المؤلفون: Pfersdorf, Fabian, Romanazzi, Lucas, Rosenkilde, Mette Marie, Gustavsson, Martin

المصدر: Pfersdorf , F , Romanazzi , L , Rosenkilde , M M & Gustavsson , M 2025 , ' Regulation of the chemokine receptors CXCR4 and ACKR3 by receptor activity-modifying proteins ' , Journal of Biological Chemistry , vol. 301 , no. 1 , 108055 . https://doi.org/10.1016/j.jbc.2024.108055

مصطلحات موضوعية: ACKR3, arrestin recruitment, chemokine receptor, CXCL12, CXCR4, G protein-coupled receptor (GPCR), protein-protein interaction, receptor activity-modifying proteins (RAMPs), receptor internalization, signal transduction

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/regulation-of-the-chemokine-receptors-cxcr4-and-ackr3-by-receptor-activitymodifying-proteins(b585a4dd-6ecd-4eb9-8da4-a09c1e574c0d).html
https://doi.org/10.1016/j.jbc.2024.108055
https://curis.ku.dk/ws/files/422368814/Regulation_of_the_chemokine.pdf

المؤلفون: Harris, Matthew

المساهمون: Ladds, Graham

مصطلحات موضوعية: 572, GIPR, Pharmacology, Receptor activity-modifying proteins, Allosteric modulators

URL الوصول: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.805829

المؤلفون: Hiroshi Hosoda, Tsutomu Nakamura, Fumiki Yoshihara

المصدر: Biomolecules; Volume 12; Issue 9; Pages: 1281

مصطلحات موضوعية: adrenomedullin, plasma clearance, calcitonin receptor-like receptor, receptor activity modifying proteins, kidney

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Medicine; https://dx.doi.org/10.3390/biom12091281

الاتاحة: https://doi.org/10.3390/biom12091281

المؤلفون: Jean-Olivier Zirimwabagabo (1743481), Ameera B. A. Jailani (9165386), Paris Avgoustou (9165383), Matthew J. Tozer (2664976), Karl R. Gibson (1262118), Paul A. Glossop (1262115), James E. J. Mills (9165389), Roderick A. Porter (9165392), Paul Blaney (9165395), Ning Wang (108353), Timothy M. Skerry (8592216), Gareth O. Richards (9165410), Joseph P. A. Harrity (7204718)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Cancer, Inorganic Chemistry, Infectious Diseases, Computational Biology, Chemical Sciences not elsewhere classified, calcitonin receptor, CTR, RAMP, AM 2 receptors, compounds exhibit therapeutically, AM 2 antagonists, calcitonin receptor-like receptor, GPCR, receptor activity-modifying proteins, Optimization Class B G-protein-coup., CLR, AM 1 receptors, CGRP, first-in-class AM 2 receptor antago., AM 1 receptor

Relation: https://figshare.com/articles/online_resource/Discovery_of_a_First-In-Class_Small_Molecule_Antagonist_against_the_Adrenomedullin_2_Receptor_Structure_Activity_Relationships_and_Optimization/14365521

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c02191.ls01

المؤلفون: Kenny, Paraic A, Enver, Tariq, Ashworth, Alan

المصدر: BMC Cancer. 5(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Genetics, Biotechnology, Cancer, 2.1 Biological and endogenous factors, Aetiology, Animals, Blotting, Northern, Blotting, Western, Cell Line, Cytoskeletal Proteins, Epithelial Cells, Extracellular Matrix Proteins, Green Fluorescent Proteins, Humans, Intercellular Signaling Peptides and Proteins, Intracellular Signaling Peptides and Proteins, Lipopolysaccharide Receptors, Mammary Glands, Animal, Membrane Proteins, Mice, Multienzyme Complexes, Neoplasms, Oligonucleotide Array Sequence Analysis, Phosphodiesterase I, Phosphoric Diester Hydrolases, Pyrophosphatases, Receptor Activity-Modifying Protein 3, Receptor Activity-Modifying Proteins, Recombinant Fusion Proteins, Trans-Activators, Transcription Factors, Up-Regulation, Wnt Proteins, Wnt1 Protein, beta Catenin, Public Health and Health Services, Oncology & Carcinogenesis, Oncology and carcinogenesis, Epidemiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/18f4063q
https://escholarship.org/content/qt18f4063q/qt18f4063q.pdf

المؤلفون: Kirsten Raun, Linu M. John, Andrea Cabak, Soraya Arrigoni, Sofia Lundh, Christelle Le Foll, Thomas A. Lutz

المصدر: The European Journal of Neuroscience

مصطلحات موضوعية: Research Report, Calcitonin, Male, Agonist, obesity, medicine.medical_specialty, Rodent, medicine.drug_class, Amylin, Receptor Activity-Modifying Protein 3, Receptor Activity-Modifying Proteins, Receptor Activity-Modifying Protein 1, Eating, Mice, Weight loss, Internal medicine, biology.animal, medicine, Animals, animal, Receptor, agonist, Amylin Receptor Agonists, Receptor activity-modifying protein, RAMP, biology, Chemistry, General Neuroscience, Body Weight, Molecular and Synaptic Mechanisms, Receptors, Calcitonin, Islet Amyloid Polypeptide, Rats, Endocrinology, RAMP1, RAMP3, medicine.symptom, CTR

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9468a82a270a233da929391cd24c731a
https://doi.org/10.1111/ejn.15376

المؤلفون: Duncan I. Mackie, D. Stephen Serafin, Natalie R Harris, Natalie R Nielsen, Kathleen M. Caron

المصدر: Trends Pharmacol Sci

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, genetic structures, Calcitonin Gene-Related Peptide, musculoskeletal, neural, and ocular physiology, Computational biology, Biology, Antibodies, Monoclonal, Humanized, Toxicology, Receptor Activity-Modifying Proteins, Article, Receptors, G-Protein-Coupled, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Drug development, Calcitonin Gene-Related Peptide Receptor Antagonists, Mutation, Animals, Humans, Molecular Targeted Therapy, human activities, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325f47029b3f404d7328fceb00b68d30
https://doi.org/10.1016/j.tips.2020.01.009

المؤلفون: Emilia Díaz, Anthony Febres, Michelle Giammarresi, Adrian Silva, Oriana Vanegas, Carlos Gomes, Alicia Ponte-Sucre

المصدر: Frontiers in Cellular and Infection Microbiology. 12

مصطلحات موضوعية: Leishmania, Microbiology (medical), Infectious Diseases, Calcitonin Gene-Related Peptide, Immunology, Humans, Cell Communication, Substance P, Microbiology, Receptor Activity-Modifying Proteins, Receptors, G-Protein-Coupled

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b56c574c4f17fb92e959f326b49552ac
https://doi.org/10.3389/fcimb.2022.812848

المؤلفون: Suruchi Pacharne, Matthew Livesey, Mahita Kadmiel, Ning Wang, Kathleen M. Caron, Gareth O. Richards, Tim M. Skerry

المصدر: Frontiers in Endocrinology, Vol 12 (2022)
Frontiers in Endocrinology

مصطلحات موضوعية: Mice, Knockout, Endocrinology, Diabetes and Metabolism, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Receptor Activity-Modifying Protein 2, RC648-665, Receptor Activity-Modifying Protein 3, bone, osteoporosis, Receptor Activity-Modifying Proteins, Diseases of the endocrine glands. Clinical endocrinology, Receptor Activity-Modifying Protein 1, receptor activity modifying protein, Mice, endocrinology, ageing, Animals, Original Research

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a78455e93106f6bac818c21a705ea23d
https://doi.org/10.3389/fendo.2021.807882

المؤلفون: Alfonso Benítez-Páez, Sonia Cárdenas-Brito

المصدر: Evolutionary Bioinformatics, Vol 4, Pp 153-169 (2008)

مصطلحات موضوعية: Receptor Activity-Modifying Proteins, Functional divergence, Evolutionary history, Evolution, QH359-425

وصف الملف: electronic resource

Relation: http://la-press.com/article.php?article_id=756; https://doaj.org/toc/1176-9343

URL الوصول: https://doaj.org/article/e463cbe516ec4651b1306afb88b42a0d

المؤلفون: Weston, C., Lu, Jing, Li, Naichang, Barkan, K., Richards, G. O., Roberts, D. J., Skerry, T. M., Poyner, D., Pardamwar, M., Reynolds, C. A., Dowell, S. J., Willars, Gary Brian, Ladds, G.

مصطلحات موضوعية: G protein-coupled receptor (GPCR), glucagon, glucagon receptor, glucagon-like peptide-1, pharmacology, receptor activity-modifying proteins (RAMPs), signal bias, signal transduction, type 2 diabetes, Glucagon-Like Peptide-1 Receptor, HEK293 Cells, Humans, Ligands, Receptor Activity-Modifying Protein 2

Relation: http://www.ncbi.nlm.nih.gov/pubmed/26198634; Journal of Biological Chemistry, 2015, 290 (38), pp. 23009-23022; http://www.jbc.org/content/290/38/23009; http://hdl.handle.net/2381/36224; M114.624601

الاتاحة: http://www.jbc.org/content/290/38/23009
http://hdl.handle.net/2381/36224
https://doi.org/10.1074/jbc.M114.624601

المؤلفون: Min, Zhang, Li-Hua, Cheng, Xiao-Tong, Yin, Hao, Luo, Cheng, Cai

المصدر: Zhongguo Dang Dai Er Ke Za Zhi

مصطلحات موضوعية: Adrenomedullin, Experimental Research, Endothelial Cells, Humans, Lung Injury, Hyperoxia, Receptor Activity-Modifying Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::09329ce47bcecb60397a7daaa9310b9b
https://pubmed.ncbi.nlm.nih.gov/34911614

المؤلفون: Weston, Cathryn, Lu, Jing, Li, Naichang, Barkan, Kerry, Richards, Gareth O, Roberts, David J, Skerry, Timothy M, Poyner, David, Pardamwar, Meenakshi, Reynolds, Christopher A, Dowell, Simon J, Willars, Gary B, Ladds, Graham

مصطلحات موضوعية: G protein-coupled receptor (GPCR), glucagon, glucagon receptor, glucagon-like peptide-1, pharmacology, receptor activity-modifying proteins (RAMPs), signal bias, signal transduction, type 2 diabetes, Glucagon-Like Peptide-1 Receptor, HEK293 Cells, Humans, Ligands, Receptor Activity-Modifying Protein 2

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/249047

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/249047

المؤلفون: Matthew Harris, Duncan I. Mackie, Reema B. Davis, Kathleen M. Caron, Graham Ladds, Smriti Singh, Danica Dy, Natalie R Nielsen

المساهمون: Harris, Matthew [0000-0002-7918-5735], Ladds, Graham [0000-0001-7320-9612], Apollo - University of Cambridge Repository

المصدر: Proc Natl Acad Sci U S A

مصطلحات موضوعية: Bioluminescence Resonance Energy Transfer Techniques, Receptors, CCR3, Allosteric regulation, Neovascularization, Physiologic, chemokine receptors, Context (language use), Receptor Activity-Modifying Protein 3, Chemokine receptor, Cell Movement, Humans, Receptor, G protein-coupled receptor, Receptors, CXCR, Multidisciplinary, Receptor activity-modifying protein, G-protein–coupled receptors, Chemistry, guided cell migration, Chemotaxis, Biological Sciences, endosomal sorting, Cell biology, HEK293 Cells, Signal transduction, receptor-activity–modifying proteins, Lysosomes, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c83e944337cffd69f6c2bf29edf689a
https://doi.org/10.1073/pnas.1905561116

المؤلفون: Paolo Schiavini, André D.J. McKenzie, Michael Kassiou, Shane M. Wilkinson, Eryn L. Werry, Erick C.N. Wong, James O'Brien-Brown, Alexander Jackson, Alexandra Maximova

المصدر: European journal of pharmacology. 914

مصطلحات موضوعية: Pharmacology, Allosteric modulator, Purinergic P2X Receptor Antagonists, Chemistry, Activator (genetics), THP-1 Cells, Adamantane, Allosteric regulation, Antagonist, Porins, Receptor Activity-Modifying Proteins, chemistry.chemical_compound, Adenosine Triphosphate, HEK293 Cells, Drug Development, In vivo, Purinergic Agonists, Cathelicidins, Neuroinflammatory Diseases, Humans, Receptors, Purinergic P2X7, Guanidine, Receptor, Antimicrobial Cationic Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22dfa55719f76321560872c45c97ddb
https://pubmed.ncbi.nlm.nih.gov/34863711

المؤلفون: Nanqi Cui, Tsutomu Nakada, Yunlu Zhao, Hiroyuki Kawagishi, Takayuki Sakurai, Shinji Kakihara, Yuka Ichikawa-Shindo, Kohsuke Aruga, Yangxuan Wei, Hisaka Kawate, Takayuki Shindo, Akiko Kamiyoshi, Masaaki Tanaka, Mitsuhiko Yamada, Megumu Tanaka

المصدر: Endocrinology. 162(3)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Cardiac fibrosis, Cardiomegaly, Constriction, Pathologic, 030204 cardiovascular system & hematology, medicine.disease_cause, Receptor Activity-Modifying Protein 2, Cardiovascular System, Receptor Activity-Modifying Protein 3, Receptor Activity-Modifying Proteins, Muscle hypertrophy, 03 medical and health sciences, Adrenomedullin, Mice, 0302 clinical medicine, Endocrinology, Fibrosis, Stress, Physiological, Internal medicine, Medicine, Animals, Homeostasis, Myocytes, Cardiac, Cells, Cultured, Mice, Knockout, business.industry, Coronary Stenosis, Hemodynamics, medicine.disease, Oxidative Stress, 030104 developmental biology, Animals, Newborn, RAMP2, Heart failure, business, Oxidative stress, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7acdb68635bf3d4cd40a21da75147221
https://pubmed.ncbi.nlm.nih.gov/33545715

المؤلفون: Augen A. Pioszak, Debbie L. Hay

المصدر: Adv Pharmacol

مصطلحات موضوعية: Allosteric regulation, Amylin, Ligands, Receptor Activity-Modifying Proteins, Article, 03 medical and health sciences, Allosteric Regulation, Animals, Humans, Amino Acid Sequence, Calcitonin receptor, Receptor, G protein-coupled receptor, 0303 health sciences, Chemistry, musculoskeletal, neural, and ocular physiology, 030302 biochemistry & molecular biology, Calcitonin Receptor-Like Protein, Receptors, Calcitonin, Transmembrane protein, Cell biology, Adrenomedullin, Calcitonin, human activities, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be04d63555168b9230eba8031c4a3b97
https://pubmed.ncbi.nlm.nih.gov/32416865

المؤلفون: Megumu Tanaka, Akiko Kamiyoshi, Takayuki Sakurai, Akihiro Yamauchi, Yuka Ichikawa-Shindo, Takayuki Shindo, Hisaka Kawate

المصدر: Peptides. 111:55-61

مصطلحات موضوعية: medicine.medical_specialty, Physiology, 030209 endocrinology & metabolism, Calcitonin gene-related peptide, Receptor Activity-Modifying Protein 2, Receptor Activity-Modifying Protein 3, Biochemistry, Receptor Activity-Modifying Proteins, Adrenomedullin, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Endocrinology, Internal medicine, Animals, Homeostasis, Medicine, Receptor, Mice, Knockout, business.industry, Lymphatic system, RAMP2, Calcitonin, Circulatory system, Knockout mouse, business, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460a9d81cb4e046a9fd819a066f2db50
https://doi.org/10.1016/j.peptides.2018.04.004

المساهمون: Uludağ Üniversitesi/Tıp Fakültesi/Fizyoloji Anabilim Dalı., Çam, Betül Etöz, İşbil, Naciye Büyükcoşkun, Özlük, Kasım, AAH-1692-2021, 24179406800, 55665951400, 6602676331

مصطلحات موضوعية: Life sciences & biomedicine - other topics, Research & experimental medicine, Adrenomedullin, Blood pressure, Vasopressin, Atropine, Mecamylamine, Nervous-system, Blood-pressure, Receptors, Mechanisms, Peptide, Brain, Immunoreactivity, Acetylcholine, Involvement, Parameters, Rattus, Biology, Medicine, research & experimental, Adrenomedullin Receptors, Receptor Activity-Modifying Proteins, Calcitonin Receptor Like Receptor, (Beta mercapto beta beta cyclopentamethylenepropionyl1, o me tyrosine2,arginine8)vasopressin, Adrenomedullin[22-52], Calcitonin gene related peptide receptor, Calcitonin gene related peptide receptor antagonist, Calcitonin gene related peptide receptor[8-37]

وصف الملف: application/pdf

Relation: SBAG-105S508; Makale - Uluslararası Hakemli Dergi; Brazilian Journal of Medical and Biological Research; Çam, E. B. vd. (2012). "Cardiovascular effects of the intracerebroventricular injection of adrenomedullin: Roles of the peripheral vasopressin and central cholinergic systems". Brazilian Journal of Medical and Biological Research, 45(3), 250-255.; https://doi.org/10.1590/S0100-879X2012007500027; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854196/; http://hdl.handle.net/11452/26682; 000302556400011; 2-s2.0-84858427547; 250; 255; 45

الاتاحة: http://hdl.handle.net/11452/26682
https://doi.org/10.1590/S0100-879X2012007500027
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854196/

المؤلفون: Giuseppe, Bruschetta, Jung Dae, Kim, Sabrina, Diano, Li F, Chan

المساهمون: Bruschetta, Giuseppe, Kim, Jung Dae, Diano, Sabrina, Chan, Li F.

المصدر: Molecular Metabolism, Vol 18, Iss, Pp 79-87 (2018)
Molecular Metabolism

مصطلحات موضوعية: Male, lcsh:Internal medicine, MC4R, Diet, High-Fat, Receptor Activity-Modifying Proteins, Body Temperature, Eating, Mice, Food intake, Animals, Obesity, lcsh:RC31-1245, Molecular Biology, Adaptor Proteins, Signal Transducing, Neurons, MRAP2, digestive, oral, and skin physiology, Cell Biology, Mice, Inbred C57BL, Receptor, Melanocortin, Type 4, Female, Original Article, Energy homeostasis, Energy Metabolism, Energy homeostasi, Paraventricular Hypothalamic Nucleus

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0ca70f9c189a436fcf37b973b0843373
http://www.sciencedirect.com/science/article/pii/S2212877818307932