المؤلفون: Guanying Wang, Zhongping Xu, Fuqiu Wang, Yuefan Huang, Yanfeng Xin, Sijia Liang, Bo Li, Huan Si, Lin Sun, Qiongqiong Wang, Xiao Ding, Xiangqian Zhu, Luo Chen, Lu Yu, Keith Lindsey, Xianlong Zhang, Shuangxia Jin

المصدر: BMC Biology, Vol 20, Iss 1, Pp 1-15 (2022)

مصطلحات موضوعية: Cotton, CRISPR/nCas9, dCas9, dCpf1, Adenine base editors (ABEs), Off-target mutations, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1741-7007

URL الوصول: https://doaj.org/article/b6d225ea9f704233ac52614f84705ea0

المؤلفون: Pablo Oppezzo, Marcelo Navarrete, Nicholas Chiorazzi

المصدر: Frontiers in Oncology, Vol 11 (2021)

مصطلحات موضوعية: AID, CLL, microenvironment, off-target mutations, SHM, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.634383/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/7a5957feabb046e49dd246d6ebcef9ad

المؤلفون: Meen Bahadur Budhthoki, Puja sharma, Saima Khan, Saroj Singh, Fu Chao, Li Yong

المصدر: International Journal of Endorsing Health Science Research, Vol 5, Iss 1, Pp 48-62 (2017)

مصطلحات موضوعية: crispr cas9, cas9, genome-editing tool, optimizing crispr cas9, off-target mutations, Medicine

وصف الملف: electronic resource

Relation: http://aeirc-edu.com/ojs14/index.php/IJEHSR/article/view/147/298; https://doaj.org/toc/2307-3748; https://doaj.org/toc/2310-3841

URL الوصول: https://doaj.org/article/02558c521fc44dd4b5c08357f9c4228b

المؤلفون: Inger B. Holme, Per L. Gregersen, Henrik Brinch-Pedersen

المصدر: Frontiers in Plant Science, Vol 10 (2019)

مصطلحات موضوعية: conventional mutagenesis, EU legislation, New Breeding Techniques (NBT), NBT mutagenesis, precision breeding, off-target mutations, Plant culture, SB1-1110

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fpls.2019.01468/full; https://doaj.org/toc/1664-462X

URL الوصول: https://doaj.org/article/d1459b13fabb45e8854fcc40e5b2b09a

المؤلفون: Bortesi, Luisa, Zhu, Changfu, Zischewski, Julia, Pérez Álvarez, Lucía, Bassie Rene, Ludovic, Nadi, Riad, Forni, Giobbe, Lade Lee, Sarah Boyd, Soto Chavarro, Erika Lorena, Jin, Xin, Medina Piles, Vicente, Villorbina Noguera, Gemma, Muñoz Gràcia, Pilar, Farré Martinez, Gemma, Fischer, Rainer, Twyman, Richard M., Capell Capell, Teresa, Christou, Paul, Schillberg, Stefan

مصطلحات موضوعية: Genome editing, Mutational signature, Off-target mutations, On-target mutations

Relation: MINECO/PN2013-2016/BIO2014-54426-P; MINECO/PN2013-2016/BIO2014-54441-P; Reproducció del document publicat a https://doi.org/10.1111/pbi.12634; Plant Biotechnology Journal, 2016, vol. 14, núm. 12, p. 2203-2216; info:eu-repo/grantAgreement/EC/FP7/269110; http://hdl.handle.net/10459.1/58835; https://doi.org/10.1111/pbi.12634

الاتاحة: http://hdl.handle.net/10459.1/58835
https://doi.org/10.1111/pbi.12634

المؤلفون: Torres-Ruiz, Raul, Rodriguez Perales, Sandra

المساهمون: Instituto de Salud Carlos III

مصطلحات موضوعية: CRISPR-Cas9 system, Cancer modelling, Gene mutations, Rearrangements, Genome engineering, ZINC-FINGER NUCLEASES, OFF-TARGET MUTATIONS, ONE-STEP GENERATION, IN-VIVO, HUMAN-CELLS, HUMAN GENOME, CHROMOSOMAL REARRANGEMENTS, CAS9 RIBONUCLEOPROTEINS, TUMOR-SUPPRESSOR, MAMMALIAN-CELLS

Relation: https://doi.org/10.3390/ijms160922151; ISI:000364541000112; Int J Mol Sci. 2015; 16(9):22151-68; http://hdl.handle.net/20.500.12105/5393; International Journal of Molecular Sciences

الاتاحة: https://hdl.handle.net/20.500.12105/5393
https://doi.org/10.3390/ijms160922151

المؤلفون: Marcelo A. Navarrete, Pablo Oppezzo, Nicholas Chiorazzi

المصدر: Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Chronic lymphocytic leukemia, Somatic hypermutation, Review, Biology, SHM, law.invention, 03 medical and health sciences, 0302 clinical medicine, law, medicine, AID, RC254-282, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cytidine deaminase, Acquired immune system, medicine.disease, microenvironment, Leukemia, 030104 developmental biology, Immunoglobulin class switching, Oncology, 030220 oncology & carcinogenesis, Cancer research, biology.protein, Suppressor, Antibody, CLL, off-target mutations

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de177d1519e6c47b8a32ae93f7acf0d
https://www.frontiersin.org/articles/10.3389/fonc.2021.634383/full

المؤلفون: Klinger, Bernhard

مصطلحات موضوعية: FOS: Veterinary science, Genome engineering, CRISPR/Cas, Off-Target Mutations, Oedema Disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::84d2a2d62d7f75b3a7d37d8111019042

المؤلفون: C. Bruce A. Whitelaw, Lluis Montoliu

المصدر: Montoliu, L & Whitelaw, C B A 2018, ' Unexpected mutations were expected and unrelated to CRISPR-Cas9 activity ', Transgenic Research, vol. 27, no. 4, pp. 315-319 . https://doi.org/10.1007/s11248-018-0081-2

مصطلحات موضوعية: 0301 basic medicine, Open science, Biology, Genome, 03 medical and health sciences, Mice, Genetic drift, Genetics, CRISPR, Animals, Cas9, Whole genome sequencing, Polymorphism, Genetic, Mouse strain, 030104 developmental biology, Mutagenesis, Mutation, Off target mutations, Animal Science and Zoology, Genome editing applications, Safety, CRISPR-Cas Systems, Agronomy and Crop Science, Biotechnology

وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b3d587d2cf91924979f5307f4a5e93c
https://pubmed.ncbi.nlm.nih.gov/29855762

المؤلفون: Raúl Torres-Ruiz, Sandra Rodriguez-Perales

المساهمون: Instituto de Salud Carlos III

المصدر: Repisalud
Instituto de Salud Carlos III (ISCIII)
International Journal of Molecular Sciences, Vol 16, Iss 9, Pp 22151-22168 (2015)
International Journal of Molecular Sciences

مصطلحات موضوعية: CRISPR-Cas9 system, Genome engineering, Carcinogenesis, Review, Gene mutation, Genome, lcsh:Chemistry, Genome editing, MAMMALIAN-CELLS, rearrangements, CRISPR, HUMAN GENOME, TUMOR-SUPPRESSOR, lcsh:QH301-705.5, Spectroscopy, IN-VIVO, Genetics, General Medicine, Computer Science Applications, Gene Targeting, Gene mutations, ONE-STEP GENERATION, Rearrangements, CHROMOSOMAL REARRANGEMENTS, Process (engineering), Cancer modelling, OFF-TARGET MUTATIONS, Computational biology, Biology, CAS9 RIBONUCLEOPROTEINS, Catalysis, Inorganic Chemistry, medicine, Animals, Humans, In patient, Physical and Theoretical Chemistry, Molecular Biology, gene mutations, cancer modelling, Models, Genetic, HUMAN-CELLS, Organic Chemistry, Cancer, medicine.disease, ZINC-FINGER NUCLEASES, lcsh:Biology (General), lcsh:QD1-999, CRISPR-Cas Systems, genome engineering

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2577cc9b9c76becd7187f6317ea8c38c
http://hdl.handle.net/20.500.12105/5393

المؤلفون: Li Yong, Meen Bahadur Budhthoki, Puja sharma, Saima Khan, Saroj Singh, Fu Chao

المصدر: International Journal of Endorsing Health Science Research, Vol 5, Iss 1, Pp 48-62 (2017)

مصطلحات موضوعية: Genome editing, optimizing crispr cas9, lcsh:R, General Engineering, crispr cas9, lcsh:Medicine, CRISPR, Computational biology, Biology, cas9, genome-editing tool, System a, off-target mutations

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b1b16226ee63fb03da6b6259ef622c
https://doi.org/10.29052/ijehsr.v5.i1.2017.48-62