-
1
المؤلفون: Thomas Koeglsperger, Svenja-Lotta Rumpf, Patricia Schließer, Felix L. Struebing, Matthias Brendel, Johannes Levin, Claudia Trenkwalder, Günter U. Höglinger, Jochen Herms
المصدر: Molecular neurodegeneration 18(1), 32 (2023). doi:10.1186/s13024-023-00622-7
مصطلحات موضوعية: pathology [Lewy Bodies], pathology [Lewy Body Disease], pathology [Nerve Degeneration], Prodromal Parkinson’s disease (PD), pathology [Parkinson Disease], Cellular and Molecular Neuroscience, Lewy body α-Synuclein, Incidental Lewy body disease (iLBD), ddc:570, alpha-Synuclein, Humans, Neurology (clinical), REM-sleep behaviour disorder (RBD), Molecular Biology, Neuropathology, Enteric nervous system (ENS)
-
2
المؤلفون: Florian Wegner, Selma Staege, Andreas Hermann, Stefan Stefanov, Hannes Glass, Susanne Petri, Dieter Edbauer, Rajat Bhatnagar, Antje Janosch, Petra Freitag, Anne-Karin Kahlert, Marc Bickle, Jared Sterneckert, Tanja Richter, Arun Pal, Carina Schludi, Walter Just, Norman Kalmbach, Masin Abo-Rady
المصدر: Stem Cell Reports, Vol 14, Iss 3, Pp 390-405 (2020)
Stem Cell Reports
Stem cell reports 14(3), 390-405 (2020). doi:10.1016/j.stemcr.2020.01.010مصطلحات موضوعية: 0301 basic medicine, amyotrophic lateral sclerosis, genetics [Transcriptome], Apoptosis, metabolism [Axons], Biochemistry, genetics [Gain of Function Mutation], Pathogenesis, metabolism [HSP40 Heat-Shock Proteins], Gene Knockout Techniques, 0302 clinical medicine, C9orf72, disease modeling, Axon, Amyotrophic lateral sclerosis, drug effects [Axons], drug effects [Motor Neurons], Induced pluripotent stem cell, lcsh:QH301-705.5, HSP70, pharmacology [Pyrrolidinones], Motor Neurons, lcsh:R5-920, DNA Repeat Expansion, drug effects [Induced Pluripotent Stem Cells], gene editing, drug effects [Cell Differentiation], pathology [Nerve Degeneration], Cell Differentiation, Pyrrolidinones, Cell biology, metabolism [Induced Pluripotent Stem Cells], genetics [Amyotrophic Lateral Sclerosis], medicine.anatomical_structure, metabolism [C9orf72 Protein], Gain of Function Mutation, lcsh:Medicine (General), pathology [Motor Neurons], induced pluripotent stem cells, metabolism [HSP70 Heat-Shock Proteins], genetics [DNA Repeat Expansion], C9ORF72, axonal trafficking, drug effects [Apoptosis], Biology, Cytoplasmic Granules, Models, Biological, Article, 03 medical and health sciences, Heat shock protein, Genetics, medicine, Humans, pharmacology [Benzhydryl Compounds], HSP70 Heat-Shock Proteins, ddc:610, Benzhydryl Compounds, pathology [Amyotrophic Lateral Sclerosis], genetics [C9orf72 Protein], C9orf72 Protein, metabolism [Motor Neurons], Cell Biology, HSP40 Heat-Shock Proteins, medicine.disease, metabolism [Cytoplasmic Granules], Axons, Hsp70, 030104 developmental biology, drug effects [Cytoplasmic Granules], HSP40, lcsh:Biology (General), heat shock proteins, Nerve Degeneration, Transcriptome, Trinucleotide repeat expansion, 030217 neurology & neurosurgery, Developmental Biology
-
3
المؤلفون: Jiaxing Wang, Eldon E. Geisert, Felix L Struebing
المصدر: Experimental eye research 207, 108571-(2021). doi:10.1016/j.exer.2021.108571
مصطلحات موضوعية: 0301 basic medicine, Retinal Ganglion Cells, Optic nerve crush, genetic structures, Microarray, Glaucoma, genetics [Transcriptome], Transcriptome, chemistry.chemical_compound, genetics [Glaucoma], genetics [Optic Nerve Injuries], Mice, 0302 clinical medicine, Gene Regulatory Networks, GeneNetwork, Retinal ganglion cell (RGC), Neurodegeneration, pathology [Nerve Degeneration], RNA sequencing, Sensory Systems, Up-Regulation, Optic nerve, Signal Transduction, pathology [Glaucoma], Biology, pathology [Retinal Ganglion Cells], Retinal ganglion, 03 medical and health sciences, Cellular and Molecular Neuroscience, physiology [Signal Transduction], medicine, Animals, ddc:610, Eye Proteins, Sequence Analysis, RNA, Gene Expression Profiling, Retinal, pathology [Optic Nerve Injuries], medicine.disease, eye diseases, Gene expression profiling, Ophthalmology, Disease Models, Animal, 030104 developmental biology, chemistry, genetics [Eye Proteins], Optic Nerve Injuries, Nerve Degeneration, 030221 ophthalmology & optometry, sense organs, Neuroscience
-
4
المؤلفون: Andreas Kupsch, Jens K. Haumesser, Christoph van Riesen, Daniel Harnack, Johanna Kühn, Vadim V. Nikulin, Andrea A. Kühn, Franziska Pellegrini, Maximilian H. Beck, Wolf-Julian Neumann, Jennifer Altschüler
المصدر: Experimental neurology 335, 113513-(2021). doi:10.1016/j.expneurol.2020.113513
مصطلحات موضوعية: 0301 basic medicine, Male, Parkinson's disease, pathology [Dopaminergic Neurons], Deep Brain Stimulation, physiopathology [Neostriatum], Striatum, pathology [Parkinsonian Disorders], 0302 clinical medicine, Basal ganglia, Beta oscillations, Movement Disorders, pathology [Motor Cortex], Neurodegeneration, Motor Cortex, pathology [Nerve Degeneration], Electroencephalography, Subthalamic nucleus, medicine.anatomical_structure, Treatment Outcome, Neurology, Primary motor cortex, Motor cortex, chemically induced [Parkinsonian Disorders], 03 medical and health sciences, Hydroxydopamines, Developmental Neuroscience, Parkinsonian Disorders, Subthalamic Nucleus, medicine, Animals, ddc:610, Pars compacta, business.industry, Dopaminergic Neurons, physiopathology [Subthalamic Nucleus], pathology [Movement Disorders], medicine.disease, Electrophysiological Phenomena, Rats, Neostriatum, 030104 developmental biology, Nerve Degeneration, business, Beta Rhythm, Neuroscience, 030217 neurology & neurosurgery
-
5
المؤلفون: Philipp E. Geyer, Nikolaus Deigendesch, Johannes Müller, Maximilian T. Strauss, Majken K. Jensen, Frank Leypoldt, Oliver Peters, Carola G. Schipke, Enise I. Incesoy, Mikael Simons, Peter Koertvelyessy, Henrik Zetterberg, Manja Koch, Daniel Bittner, Matthias Mann, Jakob M. Bader
المصدر: Molecular Systems Biology
Molecular systems biology 16(6), e9356 (2020). doi:10.15252/msb.20199356
Molecular Systems Biology, Vol 16, Iss 6, Pp n/a-n/a (2020)
Bader, J M, Geyer, P E, Müller, J B, Strauss, M T, Koch, M, Leypoldt, F, Koertvelyessy, P, Bittner, D, Schipke, C G, Incesoy, E I, Peters, O, Deigendesch, N, Simons, M, Jensen, M K, Zetterberg, H & Mann, M 2020, ' Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease ', Molecular Systems Biology, vol. 16, no. 6, e9356 . https://doi.org/10.15252/msb.20199356
MOLECULAR SYSTEMS BIOLOGYمصطلحات موضوعية: Proteomics, Medicine (General), Proteome, Disease, Bioinformatics, Cohort Studies, Machine Learning, 0302 clinical medicine, Cerebrospinal fluid, Biology (General), CSF albumin, mass spectrometry, Neurons, 0303 health sciences, Applied Mathematics, Neurodegeneration, neurodegeneration, pathology [Nerve Degeneration], Articles, Alzheimer's disease, 3. Good health, cerebrospinal fluid [Alzheimer Disease], cerebrospinal fluid [Biomarkers], Computational Theory and Mathematics, metabolism [Neurons], General Agricultural and Biological Sciences, Function and Dysfunction of the Nervous System, Glycolysis, Information Systems, QH301-705.5, tau Proteins, Biology, General Biochemistry, Genetics and Molecular Biology, Article, cerebrospinal fluid, 03 medical and health sciences, R5-920, Alzheimer Disease, ddc:570, medicine, Dementia, Humans, 030304 developmental biology, Biomarkers & Diagnostic Imaging, General Immunology and Microbiology, PARK7, Reproducibility of Results, metabolism [Proteome], medicine.disease, cerebrospinal fluid [tau Proteins], Nerve Degeneration, 030217 neurology & neurosurgery, Biomarkers, Neuroscience
وصف الملف: application/pdf
-
6
المصدر: Neurobiology of disease 117, 189-202 (2018). doi:10.1016/j.nbd.2018.06.005
Neurobiology of Disease, Vol 117, Iss, Pp 189-202 (2018)مصطلحات موضوعية: pathology [Tauopathies], 0301 basic medicine, Nervous system, Tau pathology, Tau protein, biosynthesis [Caenorhabditis elegans Proteins], Excitotoxicity, Glutamic Acid, tau Proteins, biosynthesis [tau Proteins], Frontotemporal dementia (FTD), medicine.disease_cause, Cathepsin, lcsh:RC321-571, Animals, Genetically Modified, 03 medical and health sciences, Glutamatergic, ddc:570, medicine, Animals, Alzheimer disease (AD), Caenorhabditis elegans, Caenorhabditis elegans Proteins, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, metabolism [Nerve Degeneration], biology, genetics [Caenorhabditis elegans Proteins], metabolism [Glutamic Acid], Neurodegeneration, genetics [Tauopathies], pathology [Nerve Degeneration], genetics [Glutamic Acid], medicine.disease, biology.organism_classification, Caspase, genetics [tau Proteins], 030104 developmental biology, medicine.anatomical_structure, Neurology, genetics [Nerve Degeneration], biology.protein, physiology [Calcium Signaling], Tauopathy, metabolism [Tauopathies], Alzheimer's disease, Calreticulin, Neuroscience
-
7
المؤلفون: Franzmeier, Nicolai, Suárez-Calvet, M., Kleinberger, Gernot, Doraiswamy, P Murali, Petrella, Jeffrey R, Arnold, Steven E, Karlawish, Jason H, Wolk, David, Smith, Charles D, Jicha, Greg, Hardy, Peter, Lopez, Oscar L, Oakley, Mary Ann, Haass, Christian, Simpson, Donna M, Ismail, M Saleem, Brand, Connie, Mulnard, Ruth A, Thai, Gaby, Mc-Adams-Ortiz, Catherine, Diaz-Arrastia, Ramon, Martin-Cook, Kristen, DeVous, Michael, Levey, Allan I, Ewers, Michael, Lah, James J, Cellar, Janet S, Burns, Jeffrey M, Anderson, Heather S, Swerdlow, Russell H, Bartzokis, George, Silverman, Daniel H S, Lu, Po H, Apostolova, Liana, Graff-Radford, Neill R, Initiative, Alzheimer’s Disease Neuroimaging, Parfitt, Francine, Johnson, Heather, Farlow, Martin, Herring, Scott, Hake, Ann M, van Dyck, Christopher H, Carson, Richard E, MacAvoy, Martha G, Chertkow, Howard, Bergman, Howard, Weiner, Michael, Hosein, Chris, Black, Sandra, Stefanovic, Bojana, Caldwell, Curtis, Hsiung, Ging-Yuek Robin, Feldman, Howard, Assaly, Michele, Kertesz, Andrew, Rogers, John, Trost, Dick, Aisen, Paul, Bernick, Charles, Munic, Donna, Wu, Chuang-Kuo, Johnson, Nancy, Mesulam, Marsel, Sadowsky, Carl, Martinez, Walter, Villena, Teresa, Turner, Raymond Scott, Johnson, Kathleen, Novak, Gerald, Reynolds, Brigid, Sperling, Reisa A, Frey, Meghan, Johnson, Keith A, Rosen, Allyson, Tinklenberg, Jared, Ashford, Wes, Sabbagh, Marwan, Belden, Christine, Jacobson, Sandra, Green, Robert C, Killiany, Ronald, Norbash, Alexander, Nair, Anil, Obisesan, Thomas O, Wolday, Saba, Bwayo, Salome K, Lerner, Alan, Hudson, Leon, Ogrocki, Paula, Fletcher, Evan, Montine, Tom, Carmichael, Owen, Kittur, Smita, Borrie, Michael, Lee, T-Y, Bartha, Rob, Johnson, Sterling, Asthana, Sanjay, Carlsson, Cynthia M, Potkin, Steven G, Preda, Adrian, Petersen, Ronald, Nguyen, Dana, Tariot, Pierre, Fleisher, Adam, Reeder, Stephanie, Bates, Vernice, Capote, Horacio, Rainka, Michelle, Hendin, Barry A, Scharre, Douglas W, Kataki, Maria, Frontzkowski, Lukas, Gamst, Anthony, Zimmerman, Earl A, Celmins, Dzintra, Brown, Alice D, Hosp, Hartford, Pearlson, Godfrey D, Blank, Karen, Anderson, Karen, Santulli, Robert B, Schwartz, Eben S, Williamson, Jeff D, Thomas, Ronald G, Sink, Kaycee M, Watkins, Franklin, Ott, Brian R, Querfurth, Henry, Tremont, Geoffrey, Salloway, Stephen, Malloy, Paul, Correia, Stephen, Rosen, Howard J, Miller, Bruce L, Donohue, Michael, Mintzer, Jacobo, Longmire, Crystal Flynn, Spicer, Kenneth, Walter, Sarah, Gessert, Devon, Sather, Tamie, Beckett, Laurel, Harvey, Danielle, Kornak, John, Jack, Clifford R, Moore, Annah, Dale, Anders, Bernstein, Matthew, Felmlee, Joel, Fox, Nick, Thompson, Paul, Schuff, Norbert, Alexander, Gene, DeCarli, Charles, Jagust, William, Bandy, Dan, Hohman, Timothy J, Koeppe, Robert A, Foster, Norm, Reiman, Eric M, Chen, Kewei, Mathis, Chet, Morris, John, Cairns, Nigel J, Taylor-Reinwald, Lisa, Trojanowki, J. Q., Shaw, Les, Morenas-Rodriguez, Estrella, Lee, Virginia M Y, Korecka, Magdalena, Toga, Arthur W, Crawford, Karen, Neu, Scott, Saykin, Andrew J, Foroud, Tatiana M, Potkin, Steven, Shen, Li, Kachaturian, Zaven, Nuscher, Brigitte, Frank, Richard, Snyder, Peter J, Molchan, Susan, Kaye, Jeffrey, Dolen, Sara, Quinn, Joseph, Schneider, Lon S, Pawluczyk, Sonia, Spann, Bryan M, Brewer, James, Shaw, Leslie, Vanderswag, Helen, Heidebrink, Judith L, Lord, Joanne L, Johnson, Kris, Doody, Rachelle S, Villanueva-Meyer, Javier, Chowdhury, Munir, Stern, Yaakov, Honig, Lawrence S, Bell, Karen L, Trojanowski, John Q, Morris, John C, Mintun, Mark A, Schneider, Stacy, Marson, Daniel, Griffith, Randall, Clark, David, Grossman, Hillel, Mitsis, Effie, Romirowsky, Aliza, deToledo-Morrell, Leyla, Dichgans, Martin, Shah, Raj C, Duara, Ranjan, Varon, Daniel, Roberts, Peggy, Albert, Marilyn, Onyike, Chiadi, Kielb, Stephanie, Rusinek, Henry, de Leon, Mony J, Glodzik, Lidia
المصدر: Molecular neurodegeneration 15(1), 57 (2020). doi:10.1186/s13024-020-00407-2
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-10 (2020)
Molecular Neurodegeneration
Molecular neurodegeneration, vol 15, iss 1مصطلحات موضوعية: Male, Aging, pathology [Cognitive Dysfunction], Apolipoprotein E4, Cognitive decline, genetics [Alzheimer Disease], Neurodegenerative, lcsh:Geriatrics, Alzheimer's Disease, lcsh:RC346-429, pathology [Alzheimer Disease], Immunologic, Receptors, 80 and over, 2.1 Biological and endogenous factors, sTREM2, Microglial activation, Aetiology, Receptors, Immunologic, genetics [Apolipoprotein E4], Aged, 80 and over, Membrane Glycoproteins, pathology [Nerve Degeneration], cerebrospinal fluid [Alzheimer Disease], cerebrospinal fluid [Cognitive Dysfunction], Neurological, Female, cerebrospinal fluid [Membrane Glycoproteins], Alzheimer’s disease, Research Article, Clinical Sciences, ApoE4, Clinical Research, Alzheimer Disease, ddc:570, Acquired Cognitive Impairment, Genetics, Humans, Cognitive Dysfunction, Genetic Predisposition to Disease, Neurodegeneration, lcsh:Neurology. Diseases of the nervous system, Aged, Neurology & Neurosurgery, Neurosciences, genetics [Cognitive Dysfunction], Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Alzheimer’s Disease Neuroimaging Initiative, Brain Disorders, lcsh:RC952-954.6, Nerve Degeneration, Dementia
وصف الملف: application/pdf
-
8
المؤلفون: Martin Hrabé de Angelis, Thomas Misgeld, Katherine D. LaClair, Monika S. Brill, Manuela Neumann, Qihui Zhou, Meike Michaelsen, Aleksandar Janjic, Wolfgang Enard, Wolfgang Wurst, Daniel Farny, Benedikt Wefers, Birgit Rathkolb, Mikolaj Cygan, Dieter Edbauer, Thomas Arzberger
المصدر: Acta Neuropathol. 140, 121–142 (2020)
Acta neuropathologica 140(2), 121-142 (2020). doi:10.1007/s00401-020-02176-0
Acta Neuropathologicaمصطلحات موضوعية: immunology [Amyotrophic Lateral Sclerosis], Mice, 0302 clinical medicine, C9orf72, pathology [Neurons], Amyotrophic lateral sclerosis, Neurons, 0303 health sciences, DNA Repeat Expansion, Neurodegeneration, pathology [Nerve Degeneration], FTD, ddc, genetics [Amyotrophic Lateral Sclerosis], medicine.anatomical_structure, genetics [Nerve Degeneration], Interferon, Microglia, medicine.symptom, medicine.medical_specialty, Ataxia, Transgene, immunology [Nerve Degeneration], genetics [DNA Repeat Expansion], Congenic, Mice, Transgenic, Biology, Mouse model, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, Internal medicine, medicine, Animals, ddc:610, pathology [Amyotrophic Lateral Sclerosis], biosynthesis [Interferons], genetics [C9orf72 Protein], Neuroinflammation, 030304 developmental biology, Original Paper, C9orf72 Protein, Amyotrophic Lateral Sclerosis, Skeletal muscle, medicine.disease, Disease Models, Animal, Endocrinology, Nerve Degeneration, Als, Ftd, Mouse Model, Interferons, Neurology (clinical), ALS, 030217 neurology & neurosurgery
وصف الملف: application/pdf
-
9
المؤلفون: Mehmet Ilyas Cosacak, Susanne Reinhardt, Violeta Mashkaryan, Yixin Zhang, Alvin Kuriakose Thomas, Cynthia Froc, Caghan Kizil, Thomas Kurth, Christos Papadimitriou, Andreas Dahl, Prabesh Bhattarai
المساهمون: German Research Center for Neurodegenerative Diseases - Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Institute of Anatomy and Center for Regenerative Therapies, TU Dresden (CRTD), B CUBE, Center for Molecular Bioengineering, Institut des Neurosciences Paris-Saclay (NeuroPSI), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Cell Reports, Vol 17, Iss 4, Pp 941-948 (2016)
Cell reports 17(4), 941-948 (2016). doi:10.1016/j.celrep.2016.09.075
Cell Reports
Cell Reports, Elsevier Inc, 2016, 17 (4), pp.941-948. ⟨10.1016/j.celrep.2016.09.075⟩مصطلحات موضوعية: 0301 basic medicine, Aging, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, Cell Plasticity, neural stem cell, pathology [Aging], Neural Stem Cells, pathology [Brain], metabolism [Peptide Fragments], metabolism [Zebrafish], cytology [Neural Stem Cells], Zebrafish, lcsh:QH301-705.5, STAT6, Neurons, Microglia, [SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior, Neurodegeneration, Neurogenesis, neurodegeneration, [SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences, pathology [Nerve Degeneration], Brain, amyloid beta-protein (1-42), Neural stem cell, Cell biology, medicine.anatomical_structure, Phenotype, medicine.symptom, Alzheimer’s disease, Signal Transduction, metabolism [Interleukin-4], metabolism [Amyloid beta-Peptides], Inflammation, metabolism [STAT6 Transcription Factor], Biology, Amyloid-β42, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Protein Aggregates, medicine, Animals, ddc:610, Progenitor cell, Interleukin 4, Cell Proliferation, Amyloid beta-Peptides, interlukin-4, medicine.disease, biology.organism_classification, Peptide Fragments, 030104 developmental biology, lcsh:Biology (General), metabolism [Brain], inflammation, regeneration, neuro-immune crosstalk, Immunology, Nerve Degeneration, Interleukin-4, STAT6 Transcription Factor
-
10
المؤلفون: Ya Fei Xu, Jeannie Chew, Jonathan C. Grima, Kevin B. Boylan, Amanda M. Liesinger, Wen Lang Lin, Chad A. Dickey, Guojun Bu, Christopher D. Link, Jennifer Gass, Yong Jie Zhang, Zizhao S. Wang, Aliesha Garrett, Emilie A. Perkerson, Jeremy D. Baker, Hiroki Sasaguri, Jeannette N. Stankowski, Mei Yue, Clotilde Lagier-Tourenne, Rebecca B. Katzman, Leonard Petrucelli, Jie Jiang, John D. Fryer, Tania F. Gendron, Karen Jansen-West, Monica Castanedes-Casey, Lillian M. Daughrity, Jimei Tong, Aishe Kurti, Dieter Edbauer, Dennis W. Dickson, Mitsuru Shinohara, Melissa E. Murray, Jeffrey D. Rothstein, Don W. Cleveland, Rosa Rademakers
المصدر: Nature reviews / Neuroscience 19(5), 668-677 (2016). doi:10.1038/nn.4272
Nature neuroscience, vol 19, iss 5
Nature neuroscienceمصطلحات موضوعية: 0301 basic medicine, metabolism [Inclusion Bodies], Gene Expression, Neurodegenerative, Inclusion bodies, Mice, genetics [Gene Expression], 0302 clinical medicine, pathology [Brain], C9orf72, Gene expression, Psychology, pathology [Neurons], Guanine Nucleotide Exchange Factors, ultrastructure [Inclusion Bodies], Neurons, Inclusion Bodies, C9orf72 protein, mouse, pathology [Atrophy], Behavior, Animal, General Neuroscience, Nucleocytoplasmic Transport Proteins, Neurodegeneration, Brain, pathology [Nerve Degeneration], metabolism [Proteins], Ubiquitinated Proteins, DNA-Binding Proteins, poly(glycyl-alanyl), Xpc protein, mouse, metabolism [Neurons], Frontotemporal Dementia, metabolism [Frontotemporal Dementia], Cognitive Sciences, Rad23a protein, mouse, metabolism [DNA-Binding Proteins], metabolism [Ubiquitinated Proteins], metabolism [Guanine Nucleotide Exchange Factors], Primary Cell Culture, Biology, Rad23b protein, mouse, DNA-binding protein, Article, 03 medical and health sciences, TDP-43 protein, mouse, ddc:570, Acquired Cognitive Impairment, medicine, Animals, Humans, pathology [Amyotrophic Lateral Sclerosis], Behavior, Neurology & Neurosurgery, C9orf72 Protein, toxicity [Proteins], Animal, metabolism [Amyotrophic Lateral Sclerosis], Amyotrophic Lateral Sclerosis, Neurosciences, Proteins, medicine.disease, genetics [Proteins], Brain Disorders, 030104 developmental biology, metabolism [Brain], Nucleocytoplasmic Transport, Nerve Degeneration, pathology [Frontotemporal Dementia], Mutation, ultrastructure [Brain], Dementia, Human medicine, Atrophy, Carrier Proteins, Neuroscience, 030217 neurology & neurosurgery, metabolism [Carrier Proteins]
وصف الملف: application/pdf
-
11
المؤلفون: Estrella Morenas-Rodríguez, Kai Schlepckow, Erden Eren, Anja Capell, Nicolai Franzmeier, John Q. Trojanowski, Marc Suárez-Calvet, Michael W. Weiner, Laura Piccio, Celeste M. Karch, Christian Haass, Gernot Kleinberger, Miguel Ángel Araque Caballero, Michael Ewers, Yuetiva Deming, Katrin Fellerer, Leslie M. Shaw, Johannes Levin, Carlos Cruchaga, Brigitte Nuscher
المساهمون: German Research Foundation, Munich Cluster for Systems Neurology, Association for Frontotemporal Degeneration (US), European Commission, National Institutes of Health (US), Fondazione Italiana Sclerosi Multipla, Sociedad Española de Neurología, Instituto de Salud Carlos III
المصدر: Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecular Neurodegeneration
Molecular neurodegeneration 14(1), 1 (2019). doi:10.1186/s13024-018-0301-5
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-14 (2019)
Molecular neurodegeneration, vol 14, iss 1مصطلحات موضوعية: Male, 0301 basic medicine, Aging, Pathology, Neurology, genetics [Alzheimer Disease], cerebrospinal fluid [Amyloid beta-Peptides], Neurodegenerative, lcsh:Geriatrics, lcsh:RC346-429, pathology [Alzheimer Disease], 0302 clinical medicine, Cerebrospinal fluid, genetics [Membrane Glycoproteins], Neuroinflammation, Immunologic, Receptors, 80 and over, TREM2, 2.1 Biological and endogenous factors, genetics [Receptors, Immunologic], Aetiology, Receptors, Immunologic, Aged, 80 and over, Membrane Glycoproteins, Neurodegeneration, pathology [Nerve Degeneration], Middle Aged, Alzheimer's disease, cerebrospinal fluid [Alzheimer Disease], cerebrospinal fluid [Biomarkers], Neurological, Biomarker (medicine), Female, Microglia, cerebrospinal fluid [Membrane Glycoproteins], Alzheimer’s disease, Research Article, medicine.medical_specialty, Amyloid, Clinical Dementia Rating, Clinical Sciences, tau Proteins, 03 medical and health sciences, Cellular and Molecular Neuroscience, Alzheimer Disease, ddc:570, Genetics, Acquired Cognitive Impairment, medicine, Humans, Molecular Biology, lcsh:Neurology. Diseases of the nervous system, Aged, Shedding, Neurology & Neurosurgery, Amyloid beta-Peptides, TREM2 protein, human, business.industry, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Alzheimer’s Disease Neuroimaging Initiative, medicine.disease, Brain Disorders, lcsh:RC952-954.6, Cross-Sectional Studies, 030104 developmental biology, cerebrospinal fluid [tau Proteins], Nerve Degeneration, Dementia, Neurology (clinical), business, Biomarkers, 030217 neurology & neurosurgery
وصف الملف: application/pdf
-
12
المؤلفون: Paul C. Keane, Christopher Morris, P.J. Kahle, Peter S. Hanson, Fiona E. N. LeBeau, Ahmad Khundakar, Peter G. Blain, Sarah J. Judge, Philippa D. Hepplewhite, Lina Patterson
المصدر: Neuroscience letters 711, 134437 (2019). doi:10.1016/j.neulet.2019.134437
Neuroscience Lettersمصطلحات موضوعية: 0301 basic medicine, Male, Parkinson's disease, pathology [Dopaminergic Neurons], drug effects [Dopaminergic Neurons], toxicity [Trichloroethylene], TaClo, pathology [Parkinsonian Disorders], toxicity [Neurotoxins], CE, coefficient of error, Mice, 0302 clinical medicine, TaClo, 1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline, Neurotoxin, ANOVA, analysis of variance, α-Synuclein, Chemistry, General Neuroscience, Neurodegeneration, Dopaminergic, DA, dopaminergic, pathology [Nerve Degeneration], SNpc, substantia nigra pars compacta, Substantia Nigra, alpha-Synuclein, metabolism [Neurotoxins], genetics [alpha-Synuclein], MPTP, 1-methy,4-phenyl, 1,2,3,6 tetrahyrdopyridine, Female, Genetically modified mouse, medicine.medical_specialty, DMSO, dimethylsulfoxide, TH, tyrosine hydroxylase, Neurotoxins, Substantia nigra, Mice, Transgenic, Article, 03 medical and health sciences, Parkinsonian Disorders, Internal medicine, medicine, TCE, trichloroethylene, Animals, Humans, metabolism [Trichloroethylene], ddc:610, pathology [Substantia Nigra], PD, Parkinson’s disease, Pars compacta, Dopaminergic Neurons, Wild type, medicine.disease, nervous system diseases, Trichloroethylene, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, nervous system, Nerve Degeneration, Mutation, Parkinson’s disease, drug effects [Substantia Nigra], 030217 neurology & neurosurgery
-
13
المؤلفون: Marie-Ève Tremblay, Colin K. Combs, Ann-Christin Wendeln, Nyasha J. Makoni, Mona Sohrabi, Jonas J. Neher, Marie-Kim St-Pierre, Lisa K. Gouwens, Evan C. Garrad, Michael R. Nichols
المصدر: J Neurochem
Journal of neurochemistry 149(5), 562-581 (2019). doi:10.1111/jnc.14674مصطلحات موضوعية: 0301 basic medicine, Amyloid beta, immunology [Nerve Degeneration], Inflammation, Disease, metabolism [Microglia], Biochemistry, Article, pathology [Alzheimer Disease], 03 medical and health sciences, Cellular and Molecular Neuroscience, immunology [Inflammation], 0302 clinical medicine, Alzheimer Disease, medicine, Animals, Humans, ddc:610, Neuroinflammation, Microglia, biology, business.industry, Neurodegeneration, pathology [Nerve Degeneration], medicine.disease, immunology [Microglia], immunology [Alzheimer Disease], 030104 developmental biology, medicine.anatomical_structure, nervous system, Nerve Degeneration, biology.protein, medicine.symptom, business, Neuroscience, 030217 neurology & neurosurgery
-
14
المؤلفون: Eleonora Ambrad Giovannetti, Martin Fuhrmann
المصدر: Brain research 1707, 216-226 (2019). doi:10.1016/j.brainres.2018.11.042
مصطلحات موضوعية: 0301 basic medicine, metabolism [GABAergic Neurons], metabolism [Amyloid beta-Peptides], Context (language use), tau Proteins, physiopathology [Alzheimer Disease], Synapse, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Memory, Biological neural network, physiopathology [Nerve Net], Medicine, Memory impairment, Animals, Humans, pathology [Memory Disorders], ddc:610, metabolism [gamma-Aminobutyric Acid], GABAergic Neurons, Molecular Biology, physiology [Memory], Neuroinflammation, gamma-Aminobutyric Acid, Neurons, Memory Disorders, Amyloid beta-Peptides, Microglia, business.industry, General Neuroscience, pathology [Nerve Degeneration], Brain, metabolism [tau Proteins], Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, nervous system, metabolism [Brain], metabolism [Neurons], Nerve Degeneration, Cholinergic, GABAergic, Neurology (clinical), Nerve Net, business, Neuroscience, 030217 neurology & neurosurgery, Developmental Biology
-
15
المؤلفون: Seif, M., Ziegler, G., Freund, P.
المصدر: Journal of Neurotrauma
Journal of neurotrauma 35(24), 2941-2946 (2018). doi:10.1089/neu.2017.5522مصطلحات موضوعية: Adult, Male, CSF volume, etiology [Brain Diseases], brain volume, Cerebral Ventricles, complications [Spinal Cord Injuries], Young Adult, pathology [Brain], ventricle enlargement, Humans, ddc:610, Longitudinal Studies, etiology [Nerve Degeneration], VBM, Spinal Cord Injuries, Aged, Cerebrospinal Fluid, pathology [Cerebral Ventricles], Brain Diseases, pathology [Brain Diseases], pathology [Nerve Degeneration], Brain, Original Articles, Middle Aged, cerebrospinal fluid [Brain Diseases], Magnetic Resonance Imaging, spinal cord injury, Cross-Sectional Studies, Nerve Degeneration, Female, pathology [Spinal Cord Injuries], Atrophy
وصف الملف: application/pdf
-
16
المؤلفون: Francesco Morena, Silvia De Cicco, Vasco Meneghini, Andrea Menegon, Angela Gritti, Sabata Martino, Mirella Filocamo, Serena Grossi, Maria Blomqvist, Marcus Ståhlman, Marco Luciani, Giacomo Frati
المصدر: Cell Death and Disease, Vol 9, Iss 6, Pp 1-15 (2018)
Cell death & disease 9(6), 698 (2018). doi:10.1038/s41419-018-0737-0
Cell Death & Diseaseمصطلحات موضوعية: 0301 basic medicine, Cancer Research, Arylsulfatase A, Cellular differentiation, Apoptosis, metabolism [Neural Stem Cells], pathology [Neural Stem Cells], metabolism [Lysosomes], 0302 clinical medicine, Neural Stem Cells, pathology [Neurons], metabolism [Reactive Oxygen Species], Neural cell, Neurons, pathology [Leukodystrophy, Metachromatic], lcsh:Cytology, pathology [Nerve Degeneration], Cell Differentiation, gene therapy, Neural stem cell, Cell biology, Stem cell reprogramming, metabolism [Induced Pluripotent Stem Cells], Neuroepithelial cell, metabolism [Neurons], Neuroglia, Induced Pluripotent Stem Cells, Immunology, lysosomal enzymes, iPSCs, Lysosomal storage disease, Biology, Models, Biological, Article, Glycosphingolipids, 03 medical and health sciences, Cellular and Molecular Neuroscience, ddc:570, medicine, Humans, metabolic pathways, biosynthesis [Glycosphingolipids], Progenitor cell, lcsh:QH573-671, metabolism [Neuroglia], Sulfoglycosphingolipids, pathology [Neuroglia], Leukodystrophy, metabolism [Sulfoglycosphingolipids], Leukodystrophy, Metachromatic, Cell Biology, medicine.disease, Metachromatic leukodystrophy, Oxidative Stress, 030104 developmental biology, Nerve Degeneration, Lysosomes, Reactive Oxygen Species, 030217 neurology & neurosurgery
-
17
المؤلفون: Bhattarai, Prabesh, Thomas, Alvin Kuriakose, Cosacak, Mehmet Ilyas, Papadimitriou, Christos, Mashkaryan, Violeta, Zhang, Yixin, Kizil, Caghan
المصدر: JoVE journal Neuroscience(128), 56014 (2017). doi:10.3791/56014
مصطلحات موضوعية: animal structures, Neurogenesis, drug effects [Neurogenesis], chemical synthesis [Amyloid beta-Peptides], pathology [Alzheimer Disease], pathology [Brain], Alzheimer Disease, ddc:570, chemically induced [Alzheimer Disease], Animals, Zebrafish, Amyloid beta-Peptides, fungi, chemically induced [Nerve Degeneration], pathology [Nerve Degeneration], Brain, toxicity [Peptide Fragments], amyloid beta-protein (1-42), Peptide Fragments, toxicity [Amyloid beta-Peptides], Disease Models, Animal, Nerve Degeneration, drug effects [Brain], chemical synthesis [Peptide Fragments], Neuroscience
-
18
المؤلفون: Christina Ising, Michael T. Heneka
المصدر: Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 2, Pp 1-8 (2018)
Cell death & disease 9(2), 120 (2018). doi:10.1038/s41419-017-0153-xمصطلحات موضوعية: 0301 basic medicine, Cancer Research, immunology [Nerve Degeneration], Immunology, Disease, Review Article, Biology, Pathogenesis, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Immunity, ddc:570, medicine, Bystander effect, pathology [Neurons], Compartment (development), Animals, Humans, lcsh:QH573-671, immunology [Neurodegenerative Diseases], Neurons, Innate immune system, Microglia, lcsh:Cytology, metabolism [Inflammation Mediators], Neurodegeneration, pathology [Neurodegenerative Diseases], pathology [Nerve Degeneration], Neurodegenerative Diseases, Cell Biology, medicine.disease, Immunity, Innate, 030104 developmental biology, medicine.anatomical_structure, nervous system, Nerve Degeneration, Inflammation Mediators, immunology [Neurons], Neuroscience, 030217 neurology & neurosurgery
-
19
المؤلفون: Martin Fuhrmann, Giulio Calza, Enzo Scifo, Rabah Soliymani, Maciej Lalowski, Marc Baumann
المساهمون: Medicum, Department of Biochemistry and Developmental Biology
المصدر: Expert review of proteomics 14(6), 545-559 (2017). doi:10.1080/14789450.2017.1335200
Expert Review of Proteomicsمصطلحات موضوعية: 0301 basic medicine, Proteomics, Proteome, Systems biology, Computational biology, Mass spectrometry, Bioinformatics, Biochemistry, Mass spectrometry imaging, genetics [Protein Processing, Post-Translational], 03 medical and health sciences, pathology [Brain], Tandem Mass Spectrometry, Animals, Humans, ddc:610, Molecular Biology, Cell specific, 318 Medical biotechnology, Chemistry, Systems Biology, Brain, pathology [Nerve Degeneration], Alternative treatment, Review article, 030104 developmental biology, genetics [Proteome], MASS SPECTROMETRY METHOD, metabolism [Brain], genetics [Nerve Degeneration], Nerve Degeneration, 1182 Biochemistry, cell and molecular biology, PROTEOMICS, Protein Processing, Post-Translational, methods [Systems Biology]
-
20
المؤلفون: Eleonora Aronica, Daniela Rossi, Liliana Brambilla, Chiara F. Valori, Francesca Martorana, Giulia Guidotti, Anand Iyer
المساهمون: Brambilla, L, Guidotti, G, Martorana, F, Iyer, A, Aronica, E, Valori, C, Rossi, D, AII - Amsterdam institute for Infection and Immunity, Pathology, ANS - Cellular & Molecular Mechanisms, APH - Amsterdam Public Health
المصدر: Human molecular genetics 25(14), ddw161 (2016). doi:10.1093/hmg/ddw161
Human molecular genetics, 25(14), 3080-3095. Oxford University Press
Europe PubMed Centralمصطلحات موضوعية: 0301 basic medicine, Nervous system, animal diseases, Mice, 0302 clinical medicine, Superoxide Dismutase-1, Sod1 protein, mouse, Neurotrophic factors, genetics [Glial Cell Line-Derived Neurotrophic Factor], Glial cell line-derived neurotrophic factor, Amyotrophic lateral sclerosis, Genetics (clinical), pathology [Astrocytes], Motor Neurons, metabolism [Astrocytes], Neurodegeneration, pathology [Nerve Degeneration], General Medicine, Anatomy, genetics [Superoxide Dismutase-1], genetics [Amyotrophic Lateral Sclerosis], medicine.anatomical_structure, Spinal Cord, Receptors, Tumor Necrosis Factor, Type I, genetics [Nerve Degeneration], Disease Progression, Signal Transduction, metabolism [Spinal Cord], pathology [Motor Neurons], Central nervous system, Mice, Transgenic, pathology [Spinal Cord], Biology, biosynthesis [Tumor Necrosis Factor-alpha], Transneuronal degeneration, astrocytes, TNFR1, GDNF, ALS, motor neuron degeneration, 03 medical and health sciences, ddc:570, Genetics, medicine, Animals, Humans, Glial Cell Line-Derived Neurotrophic Factor, pathology [Amyotrophic Lateral Sclerosis], Molecular Biology, genetics [Tumor Necrosis Factor-alpha], Tumor Necrosis Factor-alpha, metabolism [Amyotrophic Lateral Sclerosis], Amyotrophic Lateral Sclerosis, metabolism [Motor Neurons], Motor neuron, medicine.disease, 030104 developmental biology, nervous system, Gene Expression Regulation, Astrocytes, Nerve Degeneration, biosynthesis [Glial Cell Line-Derived Neurotrophic Factor], biology.protein, genetics [Receptors, Tumor Necrosis Factor, Type I], Neuroscience, 030217 neurology & neurosurgery