المؤلفون: Gioulbasani, Marianthi, Äijö, Tarmo, Liu, Siyao, Montgomery, Stephanie A., Montgomery, Nathan D., Corcoran, David, Tsagaratou, Ageliki

المصدر: Communications Biology, 7(1)

مصطلحات موضوعية: malignancy, DNA demethylation, TET family of proteins, Tet, expression, mice, genes, acquisition of malignant traits, protooncogene, traits, expansion, aberrant proliferation, acquisition, hematologic malignancies, gene expression, mutated genes, congenic mice, promoter DNA demethylation, translocation, suppressor, TET2, CD4 T cells, results, lymphoma, T cell expansion, aneuploidy, model, acquisition of aneuploidy, loss of genomic integrity, instability

Relation: https://cdr.lib.unc.edu/downloads/rb68xr95x?file=thumbnail; https://cdr.lib.unc.edu/downloads/rb68xr95x

الاتاحة: https://doi.org/10.17615/1rrt-s855
https://cdr.lib.unc.edu/downloads/rb68xr95x?file=thumbnail
https://cdr.lib.unc.edu/downloads/rb68xr95x

المؤلفون: Laura Vízkeleti, Sándor Spisák

المصدر: Cells, Vol 12, Iss 13, p 1745 (2023)

مصطلحات موضوعية: protooncogene, MYC deregulation, altered cellular metabolism, therapeutic targets, Cytology, QH573-671

Relation: https://www.mdpi.com/2073-4409/12/13/1745; https://doaj.org/toc/2073-4409; https://doaj.org/article/6c84e34c913d452db8e962c464500f41

الاتاحة: https://doi.org/10.3390/cells12131745
https://doaj.org/article/6c84e34c913d452db8e962c464500f41

المؤلفون: Karun Eadyow, Theerawut Phusantisampan, Wanwisa Maneechay, Surasak Sangkhathat

المصدر: Songklanakarin Journal of Science and Technology (SJST), Vol 42, Iss 3, Pp 596-601 (2020)

مصطلحات موضوعية: hirschsprung disease (hscr), ganglion cells, single nucleotide polymorphisms (snps), sox10, ret-protooncogene, Technology, Technology (General), T1-995, Science, Science (General), Q1-390

وصف الملف: electronic resource

Relation: https://rdo.psu.ac.th/sjstweb/journal/42-3/14.pdf; https://doaj.org/toc/0125-3395

URL الوصول: https://doaj.org/article/0cd83a8dda1c49cfb5164cfa7f7c0a85

المؤلفون: Liu, Yixin, Ribeiro, Orquidea De Castro, Haapanen, Outi, Craven, Gregory B., Sharma, Vivek, Muench, Stephen P., Goldman, Adrian

المساهمون: Molecular and Integrative Biosciences Research Programme, Materials Physics, Department of Physics, Institute of Biotechnology

مصطلحات موضوعية: ENDOCRINE NEOPLASIA TYPE-2, NEUROTROPHIC FACTOR, DISEASE PHENOTYPE, GLYCAN READER, CRYO-EM, RECEPTOR, GDNF, MUTATIONS, DYNAMICS, PROTOONCOGENE, Biochemistry, cell and molecular biology

وصف الملف: application/pdf

Relation: This work is supported by Instruct-ERIC (PID 12751 and 10661), the European Molecular Biology Organization short term fellowship (No. 8476), the Academy of Finland (No. 322609), the Academy of Finland (No. 286429), the Biotechnology and Biological Sciences Research Council (BBSRC, BB/M021610/1), the Academy of Finland (No. 294652), the Sigrid Juselius Foundation, the Jane and Aatos Erkko Foundation, and the Magnus Ehrnrooth Foundation.; Liu , Y , Ribeiro , O D C , Haapanen , O , Craven , G B , Sharma , V , Muench , S P & Goldman , A 2022 , ' Unexpected structures formed by the kinase RET C634R mutant extracellular domain suggest potential oncogenic mechanisms in MEN2A ' , Journal of Biological Chemistry , vol. 298 , no. 10 , 102380 . https://doi.org/10.1016/j.jbc.2022.102380; ORCID: /0000-0001-8032-9700/work/121693920; ORCID: /0000-0002-8838-3151/work/121699774; http://hdl.handle.net/10138/350306; e7991b22-6af0-49e8-ae71-2ba723646a1f; 000867425500010

الاتاحة: http://hdl.handle.net/10138/350306

المؤلفون: Jean G Bustamante Alvarez, Gregory A Otterson

المصدر: Drugs in Context, Vol 8, Pp 1-5 (2019)

مصطلحات موضوعية: dabrafenib, immunotherapy, lung neoplasm, protooncogene protein B-raf, trametinib, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://drugsincontext.com/agents-to-treat-braf-mutant-lung-cancer; https://doaj.org/toc/1740-4398

URL الوصول: https://doaj.org/article/73fa62dbc7764aacb0af967e59ef5db3

المؤلفون: Wistuba, II, Behrens, C, Albores Saavedra, J, Delgado, R, Lopez, F, Gazdar, AF

مصطلحات موضوعية: MICROSATELLITE INSTABILITY, DIFFERENTIAL ACTIVATION, CANCER, COLON, LUNG, PROTOONCOGENE, PATHOGENESIS, GENES, 03 Good Health and Well-being, 03 Salud y bienestar

وصف الملف: 5 páginas; application/pdf

Relation: MEDLINE:14506148; https://repositorio.uc.cl/handle/11534/79291; WOS:000185548300013

الاتاحة: https://repositorio.uc.cl/handle/11534/79291

المؤلفون: Masahide TAKAHASHI

المصدر: Proceedings of the Japan Academy, Series B. 2022, 98(3):112

المؤلفون: Bing Guan, Qing Li, Hui-Zhen Zhang, Hai-Sheng Yang

المصدر: Frontiers in Oncology, Vol 10 (2021)

مصطلحات موضوعية: basal-like breast carcinoma, circ_NOTCH3, circ_RNA, miR-205-5p, KLF12, protooncogene, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2020.602694/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/d340090e8b8a4e6c9fb6d22da05b9f11

المؤلفون: Le, T.L., Galmiche, L., Levy, J., Suwannarat, P., Hellebrekers, D.M., Morarach, K., Boismoreau, F., Theunissen, T.E.J., Lefebvre, M., Pelet, A., Martinovic, J., Gelot, A., Guimiot, F., Calleroz, A., Gitiaux, C., Hully, M., Goulet, O., Chardot, C., Drunat, S., Capri, Y., Bole-Feysot, C., Nitschke, P., Whalen, S., Mouthon, L., Babcock, H.E., Hofstra, R., de Coo, I.F.M., Tabet, A.C., Molina, T.J., Keren, B., Brooks, A., Smeets, H.J.M., Marklund, U., Gordon, C.T., Lyonnet, S., Amiel, J., Bondurand, N.

المصدر: Le , T L , Galmiche , L , Levy , J , Suwannarat , P , Hellebrekers , D M , Morarach , K , Boismoreau , F , Theunissen , T E J , Lefebvre , M , Pelet , A , Martinovic , J , Gelot , A , Guimiot , F , Calleroz , A , Gitiaux , C , Hully , M , Goulet , O , Chardot , C , Drunat , S , Capri , Y , Bole-Feysot , C , Nitschke , P , Whalen , S , Mouthon , L ....

مصطلحات موضوعية: CONGENITAL CONTRACTURAL SYNDROME, CHRONIC INTESTINAL PSEUDOOBSTRUCTION, SYNDROME TYPE-2 LCCS2, HIRSCHSPRUNG-DISEASE, SMOOTH-MUSCLE, PERIPHERAL NEUROPATHY, STRUCTURAL-ANALYSIS, RET PROTOONCOGENE, SOX10 MUTATIONS, TYROSINE KINASE

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/51075cd7-7aa8-46db-af1f-08d7e7441e5e
https://doi.org/10.1172/jci146389

المؤلفون: Postema, Floor A. M., Oosterwijk, Jan C., Hennekam, Raoul C.

المصدر: Postema , F A M , Oosterwijk , J C & Hennekam , R C 2021 , ' Genetic control of tumor development in malformation syndromes ' , American Journal of Medical Genetics. Part A , no. 2 , pp. 1-12 . https://doi.org/10.1002/ajmg.a.61947

مصطلحات موضوعية: cancer, CNVs, epigenetics, genetic compensation, mosaicism, tumor predisposition syndrome, COPY NUMBER, RET PROTOONCOGENE, MUTATIONS, SUPPRESSOR, PHENOTYPE, COMPENSATION, SURVEILLANCE, PATHOGENESIS

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/440f6d6b-e5d3-4f92-aa21-300d7dd0b59d
https://research.rug.nl/en/publications/440f6d6b-e5d3-4f92-aa21-300d7dd0b59d
https://doi.org/10.1002/ajmg.a.61947
https://pure.rug.nl/ws/files/150261910/Genetic_control_of_tumor_development_in_malformation_syndromes.pdf

المؤلفون: Kartal Baykan, Emine, Erdogan, Mehmet

مصطلحات موضوعية: C cell hyperplasia, Calcium, Medullary thyroid cancer, calcitonin, pentagastrin, cut-off, C-Cell Hyperplasia, Serum Calcitonin, Routine Measurement, Differential-Diagnosis, Ret Protooncogene, Plasma Calcitonin, Predictive-Value, Follow-Up, Carcinoma

Relation: Turkish Journal Of Medical Sciences; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://search.trdizin.gov.tr/yayin/detay/483911; https://doi.org/10.3906/sag-2003-182; https://hdl.handle.net/11454/78644; Kartal Baykan, Emine/0000-0001-6813-883X; 51; 650; 656

الاتاحة: https://hdl.handle.net/11454/78644
https://search.trdizin.gov.tr/yayin/detay/483911
https://doi.org/10.3906/sag-2003-182

المؤلفون: MB Horton, ED Hawkins, Susanne Heinzel, Philip Hodgkin

مصطلحات موضوعية: Uncategorized, Science & Technology, Life Sciences & Biomedicine, Cell Biology, Immunology, B cells, cell fate, cell signaling, comparative immunology, evolutionary immunology, humoral immunity, proliferation, VARIABLE LYMPHOCYTE RECEPTORS, GERMINAL CENTER, MYC, SELECTION, GENES, PROTOONCOGENE, ACTIVATION, EXPRESSION, DIVISION

Relation: https://figshare.com/articles/journal_contribution/Speculations_on_the_evolution_of_humoral_adaptive_immunity/13551536

الاتاحة: https://doi.org/10.26181/5ffb7b7012f5b
https://figshare.com/articles/journal_contribution/Speculations_on_the_evolution_of_humoral_adaptive_immunity/13551536

المؤلفون: Hirose, Hideki, Nakahara, Takehisa, Yonei, Shuji

المصدر: In Vitro Cellular & Developmental Biology. Animal, 2003 Sep 01. 39(8/9), 348-352.

URL الوصول: https://www.jstor.org/stable/4295484

المؤلفون: Maric, Christine, Machado, Raquel Pillar, de Buhr, Insa, Heringer-Walther, Silvia, Lopes, Myriam Teresa, Bader, Michael, Mendes, Elizabeth P., Lemos, Virgina Soares, Campagnole-Santos, Maria Jose, Schultheiss, Heinz-Peter, Speth, Robert, Walther, Thomas

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2003 Jul 01. 100(14), 8258-8263.

URL الوصول: https://www.jstor.org/stable/3139914

المؤلفون: Pfitzner, Edith, Kirfel, Jutta, Becker, Peter, Rolke, Andreas, Schule, Roland

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1998 May 01. 95(10), 5539-5544.

URL الوصول: https://www.jstor.org/stable/45121

المؤلفون: P. A. Skovorodnikova, M. S. Chesnokov, A. A. Budko, I. F. Kustova, N. L. Lazarevich

المصدر: Успехи молекулярной онкологии, Vol 4, Iss 2, Pp 36-45 (2017)

مصطلحات موضوعية: scaffold proteins, iqgap, multiprotein complex, map-kinase cascade, wnt signaling pathway, β-catenin, tumor progression, protooncogene, tumor suppressor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://umo.abvpress.ru/jour/article/view/93; https://doaj.org/toc/2313-805X; https://doaj.org/toc/2413-3787

URL الوصول: https://doaj.org/article/0dc2d7ff22d0422b8c3fda45e694da5c

المؤلفون: Russo, Alessandro, Cardona, Andrés F., Caglevic, Christian, Manca, Paolo, Ruiz-Patiño, Alejandro, Arrieta, Oscar, Rolfo, Christian

المصدر: 9 ; 6 ; 2581 ; 2598

مصطلحات موضوعية: Acquired resistance, Anaplastic lymphoma kinase (ALK), C-ros protooncogene 1 (ROS1), Neurotrophic tyrosine receptor kinases (NTRK), REarranged during Transfection (RET)

Relation: Translational Lung Cancer Research; http://hdl.handle.net/10713/14515

الاتاحة: http://hdl.handle.net/10713/14515
https://doi.org/10.21037/tlcr-2019-cnsclc-06

المؤلفون: Kyrklund, Kristiina, Sloots, Cornelius E. J., de Blaauw, Ivo, Bjornland, Kristin, Rolle, Udo, Cavalieri, Duccio, Francalanci, Paola, Fusaro, Fabio, Lemli, Annette, Schwarzer, Nicole, Fascetti-Leon, Francesco, Thapar, Nikhil, Johansen, Lars Sondergaard, Berrebi, Dominique, Hugot, Jean-Pierre, Cretolle, Celia, Brooks, Alice S., Hofstra, Robert M., Wester, Tomas, Pakarinen, Mikko P.

المساهمون: HUS Children and Adolescents, Clinicum, Children's Hospital, University of Helsinki, Helsinki University Hospital Area, Lastenkirurgian yksikkö

مصطلحات موضوعية: Rectosigmoid Hirschsprung's disease, HSCR, Diagnosis, Management, Follow-up, ENDORECTAL PULL-THROUGH, QUALITY-OF-LIFE, POSTOPERATIVE OBSTRUCTIVE SYMPTOMS, LONG-TERM OUTCOMES, RET PROTOONCOGENE, BOWEL FUNCTION, ANORECTAL MALFORMATION, COLOANAL ANASTOMOSIS, FECAL INCONTINENCE, BOTULINUM TOXIN, General medicine, internal medicine and other clinical medicine, Genetics, developmental biology, physiology

وصف الملف: application/pdf

Relation: Workgroup meetings and article-processing charges for open access publication in Orphanet Journal of Rare Diseases were supported by ERNICA European Reference Network. The authors have no other sources of funding to disclose.; Kyrklund , K , Sloots , C E J , de Blaauw , I , Bjornland , K , Rolle , U , Cavalieri , D , Francalanci , P , Fusaro , F , Lemli , A , Schwarzer , N , Fascetti-Leon , F , Thapar , N , Johansen , L S , Berrebi , D , Hugot , J-P , Cretolle , C , Brooks , A S , Hofstra , R M , Wester , T & Pakarinen , M P 2020 , ' ERNICA guidelines for the management of rectosigmoid Hirschsprung's disease ' , Orphanet journal of rare diseases , vol. 15 , no. 1 , 164 . https://doi.org/10.1186/s13023-020-01362-3; http://hdl.handle.net/10138/318402; 8e11d159-09ff-4145-86cc-b848870ab8ee; 000545598700001

الاتاحة: http://hdl.handle.net/10138/318402

المؤلفون: Yadav, Leena, Pietilä, Elina, Öhman, Tiina, Liu, Xiaonan, Mahato, Arun K., Sidorova, Yulia, Lehti, Kaisa, Saarma, Mart, Varjosalo, Markku

المساهمون: Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki, INDIVIDRUG - Individualized Drug Therapy, Kaisa Irene Lehti / Principal Investigator, Helsinki University Hospital Area, Genome-Scale Biology (GSB) Research Program, Research Programs Unit, Medicum, Mart Saarma / Principal Investigator, Molecular Systems Biology

مصطلحات موضوعية: PROTEIN-TYROSINE-PHOSPHATASE, RPTP-ALPHA, CATALYTIC DOMAINS, BINDING-SITE, RECEPTOR, ACTIVATION, PROTOONCOGENE, KINASE, PHOSPHORYLATION, IDENTIFICATION, Biochemistry, cell and molecular biology

وصف الملف: application/pdf

Relation: We acknowledge Sini Miettinen and Jenni Montonen for excellent technical assistance. This work was supported by grants from the Academy of Finland (Nos. 288475 and 294173), Sigrid Juselius Foundation (to M.V., K.L., and M.S.), Finnish Cancer Foundation (to M.V. and K.L.), University of Helsinki three-year research grant, Biocentrum Helsinki, Biocentrum Finland, and Instrumentarium Research Foundation.; Yadav , L , Pietilä , E , Öhman , T , Liu , X , Mahato , A K , Sidorova , Y , Lehti , K , Saarma , M & Varjosalo , M 2020 , ' PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential ' , iScience , vol. 23 , no. 2 , 100871 . https://doi.org/10.1016/j.isci.2020.100871; ORCID: /0000-0001-6647-8873/work/73629653; ORCID: /0000-0002-1340-9732/work/73631655; ORCID: /0000-0003-0209-9369/work/73634554; ORCID: /0000-0001-5543-7160/work/73634844; http://hdl.handle.net/10138/314696; c180e922-a472-47ff-a750-189f41392f9e; 000518637100051

الاتاحة: http://hdl.handle.net/10138/314696

المؤلفون: Larsen, Louise Volund, Mirebeau-Prunier, Delphine, Imai, Tsuneo, Alvarez-Escola, Cristina, Hasse-Lazar, Kornelia, Censi, Simona, Castroneves, Luciana A., Sakurai, Akihiro, Kihara, Minoru, Horiuchi, Kiyomi, Barbu, Veronique Dorine, Borson-Chazot, Francoise, Gimenez-Roqueplo, Anne-Paule, Pigny, Pascal, Pinson, Stephane, Wohllk, Nelson, Eng, Charis, Aydogan, Berna Imge, Saranath, Dhananjaya, Dvorakova, Sarka, Castinetti, Frederic, Patocs, Attila, Bergant, Damijan, Links, Thera P., Peczkowska, Mariola, Hoff, Ana O., Mian, Caterina, Dwight, Trisha, Jarzab, Barbara, Neumann, Hartmut P. H., Robledo, Mercedes, Uchino, Shinya, Barlier, Anne, Godballe, Christian, Mathiesen, Jes Sloth

المصدر: Larsen , L V , Mirebeau-Prunier , D , Imai , T , Alvarez-Escola , C , Hasse-Lazar , K , Censi , S , Castroneves , L A , Sakurai , A , Kihara , M , Horiuchi , K , Barbu , V D , Borson-Chazot , F , Gimenez-Roqueplo , A-P , Pigny , P , Pinson , S , Wohllk , N , Eng , C , Aydogan , B I , Saranath , D , Dvorakova , S , Castinetti , F , Patocs , A , Bergant , D , Links , T ....

مصطلحات موضوعية: primary hyperparathyroidism, multiple endocrine neoplasia type 2A, RET, medullary thyroid carcinoma, pheochromocytoma, MEDULLARY-THYROID CARCINOMA, RET PROTOONCOGENE, SURGICAL-MANAGEMENT, PROGNOSTIC-FACTORS, DISEASE PHENOTYPE, CODON 634, MEN 2A, MUTATIONS, PREVALENCE

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/03b60427-773f-4543-92b9-0d29968f11eb
https://research.rug.nl/en/publications/03b60427-773f-4543-92b9-0d29968f11eb
https://doi.org/10.1530/EC-20-0163
https://pure.rug.nl/ws/files/152978174/_20493614_Endocrine_Connections_Primary_hyperparathyroidism_as_first_manifestation_in_multiple_endocrine_neoplasia_type_2A_an_international_multicenter_study.pdf