Yamanaka, Takayuki Sakai, Shingo Obika, Akimi Hori, Yoshinori Hara, Satoru Noji, Yoshihiro Suwa, Masahiro Yokota, Shingo Fujioka, Takayuki Yamaguchi, Yoshiaki Katsuda, Takahiro Hata, Naoki Miyagawa, Kojo Arita, Yukihiro Nomura, Toshio Taniguchi, Kota Asahina, Yusuke Aratsu, Yuichi Naka, Tsuyoshi Adachi, Akihiro Nomura, Shota Akai, Shin-ichi Oshida, Sudhakar Pai, Paul Crowe, Erin Bradley, Ruo Steensma, Haiyan Tao, Morgan Fenn, Robert Babine, Xiaolin Li, Scott Thacher, Takahiro Soeta, Yutaka Ukaji, Makoto Shiozaki

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, serious adverse events, nuclear receptor ligands, likeness ” indices, good pk profiles, good metabolic stability, human clinical trials, human clinical trial, poor physicochemical properties, novel rorγ inhibitor, intensive sar exploration, clinical development, like properties, rorγ program, rorγ inhibitors, “ drug, strong emphasis

Relation: https://figshare.com/articles/dataset/Discovery_and_SAR_of_JTE-151_A_Novel_ROR_Inhibitor_for_Clinical_Development/24937201

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01933.s002
https://figshare.com/articles/dataset/Discovery_and_SAR_of_JTE-151_A_Novel_ROR_Inhibitor_for_Clinical_Development/24937201