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المؤلفون: Düzel, Emrah, Thyrian, Jochen René
المصدر: Der Nervenarzt 94(5), 400-407 (2023). doi:10.1007/s00115-023-01478-4
مصطلحات موضوعية: Digital Technology, Cognition, Preventive measures, Interdisciplinary medicine, Risk reduction, Humans, ddc:610, Smartphone, Treatment concepts, prevention & control [Alzheimer Disease], Health competence, Mobile Applications
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المؤلفون: Forugh Salimi Dafsari, Frank Jessen
المصدر: Translational Psychiatry, Vol 10, Iss 1, Pp 1-13 (2020)
Translational Psychiatry 10(1), 160 (2020). doi:10.1038/s41398-020-0839-1
Translational Psychiatryمصطلحات موضوعية: medicine.medical_specialty, Review Article, Pathogenesis, Disease, prevention & control [Alzheimer Disease], Predictive markers, Prevention of dementia, prevention & control [Depression], lcsh:RC321-571, Cellular and Molecular Neuroscience, Alzheimer Disease, Risk Factors, Epidemiology, medicine, Dementia, Humans, Cognitive Dysfunction, ddc:610, Risk factor, Cognitive decline, Psychiatry, Life Style, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Biological Psychiatry, Depression (differential diagnoses), Depression, business.industry, Diagnostic markers, medicine.disease, Clinical trial, Psychiatry and Mental health, prevention & control [Cognitive Dysfunction], business
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3
المؤلفون: Paul S. Aisen, Robert Vassar, Pierre N. Tariot, Bart De Strooper, Colin L. Masters, Christian Haass, Randall J. Bateman, Stefan F. Lichtenthaler, Eric M. Reiman, Riqiang Yan, Iryna Voytyuk, Reisa A. Sperling, Maria C. Carrillo, Eric McDade
المصدر: Nature reviews / Neurology 17(11), 703-714 (2021). doi:10.1038/s41582-021-00545-1
مصطلحات موضوعية: Oncology, Male, genetics [Amyloid Precursor Protein Secretases], Plaque, Amyloid, antagonists & inhibitors [Amyloid Precursor Protein Secretases], prevention & control [Alzheimer Disease], APP protein, human, ALPHA-SECRETASE, Amyloid beta-Protein Precursor, metabolism [Amyloid beta-Protein Precursor], Amyloid precursor protein, BETA-SECRETASE, Aspartic Acid Endopeptidases, Enzyme Inhibitors, media_common, Aged, 80 and over, biology, SITE, antagonists & inhibitors [Aspartic Acid Endopeptidases], Middle Aged, AMYLOID PRECURSOR PROTEIN, VERUBECESTAT, therapeutic use [Enzyme Inhibitors], Research Design, Female, Alzheimer's disease, Life Sciences & Biomedicine, Drug, medicine.medical_specialty, media_common.quotation_subject, BACE1-AS, Clinical Neurology, MECHANISMS, Cellular and Molecular Neuroscience, Clinical Trials, Phase II as Topic, Alzheimer Disease, Internal medicine, BACE1 protein, human, medicine, Dementia, Humans, ddc:610, Adverse effect, Aged, Science & Technology, business.industry, CLEAVAGE, medicine.disease, RANDOMIZED-TRIAL, Clinical trial, prevention & control [Plaque, Amyloid], PATHOLOGY, Clinical Trials, Phase III as Topic, genetics [Aspartic Acid Endopeptidases], biology.protein, Neurology (clinical), Neurosciences & Neurology, MYELINATION, Amyloid Precursor Protein Secretases, business, Amyloid precursor protein secretase
وصف الملف: Print-Electronic
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المؤلفون: Frank Jessen, Giovanni B. Frisoni, Emmanuel Carrera, Wiesje M. van der Flier, Miia Kivipelto, Bruno Dubois, Jonathan M. Schott, Frederik Barkhof, Philip Scheltens, Bruno Vellas, Julien Delrieu, Daniele Altomare, Craig W. Ritchie, José Luis Molinuevo, Johannes Berkhof, Agneta Nordberg
المساهمون: Amsterdam Neuroscience - Neurodegeneration, Epidemiology and Data Science, APH - Methodology, Neurology, APH - Personalized Medicine, CCA - Imaging and biomarkers, CCA - Cancer biology and immunology, Radiology and nuclear medicine, Amsterdam Neuroscience - Brain Imaging, Amsterdam Neuroscience - Cellular & Molecular Mechanisms, Amsterdam Neuroscience - Neuroinfection & -inflammation, Epidemiology and biostatistics
المصدر: Alzheimer's and Dementia, 16(10), 1457-1468. Elsevier
Alzheimers & Dementia, 16(10), 1457-1468. Elsevier
Alzheimer's & Dementia, Vol. 16, No 10 (2020) pp. 1457-1468
Frisoni, G B, Molinuevo, J L, Altomare, D, Carrera, E, Berkhof, J, Delrieu, J, Dubois, B, Kivipelto, M, Nordberg, A, Schott, J M, van der Flier, W M, Vellas, B, Jessen, F, Scheltens, P & Ritchie, C 2020, ' Precision prevention of Alzheimer's and other dementias: Anticipating future needs in the control of risk factors and implementation of disease-modifying therapies ', Alzheimer's and Dementia, vol. 16, no. 10, pp. 1457-1468 . https://doi.org/10.1002/alz.12132
Alzheimer's and dementia 16(10), 1457-1468 (2020). doi:10.1002/alz.12132
NARCISمصطلحات موضوعية: Gerontology, Epidemiology, Control (management), Psychological intervention, MEDLINE, Disease, prevention & control [Alzheimer Disease], 03 medical and health sciences, Cellular and Molecular Neuroscience, ddc:616.89, 0302 clinical medicine, Developmental Neuroscience, Alzheimer Disease, Risk Factors, Secondary Prevention, Medicine, Dementia, Humans, 030212 general & internal medicine, ddc:610, Empirical evidence, business.industry, Health Policy, Incidence (epidemiology), Societal impact of nanotechnology, medicine.disease, prevention & control [Dementia], 3. Good health, methods [Primary Prevention], ddc:616.8, Primary Prevention, Psychiatry and Mental health, methods [Secondary Prevention], ddc:618.97, Neurology (clinical), Geriatrics and Gerontology, business, Risk Reduction Behavior, 030217 neurology & neurosurgery
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المؤلفون: Steffen Wolfsgruber, Debora Melo van Lent, Susanne Röhr, Luca Kleineidam, Michael Pentzek, Wolfgang Maier, Hans-Helmut König, Hendrik van den Bussche, Frank Jessen, Leonie Weinhold, Michael Wagner, Matthias Schmid, Birgitt Wiese, Siegfried Weyerer, Steffi G. Riedel-Heller, Karina Fischer, Marion Eisele, Horst Bickel, Martin Scherer
المصدر: Nutrients
Nutrients, Vol 10, Iss 7, p 852 (2018)
Nutrients 10(7), 852 (2018). doi:10.3390/nu10070852
Volume 10
Issue 7مصطلحات موضوعية: Male, memory decline, adverse effects [Food], psychology [Alzheimer Disease], Time Factors, food intake, epidemiology [Alzheimer Disease], Wine, psychology [Cognitive Aging], prevention & control [Alzheimer Disease], Neuropsychological Tests, Alzheimer´s dementia, 0302 clinical medicine, Cognition, Risk Factors, Germany, gender, 030212 general & internal medicine, Prospective Studies, apolipoprotein E ε4, Cognitive decline, Aged, 80 and over, Nutrition and Dietetics, Incidence (epidemiology), Incidence, diagnosis [Alzheimer Disease], Age Factors, food and beverages, Mental Status and Dementia Tests, Cohort, Red meat, Female, diagnosis [Memory Disorders], lcsh:Nutrition. Foods and food supply, epidemiology [Germany], lcsh:TX341-641, prevention & control [Memory Disorders], Article, 03 medical and health sciences, Sex Factors, Alzheimer Disease, Memory, medicine, Dementia, Humans, ddc:610, epidemiology [Memory Disorders], Geriatric Assessment, Aged, Memory Disorders, business.industry, Protective Factors, medicine.disease, cognitive decline, White Wine, Cognitive Aging, Food, psychology [Memory Disorders], Verbal memory, business, 030217 neurology & neurosurgery, Food Science, Demography, dementia
وصف الملف: application/pdf
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المؤلفون: Robert Perneczky
المساهمون: Perneczky, R
المصدر: New York, NY : Springer New York, Methods in Molecular Biology 1750, 15-29 (2018). doi:10.1007/978-1-4939-7704-8_2
Biomarkers for Alzheimer’s Disease Drug Development / Perneczky, Robert (Editor) ; New York, NY : Springer New York, 2018, Chapter 2 ; ISSN: 1064-3745=1940-6029 ; ISBN: 978-1-4939-7703-1=978-1-4939-7704-8 ; doi:10.1007/978-1-4939-7704-8
Biomarkers for Alzheimer’s Disease Drug Development ISBN: 9781493977031مصطلحات موضوعية: 0301 basic medicine, Gerontology, medicine.medical_specialty, epidemiology [Alzheimer Disease], Population, Drug development, genetics [Alzheimer Disease], Disease, Population based, Environment, Population-based, prevention & control [Alzheimer Disease], 0601 Biochemistry and Cell Biology, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Risk Factors, ddc:570, medicine, Genetics, Dementia, Humans, Genetic Predisposition to Disease, education, Preventive healthcare, education.field_of_study, business.industry, medicine.disease, Lifestyle, 030104 developmental biology, Cohort studies, Disease prevention, Preventive Medicine, Alzheimer's disease, business, Alzheimer’s disease, 030217 neurology & neurosurgery, Developmental Biology
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المؤلفون: Cox, Carla J., Choudhry, Fahd, Peacey, Eleanor, Perkinton, Michael S., Richardson, Jill C., Howlett, David R., Lichtenthaler, Stefan F., Francis, Paul T., Williams, Robert J.
المصدر: Neurobiology of Aging
Cox, C J, Choudhry, F, Peacey, E, Perkinton, M S, Richardson, J C, Howlett, D R, Lichtenthaler, S F, Francis, P T & Williams, R J 2015, ' Dietary (-)-epicatechin as a potent inhibitor of βγ-secretase amyloid precursor protein processing ', Neurobiology of Aging, vol. 36, no. 1, pp. 178-187 . https://doi.org/10.1016/j.neurobiolaging.2014.07.032
Neurobiology of aging 36(1), 178-187 (2015). doi:10.1016/j.neurobiolaging.2014.07.032مصطلحات موضوعية: Male, APP processing, Neuroscience(all), Clinical Neurology, metabolism [Amyloid beta-Peptides], administration & dosage [Catechin], Administration, Oral, genetics [Alzheimer Disease], Mice, Transgenic, prevention & control [Alzheimer Disease], Catechin, Pharmacology, Toxicology and Pharmaceutics(all), Amyloid beta-Protein Precursor, gallocatechol, Alzheimer Disease, metabolism [Amyloid beta-Protein Precursor], Animals, ddc:610, Amyloid pathology, Cells, Cultured, Aβ, Amyloid beta-Peptides, Biochemistry, Genetics and Molecular Biology(all), analogs & derivatives [Catechin], Brain, Regular Article, BACE1, Alzheimer's disease, Ageing, metabolism [Brain], Flavonoid, Dietary polyphenolic, Disease Progression, pharmacology [Catechin], Flavanol, Dementia, Geriatrics and Gerontology, TASTPM, Developmental Biology
وصف الملف: application/pdf
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المؤلفون: Bartels, Claudia, Wagner, Michael, Wolfsgruber, Steffen, Ehrenreich, Hannelore, Schneider, Anja, Initiative, Alzheimer’s Disease Neuroimaging
المصدر: The American journal of psychiatry 175(3), 232-241 (2018). doi:10.1176/appi.ajp.2017.17040404
مصطلحات موضوعية: 0301 basic medicine, drug therapy [Cognitive Dysfunction], medicine.medical_specialty, Serotonin reuptake inhibitor, etiology [Alzheimer Disease], Disease, Kaplan-Meier Estimate, Citalopram, prevention & control [Alzheimer Disease], behavioral disciplines and activities, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Risk Factors, mental disorders, complications [Depression], medicine, Humans, Alzheimer s dementia, Cognitive Dysfunction, ddc:610, drug therapy [Depression], Cognitive impairment, Psychiatry, Depression (differential diagnoses), Aged, Depression, therapeutic use [Selective Serotonin Reuptake Inhibitors], therapeutic use [Serotonin Uptake Inhibitors], 3. Good health, therapeutic use [Citalopram], Psychiatry and Mental health, 030104 developmental biology, Serotonin Uptake Inhibitors, Psychology, complications [Cognitive Dysfunction], 030217 neurology & neurosurgery, Geriatric psychiatry, Selective Serotonin Reuptake Inhibitors, medicine.drug, Alzheimer's Disease Neuroimaging Initiative
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المؤلفون: Sandrine Andrieu, Ara S. Khachaturian, Lon S. Schneider, Laura Fratiglioni, Edo Richard, Monique M.B. Breteler, Babak Hooshmand, Alina Solomon, David A. Bennett, Ingmar Skoog, Francesca Mangialasche, Miia Kivipelto
المساهمون: Neurology
المصدر: Journal of internal medicine, 275(3), 229-250. Wiley-Blackwell
Journal of Internal Medicine, 275, 229-50
Journal of Internal Medicine, 275, 3, pp. 229-50
Journal of internal medicine 275(3), 229-250 (2014). doi:10.1111/joim.12178مصطلحات موضوعية: Aging, medicine.medical_specialty, Population, Psychological intervention, Prodromal Symptoms, Disease, prevention & control [Alzheimer Disease], Article, Cognition, Alzheimer Disease, Risk Factors, Internal Medicine, medicine, Humans, Dementia, ddc:610, Longitudinal Studies, education, Psychiatry, Preventive healthcare, methods [Preventive Medicine], Clinical Trials as Topic, education.field_of_study, business.industry, Public health, diagnosis [Alzheimer Disease], complications [Alzheimer Disease], prevention & control [Dementia], Disorders of movement Donders Center for Medical Neuroscience [Radboudumc 3], medicine.disease, diagnosis [Dementia], Clinical trial, Early Diagnosis, Preventive Medicine, etiology [Dementia], Alzheimer's disease, analysis [Biomarkers], business, Biomarkers
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المؤلفون: Katharina Buerger, Dan Rujescu, Stefan J. Teipel, Verena C. Buschert, Harald Hampel, Sabrina Jolk, Ina Giegling
المصدر: The journal of clinical psychiatry 73(12), e1492-e1498 (2012). doi:10.4088/JCP.11m07270
مصطلحات موضوعية: Male, medicine.medical_specialty, psychology [Alzheimer Disease], epidemiology [Cognitive Dysfunction], Mental Status Schedule, epidemiology [Alzheimer Disease], medicine.medical_treatment, Prodromal Symptoms, prevention & control [Alzheimer Disease], Neuropsychological Tests, law.invention, Randomized controlled trial, Alzheimer Disease, law, Early Medical Intervention, Intervention (counseling), medicine, Humans, Dementia, therapy [Cognitive Dysfunction], Cognitive Dysfunction, ddc:610, Psychiatry, Aged, Cognitive Intervention, Cross-Over Studies, Cognitive Behavioral Therapy, diagnosis [Alzheimer Disease], Infant, Cognition, Middle Aged, medicine.disease, Combined Modality Therapy, Cognitive behavioral therapy, Psychiatry and Mental health, Early Diagnosis, diagnosis [Cognitive Dysfunction], Disease Progression, Cognitive therapy, Physical therapy, Female, psychology [Cognitive Dysfunction], Psychology, Computer-Assisted Instruction, Follow-Up Studies
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المؤلفون: Satish Kumar, Ulrike Krüger, Eva-Maria Mandelkow, Yipeng Wang
المصدر: Neurobiology of aging
Neurobiology of aging 33(10), 2291-2305 (2012). doi:10.1016/j.neurobiolaging.2011.11.009مصطلحات موضوعية: Aging, Tau protein, Mutant, tau Proteins, Endogeny, prevention & control [Alzheimer Disease], Mice, chemistry.chemical_compound, Alzheimer Disease, pharmacology [Trehalose], mental disorders, Autophagy, medicine, Animals, drug effects [Neurons], ddc:610, Phosphorylation, Cells, Cultured, Neurons, biology, General Neuroscience, Neurodegeneration, Trehalose, medicine.disease, N2a cell, metabolism [tau Proteins], Rats, Cell biology, chemistry, metabolism [Neurons], biology.protein, Neurology (clinical), Tauopathy, Geriatrics and Gerontology, metabolism [Alzheimer Disease], Developmental Biology
وصف الملف: application/pdf
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المؤلفون: Philip Scheltens, Kaj Blennow, Monique M B Breteler, Bart de Strooper, Giovanni B Frisoni, Stephen Salloway, Wiesje Maria Van der Flier
المساهمون: Neurology, Amsterdam Neuroscience - Neurodegeneration, Epidemiology and Data Science
المصدر: The lancet
388(10043), 505-517 (2016). doi:10.1016/S0140-6736(15)01124-1
Lancet, 388(10043), 505-517. Elsevier Limited
The Lancet, Vol. 388, No 10043 (2016) pp. 505-517
Scheltens, P, Blennow, K, Breteler, M M B, de Strooper, B, Frisoni, G B, Salloway, S & Van der Flier, W M 2016, ' Alzheimer's disease ', Lancet, vol. 388, no. 10043, pp. 505-517 . https://doi.org/10.1016/S0140-6736(15)01124-1مصطلحات موضوعية: Male, psychology [Alzheimer Disease], metabolism [Amyloid beta-Peptides], tau Proteins, prevention & control [Alzheimer Disease], Neuropsychological Tests, ddc:616.89, Cognition, pathology [Brain], Alzheimer Disease, Fluorodeoxyglucose F18, mental disorders, administration & dosage [Fluorodeoxyglucose F18], Humans, ddc:610, Aged, administration & dosage [Radiopharmaceuticals], Amyloid beta-Peptides, methods [Positron-Emission Tomography], diagnosis [Alzheimer Disease], Brain, General Medicine, Magnetic Resonance Imaging, metabolism [tau Proteins], metabolism [Brain], Positron-Emission Tomography, Female, Radiopharmaceuticals, Risk Reduction Behavior, metabolism [Alzheimer Disease], Biomarkers, metabolism [Biomarkers]
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المؤلفون: Koji Yamanaka, Jari Koistinaho, Douglas T. Golenbock, Terrence Town, Guy C. Brown, Erik Boddeke, Monica J. Carson, V. Hugh Perry, Gabor C. Petzold, Olga Garaschuk, David J. Brooks, Markus P. Kummer, John C.S. Breitner, Nikolaus Deigendesch, Frederic Brosseron, Greg M. Cole, Nicolas G. Bazan, Stéphane Hunot, Michael T. Heneka, Dave Morgan, Javier Vitorica, Gary E. Landreth, Clive Holmes, Eicke Latz, Bertrand Joseph, Annett Halle, Charles A. Dinarello, Mari L. Shinohara, Joseph El Khoury, Douglas L. Feinstein, Andreas H. Jacobs, Tony Wyss-Coray, Alexei Verkhratsky, Karl Herrup, Richard M. Ransohoff, Sally A. Frautschy, Bente Finsen
المصدر: The Lancet. Neurology, vol 14, iss 4
ResearcherID
The lancet/ Neurology 14(4), 388-405 (2015). doi:10.1016/S1474-4422(15)70016-5
Lancet Neurology, 14, 388-405
Heneka, MT; Carson, MJ; Khoury, JE; Landreth, GE; Brosseron, F; Feinstein, DL; et al.(2015). Neuroinflammation in Alzheimer's disease. The Lancet Neurology, 14(4), 388-405. doi: 10.1016/S1474-4422(15)70016-5. UCLA: Retrieved from: http://www.escholarship.org/uc/item/99h2f9m1
Lancet Neurology, 14, 4, pp. 388-405
Heneka, M T, Carson, M J, Khoury, J E, Landreth, G E, Brosseron, F, Feinstein, D L, Jacobs, A H, Wyss-Coray, T, Vitorica, J, Ransohoff, R M, Herrup, K, Frautschy, S A, Finsen, B, Brown, G C, Verkhratsky, A, Yamanaka, K, Koistinaho, J, Latz, E, Halle, A, Petzold, G C, Town, T, Morgan, D, Shinohara, M L, Perry, V H, Holmes, C, Bazan, N G, Brooks, D J, Hunot, S, Joseph, B, Deigendesch, N, Garaschuk, O, Boddeke, E, Dinarello, C A, Breitner, J C, Cole, G M, Golenbock, D T & Kummer, M P 2015, ' Neuroinflammation in Alzheimer's disease ', Lancet Neurology, vol. 14, no. 4, pp. 388-405 . https://doi.org/10.1016/S1474-4422(15)70016-5
The Lancet Neurologyمصطلحات موضوعية: Aging, MILD COGNITIVE IMPAIRMENT, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Disease, Alzheimer's Disease, Systemic inflammation, Severity of Illness Index, Inflammation/diagnosis, immunology [Inflammation], Aetiology, metabolism [Inflammation], blood [Biomarkers], Microglia, complications [Obesity], pathology [Microglia], RANDOMIZED CONTROLLED-TRIAL, immunology [Microglia], Disease Progression, Locus Coeruleus, Anti-Inflammatory Agents, Non-Steroidal/therapeutic use, Central nervous system, Clinical Sciences, CEREBRAL AMYLOID ANGIOPATHY, Article, administration & dosage [Nootropic Agents], Phagocytosis, Alzheimer Disease, Humans, Inflammation Mediators/immunology, NITRIC-OXIDE SYNTHASE, GENOME-WIDE ASSOCIATION, Locus Coeruleus/pathology, pathology [Locus Coeruleus], Animal, Prevention, Inflammatory and immune system, CENTRAL-NERVOUS-SYSTEM, Immunity, Immunity, Innate, diagnosis [Inflammation], immunology [Alzheimer Disease], nervous system, Astrocytes, Brain Injuries, Immunology, Dementia, Neurology (clinical), Obesity/complications, Neuroscience, Biomarkers, Protein Folding, Microglia/immunology, Anti-Inflammatory Agents, genetics [Alzheimer Disease], Neurodegenerative, prevention & control [Alzheimer Disease], pathology [Alzheimer Disease], Risk Factors, Brain Injuries/complications, complications [Brain Injuries], 2.1 Biological and endogenous factors, Innate, Nootropic Agents, therapeutic use [Anti-Inflammatory Agents, Non-Steroidal], pathology [Astrocytes], Clinical Trials as Topic, Nootropic Agents/administration & dosage, Anti-Inflammatory Agents, Non-Steroidal, Pattern recognition receptor, medicine.anatomical_structure, cerebrospinal fluid [Biomarkers], Neurological, medicine.symptom, Inflammation Mediators, immunology [Inflammation Mediators], Non-Steroidal, metabolism [Alzheimer Disease], Astrocytes/immunology, ANTIINFLAMMATORY PREVENTION TRIAL, TRAUMATIC BRAIN-INJURY, immunology [Astrocytes], metabolism [Brain Injuries], POSITRON-EMISSION-TOMOGRAPHY, metabolism [Obesity], Acquired Cognitive Impairment, medicine, Animals, ddc:610, Obesity, TRANSGENIC MOUSE MODEL, Neuroinflammation, Inflammation, Alzheimer Disease/genetics, Innate immune system, Neurology & Neurosurgery, business.industry, metabolism [Inflammation Mediators], Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Brain Disorders, Disease Models, Animal, Disease Models, Immunization, business, Biomarkers/blood
وصف الملف: application/pdf