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    Figure 8. Loss of Fltp or Dlg3 leads to BB mispositioning in IE hair cells. ; (A–D) LSM of Fltp+/+; Dlg3-Venus (WT) IE HCs at E18.5 reveals BBs in the middle of the lateral Dlg3-Venus crescent. (B′–D′) IMARIS surface rendering pictures of WT HCs. (E–H) LSM of FltpZV/ZV; Dlg3-Venus (HOM) IE HCs at E18.5. BBs are located at the edge of the lateral Dlg3-Venus crescent. The crescent itself often shows defective localization. The red asterisk marks some affected cells. (F′–H′) IMARIS surface rendering pictures of HOM HCs. For quantification see Figure 8—figure supplement 1A. (I) For BB mispositioning analyses the angle between the middle of the Dlg3-Venus crescent and the BB location was measured. (J) BB position in affected HCs of HOM animals significantly differs from the position in the WT. In total we analyzed n = 2 (73 cells) for WT and n = 2 (119) for HOM. (K) LSM of Dlg3−/− (Dlg3tm1Grnt) IE HCs reveals mislocalized BBs and rotated hair cells. For quantification Figure 8—figure supplement 1B,C. (L) Analysis of BB mispositioning was performed as described in (I). BB position in affected HCs of Dlg3−/− (HOM) animals significantly differs from the Dlg3+/+ (WT) position. In total we analyzed n = 7 (470 cells) for WT and n = 13 (804) for HOM. Statistical analysis uses an one-way ANOVA (J) or a Kruskal–Wallis test (L) (****p < 0.0001). Error bars show the 95% confidence interval of the mean. The actin network and stereocilia are marked by Phalloidin (Phall), BBs by pericentrin (Peric), cilia by acetylated-Tubulin (aT), and Dlg3-Venus fusion protein by GFP. Abbreviation: inner hair cell (IHC), outer hair cell (OHC 1-3). Scale bars; 10 µm (A and E), 1 µm (B–D′, F–H′, K).
  2. 2
    Dissertation/ Thesis

    المؤلفون: Zamazal, Zdeněk

    المساهمون: Zemčík, Pavel, Přibyl, Jaroslav

    وصف الملف: application/pdf; text/html

    Relation: ZAMAZAL, Z. Optimalizované sledování paprsku [online]. Brno: Vysoké učení technické v Brně. Fakulta informačních technologií. 2009.; 25530; http://hdl.handle.net/11012/54489

  3. 3
    Electronic Resource
  4. 4
    Dissertation/ Thesis

    المؤلفون: Zamazal, Zdeněk

    المساهمون: Zemčík, Pavel, Přibyl, Jaroslav

    المصدر: ZAMAZAL, Z. Optimalizované sledování paprsku [online]. Brno: Vysoké učení technické v Brně. Fakulta informačních technologií. 2009.

    وصف الملف: text/html

  5. 5
    Academic Journal
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    Academic Journal

    المؤلفون: Fair, John D.

    المصدر: Sport History Review; Nov2022, Vol. 53 Issue 2, p249-271, 23p

    مصطلحات موضوعية: SUSPICION, ANTISEMITISM, HOMOPHOBIA, ALCOHOLISM

    People: BOSCO, Harry

  7. 7
    Academic Journal

    المصدر: Cybernetics & Information Technologies; Nov2015, Vol. 15 Issue 4, p124-137, 14p

  8. 8
    Academic Journal
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    Academic Journal

    المصدر: ACM Transactions on Software Engineering & Methodology; Sep2023, Vol. 32 Issue 5, p1-62, 62p

  10. 10
    Academic Journal
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    Academic Journal

    المصدر: Journal of Visualization; Apr2023, Vol. 26 Issue 2, p423-440, 18p

  12. 12
    Academic Journal
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    Academic Journal

    المصدر: Visual Studies; Dec2022, Vol. 37 Issue 5, p415-419, 5p

    مصطلحات موضوعية: FASHION, BUSINESS attire, COMEDIANS, COMEDY, NARRATIVES, ORAL history

  14. 14
    Conference

    المؤلفون: He, Huaxue

    المصدر: Proceedings of SPIE; 7/25/2024, Vol. 12969, p129690B-129690B-6, 1p

  15. 15
    Academic Journal

    المصدر: Physical Chemistry Chemical Physics (PCCP); 8/21/2021, Vol. 23 Issue 31, p16948-16957, 10p

  16. 16
    Academic Journal
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    Academic Journal
  18. 18
    Academic Journal

    المؤلفون: Chan, Ivonbony, Au, Joe, Ho, Chupo, Lam, Jin

    المصدر: International Journal of Fashion Design, Technology & Education; Mar2021, Vol. 14 Issue 1, p78-90, 13p

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    Academic Journal
  20. 20
    Academic Journal

    المؤلفون: Ting Zang, Dongbin Zhu, Guowang Mu

    المصدر: CMES-Computer Modeling in Engineering & Sciences; 2020, Vol. 125 Issue 2, p597-610, 14p