المؤلفون: Haifeng Lu (465603), Shuxin Xu (1723963), Zhanchen Guo (6452771), Menghuan Zhao (11580423), Zhen Liu (74646)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Sociology, Cancer, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, ∼ 64 %), promote cells uptake, poor membrane permeability, maintain high stability, enhanced cell cytotoxicity, xenograft tumor model, overexpressed tumor cells, loaded therapeutic cargo, high therapeutic efficacy, rapid release kinetics, gsh ), resulting, targeted cancer therapy, hybridized silica nps, also permit redox, targeted intracellular delivery, cancer therapy, therapeutic intervention

Relation: https://figshare.com/articles/journal_contribution/Redox-Responsive_Molecularly_Imprinted_Nanoparticles_for_Targeted_Intracellular_Delivery_of_Protein_toward_Cancer_Therapy/16832178

الاتاحة: https://doi.org/10.1021/acsnano.1c07166.s001

المؤلفون: Xianqiang Li, Jinhuan Liu, Jinfeng Dou, Chao Li, Yongtao Jiang, Ali Dawood, Jie Wei, Yurong Wei, Youyi Xiong, Wanhe Luo, Samah Algharib

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Pharmacology, Space Science, Chemical Sciences not elsewhere classified, uniformly dispersed ellipse, staphylococcus aureus activity, significant inhibitory effect, potentially effective gelatinase, positively charged gelatin, poor membrane permeability, pharmaceutical properties provided, nanogels via interactions, nanogels exhibited gelatinase, fourier transform infrared, excellent sustained release, enhanced cellular delivery, cellular uptake efficiency, 4 ± 1, 3d network structure, responsive drug delivery, intracellular bacterial infection, 2 ± 2, 26 ± 0, 2 mv, responsive characteristics, intracellular bacteria, − 33, ζ potential

Relation: https://figshare.com/articles/journal_contribution/Enhanced_Cellular_Delivery_of_Tildipirosin_by_Xanthan_Gum_Gelatin_Composite_Nanogels/25282280

الاتاحة: https://doi.org/10.1021/acs.langmuir.3c03559.s001
https://figshare.com/articles/journal_contribution/Enhanced_Cellular_Delivery_of_Tildipirosin_by_Xanthan_Gum_Gelatin_Composite_Nanogels/25282280

المؤلفون: Justin H. Faris, Emel Adaligil, Nataliya Popovych, Satoshi Ono, Mifune Takahashi, Huy Nguyen, Emile Plise, Jaru Taechalertpaisarn, Hsiau-Wei Lee, Michael F. T. Koehler, Christian N. Cunningham, R. Scott Lokey

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, single methylene group, single amino acid, peptoid hybrid scaffolds, optimal lipophilicity range, mer cyclic peptide, macrocyclic peptides would, like chemical space, existing physicochemical knowledge, affinity macrocyclic peptides, dielectric conformation shifted, compounds described herein, classically undruggable targets, 200 macrocyclic 10, poor membrane permeability, passive membrane permeability, highly permeable scaffold, membrane permeability, shaped conformation, parent compounds, intracellular targets, cyclized 10, permeability could, achieving permeability, work provides

Relation: https://figshare.com/articles/journal_contribution/Membrane_Permeability_in_a_Large_Macrocyclic_Peptide_Driven_by_a_Saddle-Shaped_Conformation/25193926

الاتاحة: https://doi.org/10.1021/jacs.3c10949.s001

المؤلفون: Justin H. Faris, Emel Adaligil, Nataliya Popovych, Satoshi Ono, Mifune Takahashi, Huy Nguyen, Emile Plise, Jaru Taechalertpaisarn, Hsiau-Wei Lee, Michael F. T. Koehler, Christian N. Cunningham, R. Scott Lokey

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, single methylene group, single amino acid, peptoid hybrid scaffolds, optimal lipophilicity range, mer cyclic peptide, macrocyclic peptides would, like chemical space, existing physicochemical knowledge, affinity macrocyclic peptides, dielectric conformation shifted, compounds described herein, classically undruggable targets, 200 macrocyclic 10, poor membrane permeability, passive membrane permeability, highly permeable scaffold, membrane permeability, shaped conformation, parent compounds, intracellular targets, cyclized 10, permeability could, achieving permeability, work provides

Relation: https://figshare.com/articles/dataset/Membrane_Permeability_in_a_Large_Macrocyclic_Peptide_Driven_by_a_Saddle-Shaped_Conformation/25193929

الاتاحة: https://doi.org/10.1021/jacs.3c10949.s002
https://figshare.com/articles/dataset/Membrane_Permeability_in_a_Large_Macrocyclic_Peptide_Driven_by_a_Saddle-Shaped_Conformation/25193929

المؤلفون: Justin H. Faris, Emel Adaligil, Nataliya Popovych, Satoshi Ono, Mifune Takahashi, Huy Nguyen, Emile Plise, Jaru Taechalertpaisarn, Hsiau-Wei Lee, Michael F. T. Koehler, Christian N. Cunningham, R. Scott Lokey

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, single methylene group, single amino acid, peptoid hybrid scaffolds, optimal lipophilicity range, mer cyclic peptide, macrocyclic peptides would, like chemical space, existing physicochemical knowledge, affinity macrocyclic peptides, dielectric conformation shifted, compounds described herein, classically undruggable targets, 200 macrocyclic 10, poor membrane permeability, passive membrane permeability, highly permeable scaffold, membrane permeability, shaped conformation, parent compounds, intracellular targets, cyclized 10, permeability could, achieving permeability, work provides

Relation: https://figshare.com/articles/dataset/Membrane_Permeability_in_a_Large_Macrocyclic_Peptide_Driven_by_a_Saddle-Shaped_Conformation/25193929

الاتاحة: https://doi.org/10.1021/jacs.3c10949.s002