المؤلفون: Silvana K. Haßel, Seyed Mohammad Taghdisi, Anna Jonczyk, H. James Stunden, Günter Mayer, Joachim L. Schultze, Marc Beyer, Laia Civit, Eicke Latz, Michael Blank, Carsten Gröber

المصدر: Civit Pitarch, L, Taghdisi, S M, Jonczyk, A, Hassel, S K, Gröber, C, Blank, M, Stunden, J, Beyer, M, Schultze, J, Latz, E & Mayer, G 2018, ' Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells ', Biochimie, vol. 145, pp. 53-62 . https://doi.org/10.1016/j.biochi.2017.10.007
Biochimie 145, 53-62 (2018). doi:10.1016/j.biochi.2017.10.007

مصطلحات موضوعية: 0301 basic medicine, Screening techniques, chemistry [Aptamers, Nucleotide], pharmacokinetics [Aptamers, Nucleotide], Aptamer, Antineoplastic Agents, Breast Neoplasms, Computational biology, pathology [Breast Neoplasms], Biology, DNA Aptamers, Cell selex, pharmacology [Aptamers, Nucleotide], Biochemistry, methods [SELEX Aptamer Technique], DNA sequencing, chemical synthesis [Antineoplastic Agents], 03 medical and health sciences, chemistry [Antineoplastic Agents], Humans, metabolism [Breast Neoplasms], pharmacology [Antineoplastic Agents], methods [Drug Screening Assays, Antitumor], Oligonucleotide, SELEX Aptamer Technique, Binding properties, chemical synthesis [Aptamers, Nucleotide], General Medicine, Aptamers, Nucleotide, 030104 developmental biology, A549 Cells, ddc:540, MCF-7 Cells, pharmacokinetics [Antineoplastic Agents], Female, drug therapy [Breast Neoplasms], Breast cancer cells, Drug Screening Assays, Antitumor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c5b5cc0c510193c317291b71c3107a
https://doi.org/10.1016/j.biochi.2017.10.007

المؤلفون: Gurwitz, David, Newman, William

المصدر: Gurwitz , D & Newman , W 2008 , ' Re: Pharmacogenomic variation of CYP2D6 and the choice of optimal adjuvant endocrine therapy for postmenopausal breast cancer: A modeling analysis ' , Journal of the National Cancer Institute , vol. 100 , no. 18 , pp. 1331 . https://doi.org/10.1093/jnci/djn269

مصطلحات موضوعية: pharmacokinetics: Antineoplastic Agents, Hormonal, pharmacokinetics: Aromatase Inhibitors, statistics & numerical data: Asian Continental Ancestry Group, drug therapy: Breast Neoplasms, Chemotherapy, Adjuvant, genetics: Cytochrome P-450 CYP2D6, Decision Making, Disease-Free Survival, pharmacokinetics: Estrogen Receptor Modulators, Female, Genotype, Humans, Markov Chains, Middle Aged, pharmacokinetics: Nitriles, Patient Participation, Postmenopause, pharmacokinetics: Tamoxifen, pharmacokinetics: Triazoles

الاتاحة: https://research.manchester.ac.uk/en/publications/450db787-3e1a-46f1-be8e-43e953ad3118
https://doi.org/10.1093/jnci/djn269

المؤلفون: Price, P.

المصدر: Price , P 2007 , ' The role of PET scanning in determining pharmacoselective doses in oncology drug development. ' , Ernst Schering Research Foundation workshop , no. 59 , pp. 185-193 .

مصطلحات موضوعية: Animals, pharmacokinetics: Antineoplastic Agents, drug therapy: Brain Neoplasms, Dose-Response Relationship, Drug, Drug Design, metabolism: Fluorodeoxyglucose F18, Humans, Models, Chemical, drug therapy: Neoplasms, Perfusion, methods: Positron-Emission Tomography, methods: Technology, Pharmaceutical, Time Factors

Relation: https://research.manchester.ac.uk/en/publications/bec58321-6cd2-46b2-a01b-7d21a2b69149

الاتاحة: https://research.manchester.ac.uk/en/publications/bec58321-6cd2-46b2-a01b-7d21a2b69149

المؤلفون: Workman, Paul, Aboagye, Eric O., Chung, Yuen Li, Griffiths, John R., Hart, Rachel, Leach, Martin O., Maxwell, Ross J., McSheehy, Paul M J, Price, Pat M., Zweit, Jamal

المصدر: Workman , P , Aboagye , E O , Chung , Y L , Griffiths , J R , Hart , R , Leach , M O , Maxwell , R J , McSheehy , P M J , Price , P M & Zweit , J 2006 , ' Minimally invasive Pharmacokinetic and Pharmacodynamic Technologies in hypothesis-testing clinical trials of innovative therapies ' , Journal of the National Cancer Institute , vol. 98 , no. 9 , pp. 580-598 . https://doi.org/10.1093/jnci/djj162

مصطلحات موضوعية: pharmacokinetics: Antineoplastic Agents, Apoptosis, metabolism: Biological Markers, Blood Flow Velocity, Cell Hypoxia, Clinical Trials as Topic, Clinical Trials, Phase I as Topic, Phase II as Topic, Humans, methods: Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy, drug therapy: Neoplasms, Positron-Emission Tomography, diagnostic use: Radiopharmaceuticals, Sensitivity and Specificity, methods: Tomography, X-Ray Computed, methods: Ultrasonography

الاتاحة: https://research.manchester.ac.uk/en/publications/eefaf025-79f7-4f75-919f-44dec143c87c
https://doi.org/10.1093/jnci/djj162

المؤلفون: West, Catharine M L, Jones, Terry, Price, Pat

المصدر: West , C M L , Jones , T & Price , P 2004 , ' The potential of positron-emission tomography to study anticancer-drug resistance ' , Nature Reviews Cancer , vol. 4 , no. 6 , pp. 457-469 .

مصطلحات موضوعية: pharmacokinetics: Antineoplastic Agents, Drug Resistance, Neoplasm, Humans, physiopathology: Neoplasms, Tomography, Emission-Computed

الاتاحة: https://research.manchester.ac.uk/en/publications/f7d7b739-1b30-4ac8-bbca-299c9c04ec7a

المؤلفون: Jayson, GC, Zweit, Jamal, Jackson, Alan, Mulatero, C, Julyan, P, Ranson, Malcolm, Broughton, L, Wagstaff, J, Hakannson, L, Groenewegen, G, Bailey, J, Smith, N, Hastings, D, Lawrance, J, Haroon, Hamied, Ward, T, McGown, AT, Tang, T, Levitt, D, Marreaud, S, Lehmann, FF, Herold, M, Zwierzina, H

المصدر: Jayson , GC , Zweit , J , Jackson , A , Mulatero , C , Julyan , P , Ranson , M , Broughton , L , Wagstaff , J , Hakannson , L , Groenewegen , G , Bailey , J , Smith , N , Hastings , D , Lawrance , J , Haroon , H , Ward , T , McGown , AT , Tang , T , Levitt , D , Marreaud , S , Lehmann , FF , Herold , M & Zwierzina , H 2002 , ' Molecular Imaging and Biological Evaluation ....

مصطلحات موضوعية: Animals, pharmacokinetics: Antibodies, Monoclonal, Antibody Formation, pharmacokinetics: Antineoplastic Agents, Capillary Permeability, Dose-Response Relationship, Immunologic, Drug Design, Drug Evaluation, Preclinical, immunology: Endothelial Growth Factors, Humans, Iodine Radioisotopes, immunology: Lymphokines, immunology: Macaca fascicularis, methods: Magnetic Resonance Imaging, Maximum Tolerated Dose, Mice, Inbred BALB C, Middle Aged, blood supply: Neoplasms, physiopathology: Neovascularization, Pathologic, Tissue Distribution, Tomography, Emission-Computed, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factors

الاتاحة: https://research.manchester.ac.uk/en/publications/ae05bd35-b98f-4bf5-8b15-a8737a848e0f
https://doi.org/10.1093/jnci/94.19.1484

المؤلفون: Ranson, Malcolm, Hammond, Lisa A., Ferry, David, Kris, Mark, Tullo, Andrew, Murray, Philip I., Miller, Vince, Averbuch, Steve, Ochs, Judy, Morris, Charles, Feyereislova, Andrea, Swaisland, Helen, Rowinsky, Eric K.

المصدر: Ranson , M , Hammond , L A , Ferry , D , Kris , M , Tullo , A , Murray , P I , Miller , V , Averbuch , S , Ochs , J , Morris , C , Feyereislova , A , Swaisland , H & Rowinsky , E K 2002 , ' ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: Results of a phase I trial ' , Journal of Clinical Oncology , vol. 20 , no. 9 , pp. 2240-2250 ....

مصطلحات موضوعية: Administration, Oral, Adult, Aged, pharmacokinetics: Antineoplastic Agents, Area Under Curve, Dose-Response Relationship, Drug, Female, Humans, Male, Middle Aged, drug therapy: Neoplasms, antagonists & inhibitors: Protein-Tyrosine Kinase, pharmacokinetics: Quinazolines, antagonists & inhibitors: Receptor, Epidermal Growth Factor, Treatment Outcome

الاتاحة: https://research.manchester.ac.uk/en/publications/f5a9674f-3780-4851-a1cb-53d10b64e0c7
https://doi.org/10.1200/JCO.2002.10.112