المؤلفون: Xuanjin Du, Chunyan Wang, Jialu Liu, Minghui Yu, Haixin Ju, Shanshan Xue, Yaxin Li, Jiaojiao Liu, Rufeng Dai, Jing Chen, Yihui Zhai, Jia Rao, Xiang Wang, Yubo Sun, Lei Sun, Xiaohui Wu, Hong Xu, Qian Shen

المصدر: Human Genomics, Vol 18, Iss 1, Pp 1-14 (2024)

مصطلحات موضوعية: Congenital anomalies of the kidney and urinary tract (CAKUT), GEN1 Holliday junction 5' flap endonuclease, Point-mutant mouse model, Human, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1479-7364

URL الوصول: https://doaj.org/article/a43175aa9be04788bf7778a84ec92ca0

المؤلفون: Musil Miloš, Jezik Andrej, Horáčková Jana, Borko Simeon, Kabourek Petr, Damborský Jiří, Bednář David

المصدر: Briefings in Bioinformatics

مصطلحات موضوعية: ancestral, back-to-consensus, B-factor, epistasis, evolution, force-field, multiple-point mutant, protein engineering, saturation mutagenesis, thermostability

Relation: https://is.muni.cz/publication/2349701

الاتاحة: https://is.muni.cz/publication/2349701
https://doi.org/10.1093/bib/bbad425

المؤلفون: Jianan Hu, Ruokui Chang, Yujin Yuan, Zhuoran Li, Yuanhong Wang

المصدر: Frontiers in Microbiology, Vol 13 (2022)

مصطلحات موضوعية: Bacillus velezensis LJ02, subtilisin point mutant, systemic acquired resistance, PAMP-triggered immunity, Botrytis cinerea, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2022.869596/full; https://doaj.org/toc/1664-302X

URL الوصول: https://doaj.org/article/c69763d502044d6783eba06a8789e010

المؤلفون: Braberg, Hannes, Moehle, Erica A, Shales, Michael, Guthrie, Christine, Krogan, Nevan J

المصدر: BioEssays. 36(7)

مصطلحات موضوعية: Biological Sciences, Genetics, Biotechnology, Underpinning research, 1.1 Normal biological development and functioning, Generic health relevance, Animals, Epistasis, Genetic, Gene Regulatory Networks, Genes, Humans, Point Mutation, Protein Binding, Protein Interaction Domains and Motifs, Protein Interaction Maps, E-MAP, genetic interactions, high-throughput, point mutant, RNA polymerase II, structure-function, yeast, Medical and Health Sciences, Psychology and Cognitive Sciences, Developmental Biology, Biological sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8dd6440h

المؤلفون: Dekang Zhu, Mingyu Zheng, Jinge Xu, Mingshu Wang, Renyong Jia, Shun Chen, Mafeng Liu, Xinxin Zhao, Qiao Yang, Ying Wu, Shaqiu Zhang, Juan Huang, Yunya Liu, Ling Zhang, Yanling Yu, Leichang Pan, Xiaoyue Chen, Anchun Cheng

المصدر: BMC Microbiology, Vol 19, Iss 1, Pp 1-8 (2019)

مصطلحات موضوعية: Riemerella anatipestifer, Fluoroquinolone resistance, Point mutant, gyrA gene, parC gene, parE gene, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1471-2180

URL الوصول: https://doaj.org/article/0cefc5b1b3ba44ab96cdb4e1e6e7d09e

المؤلفون: Iralis López-Villamizar, Alicia Cabezas, Rosa María Pinto, José Canales, João Meireles Ribeiro, Joaquim Rui Rodrigues, María Jesús Costas, José Carlos Cameselle

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 4; Pages: 1977

مصطلحات موضوعية: pathogen–host interaction, cyclic dinucleotide, extracytoplasmic phosphodiesterase, protein domain, truncated protein, point mutant, substrate-binding site, catalytic site, substrate specificity, inhibitor sensitivity

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Microbiology; https://dx.doi.org/10.3390/ijms22041977

الاتاحة: https://doi.org/10.3390/ijms22041977

المؤلفون: Gwi-woong Yoo, Cha-Gyun Shin

المصدر: BMB Reports, Vol 46, Iss 1, Pp 53-58 (2013)

مصطلحات موضوعية: Complementation reaction, Deletion mutant, Feline foamy virus, Integrase, Point mutant, Biology (General), QH301-705.5, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://bmbreports.org/jbmb/pdf.php?data=MTMwOTI2MTZAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0Ni0xJTVEMTMwMTI5MjExOV8lMjgwNTMtMDU4JTI5Qk1CXzEyLTExOC5wZGY=; https://doaj.org/toc/1976-6696; https://doaj.org/toc/1976-670X

URL الوصول: https://doaj.org/article/ac59629c9e32477e85a7904f005578e3

المؤلفون: Christian Widmann, Filip Stojceski, Pierre-Emmanuel Milhiet, Gabriel Ichim, Gianvito Grasso, Robyn Roth, Cédric Godefroy, Kushal Kumar Das, Andrea Danani, Marc Serulla, Tim Schober, Ana J. García-Sáez, Sergii Afonin, Mathieu Heulot

المساهمون: Milhiet, Pierre-Emmanuel, Université de Lausanne = University of Lausanne (UNIL), Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Istituto Dalle Molle di Studi sull'Intelligenza Artificiale (IDSIA), Università della Svizzera italiana = University of Italian Switzerland (USI)-Scuola universitaria professionale della Svizzera italiana = University of Applied Sciences and Arts of Southern Switzerland [Manno] (SUPSI), Karlsruhe Institute of Technology (KIT), Karlsruher Institut für Technologie (KIT), Washington University School of Medicine [Saint Louis, MO], Centre de Biochimie Structurale [Montpellier] (CBS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Eberhard Karls Universität Tübingen = Eberhard Karls University of Tuebingen, University of Lausanne (UNIL), Università della Svizzera italiana = University of Italian Switzerland (USI)-Scuola universitaria professionale della Svizzera italiana [Manno] (SUPSI), Washington University School of Medecine [Saint Louis, MO], Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM), Interfaculty Institute of Biochemistry (IFIB), University of Tübingen, 72076, Tübingen, Germany

المصدر: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2020, 117 (50), pp.31871-31881. ⟨10.1073/pnas.2014108117⟩
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2020, 117 (50), pp.31871-31881. ⟨10.1073/pnas.2014108117⟩

مصطلحات موضوعية: Phosphatidylinositol 4,5-Diphosphate, 0301 basic medicine, Programmed cell death, Necrosis, [SDV.BBM.BP] Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biophysics, Peptide, CHO Cells, Phosphatidylserines, Molecular Dynamics Simulation, 03 medical and health sciences, chemistry.chemical_compound, Cricetulus, 0302 clinical medicine, Neoplasms, medicine, Animals, Humans, Nuclear Magnetic Resonance, Biomolecular, chemistry.chemical_classification, Multidisciplinary, Cell Death, Chemistry, Cell Membrane, GTPase-Activating Proteins, Phosphatidylserine, Biological Sciences, Peptide Fragments, Cell biology, Point mutant, [SDV.BBM.BP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biophysics, Microscopy, Electron, Cytosol, 030104 developmental biology, Membrane, 030220 oncology & carcinogenesis, Liposomes, Cancer cell, lipids (amino acids, peptides, and proteins), medicine.symptom, HeLa Cells

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34b26f0b4c3c018a1b1ed8e632f43982
https://doi.org/10.1073/pnas.2014108117

المؤلفون: Jeffrey K. Moore, Gabriella Li

المصدر: Molecular Biology of the Cell

مصطلحات موضوعية: Saccharomyces cerevisiae Proteins, Microtubule dynamics, Arabidopsis, Nucleation, Saccharomyces cerevisiae, Plasma protein binding, Microtubules, Polymerization, Tubulin, Microtubule, Molecular Biology, Cytoskeleton, biology, Arabidopsis Proteins, Depolymerization, Temperature, Articles, Cell Biology, Point mutant, Cold Temperature, Carbon-Sulfur Lyases, Biophysics, biology.protein, Microtubule-Associated Proteins, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::311964208e00eca97536767b19894605
https://doi.org/10.1091/mbc.e19-11-0634

المؤلفون: Jianan Hu, Ruokui Chang, Yujin Yuan, Zhuoran Li, Yuanhong Wang

مصطلحات موضوعية: Microbiology, Microbial Genetics, Microbial Ecology, Mycology, Bacillus velezensis LJ02, subtilisin point mutant, systemic acquired resistance, PAMP-triggered immunity, Botrytis cinerea

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Identification_of_Key_Residues_Essential_for_the_Activation_of_Plant_Immunity_by_Subtilisin_From_Bacillus_velezensis_LJ02_docx/20487951

الاتاحة: https://doi.org/10.3389/fmicb.2022.869596.s001
https://figshare.com/articles/dataset/Data_Sheet_1_Identification_of_Key_Residues_Essential_for_the_Activation_of_Plant_Immunity_by_Subtilisin_From_Bacillus_velezensis_LJ02_docx/20487951

المؤلفون: Gross, Mary K., Au, Douglas C., Smith, Arnold L., Storm, Daniel R.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1992 Jun 01. 89(11), 4898-4902.

URL الوصول: https://www.jstor.org/stable/2359554

المؤلفون: Joaquim Rui Rodrigues, María Jesús Costas, José Carlos Cameselle, Alicia Cabezas, Iralis López-Villamizar, José Canales, João Meireles Ribeiro, Rosa María Pinto

المصدر: International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1977, p 1977 (2021)

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Adenosine, substrate specificity, medicine.disease_cause, cyclic dinucleotide, lcsh:Chemistry, Catalytic Domain, lcsh:QH301-705.5, Spectroscopy, chemistry.chemical_classification, Cyclic nucleotide phosphodiesterase, Escherichia coli Proteins, Hydrolysis, protein domain, General Medicine, Computer Science Applications, substrate-binding site, Biochemistry, 2',3'-Cyclic-Nucleotide Phosphodiesterases, inhibitor sensitivity, medicine.drug, truncated protein, Protein domain, point mutant, Catalysis, Article, Phosphates, Inorganic Chemistry, Structure-Activity Relationship, 03 medical and health sciences, Protein Domains, Nucleotidase, Escherichia coli, medicine, Point Mutation, Histidine, Physical and Theoretical Chemistry, Binding site, Molecular Biology, pathogen–host interaction, Binding Sites, 030102 biochemistry & molecular biology, Organic Chemistry, Periplasmic space, catalytic site, Kinetics, 030104 developmental biology, Enzyme, lcsh:Biology (General), lcsh:QD1-999, chemistry, Biocatalysis, extracytoplasmic phosphodiesterase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686a63b1d444b03152a49fc2a92b492a
http://europepmc.org/articles/PMC7922932

المؤلفون: Seung-Joo Lee, Gregory L. Verdine, Mcgee John Hanney, So Youn Shim, Paige K. Swanson, Michael A. Durney, Sam Y. Jiang

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Plasma protein binding, 010402 general chemistry, 01 natural sciences, Biochemistry, 03 medical and health sciences, Protein Domains, Signaling proteins, Drug Discovery, cancer, Amino Acid Sequence, directed evolution, Databases, Protein, Protein Structure, Quaternary, Molecular Biology, X-ray crystallography, Chemistry, Effector, Proteins, Cell Biology, Directed evolution, 0104 chemical sciences, Structure and function, Point mutant, Cell biology, 030104 developmental biology, Mutation, Protein Structure and Folding, ras Proteins, peptides, Protein Multimerization, Ras protein, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c823f69808dd9f4fe65d277cac9c472
https://doi.org/10.1074/jbc.m117.816348

المؤلفون: Fujimoto Kengo, Inaba Akemi, Tomomura Akito, Katoh Setsuko

المصدر: Pteridines, Vol 11, Iss 3, Pp 81-82 (2000)

مصطلحات موضوعية: sepiapterin reductase, phosphorylation site, ca2+-dependent protein kinase ii, point mutant, Crystallography, QD901-999

Relation: https://doi.org/10.1515/pteridines.2000.11.3.81; https://doaj.org/toc/0933-4807; https://doaj.org/toc/2195-4720; https://doaj.org/article/0b293ab0ff8549d88726c8002177d776

الاتاحة: https://doi.org/10.1515/pteridines.2000.11.3.81
https://doaj.org/article/0b293ab0ff8549d88726c8002177d776

المؤلفون: Jason N. Berman, Sergey V. Prykhozhij

المصدر: Disease Models & Mechanisms, Vol 11, Iss 10 (2018)
Disease Models & Mechanisms

مصطلحات موضوعية: 0301 basic medicine, Computer science, ved/biology.organism_classification_rank.species, Neuroscience (miscellaneous), Medicine (miscellaneous), lcsh:Medicine, Computational biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Immunology and Microbiology (miscellaneous), Genome editing, Point mutations, lcsh:Pathology, CRISPR, Animals, Point Mutation, Gene Knock-In Techniques, Model organism, Zebrafish, CRISPR/Cas9, biology, ved/biology, Cas9, lcsh:R, Identifying problems, biology.organism_classification, Point mutant, Disease Models, Animal, 030104 developmental biology, Editorial, Mutation (genetic algorithm), CRISPR-Cas Systems, lcsh:RB1-214

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4104533d6f3b2b252b6a63771450e9
http://dmm.biologists.org/content/11/10/dmm037515

المؤلفون: Jeetain Mittal, Gül H. Zerze, Bilge Uz

المصدر: Proteins: Structure, Function, and Bioinformatics. 83:1307-1315

مصطلحات موضوعية: chemistry.chemical_classification, Replica, Ab initio, Thermodynamics, Peptide, Biochemistry, Force field (chemistry), Point mutant, Molecular dynamics, chemistry, Structural Biology, Free energies, Protein folding, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::888f2e0f9fe1fcde3c9dfb69a58bf7a4
https://doi.org/10.1002/prot.24827

المؤلفون: Chaloupkova, Radka, Musil, Milos, Stourac, Jan, Bendl, Jaroslav, Brezovsky, Jan, Prokop, Zbynek, Martinek, Tomas, Bednar, David

المصدر: Enzyme Engineering XXIV

مصطلحات موضوعية: evolutionary analysis, energetic analysis, multiple-point mutant, stability, web server, Engineering

Relation: https://dc.engconfintl.org/enzyme_xxiv/11

الاتاحة: https://dc.engconfintl.org/enzyme_xxiv/11

المؤلفون: Rachel W. Martin, William D. Brubaker

المصدر: Biomolecular NMR Assignments. 6:63-67

مصطلحات موضوعية: genetic structures, Chemistry, Wild type, Cataract formation, Protein aggregation, Biochemistry, eye diseases, Point mutant, Crystallography, Protein structure, Structural Biology, Crystallin, sense organs, Eye lens, Peptide sequence

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::21225546116c7aeb41dc2f7624eba176
https://doi.org/10.1007/s12104-011-9326-1

المؤلفون: Brajendra K. Tripathi, Marian E. Durkin, Beatriz Sánchez-Solana, Xiaolan Qian, Dunrui Wang, Douglas R. Lowy, Alex G. Papageorge

المصدر: Cancer Research. 78:5522-5522

مصطلحات موضوعية: Cancer Research, Rho GAP activity, PLCD1, Chemistry, Cancer, medicine.disease, Point mutant, Cell biology, Oncology, Domain (ring theory), Caveolin 1, medicine, Tumor suppressor activity, DLC1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a458602b78286dbd7164c73aafc9d899
https://doi.org/10.1158/1538-7445.am2018-5522

المؤلفون: Asli Oztan, Gerard Apodaca, James R. Goldenring, Lynne A. Lapierre, Janice A. Williams, Nicole A. Ducharme

المصدر: American Journal of Physiology-Cell Physiology. 293:C1059-C1072

مصطلحات موضوعية: Physiology, Endosome, Green Fluorescent Proteins, Vesicular Transport Proteins, Endosomes, Biology, Microtubules, Cell Line, EEA1, Dogs, Animals, Humans, Point Mutation, Differentiable function, Genes, Dominant, Early endosome, Cell Polarity, Membrane Proteins, Epithelial Cells, Cell Biology, Point mutant, Cell biology, Rab11-FIP2, Microscopy, Electron, Protein Transport, Kidney Tubules, Transcytosis, rab GTP-Binding Proteins, Mutagenesis, Site-Directed, Carrier Proteins, RAB11A

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebf146628ebfe98c8ece52babbc2382
https://doi.org/10.1152/ajpcell.00078.2007