المؤلفون: István Ledneczki, Zsolt Némethy, Katalin Dudásné Molnár, Pál Tapolcsányi, Viktor Ilkei, István Vágó, Sándor Kolok, Márta Thán, Judit Laszy, Ottilia Balázs, Balázs Krámos, Áron Szigetvári, Imre Bata, Attila Makó, András Visegrády, László Fodor, Mónika Vastag, György Lévay, Balázs Lendvai, István Greiner, János Éles

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Biotechnology, Sociology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, α7 nachrs appears, suboptimal metabolic stability, preclinical development candidate, induced amnesia test, improved metabolic stability, low kinetic solubility, 53 , kinetic solubility, vivo <, vitro <, viable approach, thorough modifications, promising results, positive modulation, pharmacological profile, new chemotype, lead series, high level, cognitive enhancement, balanced physicochemical, azetidinespirochromone family, also carried

Relation: https://figshare.com/articles/journal_contribution/Optimization_of_Novel_7_Nicotinic_Acetylcholine_Receptor_Positive_Allosteric_Modulators_and_the_Discovery_of_a_Preclinical_Development_Candidate_Molecule_RGH-560_/24602871

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01635.s002
https://figshare.com/articles/journal_contribution/Optimization_of_Novel_7_Nicotinic_Acetylcholine_Receptor_Positive_Allosteric_Modulators_and_the_Discovery_of_a_Preclinical_Development_Candidate_Molecule_RGH-560_/24602871

المؤلفون: István Ledneczki, Zsolt Némethy, Katalin Dudásné Molnár, Pál Tapolcsányi, Viktor Ilkei, István Vágó, Sándor Kolok, Márta Thán, Judit Laszy, Ottilia Balázs, Balázs Krámos, Áron Szigetvári, Imre Bata, Attila Makó, András Visegrády, László Fodor, Mónika Vastag, György Lévay, Balázs Lendvai, István Greiner, János Éles

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Biotechnology, Sociology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, α7 nachrs appears, suboptimal metabolic stability, preclinical development candidate, induced amnesia test, improved metabolic stability, low kinetic solubility, 53 , kinetic solubility, vivo <, vitro <, viable approach, thorough modifications, promising results, positive modulation, pharmacological profile, new chemotype, lead series, high level, cognitive enhancement, balanced physicochemical, azetidinespirochromone family, also carried

Relation: https://figshare.com/articles/dataset/Optimization_of_Novel_7_Nicotinic_Acetylcholine_Receptor_Positive_Allosteric_Modulators_and_the_Discovery_of_a_Preclinical_Development_Candidate_Molecule_RGH-560_/24602868

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01635.s001
https://figshare.com/articles/dataset/Optimization_of_Novel_7_Nicotinic_Acetylcholine_Receptor_Positive_Allosteric_Modulators_and_the_Discovery_of_a_Preclinical_Development_Candidate_Molecule_RGH-560_/24602868