المؤلفون: Colin T. Konishi, Nancy Mulaiese, Tanvi Butola, Qinkun Zhang, Dana Kagan, Qiaoyan Yang, Mariel Pressler, Brooke G. Dirvin, Orrin Devinsky, Jayeeta Basu, Chengzu Long

المصدر: Molecular Therapy: Nucleic Acids, Vol 36, Iss 1, Pp 102441- (2025)

مصطلحات موضوعية: MT: RNA/DNA Editing, protein conformational disease, protein aggregation, iPSC-derived neurons, CRISPR-Cas9, adenine base editing, Therapeutics. Pharmacology, RM1-950

Relation: http://www.sciencedirect.com/science/article/pii/S2162253124003287; https://doaj.org/toc/2162-2531; https://doaj.org/article/5c6dfcdaff0e453baf1051492517fc01

الاتاحة: https://doi.org/10.1016/j.omtn.2024.102441
https://doaj.org/article/5c6dfcdaff0e453baf1051492517fc01

المؤلفون: Yusa Nakamura, Kigen Takahashi

المصدر: Fishes, Vol 9, Iss 12, p 504 (2024)

مصطلحات موضوعية: Alaska pollock, protein conformational change, proteolysis, surimi, setting, water holding capacity, Biology (General), QH301-705.5, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2410-3888/9/12/504; https://doaj.org/toc/2410-3888

URL الوصول: https://doaj.org/article/215d2b0ee3b54ff798ca43b02e8658a8

المؤلفون: Andrei Izvolski, Aleksei Kuznetsov

المصدر: Proceedings of the Estonian Academy of Sciences, Vol 72, Iss 4, Pp 393-401 (2023)

مصطلحات موضوعية: protein kinase a, modeling of substrate binding, allosteric regulation of substrate binding, protein conformational dynamics, allostery mechanism, Science

وصف الملف: electronic resource

Relation: https://kirj.ee/wp-content/plugins/kirj/pub/proc-4-2023-393-401_20231116150735.pdf; https://doaj.org/toc/1736-6046; https://doaj.org/toc/1736-7530

URL الوصول: https://doaj.org/article/075e8ac017164d5093f9d853aee30a7b

المؤلفون: Sergey A. Silonov, Alexander I. Kuklin, Semen V. Nesterov, Irina M. Kuznetsova, Konstantin K. Turoverov, Alexander V. Fonin

المصدر: International Journal of Molecular Sciences ; Volume 25 ; Issue 24 ; Pages: 13600

مصطلحات موضوعية: macromolecular crowding, crowding agents, fluorescent hydrophobic dyes, ANS, protein conformational transitions, GdnHCl

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biochemistry; https://dx.doi.org/10.3390/ijms252413600

الاتاحة: https://doi.org/10.3390/ijms252413600

المؤلفون: Guido Izzi, Marco Campanile, Pompea Del Vecchio, Giuseppe Graziano

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 17, p 9360 (2024)

مصطلحات موضوعية: aspartate, glutamate, protein conformational stability, denaturants, counteraction, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/17/9360; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/e18c1420c79646bd8bd80f59db4ac623

الاتاحة: https://doi.org/10.3390/ijms25179360
https://doaj.org/article/e18c1420c79646bd8bd80f59db4ac623

المؤلفون: Xu Yi, Lichirui Zhang, Richard A. Friesner, Ann McDermott

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Infectious Diseases, Virology, Computational Biology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, single optimal conformations, significantly better agreement, picosecond time scale, n chemical shifts, >, protein conformational distributions, mm predicted shifts, 15 , sub ><, protein structure, predicted shifts, experimental shifts, variable temperatures, state nmr, shift variation, sensitive probe, representative snapshots, remain challenging, frozen solutions

Relation: https://figshare.com/articles/journal_contribution/Predicted_and_Experimental_NMR_Chemical_Shifts_at_Variable_Temperatures_The_Effect_of_Protein_Conformational_Dynamics/25262632

الاتاحة: https://doi.org/10.1021/acs.jpclett.3c02589.s002
https://figshare.com/articles/journal_contribution/Predicted_and_Experimental_NMR_Chemical_Shifts_at_Variable_Temperatures_The_Effect_of_Protein_Conformational_Dynamics/25262632

المؤلفون: Shriram Chennakesavalu, Grant M. Rotskoff

مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, Information Systems not elsewhere classified, “ backmapping ”, ubiquitous transformer architecture, generative neural networks, fundamentally different approach, dimensional sampling tasks, closely related problem, chain transformers excitement, biomolecular systems stems, protein structure prediction, maintains conformational diversity, unlike image generation, scalable physical simulation, parametrize generative models, driven generative models, building generative models, generate conformations based, chain conformations based, rapid data acquisition, largest data sets, protein conformational ensembles, fixed protein backbone, sample configurational ensembles

Relation: https://figshare.com/articles/journal_contribution/Data-Efficient_Generation_of_Protein_Conformational_Ensembles_with_Backbone-to-Side-Chain_Transformers/25282140

الاتاحة: https://doi.org/10.1021/acs.jpcb.3c08195.s001
https://figshare.com/articles/journal_contribution/Data-Efficient_Generation_of_Protein_Conformational_Ensembles_with_Backbone-to-Side-Chain_Transformers/25282140

المؤلفون: Honoka Kawamukai, Shumpei Takishita, Kazumi Shimizu, Daisuke Kohda, Koichiro Ishimori, Tomohide Saio

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Biotechnology, Hematology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, driven distribution shifts, distance distribution measurement, one possible strategy, targets dynamic proteins, intrinsically disordered proteins, visualizing conformational distribution, synthetic small molecules, solution structural biology, protein conformational studies, multidomain protein measured, conformational distribution, synthetic tag, pair small, including multidomain, important strategy, broad conformational, technical difficulties, target molecule, study used, study proposes, specific pair

Relation: https://figshare.com/articles/journal_contribution/Conformational_Distribution_of_a_Multidomain_Protein_Measured_by_Single-Pair_Small-Angle_X_ray_Scattering/24998302

الاتاحة: https://doi.org/10.1021/acs.jpclett.3c02600.s001
https://figshare.com/articles/journal_contribution/Conformational_Distribution_of_a_Multidomain_Protein_Measured_by_Single-Pair_Small-Angle_X_ray_Scattering/24998302

المؤلفون: André Hadad, Victor L. B. França, Marcos William Crisostomo, Kellen Brunaldi, Hernandes F. Carvalho, Valder N. Freire

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, transitional glom form, protein conformational clusters, human serum albumin, deeper fa7 cavity, glc ), keto, frc ), α, quantum biochemistry computations, quantum biochemistry analysis, various sugar forms, explaining gradual glycation, uncovering interaction energies, sarma , molecular dynamics reveal, molecular docking simulations, fro ), aldehydo, molecular dynamics, quantum aspects, sugar atoms, k195 glycation, analyze molecular

Relation: https://figshare.com/articles/journal_contribution/Unveiling_fructose_and_glucose_binding_to_human_serum_albumin_fluorescence_measurements_and_docking_molecular_dynamics_and_quantum_biochemistry_computations/25111240

الاتاحة: https://doi.org/10.6084/m9.figshare.25111240.v1
https://figshare.com/articles/journal_contribution/Unveiling_fructose_and_glucose_binding_to_human_serum_albumin_fluorescence_measurements_and_docking_molecular_dynamics_and_quantum_biochemistry_computations/25111240

المؤلفون: Ryan E. Odstrcil, Prashanta Dutta, Jin Liu

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, positively charged residues, closely packed cluster, nthl1 mutant demonstrates, stable ), closed, dna repair pathway, protein conformational changes, dna repair, conformational changes, unstable ), protein conformations, human nthl1, reaction coordinate, proteins rely, molecular mechanisms, many processes, linker could, genetic abnormalities, extremely challenging, enhanced sampling, better modulation

Relation: https://figshare.com/articles/journal_contribution/Enhanced_Sampling_for_Conformational_Changes_and_Molecular_Mechanisms_of_Human_NTHL1/25408368

الاتاحة: https://doi.org/10.1021/acs.jpclett.4c00161.s001

المؤلفون: Arvin Saffarian Delkhosh, Elaheh Hadadianpour, Md Majharul Islam, Elka R. Georgieva

المصدر: Journal of Structural Biology: X, Vol 11, Iss , Pp 100117- (2025)

مصطلحات موضوعية: Viral membrane proteins, Viroporins, Protein structure, Protein conformational dynamics, Viral protein-induced membrane permeability to ions, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590152424000229; https://doaj.org/toc/2590-1524

URL الوصول: https://doaj.org/article/34468992a4ef4caabfc4671499a8cb87

المؤلفون: Xiaozhao Wang, Cai Yao, Xudong Yao, Junxin Lin, Rui Li, Kun Huang, Weiming Lin, Xiaojun Long, Chao Dai, Jiajun Dong, Xuegong Yu, Wenwen Huang, Wenjian Weng, Qi Wang, Hongwei Ouyang, Kui Cheng

المصدر: Bioactive Materials, Vol 22, Iss , Pp 168-179 (2023)

مصطلحات موضوعية: Graphene, Protein conformational change, Charge transfer, Cell-materials interaction, n-doping, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2452199X22004182; https://doaj.org/toc/2452-199X

URL الوصول: https://doaj.org/article/ff4c723049884f81b9bdd6346fcbac6d

المؤلفون: Zhuang, Yuxuan, 1994

المساهمون: Lindahl, Erik, Professor, 1972, Brannigan, Grace, Associate Professor

مصطلحات موضوعية: ion channels, molecular dynamics, markov state model, lipid modulation, nicotinic receptor, protein conformational transitions, Biophysics, biofysik

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-220676
https://su.diva-portal.org/smash/get/diva2:1794307/FULLTEXT01.pdf
https://su.diva-portal.org/smash/get/diva2:1794307/PREVIEW01.jpg

المؤلفون: Bergh, Cathrine

المساهمون: Lindahl, Erik, Professor, Hummer, Gerhard, Professor

المصدر: TRITA-SCI-FOU.

مصطلحات موضوعية: Protein conformational transitions, molecular dynamics simulations, statistical mechanics, ion channels, Proteinkonformationsövergångar, molekyldynamiksimuleringar, statistisk mekanik, jonkanaler

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-326995
https://kth.diva-portal.org/smash/get/diva2:1757254/FULLTEXT01.pdf

المؤلفون: Hernández-Ibáñez, N., Montiel, V., Gomis-Berenguer, Alicia, Ania, C., Iniesta, J.

المصدر: Bioprocess and biosystems engineering (Print). 44(8):1699-1710

مصطلحات موضوعية: Carbon dioxide, Cytochrome c, Formate dehydrogenase hydrogen peroxide, Mesoporous carbon, Protein nanoconfinement, Candida, Carbon, Electron transport properties, Formic acid, Hydrogen peroxide, Pore size, Proteins, Reduction, Yeast, Direct electron transfer, Electro-activity, Electrochemical behaviour, Formate dehydrogenase, Nicotinamide adenine dinucleotides, Peroxidase activities, Protein conformational changes, Catalyst activity, heart enzyme, reduced nicotinamide adenine dinucleotide, nicotinamide adenine dinucleotide, biocatalyst, Candida boidinii, chronoamperometry, conformational transition, controlled study, cyclic voltammetry, electrochemical analysis, electron transport, enzyme activity, enzyme immobilization, horse, nonhuman, pH, pore size distribution, porosity, protein conformation, reduction (chemistry), surface area, synthesis, ultraviolet visible spectrophotometry, adsorption, animal, budding yeast, chemistry, electrochemistry, electrode, enzymology, kinetics, metabolism, statistical model, time factor, Animals, Cytochromes c, Electrodes, Formate Dehydrogenases, Formates, Horses, Hydrogen-Ion Concentration, Linear Models, NAD, Saccharomycetales, Time Factors

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-308505
https://doi.org/10.1007/s00449-021-02553-3

المؤلفون: Wodak, Shoshana J, Paci, Emanuele, Dokholyan, Nikolay V, Berezovsky, Igor N, Horovitz, Amnon, Li, Jing, Hilser, Vincent J, Bahar, Ivet, Karanicolas, John, Stock, Gerhard, Hamm, Peter, Stote, Roland H, Eberhardt, Jerome, Chebaro, Yassmine, Dejaegere, Annick, Cecchini, Marco, Changeux, Jean-Pierre, Bolhuis, Peter G, Vreede, Jocelyne, Faccioli, Pietro, Orioli, Simone, Ravasio, Riccardo, Yan, Le, Brito, Carolina, Wyart, Matthieu, Gkeka, Paraskevi, Rivalta, Ivan, Palermo, Giulia, McCammon, J Andrew, Panecka-Hofman, Joanna, Wade, Rebecca C, Di Pizio, Antonella, Niv, Masha Y, Nussinov, Ruth, Tsai, Chung-Jung, Jang, Hyunbum, Padhorny, Dzmitry, Kozakov, Dima, McLeish, Tom

المصدر: Structure. 27(4)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Generic health relevance, Allosteric Regulation, Allosteric Site, Animals, Biosensing Techniques, Drug Design, Gene Expression Regulation, Humans, Metabolic Networks and Pathways, Molecular Dynamics Simulation, Proteins, Signal Transduction, Thermodynamics, Transcription, Genetic, Allostery, allosteric drugs, allosteric material, allosteric switches, elastic network models, energy landscape, molecular dynamics, protein conformational changes, protein function, regulation, signal transduction, Chemical Sciences, Information and Computing Sciences, Biophysics, Biological sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1n3019zg
https://escholarship.org/content/qt1n3019zg/qt1n3019zg.pdf

المؤلفون: Buey, Rubén M, Fernández-Justel, David, de Pereda, José M, Revuelta, José L, Schürmann, Peter, Buchanan, Bob B, Balsera, Monica

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 115(51)

مصطلحات موضوعية: Clostridium acetobutylicum, Crystallography, X-Ray, Ferredoxins, Flavoproteins, Models, Molecular, NADP, Oxidation-Reduction, Protein Conformation, Sequence Analysis, Protein, Sequence Homology, flavoprotein, ferredoxin, protein conformational dynamics, redox-active disulfide, thioredoxin reductase

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9kd6f5w9

المؤلفون: Grasso, Daniela, Galderisi, Silvia, Santucci, Annalisa, Bernini, Andrea

المساهمون: Grasso, Daniela, Galderisi, Silvia, Santucci, Annalisa, Bernini, Andrea

مصطلحات موضوعية: computational structural biology, drug repurposing, molecular docking, pharmacological chaperone, pocket druggability, protein conformational disease, protein stability, transient pocket, virtual screening

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/36982893; info:eu-repo/semantics/altIdentifier/wos/WOS:000956759500001; volume:24; issue:6; numberofpages:26; journal:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; https://hdl.handle.net/11365/1233575; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85151087892; https://www.mdpi.com/1422-0067/24/6/5819; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054308/

الاتاحة: https://hdl.handle.net/11365/1233575
https://doi.org/10.3390/ijms24065819
https://www.mdpi.com/1422-0067/24/6/5819
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10054308/

المؤلفون: Intze, Antonia, Temperini, Maria Eleonora, Baldassarre, Leonetta, Giliberti, Valeria, Ortolani, Michele, Polito, Raffaella

المساهمون: Intze, Antonia, Temperini, Maria Eleonora, Baldassarre, Leonetta, Giliberti, Valeria, Ortolani, Michele, Polito, Raffaella

مصطلحات موضوعية: Bacteriorhodopsin (BR), protein conformational change, protein kinetics, time-resolved infrared spectroscopy, infrared laser micro-spectroscopy

Relation: volume:4; numberofpages:7; journal:FRONTIERS IN PHOTONICS; https://hdl.handle.net/11573/1679281

الاتاحة: https://hdl.handle.net/11573/1679281
https://doi.org/10.3389/fphot.2023.1175033

المؤلفون: Martin Vögele, Bin W. Zhang, Jonas Kaindl, Lingle Wang

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, thermodynamic principles suggest, proteins ’ functions, carefully designed restraints, eight g protein, corresponding conformational ensembles, binding free energy, binding free energies, various investigated receptors, important drug targets, protein conformational changes, particular functional response, binding thermodynamics provides, functional response, conformational equilibrium, strong binding, effective drug, coupled receptors, target protein, ligand binding, thoroughly validated, strong predictor, routinely calculated, receptor determined, prohibitively long

Relation: https://figshare.com/articles/journal_contribution/Is_the_Functional_Response_of_a_Receptor_Determined_by_the_Thermodynamics_of_Ligand_Binding_/24534663

الاتاحة: https://doi.org/10.1021/acs.jctc.3c00899.s001
https://figshare.com/articles/journal_contribution/Is_the_Functional_Response_of_a_Receptor_Determined_by_the_Thermodynamics_of_Ligand_Binding_/24534663