المؤلفون: Bixing Ye, Yanjuan Wang, Lin Lin, Liuqin Jiang, Meifeng Wang

المصدر: Frontiers in Medicine, Vol 8 (2021)

مصطلحات موضوعية: gastroesophageal reflux disease, sex, reflux episode, mean nocturnal baseline impedance, post-reflux swallow-induced peristaltic wave index, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2021.629302/full; https://doaj.org/toc/2296-858X

URL الوصول: https://doaj.org/article/9fc6cd6826a64207944d8ee716c7d291

المؤلفون: Giovanni Dapri, Sven Saussez, Francois Mouawad, Francois Bobin, Marie-Paule Thill, Pierre Eisendrath, Charelle Salem, Vinciane Muls, Jerome R. Lechien, Alexandra Rodriguez, Didier Dequanter, Mihaela Horoi

المساهمون: Hôpital Foch [Suresnes], Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), ELSAN-Polyclinique de Poitiers, Université Lille 2 - Faculté de Médecine, BE076201837630 International Business Machines Corporation, IBM Medtronic Minneapolis Heart Institute, MHI, Patients with LPR symptoms and findings were recruited from three European hospitals (University Hospital Centers Saint-Pierre and Cesar De Pape Hospital, Brussels, Belgium, and Polyclinic of Poitiers?Elsan, Poitiers, France) from January 2018 to October 2019. The diagnosis was confirmed through positive HEMII-pH. Gastrointestinal (GI) endoscopy was proposed to elderly patients and those with GERD symptoms. The exclusion criteria were similar to those described in a previous publication.10 The local ethics committee approved the study protocol (no. BE076201837630). Patients were invited to participate and the informed consent was obtained. The local ethics committee approved the study protocol (no. BE076201837630). Patients were invited to participate and the informed consent was obtained. Patients with LPR symptoms and findings were recruited from three European hospitals (University Hospital Centers Saint-Pierre and Cesar De Pape Hospital, Brussels, Belgium, and Polyclinic of Poitiers?Elsan, Poitiers, France) from January 2018 to October 2019. The diagnosis was confirmed through positive HEMII-pH. Gastrointestinal (GI) endoscopy was proposed to elderly patients and those with GERD symptoms. The exclusion criteria were similar to those described in a previous publication.10 The characteristics of a HEMII-pH monitoring device, placement, and analyses have been described in previous publications.10 Briefly, the HEMII-pH probe was placed in the morning before breakfast (8:00 am). HEMII-pH probe was composed of eight impedance segments and two pH electrodes (Versaflex Z, Digitrapper pH-Z testing system, Medtronic, Minneapolis, MN). Six impedance segments were placed along the esophagus zones (Z1 to Z6), and they were centered at 19, 17, 11, 9, 7, and 5 cm above the LES. Two additional impedance segments were placed 1 and 2 cm above the cricopharyngeal sphincter in the hypopharynx. The pH electrodes were placed 2 cm above the LES and 1 to 2 cm below the cricopharyngeal sphincter, respectively. The proximal (hypopharyngeal) reflux event was defined as an episode that reached two impedance sensors in the hypopharynx. The LPR diagnosis was based on the occurrence of ?1 acid or nonacid HRE.11 The acid reflux episode consisted of an episode with pH ? 4.0. The nonacid reflux episode consisted of an episode with pH > 4.0. Respecting the type of reflux episodes (acid and nonacid), three physicians (f.b., v.m., and c.s.) analyzed the HEMII-pH form to isolate the reflux episodes regarding the following periods of the 24-hour testing: 60 minutes after breakfast, the time between the 60 minutes after breakfast and lunch, the 60 minutes after lunch, the time between the 60 minutes after lunch and dinner, the 60 minutes after dinner, the time between the 60 minutes after dinner and bedtime and nighttime. Patients were off of PPIs during the HEMII-pH testing. Simultaneously to HEMII-pH monitoring, patients were invited to collect saliva samples (1 to 5 mL, throat sputum) 1 to 2 hours after the meals (lunch and dinner) and in the morning (fasting) to study the relationship between HEMII-pH episodes and the saliva pepsin concentrations. The saliva samples were collected into a 30-mL universal sample collection tube containing a pre-established concentration of citric acid to preserve the action of any pepsin present (Peptest kit, RDBiomed, Cottingham, United Kingdom). The pepsin sample collections were stored in the refrigerator. The measurement of pepsin concentration in the saliva samples was performed through the Peptest device (RDBiomed). A trained lab technician received the samples the day following the collection. The steps for pepsin measurement were performed in a standardized procedure, which has been previously described.12 The saliva pepsin concentration was measured using the Cube Reader (opTricon, Berlin, Germany), which detects pepsin down to 16 ng/mL. If the results did not reach that level, the test was considered negative. Symptoms and findings were assessed with Reflux Symptom Score (RSS)13 and Reflux Sign Assessment (RSA),14 respectively. RSS is a self-administered, validated 22-item reported-outcome questionnaire assessing frequency and severity of ear, nose, throat, digestive, and respiratory complaints (Fig. 1). RSA is a validated 61-point LPR physical finding score documenting laryngeal and extralaryngeal findings (Fig. 2). Statistical analyses were performed using the Statistical Package for the Social Sciences for Windows (SPSS version 22,0, IBM, Armonk, NY). The relationships between the HEMII-pH data, the pepsin saliva concentration, and the clinical features were investigated through multiple linear regression. The potential comparison between patient groups with different HEMII-pH profiles was made through Mann-Whitney U test. A level of significance of P <.05 was used. Patients were recruited from three European hospitals from January 2018 to October 2019. Patients benefited from HEMII-pH monitoring and saliva collections to measure saliva pepsin concentration in the same time. Saliva pepsin concentration was measured in the morning (fasting), after lunch, and after dinner. The LPR profile of patients was studied through a breakdown of the HEMII-pH findings over the 24 hours of testing. The relationship between the concentrations of saliva pepsin and 24-hour HREs was studied through linear multiple regression., Faculté de Médecine Henri Warembourg - Université de Lille

المصدر: Laryngoscope
Laryngoscope, Wiley, 2021, 131 (2), pp.268-276. ⟨10.1002/lary.28736⟩

مصطلحات موضوعية: Male, Saliva, Laryngitis, Gastroenterology, Laryngopharyngeal reflux, 0302 clinical medicine, Pepsin, Electric Impedance, Medicine, Prospective Studies, [SHS.LANGUE]Humanities and Social Sciences/Linguistics, 030223 otorhinolaryngology, Morning, Aged, 80 and over, profile, treatment, biology, Middle Aged, pharyngeal, Postprandial Period, 3. Good health, Female, 030211 gastroenterology & hepatology, Adult, medicine.medical_specialty, Esophageal pH Monitoring, Laryngopharyngeal, Photoperiod, reflux episode, Ph monitoring, Young Adult, 03 medical and health sciences, Esophagus, Internal medicine, Laryngopharyngeal Reflux, Humans, laryngitis, Aged, pepsin, business.industry, pH monitoring, Reflux, medicine.disease, Pepsin A, Hypopharynx, Otorhinolaryngology, impedance, biology.protein, Esophageal impedance, reflux, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32d9753fe28024282423b1a7f21e22a0
https://doi.org/10.1002/lary.28736

المؤلفون: Lechien, Jerome, Carroll, Thomas, Bobin, Francois, Muls, Vinciane, Rodriguez, Alexandra, Horoi, Mihaela, Dequanter, Didier, Crevier-Buchman, Lise, Hans, Stéphane, Saussez, Sven

المساهمون: Université de Mons (UMons), Centre Hospitalier Universitaire Brugmann Bruxelles (CHU), CHU Saint-Pierre, Faculté de Médecine Bruxelles (ULB), Université libre de Bruxelles (ULB), Harvard Medical School Boston (HMS), Brigham and Women's Hospital Boston, LPP - Laboratoire de Phonétique et Phonologie - UMR 7018 (LPP), Université Sorbonne Nouvelle - Paris 3-Centre National de la Recherche Scientifique (CNRS), Hôpital Foch Suresnes, Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)

المصدر: ISSN: 0886-4470 ; Archives of Otolaryngology Head and Neck Surgery ; https://shs.hal.science/halshs-03379981 ; Archives of Otolaryngology Head and Neck Surgery, 2021, pp.019459982110202. ⟨10.1177/01945998211020284⟩.

مصطلحات موضوعية: Laryngopharyngeal, Reflux, Laryngitis, PH monitoring, Impedance, Reflux episode, Age, Gender, Sex, Treatment, [SHS.LANGUE]Humanities and Social Sciences/Linguistics

Relation: halshs-03379981; https://shs.hal.science/halshs-03379981

الاتاحة: https://shs.hal.science/halshs-03379981
https://doi.org/10.1177/01945998211020284

المؤلفون: Lechien, Jér̂ome René, Bobin, François, Dequanter, Didier, Rodriguez, Alexandra, Le Bon, Serge Daniel, Horoi, Mihaela, Thill, Marie Paule, Salem, Charelle, Muls, Vinciane, Saussez, Sven

المساهمون: Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Hôpital Foch Suresnes, ELSAN-Polyclinique de Poitiers, CHU Saint-Pierre, Université libre de Bruxelles (ULB), Vesale Grant & IRIS-Recherche Grant (Foundation Roi Baudouin). The author(s) received no financial support for the research, authorship, and/or publication of this article.

المصدر: ISSN: 0003-4894.

مصطلحات موضوعية: impedance, laryngitis, laryngopharyngeal, pepsin, pH monitoring, pharyngeal, profile, reflux, reflux episode, treatment, [SHS.LANGUE]Humanities and Social Sciences/Linguistics

Relation: info:eu-repo/semantics/altIdentifier/pmid/33467863; hal-03401798; https://hal.science/hal-03401798; PUBMED: 33467863

الاتاحة: https://hal.science/hal-03401798
https://doi.org/10.1177/0003489420986347

المؤلفون: Gyawali, C Prakash, Tutuian, Radu, Zerbib, Frank, Rogers, Benjamin D, Frazzoni, Marzio, Roman, Sabine, Savarino, Edoardo, de Bortoli, Nicola, Vela, Marcelo F, Sifrim, Daniel

المساهمون: Gyawali, C Prakash, Tutuian, Radu, Zerbib, Frank, Rogers, Benjamin D, Frazzoni, Marzio, Roman, Sabine, Savarino, Edoardo, de Bortoli, Nicola, Vela, Marcelo F, Sifrim, Daniel

مصطلحات موضوعية: Acid Exposure Time, Gastroesophageal Reflux Disease, Proton Pump Inhibitor, Reflux Episode, pH Impedance Monitoring

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/34270955; info:eu-repo/semantics/altIdentifier/wos/WOS:000750577700017; volume:161; issue:5; firstpage:1412; lastpage:1422; numberofpages:11; journal:GASTROENTEROLOGY; https://hdl.handle.net/11568/1189547; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85115090465

الاتاحة: https://hdl.handle.net/11568/1189547
https://doi.org/10.1053/j.gastro.2021.07.004

المؤلفون: Bobin, F., Auregan, Guy, Muls, Vinciane, Cammaroto, Giovanni, Hans, Stéphane, Saussez, Sven, Lechien, Jérôme

المصدر: Clinical otolaryngology

مصطلحات موضوعية: Oto-rhino-laryngologie, apnea, impedance, laryngitis, laryngopharyngeal, obstructive, pH monitoring, pharyngeal, polysomnography, profile, reflux, reflux episode, sleep

وصف الملف: No full-text files

Relation: uri/info:doi/10.1111/coa.13745; uri/info:pmid/33621406; uri/info:scp/85106314576; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/324891

الاتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/324891

المؤلفون: Lechien, Jérôme, Bobin, F., Dequanter, Didier, Rodriguez, Alexandra, Le Bon, Serge-Daniel, Horoi, Mihaela, Thill, Marie Paule, Salem, Charelle, Muls, Vinciane, Saussez, Sven

المصدر: The Annals of otology, rhinology & laryngology

مصطلحات موضوعية: Oto-rhino-laryngologie, impedance, laryngitis, laryngopharyngeal, pepsin, pH monitoring, pharyngeal, profile, reflux, reflux episode, treatment

وصف الملف: No full-text files

Relation: uri/info:doi/10.1177/0003489420986347; uri/info:scp/85099766748; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/319058

الاتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/319058

المؤلفون: Charelle Salem, Sven Saussez, Vinciane Muls, Marie Paule Thill, Serge D Le Bon, Mihaela Horoi, Francois Bobin, Jerome R. Lechien, Didier Dequanter, Alexandra Rodriguez

المساهمون: Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil (UVSQ Santé), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Hôpital Foch [Suresnes], ELSAN-Polyclinique de Poitiers, CHU Saint-Pierre, Université libre de Bruxelles (ULB), Vesale Grant & IRIS-Recherche Grant (Foundation Roi Baudouin). The author(s) received no financial support for the research, authorship, and/or publication of this article.

المصدر: Annals of Otology Rhinology and Laryngology
Annals of Otology Rhinology and Laryngology, SAGE Publications, 2021, 130 (9), pp.996-1003. ⟨10.1177/0003489420986347⟩

مصطلحات موضوعية: Male, Saliva, Aluminum Hydroxide, Laryngitis, Gastroenterology, Laryngopharyngeal reflux, 0302 clinical medicine, Pepsin, [SHS.LANGUE]Humanities and Social Sciences/Linguistics, 030223 otorhinolaryngology, profile, biology, treatment, General Medicine, Hydrogen-Ion Concentration, Middle Aged, pharyngeal, Prognosis, 3. Good health, 030220 oncology & carcinogenesis, Female, Antacids, Adult, medicine.medical_specialty, Esophageal pH Monitoring, Magnesium Hydroxide, Alginates, reflux episode, Ph monitoring, 03 medical and health sciences, Esophagus, Internal medicine, medicine, Laryngopharyngeal Reflux, Humans, laryngitis, Aged, Monitoring, Physiologic, pepsin, business.industry, pH monitoring, Reflux, Proton Pump Inhibitors, medicine.disease, Pepsin A, laryngopharyngeal, Hypopharynx, Diagnostic Techniques, Digestive System, Otorhinolaryngology, impedance, biology.protein, reflux, business, Diet Therapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cadb72bd3bd7c9f9aba8efd8f7c73add
https://hal.archives-ouvertes.fr/hal-03401798

المؤلفون: Lechien, Jérôme, Bobin, F., Dapri, Giovanni, Eisendrath, Pierre, Salem, Charelle, Mouawad, Francois, Horoi, Mihaela, Thill, Marie Paule, Dequanter, Didier, Rodriguez, Alexandra, Muls, Vinciane, Saussez, Sven

المصدر: The Laryngoscope

مصطلحات موضوعية: Oto-rhino-laryngologie, impedance, laryngitis, Laryngopharyngeal, pepsin, pH monitoring, pharyngeal, profile, reflux, reflux episode, treatment

وصف الملف: No full-text files

Relation: uri/info:doi/10.1002/lary.28736; uri/info:scp/85085029556; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/307296

الاتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/307296

المصدر: Irish Journal of Medical Science

مصطلحات موضوعية: Berberine, Reflux Episode, Coeliac Disease, Olsalazine, Article, Omeprazole

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmc_________::666756a9e7a42f27bee0ea0824f7dba0
http://europepmc.org/articles/PMC7102237

المؤلفون: T. R. DeMeester, L. Bonavina

المساهمون: J.R. Siewert, A.H. Hölscher, T.R. Demeester, L. Bonavina

مصطلحات موضوعية: Gastroesophageal Reflux Disease, Reflux Episode, Acid Clearance, Persistent Dysphagia, Sphincter Length, Settore MED/18 - Chirurgia Generale

Relation: info:eu-repo/semantics/altIdentifier/isbn/9783642864346; ispartofbook:Diseases of the Esophagus; firstpage:1280; lastpage:1286; numberofpages:7; alleditors:J.R. Siewert, A.H. Hölscher; http://hdl.handle.net/2434/811581

الاتاحة: http://hdl.handle.net/2434/811581
https://doi.org/10.1007/978-3-642-86432-2_278