يعرض 1 - 11 نتائج من 11 نتيجة بحث عن '"nsps, Non-structural proteins"', وقت الاستعلام: 0.51s تنقيح النتائج
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    المصدر: Case Studies in Chemical and Environmental Engineering, Vol 4, Iss, Pp 100105-(2021)
    Case Studies in Chemical and Environmental Engineering

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    المصدر: Journal of Molecular Structure

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    المصدر: Antiviral Research

    مصطلحات موضوعية: 0301 basic medicine, NSPs, non-structural proteins, PABPC3, Polyadenylate-binding protein 3, viruses, SARS-CoV-2, severe acute respiratory syndrome-related coronavirus 2, Antiviral drugs, COVID-19, Proteomics, Stress granules, DEAD RNA helicase, G3BP1, CoV, coronavirus, Eukaryotic Initiation Factor-2, DMVs, double-membrane vesicles, DHX, DEAH box protein, Virus Replication, Interactome, GSK3, Glycogen synthase kinase 3, HIV-1, human immunodeficiency virus type 1, DEAD-box RNA Helicases, DDX, DEAD-box helicase, Chlorocebus aethiops, ERGIC, ER-Golgi intermediate compartment, RNA, Small Interfering, Poly-ADP-Ribose Binding Proteins, Ribonucleoprotein, COVID-19, coronavirus disease 2019, biology, G3BP, Ras-GAP SH3 domain binding protein, Translation (biology), RNA Helicase A, 3. Good health, Cell biology, RNA Recognition Motif Proteins, HCV, hepatitis C virus, Host-Pathogen Interactions, RNA, Viral, antiviral drugs, COVID-19, DEAD RNA helicase, G3BP1, proteomics, stress granules, RNA Helicases, qRT-PCR, quantitative reverse transcription polymerase chain reaction, small interfering RNA, SPFQ, 030106 microbiology, SDS PAGE, Sodium Dodecyl Sulphate, YBX1, Y-box-binding protein 1, PolyAcrylamide Gel Electrophoresis, siRNA, Antiviral Agents, Article, Cell Line, 03 medical and health sciences, Stress granule, MEM, Modified Eagle Medium, Virology, SYNCRIP, Synaptotagmin Binding Cytoplasmic RNA Interacting Protein, Animals, Humans, hnRNPA1, heterogeneous nuclear ribonucleoprotein A1, Vero Cells, Pharmacology, GAPDH, Glyceraldehyde 3-phosphate dehydrogenase, LDH, Lactate dehydrogenase, SARS-CoV-2, DNA Helicases, Helicase, PP1, Protein phosphatase 1, IGF2BP, Insulin-like growth factor 2 mRNA-binding protein, Splicing factor, proline- and glutamine-rich protein, Nucleoprotein, COVID-19 Drug Treatment, 030104 developmental biology, HBV, hepatitis B virus, Viral replication, eIF, Eukaryotic initiation factor, biology.protein, TMPRSS2, transmembrane serine protease 2

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    المصدر: Bioorganic Chemistry

    مصطلحات موضوعية: 3CLpro, 3C-like protease, medicine.medical_treatment, Drug Evaluation, Preclinical, 01 natural sciences, Biochemistry, MERS-CoV, middle east respiratory syndrome coronavirus, Docking (dog), PLP, papain-like proteases, PAINS, pan assay interference compounds, Drug Discovery, BBB, blood brain barrier penetration, PDB, protein data bank, Pathogen, RMSD, root mean square difference, Coronavirus 3C Proteases, media_common, ORF, open reading frame genes, HCoV-229E, Human coronavirus 229E, Chemistry, HIA, human intestinal absorption, COVID-19, corona virus disease 2019, N, Nucleocapsid protein, Molecular Docking Simulation, DS 4.0, Discovery Studio 4.0, Biochemical evaluation, Virtual screening, Drug, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), media_common.quotation_subject, HCoV-NL63, Human coronavirus NL63, Computational biology, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Antiviral Agents, Article, ER, endoplasmic reticulum, E, envelope protein, HCoV-OC43, Human coronavirus OC43, medicine, Humans, UTR, untranslated regions, Protease Inhibitors, Molecular Biology, ComputingMethodologies_COMPUTERGRAPHICS, nsps, non-structural proteins, Protease, pp1ab, polyprotein 1ab, S, spike glycoprotein, 010405 organic chemistry, SARS-CoV-2, pp1a, polyprotein 1a, Organic Chemistry, 0104 chemical sciences, Mpro, main protease, 010404 medicinal & biomolecular chemistry, M, membrane protein, Main protease, IC50, Half maximal inhibitory concentration, HCoV-HKU1, Human coronavirus Hong Kong University 1, CYP450, cytochrome P450

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    المصدر: Gene

    مصطلحات موضوعية: TMPRSS2, Transmembrane protease serine 2, DNAH3, Dynein axonemal heavy chain 3, eQTL, Expression quantitative trait locus, DPP, Dipeptidyl peptidase, Genome-wide association study, Review, Transcriptome, NKRF, Nuclear factor-kB-repressing factor, TOM, Translocase of the outer membrane, LZTFL1, Leucine zipper transcription factor like 1, IFIT3, Interferon induced protein with tetratricopeptide repeats 3, GWAS, HDL, High-density lipoprotein, M, Membrane, NAPSA, Napsin A aspartic peptidase, Virus-host interactome analyses, TBK1, TANK binding kinase 1, TRAF, Tumor necrosis factor receptor-associated factor, General Medicine, RIPK1, Receptor-interacting serine/threonine protein kinase 1, MLKL, Mixed lineage kinase domain-like protein, PTPN22, Protein tyrosine phosphatase non-receptor type 22, MARK2, Microtubule affinity regulating kinase 2, AP-MS, Affinity purification mass spectrometry, TANK, TRAF family member associated NFKB activator, CCRL2, C-C motif chemokine receptor like 2, PRPF3, U4/U6 small nuclear ribonucleoprotein Prp3, TRAF2, TNF receptor associated factor 2, SRP, Signal recognition particle, WGS, Whole genome sequencing, CCR2, CC-chemokine receptor 2, Genetics, Humans, ApoA1, Apolipoprotein A1, KEAP1, Kelch like ECH associated protein 1, ACE2, Angiotensin converting enzyme-2, Genetic association, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, LC, Liquid chromatography, spTWAS, Splicing-transcriptome-wide association study, del, Deletion, Cryoelectron Microscopy, Computational Biology, Proteins, TWAS, Transcriptome-wide association study, S, Spike, SACM1L, SAC1 like phosphatidylinositide phosphatase, I/D, Insertion/Deletion, HGI, Host Genetics Initiative, Candidate gene, PGLS, 6-Phosphogluconolactonase, E, Envelope, PWAS, Protein-transcriptome-wide association study, IFNAR, Interferon-alpha/beta receptor, (*), STOP codon, SLC6A20, Solute carrier family 6 member 20, Crystallography, X-Ray, Interactome, Genome, XCR1, X-C motif chemokine receptor 1, PASC, Post-acute sequelae of SARS-CoV-2 infection, HLA, Human leukocyte antigens, SRPK1, SRSF protein kinase 1, XYLT1, Xylosyltransferase 1, CryoEM, Cryo-electron microscopy, N, Nucleocapsid, WNT3, Wnt family member 3, GnomAD, Genome Aggregation Database, IL, Interleukin, KIT, KIT proto-oncogene, receptor tyrosine kinase, PRSS1, Serine protease 1, ORFs, Open reading frames, PALS1, Protein associated with LIN7 1, MAGUK family member, SNP, Single nucleotide polymorphism, COVID-19, Coronavirus disease 2019, WES, Whole exome sequencing, TYK2, Tyrosine kinase 2, IFN, Type I interferons, HLA, Human leukocyte antigen, ICU, Intensive care unit, NSPs, Non-structural proteins, Host-Pathogen Interactions, SIGMAR1, Sigma nonopioid receptor 1, OAS, Oligoadenylate synthase, MBL2, Mannose-binding lectin 2, GWAS, Genome-wide association study, NSF, N-ethylmaleimide-sensitive factor, ERGIC, Endoplasmic reticulum Golgi intermediate compartment, RBD, Receptor binding domain, TWAS, TLE1, Transducin-like enhancer protein 1, PRKACA, Protein kinase A catalytic subunit alpha, Biology, Bioinformatics analysis, FYCO1, FYVE and coiled-coil domain autophagy adaptor 1, fs, Frameshift mutation, ESP, Exome Sequencing Project, LCN1P1, Lipocalin 1 pseudogene 1, Gene, GNL3, G protein nucleolar 3, Innate immune system, Host Microbial Interactions, SARS-CoV-2, PLG, Plasminogen, COVID-19, ACE, Angiotensin-converting enzyme, POFUT1, Protein O-Fucosyltransferase 1, PGES-2, Prostaglandin E synthase type 2, TLR7, Toll-like receptor 7, FOXP4, Forkhead box P4, PUF60, Poly(U)-binding-splicing factor 60, POGLUT, Protein O-glucosyltransferase 1 precursor, Genome-Wide Association Study

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    المصدر: Phytomedicine Plus
    Phytomedicine Plus, Vol 1, Iss 2, Pp 100027-(2021)

    مصطلحات موضوعية: Vero E6, African Green Monkey Kidney Epithelial-6, Huh-7, Human Hepatocellular Carcinoma-7, 3CLpro, 3C-like protease, HPLC, High-performance liquid chromatography, MOI, Multiplicity of infection, MERS, Middle east respiratory syndrome, AECOPD, Acute exacerbation of chronic obstructive pulmonary disease, Pharmacology, Other systems of medicine, IP-10, Interferon-inducible protein-10, Medicine, CCL-2/MCP-1, C-C motif ligand 2/monocyte chemoattractant protein-1, gp-130, Glycoprotein 130, HSV-1, Herpes simplex virus type 1, General Pharmacology, Toxicology and Pharmaceutics, qPCR, Quantitative PCR, media_common, MTT, Methyl Thiazolyl Tetrazolium, ERK, Extracellular signal-regulated kinase, CC50, 50% Cytotoxic concentration, IAV, Influenza A virus, HIV, Human immunodeficiency virus, mIL-6R, Membrane-bound form IL-6 Receptor, RSV, Respiratory syncytial virus, IL-8, Interleukin-8, Drug, media_common.quotation_subject, TCID50, 50% Tissue culture infective dose, COPD, Chronic obstructive pulmonary disease, Pharmacy, Article, DMSO, Dimethyl sulfoxide, mTOR, Mammalian target of rapamycin, HVJ, Hemagglutinating virus of Japan, medicine.disease, IBV, Influenza B virus, Clinical trial, CSS, Cytokine storm syndrome, Complementary and alternative medicine, RZ201-999, MIP-1β, Macrophage Inflammatory Protein-1β, IL-6R, IL-6 Receptor, MAPK, Mitogen-activated protein kinase, MOF, Multifunctional organ damage, AQP3, Aquaporins 3, PKA/p-CREB, Protein kinase A /phosphorylated cAMP response element-binding protein, nsps, Non-structural proteins, CXCL-10/IP-10, C-X-C Motif Chemokine Ligand 10/ Interferon Gamma-induced Protein 10, IFN-λ1, Interferon-λ1, Pandemic, PKB, Akt, Protein kinase B, ORFs, Open reading frames, CAT, COPD assessment test, COVID-19, Coronavirus disease 2019, Grb2, Growth factor receptor-bound protein 2, biology, LD50, 50% Lethal dose, TD50, Half-toxic dose, Cytokine storm syndrome (CSS), MLD50, 50% Minimum lethal dose, Hep-2, Human epithelial type 2, FBS, Fatal bovine serum, LH capsules, Forsythia honeysuckle (Lianhuaqingwen) capsules, CT, Computed tomography, NF-kB, Nuclear transcription factor kappa-B, M protein, Membrane protein, RT-PCR, Reverse transcription PCR, PLpro, Papain-like proteases, PI3K, Phosphoinositide 3-kinases, MDCK, Madin-darby canine kidney, Coronavirus disease 2019 (COVID-19), MCP-1, Monocyte chemotactic protein 1, PBS, Phosphate buffered saline, E protein, Envelope protein, RANTES, Regulated on activation normal T cell expressed and secreted, CPE, Cytopathic effect, PRC, People's Republic of China, Forsythia, MEK, Mitogen-activated protein kinase kinase, ACE2, Angiotensin-converting enzyme 2, ARDS, Acute respiratory distress syndrome, PHN, Phillyrin, IL-6, Interleukin-6, AIDS, Acquired immune deficiency syndrome, JAK/STAT, Janus kinase/signal transducers and activators of transcription, IC50, 50% Inhibition concentration, QC, Quality control, SARS-CoV-2, business.industry, Lianhuaqingwen, COVID-19, Forsythia honeysuckle (Lianhuaqingwen,LH) capsules, biology.organism_classification, CFDA, China Food and Drug Administration, JAK1/2, Janus kinase1/2, 3C-like protease (3CLpro), Ras, Ras GTPase, business, Cytokine storm, NHC, National Health Commission, TD0, Non-toxic Dose

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    المصدر: Biomedicine & Pharmacotherapy
    Biomedicine & Pharmacotherapy, Vol 137, Iss, Pp 111313-(2021)

    مصطلحات موضوعية: 0301 basic medicine, Coronaviruses, medicine.medical_treatment, viruses, Review, Pharmacology, chemistry.chemical_compound, 0302 clinical medicine, nsps, Non-structural proteins, Chloroquine, Medicine, CoV, Coronavirus, CQ, Chloroquine, HA, Haemagglutinin, Molecular Targeted Therapy, Enzyme Inhibitors, DAAs, Direct-acting antiviral agents, biology, FDA, US Food and Drug Administration, Therapies, Investigational, HTAs, Host-targeting antivirals, MERS-CoV, Middle East respiratory syndrome coronavirus, General Medicine, Small molecule, PIP2, Phosphatidylinositol 4,5-bisphosphate, RMP, Ribavirin monophosphate, IFN, Interferon, N, Nucleocapsid protein, COVID-19, 2019 Coronavirus disease, HIV, Human immunodeficiency virus, RBV, Ribavirin, NIAID, National Institute of Allergy and Infectious Diseases, 030220 oncology & carcinogenesis, 6MP, 6-Mercaptopurine, BSAs, Broad-spectrum antiviral drugs, RDP, Ribavirin diphosphate, EBOV, Ebola virus, Transmembrane serine protease (TMPRSS2), GTP, Guanosine triphosphate, medicine.drug, 3CLpro, 3C-Like protease, DHODH, Dihydroorotate dehydrogenase, 6TG, 6-Thioguanine, Papain-like protease (PLpro), TGN, Trans-Golgi network, RM1-950, Favipiravir, TMPRSS2, HyCoSuL, Hybrid Combinatorial Substrate Library, Antiviral Agents, PP2A, Protein phosphatase 2A, SARS-CoV, Severe acute respiratory syndrome coronavirus, WHO, World Health Organization, CPE, Cytopathic effect, PLpro, Papain-like protease, 03 medical and health sciences, EUA, Emergency use authorization, IRF3, Interferon regulatory factor 3, SAR, Structure-activity relationship, ACE2, Angiotensin-converting enzyme 2, S, Spike protein, SKP2, S-Phase kinase-associated protein 2, Humans, RdRp, RNA-dependent RNA polymerase, RTP, Ribavirin triphosphate, BECN1, Beclin1, ComputingMethodologies_COMPUTERGRAPHICS, Serine protease, SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2, Protease, HC, QHydroxychloroquine, business.industry, SARS-CoV-2, Ribavirin, fungi, COVID-19, PC, Pro-protein convertase, DHO, Dihydroorotate, M, Membrane protein, RNA-dependent RNA polymerase (RdRp), COVID-19 Drug Treatment, AMPK, AMP-activated protein kinase, CMK, Decanoyl-RVKR-chloromethylketone, Mpro, Main protease, 030104 developmental biology, chemistry, 3C-like protease (3CLpro), E, Envelope protein, biology.protein, Dihydroorotate dehydrogenase, GM1, Monosialotetrahexosylganglioside 1, LPV/r, Lopinavir/ritonavir, Therapeutics. Pharmacology, ELs, Endolysosomes, business, IMPDH, Inosine monophosphate dehydrogenase

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    المؤلفون: Gurung, Arun Bahadur

    المصدر: Gene Reports

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    المصدر: Journal of Molecular Biology
    Journal of Molecular Biology, 429(22), 3441-3470

    مصطلحات موضوعية: 0301 basic medicine, ssRNA, single-stranded RNA, eIF4G, eukaryotic translation initiation factor 4 gamma, OTU, ovarian tumor protease, CoV, coronavirus, ERVV, Erve virus, BL2, blocking-loop 2, RIG-I, retinoic acid-inducible gene I, IRF, IFN regulatory factor, innate immune evasion, Deubiquitinating enzyme, cGAS, cyclic-GMP-AMP synthase, PEDV, porcine epidemic diarrhea virus, Ubiquitin, Structural Biology, CCHFV, Crimean-Congo hemorrhagic fever virus, TRAF, TNF receptor-associated factor, MERS-CoV, Middle East respiratory syndrome CoV, viral deubiquitinating enzyme, Ub, ubiquitin, MCMV, murine cytomegalovirus, TNF, tumor necrosis factor, Deubiquitinating Enzymes, RIG-I, ISG15, interferon-stimulated gene 15, Cell biology, DUB, deubiquitinating enzyme, LDV, lactate dehydrogenase-elevating virus, TYMV, turnip yellow mosaic virus, Host-Pathogen Interactions, Viruses, MAVS, mitochondrial antiviral signaling protein, EBV, Epstein–Barr virus, MDA5, melanoma differentiation factor 5, HSV-1, herpes simplex virus 1, IRF3, IFN regulatory factor 3, SARS-CoV, severe acute respiratory syndrome CoV, PRR, pattern-recognition receptor, papain-like protease, UbV, Ub variant, Biology, TF, trans frame, EAV, equine arteritis virus, Article, PLP, papain-like protease, 03 medical and health sciences, Viral Proteins, Immune system, STING, stimulator of IFN genes, ORF, open reading frame, ubiquitin, ISG, interferon-stimulated gene, IBV, avian infectious bronchitis virus, UBL, Ub-like, IFN, interferon, SARS, severe acute respiratory syndrome, CRL, Cullin-RING Ub ligase, AMC, 7-amino-4-methylcoumarin, TLR, toll-like receptor, Molecular Biology, MHV, mouse hepatitis virus, RR, ribonucleotide reductase, HAUSP, herpesvirus-associated USP, NSDV, Nairobi sheep disease virus, Immune Evasion, KSV, Kaposi's sarcoma virus, AdV, adenovirus, HCMV, human cytomegalovirus, nsps, non-structural proteins, Innate immune system, 030102 biochemistry & molecular biology, NEMO, NF-κB essential modulator, USP, Ub-specific protease, MERS, Middle East respiratory syndrome, DUGV, Dugbe virus, SHFV, simian hemorrhagic fever virus, cGAMP, cyclic-GMP-AMP, MDV, Marek's disease virus, ISG15, Virology, TGEV, porcine transmissible gastroenteritis, Protein ubiquitination, Immunity, Innate, TANK, TRAF family member-associated activator, PRRSV, porcine reproductive and respiratory syndrome virus, 030104 developmental biology, Viral replication, TBK1, TANK-binding kinase 1, biology.protein, FMDV, foot-and-mouth disease virus, EVG, Enterovirus species G

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