المؤلفون: Anna Tochowicz, Klaus Richter, Hideaki Nagase, Wolfram Bode, Robert Visse, Klaus Maskos, Richard Evans, Peter Goettig, Noriko Ito, Yoshifumi Itoh, Daniel Franke, Ralf Palmisano, Yasuyuki Shitomi, Dmitri I. Svergun

المصدر: The journal of biological chemistry 286, 7587-7600 (2011). doi:10.1074/jbc.M110.178434
The Journal of Biological Chemistry

مصطلحات موضوعية: Dimer, Matrix (biology), Matrix metalloproteinase, Biochemistry, chemistry.chemical_compound, 0302 clinical medicine, Protein structure, Hemopexin, Chlorocebus aethiops, 0303 health sciences, Crystallography, metabolism [Matrix Metalloproteinase 14], Chemistry, MMP14 protein, human, Extracellular Matrix, genetics [Membrane Proteins], physiology [Enzyme Activation], chemistry [Matrix Metalloproteinase 14], 030220 oncology & carcinogenesis, COS Cells, Dimerization, chemistry [Hemopexin], Cell Surface Enzymes, Stereochemistry, enzymology [Extracellular Matrix], Cell Migration, genetics [Matrix Metalloproteinase 14], genetics [Hemopexin], Cercopithecus aethiops, Structure-Activity Relationship, 03 medical and health sciences, ddc:570, Hydrolase, Matrix Metalloproteinase 14, Animals, Humans, Structure–activity relationship, chemistry [Membrane Proteins], Matrix Metalloproteinase, Molecular Biology, 030304 developmental biology, Membrane Proteins, Cell Biology, Protease, Protein Structure, Tertiary, Enzyme Activation, Solubility, Membrane protein, Mutagenesis, Enzymology, metabolism [Hemopexin], metabolism [Membrane Proteins], HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326609ab62d10c9d41e7d089cdcb19c8
https://doi.org/10.1074/jbc.m110.178434

المؤلفون: Houfen Su, Anshu Agrawal, Sudhir Gupta, Kathryn Osann, Sudhanshu Agrawal, Justine Chen

المصدر: Agrawal, Anshu; Su, Houfen; Chen, Justine; Osann, Kathryn; Agrawal, Sudhanshu; & Gupta, Sudhir. (2012). Increased IL-21 secretion by aged CD4+T cells is associated with prolonged STAT-4 activation and CMV seropositivity.. Aging, 4(9), 648-659. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/0mk1j4qf
Aging (Albany NY)

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, Aging, Cellular differentiation, immunology [Dendritic Cells], Cytomegalovirus, Priming (immunology), Stimulation, Lymphocyte Activation, immunology [Lymphocyte Activation], IL-21, Medicine and Health Sciences, cytology, immunology, metabolism, secretion [CD4-Positive T-Lymphocytes], Cells, Cultured, Aged, 80 and over, biology, Interleukin, Cell Differentiation, STAT4 Transcription Factor, immunology [Cytomegalovirus Infections], immunology [Aging], physiology [Enzyme Activation], Cytomegalovirus Infections, Female, Antibody, medicine.symptom, Research Paper, Adult, medicine.medical_specialty, Inflammation, Enzyme-Linked Immunosorbent Assay, Young Adult, Immune system, immunology [Cell Differentiation], Internal medicine, medicine, Humans, Secretion, Aged, secretion [Interleukins], Interleukins, Dendritic Cells, Cell Biology, metabolism [STAT4 Transcription Factor], CD4+ T cells, Coculture Techniques, Enzyme Activation, Endocrinology, Immunology, biology.protein, T follicular helper cells, STAT-4

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c99670740025367ee68c54ec1a0b522b
http://www.escholarship.org/uc/item/0mk1j4qf

المؤلفون: Velichka Stoycheva, Daniela Berg, Walter Maetzler, Kathrin Brockmann, Arthur Melms, Benjamin Schmid, Claudia Schulte, Thomas Gasser, Ann-Kathrin Hauser

المصدر: Journal of Alzheimer's disease 22(3), 933-938 (2010). doi:10.3233/JAD-2010-101197

مصطلحات موضوعية: Male, enzymology [Dementia], cerebrospinal fluid [Neprilysin], cerebrospinal fluid [Amyloid beta-Peptides], cerebrospinal fluid [Lewy Body Disease], Disease, Cohort Studies, Cerebrospinal fluid, physiology [Peptide Fragments], Medicine, Neprilysin, Aged, 80 and over, cerebrospinal fluid [Dementia], General Neuroscience, General Medicine, Middle Aged, amyloid beta-protein (1-42), Psychiatry and Mental health, Clinical Psychology, physiology [Enzyme Activation], cerebrospinal fluid [Biomarkers], physiology [Amyloid beta-Peptides], psychology [Lewy Body Disease], Female, Lewy Body Disease, medicine.medical_specialty, enzymology [Lewy Body Disease], Neurite, Amyloid, psychology [Dementia], Internal medicine, Dementia, Humans, ddc:610, cerebrospinal fluid [Peptide Fragments], Aged, Amyloid beta-Peptides, business.industry, fungi, medicine.disease, Peptide Fragments, Enzyme Activation, Neprilysin activity, Endocrinology, Geriatrics and Gerontology, business, Lewy body disease, Neuroscience, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457c16cbbcdad3c3abdd9b70c026cac9
https://pubmed.ncbi.nlm.nih.gov/20858953

المؤلفون: Hughes, Eleri, Clayton, Jonathan C., Kitmitto, Ashraf, Esmann, Mikael, Middleton, David A.

المصدر: Hughes , E , Clayton , J C , Kitmitto , A , Esmann , M & Middleton , D A 2007 , ' Solid-state NMR and functional measurements indicate that the conserved tyrosine residues of sarcolipin are involved directly in the inhibition of SERCA1 ' , Journal of Biological Chemistry , vol. 282 , no. 36 , pp. 26603-26613 . https://doi.org/10.1074/jbc.M611668200

مصطلحات موضوعية: chemistry: Adenosine Triphosphate, Animals, physiology: Binding Sites, chemistry: Calcium, physiology: Enzyme Activation, Hydrolysis, physiology: Ion Transport, chemistry: Lipid Bilayers, physiology: Muscle Contraction, chemistry: Muscle Proteins, Nuclear Magnetic Resonance, Biomolecular, chemistry: Peptides, chemistry: Phosphatidylcholines, physiology: Protein Binding, chemistry: Proteolipids, Rabbits, chemistry: Sarcoplasmic Reticulum, chemistry: Sarcoplasmic Reticulum Calcium-Transporting ATPases, chemistry: Tyrosine

الاتاحة: https://research.manchester.ac.uk/en/publications/9a44a9c1-0fb3-411b-a27b-e3855f308571
https://doi.org/10.1074/jbc.M611668200
http://www.jbc.org/cgi/reprint/282/36/26603

المؤلفون: De Souza, Patricia M., Kankaanranta, Hannu, Michael, Ashour, Barnes, Peter J., Giembycz, Mark A., Lindsay, Mark A.

المصدر: De Souza , P M , Kankaanranta , H , Michael , A , Barnes , P J , Giembycz , M A & Lindsay , M A 2002 , ' Caspase-catalyzed cleavage and activation of Mst1 correlates with eosinophil but not neutrophil apoptosis ' , Blood , vol. 99 , no. 9 , pp. 3432-3438 . https://doi.org/10.1182/blood.V99.9.3432

مصطلحات موضوعية: pharmacology: Antigens, CD95, drug effects: Apoptosis, metabolism: Caspases, physiology: Enzyme Activation, enzymology: Eosinophils, Humans, pharmacology: Hydrogen Peroxide, Kinetics, Molecular Weight, enzymology: Neutrophils, metabolism: Peptide Fragments, metabolism: Protein-Serine-Threonine Kinases

الاتاحة: https://research.manchester.ac.uk/en/publications/502d5fb0-921c-4e2d-b207-8c98e94723c9
https://doi.org/10.1182/blood.V99.9.3432

المؤلفون: Yang, J. Y., Widmann, C.

المصدر: Molecular and Cellular Biology, vol. 21, no. 16, pp. 5346-58

مصطلحات موضوعية: Apoptosis/*physiology Caspases/*physiology Enzyme Activation Hela Cells Humans Signal Transduction/physiology Structure-Activity Relationship Substrate Specificity ras GTPase-Activating Proteins/*physiology

Relation: info:eu-repo/semantics/altIdentifier/pmid/11463818; info:eu-repo/semantics/altIdentifier/pissn/0270-7306; https://serval.unil.ch/notice/serval:BIB_B10271B3CCE4

الاتاحة: https://serval.unil.ch/notice/serval:BIB_B10271B3CCE4
https://doi.org/10.1128/MCB.21.16.5346-5358.2001

المؤلفون: Mariotti, A., Kedeshian, P. A., Dans, M., Curatola, A. M., Gagnoux-Palacios, L., Giancotti, F. G.

المصدر: Journal of Cell Biology, vol. 155, no. 3, pp. 447-58

مصطلحات موضوعية: Animals Antigens, Surface/metabolism/*physiology Cell Movement/*physiology Enzyme Activation Epithelial Cells/physiology Hemidesmosomes/metabolism/physiology Humans Integrin alpha6beta4 Integrins/metabolism/*physiology Mice Mice, Nude Neoplasm Invasiveness Neoplasm Metastasis Neoplasms, Experimental/metabolism/pathology Phosphorylation Proto-Oncogene Proteins/genetics/*metabolism Proto-Oncogene Proteins c-fyn Rats Receptor, Epidermal Growth Factor/*metabolism *Signal Transduction Tumor Cells, Cultured src-Family Kinases/metabolism

Relation: info:eu-repo/semantics/altIdentifier/pmid/11684709; info:eu-repo/semantics/altIdentifier/pissn/0021-9525; https://serval.unil.ch/notice/serval:BIB_A9B0A36D1F24

الاتاحة: https://serval.unil.ch/notice/serval:BIB_A9B0A36D1F24
https://doi.org/10.1083/jcb.200105017

المؤلفون: Quayle, J. M., Bonev, A. D., Brayden, J. E., Nelson, M. T.

المصدر: Quayle , J M , Bonev , A D , Brayden , J E & Nelson , M T 1994 , ' Calcitonin gene-related peptide activated ATP-sensitive K+ currents in rabbit arterial smooth muscle via protein kinase A ' , Journal of Physiology , vol. 475 , no. 1 , pp. 9-13 .

مصطلحات موضوعية: pharmacology: Adenosine Triphosphate, metabolism: Adenylate Cyclase, Animals, drug effects: Biotransformation, antagonists & inhibitors: Calcitonin Gene-Related Peptide, physiology: Calcium, biosynthesis: Cyclic AMP, antagonists & inhibitors: Cyclic AMP-Dependent Protein Kinases, Electrophysiology, physiology: Enzyme Activation, pharmacology: Forskolin, pharmacology: Glyburide, drug effects: Mesenteric Arteries, drug effects: Muscle, Smooth, Vascular, drug effects: Potassium Channels, Rabbits, drug effects: Signal Transduction, drug effects: Vasodilation

الاتاحة: https://research.manchester.ac.uk/en/publications/6b13abe3-a937-45b7-86c0-71d0950e1962

المؤلفون: de Agostini, A., Patston, P. A., Marottoli, V., Carrel, S., Harpel, P. C., Schapira, M.

المصدر: Journal of Clinical Investigation, vol. 82, no. 2, pp. 700-5

مصطلحات موضوعية: Animals Antibodies, Monoclonal Complement Activating Enzymes/*metabolism Complement C1 Inactivator Proteins/*metabolism/physiology Complement C1s/*metabolism/physiology Enzyme Activation Epitopes/*isolation & purification Factor XII/*metabolism/physiology Factor XIIa Heat Humans Immunoassay Kallikreins/*blood/physiology Mice Mice, Inbred BALB C Molecular Weight Neutrophils/*enzymology Pancreatic Elastase/*metabolism/physiology Peptide Fragments/metabolism/physiology Protein Conformation Protein Denaturation Serine Endopeptidases/*metabolism/physiology

Relation: info:eu-repo/semantics/altIdentifier/pmid/2457036; info:eu-repo/semantics/altIdentifier/pissn/0021-9738; https://serval.unil.ch/notice/serval:BIB_1CC03D8800FF

الاتاحة: https://serval.unil.ch/notice/serval:BIB_1CC03D8800FF
https://doi.org/10.1172/JCI113650

المؤلفون: Pantaleo, G., Olive, D., Poggi, A., Kozumbo, W. J., Moretta, L., Moretta, A.

المصدر: European Journal of Immunology, vol. 17, no. 1, pp. 55-60

مصطلحات موضوعية: Antibodies, Monoclonal/immunology Antigens, CD27 Antigens, CD3 Antigens, Surface/*immunology Biological Transport Calcium/*metabolism Cell Line Diglycerides/*physiology Enzyme Activation Epitopes/immunology Glycerides/*physiology Humans Inositol Phosphates/*physiology Intracellular Fluid/metabolism Lymphocyte Activation Membrane Lipids/metabolism Protein Kinase C/metabolism Sugar Phosphates/*physiology T-Lymphocytes/*immunology/metabolism

Relation: info:eu-repo/semantics/altIdentifier/pmid/2434339; info:eu-repo/semantics/altIdentifier/pissn/0014-2980; https://serval.unil.ch/notice/serval:BIB_7905B124B21C

الاتاحة: https://serval.unil.ch/notice/serval:BIB_7905B124B21C
https://doi.org/10.1002/eji.1830170110

المؤلفون: Yang, J. Y., Michod, D., Walicki, J., Widmann, C.

المصدر: Biochemical Pharmacology, vol. 68, no. 6, pp. 1027-31

مصطلحات موضوعية: 1-Phosphatidylinositol 3-Kinase/metabolism Animals Apoptosis/*physiology Caspases/metabolism/*physiology Cell Survival/physiology Enzyme Activation Humans ras GTPase-Activating Proteins/metabolism/*physiology/therapeutic use ras Proteins/metabolism

Relation: info:eu-repo/semantics/altIdentifier/pmid/15313397; info:eu-repo/semantics/altIdentifier/pissn/0006-2952; https://serval.unil.ch/notice/serval:BIB_581743E009E3

الاتاحة: https://serval.unil.ch/notice/serval:BIB_581743E009E3
https://doi.org/10.1016/j.bcp.2004.03.043