المؤلفون: Burgos-Molina, Antonio Manuel, Peinado-Ruiz, Isabel C., González Vidal, Alejandro, Ruiz-Gómez, Miguel José

مصطلحات موضوعية: Oncological resistance to chemotherapy and radiotherapy, Increased resistance to drugs, Longer life cycle

Relation: 18th ASEICA INTERNATIONAL CONGRESS; Santiago de Compostela, España.; 16 al 18 de Noviembre 2022; https://hdl.handle.net/10630/25656

الاتاحة: https://hdl.handle.net/10630/25656

المؤلفون: Kladnik, Jerneja, Coverdale, James P. C., Kljun, Jakob, Burmeister, Hilke, Lippman, Petra, Ellis, Francesca G., Jones, Alan M., Ott, Ingo, Romero-Canelón, Isolda, Turel, Iztok

المصدر: Cancers, vol. 13, no. 10, 2493, 2021. ; ISSN: 2072-6694

مصطلحات موضوعية: ruthenium, pyrithione, resistance to chemotherapy, cancer, ovarian, thioredoxin, rutenij, organorutenijevi kompleksi, piritioni, rak jajčnikov, info:eu-repo/classification/udc/546.96:547.8:618.11-006

وصف الملف: application/pdf; text/url

Relation: https://repozitorij.uni-lj.si/IzpisGradiva.php?id=135447; https://repozitorij.uni-lj.si/Dokument.php?id=154534&dn=; https://repozitorij.uni-lj.si/Dokument.php?id=154533&dn=; https://plus.cobiss.net/cobiss/si/sl/bib/64129539; http://hdl.handle.net/20.500.12556/RUL-135447

الاتاحة: https://repozitorij.uni-lj.si/IzpisGradiva.php?id=135447
https://repozitorij.uni-lj.si/Dokument.php?id=154534&dn=
https://repozitorij.uni-lj.si/Dokument.php?id=154533&dn=
https://plus.cobiss.net/cobiss/si/sl/bib/64129539
https://hdl.handle.net/20.500.12556/RUL-135447

المؤلفون: Kovachka, Sandra, Malloci, Giuliano, Simsir, Méliné, Ruggerone, Paolo, Azoulay, Stéphane, Mus-Veteau, Isabelle

المساهمون: Institut de Chimie de Nice (ICN), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UniCA), Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UniCA), Università degli Studi di Cagliari = University of Cagliari (UniCa), G.M. and P. R. acknowledge support by National Institute of Allergy and Infectious Diseases/NIH grant no. R01AI136799., Région PACA, ANR-15-IDEX-0001,UCA JEDI,Idex UCA JEDI(2015), European Project: 847581,H2020,H2020-MSCA-COFUND-2018,BoostUrCAreer(2019)

المصدر: ISSN: 0223-5234.

مصطلحات موضوعية: Resistance to chemotherapy, Multidrug efflux pump, Ptch1, Hedgehog signaling, drug efflux pump inhibitors, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, [SDV.CAN]Life Sciences [q-bio]/Cancer

Relation: info:eu-repo/semantics/altIdentifier/pmid/35421658; info:eu-repo/grantAgreement//847581/EU/Boosting PhD employability @UCA/BoostUrCAreer; hal-03845877; https://hal.science/hal-03845877; https://hal.science/hal-03845877/document; https://hal.science/hal-03845877/file/Review-EJMC_revised2.pdf; PUBMED: 35421658

الاتاحة: https://hal.science/hal-03845877
https://hal.science/hal-03845877/document
https://hal.science/hal-03845877/file/Review-EJMC_revised2.pdf
https://doi.org/10.1016/j.ejmech.2022.114306

المؤلفون: Kaname Uno, Shohei Iyoshi, Masato Yoshihara, Kazuhisa Kitami, Kazumasa Mogi, Hiroki Fujimoto, Mai Sugiyama, Yoshihiro Koya, Yoshihiko Yamakita, Akihiro Nawa, Tomohiro Kanayama, Hiroyuki Tomita, Atsushi Enomoto, Hiroaki Kajiyama

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 8; Pages: 4383

مصطلحات موضوعية: ovarian cancer, ascites, spheroid, hetero-cellular spheroid, metastasis, anoikis, resistance to chemotherapy, mesothelial cell, macrophage, genetic evolution

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms23084383

الاتاحة: https://doi.org/10.3390/ijms23084383

المؤلفون: Villa C., Chaplain M. A. J., Lorenzi T.

المساهمون: Villa, C., Chaplain, M. A. J., Lorenzi, T.

مصطلحات موضوعية: Evolutionary dynamic, Intra-tumour heterogeneity, Mathematical oncology, Non-local partial differential equation, Resistance to chemotherapy, Vascularised tumours

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000576130300001; volume:49; firstpage:143; lastpage:167; numberofpages:25; journal:VIETNAM JOURNAL OF MATHEMATICS; http://hdl.handle.net/11583/2870764

الاتاحة: http://hdl.handle.net/11583/2870764
https://doi.org/10.1007/s10013-020-00445-9
https://link.springer.com/article/10.1007/s10013-020-00445-9

المؤلفون: Andrea Magali González-Mora, Patricia Garcia-Lopez

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 22; Pages: 12404

مصطلحات موضوعية: glioblastoma, endocrine therapy, estrogen receptors, drugs, resistance to chemotherapy

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Oncology; https://dx.doi.org/10.3390/ijms222212404

الاتاحة: https://doi.org/10.3390/ijms222212404

المؤلفون: Jerneja Kladnik, James P. C. Coverdale, Jakob Kljun, Hilke Burmeister, Petra Lippman, Francesca G. Ellis, Alan M. Jones, Ingo Ott, Isolda Romero-Canelón, Iztok Turel

المصدر: Cancers; Volume 13; Issue 10; Pages: 2493

مصطلحات موضوعية: ruthenium, pyrithione, resistance to chemotherapy, cancer, ovarian, thioredoxin

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cancers13102493

الاتاحة: https://doi.org/10.3390/cancers13102493

المؤلفون: Takanobu Jotatsu, Shigehiro Yagishita, Ken Tajima, Fumiyuki Takahashi, Kaoru Mogushi, Moulid Hidayat, Aditya Wirawan, Ryo Ko, Ryota Kanemaru, Naoko Shimada, Keiko Mitani, Tsuyoshi Saito, Kazuya Takamochi, Kenji Suzuki, Shinji Kohsaka, Shinya Kojima, Hiroshi Mukae, Kazuhiro Yatera, Kazuhisa Takahashi

المصدر: Biochemistry and Biophysics Reports, Vol 9, Iss C, Pp 86-94 (2017)

مصطلحات موضوعية: LSD1, LSD1+8a, KDM, SCLC, Neuroendocrine marker, Resistance to chemotherapy, Biology (General), QH301-705.5, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405580816303235; https://doaj.org/toc/2405-5808

URL الوصول: https://doaj.org/article/3699b390fa0f405b893602cb869cc4e3

المؤلفون: Anil Mishra

المصدر: Int. J. Basic Clin. Immonol, 3(1-4), 1-8, (2020-12-22)

مصطلحات موضوعية: Objectives: Pancreatic malignancy is a major public health problem worldwide and recent reports indicated that pancreatic cancer will be second most common cause of cancer-related deaths by the end of 2021. The cause of increasing death rate is due to the nonexistence of detection tools to early diagnose, poor prognosis, resistance to chemotherapy and also lack in understanding the mechanism of PDAC pathogenesis. Circulating tumor cells (CTCs) play a major role in metastatic step of intravasation and presence of these cells are strong prognostic marker for the progression of pancreatic malignancy in chronic pancreatitis (CP). Goal: Identifying the novel CTCs in the chronic inflammation mediated experimental model for the progression of malignancy in CP. Methods: We have performed flow cytometer and immunofluorescence analyses were performed in the lymphoid and lung samples to detect CTCs in the chronic inflammation (Cerulin and Azoxymethane) induced CP mouse model. Results: We report that induced SOX9 positive cells were observed in the blood, lymph node and spleen samples of cerulein with azoximethane (AOM) treated mice compared to cerulein alone. Further, we provide evidence that early metastasis through the migration and homing of mega merged SOX9+ and PDX+ ductal stem cells (CTCs) in the lungs of cerulein with AOM treated mice. These identified CTCs in experimentally induced malignant pancreatitis may serve as a novel finding to identify a non-invasive biomarker that needs to be examined in the blood of human pancreatic cancer. Conclusions: Taken together, the presented data of identified mega merged SOX9+ and PDX+ ductal stem cells (CTCs) may serve a non-invasive biomarker for the early detection of pancreatic malignancy and metastasis

Relation: https://doi.org/10.1076/iJbCI.ISP; oai:zenodo.org:4386111

الاتاحة: https://doi.org/10.1076/iJbCI.ISP

المؤلفون: Wróbel Tomasz, Stefanko Ewa, Dzietczenia Justyna, Jaźwiec Bożena, Mazur Grzegorz, Haus Olga, Dybko Jarosław, Kuliczkowski Kazimierz

المصدر: Open Medicine, Vol 9, Iss 2, Pp 204-209 (2014)

مصطلحات موضوعية: Acute myeloid leukemia, GRP78, Resistance to chemotherapy, Medicine

وصف الملف: electronic resource

Relation: http://www.degruyter.com/view/j/med.2014.9.issue-2/s11536-013-0200-7/s11536-013-0200-7.xml?format=INT; https://doaj.org/toc/2391-5463

URL الوصول: https://doaj.org/article/df44299a13a44f849cd07b2cc9330b5a

المؤلفون: Sáez-Calvo, Gonzalo, Balaguer, Francisco de Asís, Barasoain, Isabel, Rodríguez-Salarichs, Javier, Muñoz-Hernández, Hugo, Berbís, Manuel Álvaro, Peñalva, Miguel Ángel, Matesanz, Ruth, Canales, Ángeles, Jiménez-Barbero, Jesús, Andreu, José Manuel, Díaz, José Fernando

المساهمون: Ministerio de Economía y Competitividad (España), Swiss National Science Foundation

مصطلحات موضوعية: Tubulin, Microtubules, Microtubule‐targeting agents, Antitumourals, Resistance to chemotherapy

Relation: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BFU2016‐75319‐R; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BFU2014‐51823‐R; Postprint; https://doi.org/10.1016/j.chembiol.2017.05.016; Sí; Cell Chemical Biology 24 (6) 737–750.e6 (2017); http://hdl.handle.net/10261/152590; http://dx.doi.org/10.13039/501100003329

الاتاحة: http://hdl.handle.net/10261/152590
https://doi.org/10.1016/j.chembiol.2017.05.016
https://doi.org/10.13039/501100003329

المؤلفون: Patricia Garcia-Lopez, Andrea Magali González-Mora

المصدر: International Journal of Molecular Sciences, Vol 22, Iss 12404, p 12404 (2021)
International Journal of Molecular Sciences

مصطلحات موضوعية: Gene isoform, Selective Estrogen Receptor Modulators, Hormone Replacement Therapy, QH301-705.5, Cell, Estrogen receptor, Antineoplastic Agents, Review, Catalysis, drugs, Inorganic Chemistry, Gonadotropin-Releasing Hormone, resistance to chemotherapy, Medicine, Estrogen Receptor beta, Humans, Protein Isoforms, Molecular Targeted Therapy, Physical and Theoretical Chemistry, Biology (General), Receptor, Molecular Biology, QD1-999, Spectroscopy, business.industry, Aromatase Inhibitors, Brain Neoplasms, endocrine therapy, Organic Chemistry, Estrogen Receptor alpha, glioblastoma, estrogen receptors, General Medicine, medicine.disease, Primary tumor, Computer Science Applications, Chemistry, medicine.anatomical_structure, Treatment Outcome, Mechanism of action, Nuclear receptor, Cancer research, medicine.symptom, business, Hormone, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebc1cfa7b78cd38cac5acfc1227a5da
https://www.mdpi.com/1422-0067/22/22/12404

المؤلفون: Luciana Maria Silva, Agnaldo Lopes da Silva Filho, Letícia da Conceição Braga, Nikole Gontijo Gonçales, Warne Pedro de Andrade

المساهمون: Vera Cruz Hosp, Universidade Estadual Paulista (Unesp), Ezequiel Dias Fdn, Minas Gerais Fed Univ

المصدر: Oncology Letters
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, endocrine system diseases, TRAF1, medicine.disease_cause, 03 medical and health sciences, 0302 clinical medicine, resistance to chemotherapy, Heat shock protein, Medicine, HSPA1L, Oncogene, Ovarian serous cystadenoma, business.industry, Cancer, Articles, medicine.disease, female genital diseases and pregnancy complications, 030104 developmental biology, ovarian cancer, Oncology, 030220 oncology & carcinogenesis, heat shock proteins, Cancer research, gene expression, prognosis, business, Ovarian cancer, Carcinogenesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cbae13c5da62fc7758acc443f7809ca
http://europepmc.org/articles/PMC6923843

المؤلفون: Chiara Villa, Mark A. J. Chaplain, Tommaso Lorenzi

المساهمون: University of St Andrews. School of Mathematics and Statistics, University of St Andrews. Applied Mathematics

مصطلحات موضوعية: 0303 health sciences, Asymptotic analysis, Resistance to chemotherapy, Genetic heterogeneity, RC0254 Neoplasms. Tumors. Oncology (including Cancer), General Mathematics, T-NDAS, Vascularised tumours, Mathematical oncology, Intra-tumour heterogeneity, RC0254, 03 medical and health sciences, 0302 clinical medicine, SDG 3 - Good Health and Well-being, 030220 oncology & carcinogenesis, Evolutionary dynamics, Non-local partial differential equations, QA Mathematics, Biological system, QA, 030304 developmental biology, Mathematics

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30b3a10132d7963919e267444a747383
https://hdl.handle.net/10023/20767

المؤلفون: Velasco, Guillermo, Lorente, Mar, Torres, Sofía, Salazar, María, Carracedo, Arkaitz, Hernández-Tiedra, Sonia, Rodríguez-Fornés, Fátima, García-Taboada, Elena, Meléndez, Bárbara, Mollejo, Manuela, Campos, Yolanda, Lakatosh, Sergey, Barcia, Juan, Guzmán, Manuel

المساهمون: Biochemistry and Molecular Biology I

المصدر: ISSN: 1350-9047.

مصطلحات موضوعية: cannabinoids, glioma, midkine, autophagy, resistance to chemotherapy

Relation: hal-00608712; https://hal.archives-ouvertes.fr/hal-00608712; https://hal.archives-ouvertes.fr/hal-00608712/document; https://hal.archives-ouvertes.fr/hal-00608712/file/PEER_stage2_10.1038%252Fcdd.2010.170.pdf

الاتاحة: https://hal.archives-ouvertes.fr/hal-00608712
https://hal.archives-ouvertes.fr/hal-00608712/document
https://hal.archives-ouvertes.fr/hal-00608712/file/PEER_stage2_10.1038%252Fcdd.2010.170.pdf
https://doi.org/10.1038/cdd.2010.170

المؤلفون: De Andrade, Warne Pedro, Braga, Leticia Da Conceicao, Goncales, Nikole Gontijo, Silva, Luciana Maria, Da Silva Filho, Agnaldo Lopes

المساهمون: Universidade Estadual Paulista (UNESP)

مصطلحات موضوعية: ovarian cancer, prognosis, resistance to chemotherapy, heat shock proteins, gene expression

وصف الملف: 359-367

Relation: Oncology Letters; http://dx.doi.org/10.3892/ol.2019.11095; Oncology Letters. Athens: Spandidos Publ Ltd, v. 19, n. 1, p. 359-367, 2020.; http://hdl.handle.net/11449/196508; WOS:000508369500040

الاتاحة: http://hdl.handle.net/11449/196508
https://doi.org/10.3892/ol.2019.11095

المؤلفون: Ni Liu, Dan Pi, Chun-Mei Liu

المصدر: Journal of Hainan Medical University, Vol 24, Iss 01, Pp 5-8 (2018)

مصطلحات موضوعية: GRP78, endocrine system diseases, 409000. Fund Project: Science and Technology Project of Qianjiang District No: 2016056. 1. Introduction Ovarian cancer is one of the most common malignant tumors in the female reproductive system. Surgical resection and chemotherapy are the main treatments. Because ovarian cancer cells are more sensitive to chemotherapy drugs, Proliferation, DMEM, RIPA lysate was purchased in Shanghai Beyotime Company, lcsh:Medicine, Invasion, Chongqing, Ovarian cancer, especially platinum drugs, and enzyme-linked immunosorbent assay kits were purchased from Shanghai Westang Biotechnology Company. Objective: To study the effect of metformin combined with cisplatin on the expression of genes related to ovarian cancer cell growth and invasion in vitro. Methods: SKOV3 ovarian cancer cell lines were cultured and randomly divided into the control group treated with serumfree DMEM, the platinum-based intravenous chemotherapy is widely used in the treatment of advanced ovarian cancer[1, CyclinD1, the MET group treated with serum-free DMEM containing 10 mmol/L metformin and the DDP+MET group treated with serum-free DMEM containing 10 μmol/L cisplatin and 10 mmol/L metformin. Results: 24 h after treatment, some patients with ovarian cancer can develop drug resistance during chemotherapy, lcsh:R, TBX2, it has been confirmed in recent years that it has anti-tumor effect and chemotherapy drug sensitization effect, the growth and invasion of cancer cells involve the changes in the expression of multiple proliferationrelated genes and invasion-related genes. In the following studies, Metformin, the DDP group treated with serum-free DMEM containing 10 μmol/L cisplatin, Department of Obstetrics and Gynecology, which will affect the efficacy of chemotherapy[3]. Metformin is a kind of insulin sensitizer for diabetes treatment, Ki-67, Chongqing Qianjiang National Hospital, and its combination with a variety of chemotherapy drugs can enhance the killing effect of chemotherapy drugs on tumor cells[4]. In the progression of the course of ovarian cancer, Cisplatin, we specifically analyzed the effects of metformin combined with cisplatin on the expression of genes associated with ovarian cancer cell growth and invasion in vitro. 2. Experimental materials and methods 2.1 Experimental materials Ovarian cancer SKOV3 cell lines were bought in the cell bank of Chinese Academy of Sciences, fetal bovine serum and 0.125% trypsin for cell culture were purchased in Hyclone Company, cisplatin and metformin were bought in the Sigma Company

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doajarticles::16fad23fa1edb18a83ef8d91d15c2700
http://www.hnykdxxb.com/PDF/201801/02.pdf

المؤلفون: Jian Liu, Jiabei He, Hong-Jen Lee, Chia Hsin Chan, Hui Kuan Lin, Diane Ruan, Chien-Feng Li

المصدر: Oncogene

مصطلحات موضوعية: Male, 0301 basic medicine, cancer stem cell, Cancer Research, Epithelial-Mesenchymal Transition, medicine.medical_treatment, Blotting, Western, Population, Fluorescent Antibody Technique, Mice, Transgenic, Biology, urologic and male genital diseases, Polymerase Chain Reaction, Article, Metastasis, Targeted therapy, Mice, 03 medical and health sciences, Prostate cancer, Cancer stem cell, Genetics, medicine, SKP2, Animals, Immunoprecipitation, Humans, Castration, Twist, education, S-Phase Kinase-Associated Proteins, Molecular Biology, castration resistance and chemotherapy, education.field_of_study, Stem Cells, Twist-Related Protein 1, Prostatic Neoplasms, medicine.disease, 3. Good health, Disease Models, Animal, Prostatic Neoplasms, Castration-Resistant, 030104 developmental biology, Tumor progression, Neoplastic Stem Cells, Disease Progression, Cancer research, Skp2, Stem cell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f464ae3c04958a46a02bc8b2a61047
https://doi.org/10.1038/onc.2017.64

المؤلفون: Bernardo, Sara

Thesis Advisors: Montpellier, Maraver, Antonio

مصطلحات موضوعية: Cancer du poumon, Voie de signalisation Notch et DDR, Traitement du cancer bronchique, Résistance chimio-Induite, Lung cancer, Notch and DNA damage pathways, Lung cancer therapy, Resistance to chemotherapy

الاتاحة: http://www.theses.fr/2019MONTT029

المؤلفون: Fernandez, Solène

المساهمون: Bordeaux, Vigon, Isabelle

مصطلحات موضوعية: Oncologie, Leucémie, CRISPR/cas9, Signalisation, Resistance à la chimiothérapie, Cellules souches, Oncology, Leukemia, Signalling pathway, Resistance to chemotherapy, Stem cells

Relation: http://www.theses.fr/2020BORD0281/document

الاتاحة: http://www.theses.fr/2020BORD0281/document