المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/journal_contribution/Definition_of_topology_/16686167

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s004

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/journal_contribution/Parameters_used_to_calculate_the_manual_evaluation_measure_MEM_/16686170

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s005

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/journal_contribution/Exemplary_MEM_analysis_of_the_dmb_BGC_/16686182

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s009

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/journal_contribution/Step-by-step_explanation_for_the_manual_interpretation_of_the_FunOrder_output_/16686185

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s010

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/journal_contribution/Exemplary_interpretation_of_the_FunOrder_output_of_an_unknown_fungal_BGC_1_/16686188

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s011

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/journal_contribution/Exemplary_interpretation_of_the_FunOrder_output_of_an_unknown_fungal_BGC_2_/16686191

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s012

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/journal_contribution/ANOVA_for_the_ICQ_values_of_the_control_and_tests_GCs_and_protein_sets_respectively_/16686194

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s013

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/journal_contribution/FunOrder_output_of_the_Lovastatin_BGC_from_i_A_i_i_terreus_i_lov_/16686197

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s014

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/dataset/Protein_sets_of_conserved_metabolic_pathways_of_the_primary_metabolism_/16686161

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s002

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/dataset/Empirically_tested_BGCs_used_as_control_set_in_this_study_/16686158

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s001

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/dataset/Sequential_GCs_used_in_this_study_/16686164

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s003

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/dataset/Random_GCs_used_in_this_study_/16686179

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s008

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/dataset/Calculation_of_MEM_values_for_positive_control_BGCs_/16686173

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.s006

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/figure/Schematic_representation_of_the_workflow_of_FunOrder_/16686203

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.g002

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/figure/Schematic_representation_of_the_lovastatin_BGC_from_i_Aspergillus_terreus_i_lov_/16686200

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.g001

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/figure/Kernel_density_plot_of_the_ICQ_values_for_co-evolutionary_linked_enzymes_of_different_control_sets_/16686206

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.g003

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/figure/A_selection_of_the_standard_output_of_the_FunOrder_analysis_of_the_lovastatin_BGC_lov_/16686209

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.g004

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/dataset/Fungal_proteomes_included_in_the_empirically_optimized_database_/16686215

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.t001

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/figure/Kernel_density_plots_of_the_relative_discovery_rate_of_essential_or_biosynthetic_genes_in_30_tested_fungal_BGCs_/16686212

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.g005

المؤلفون: Gabriel A. Vignolle (8628246), Denise Schaffer (11485499), Leopold Zehetner (11485502), Robert L. Mach (1298775), Astrid R. Mach-Aigner (8628249), Christian Derntl (3457853)

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Pharmacology, Evolutionary Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, suitable proteome database, genomic data available, facilitate heterologous expression, biosynthetic gene clusters, different output formats, distinguishing essential genes, computational molecular co, bgcs may contain, called gap genes, essential biosynthetic genes, evolution , essential genes, gap genes, biosynthetic pathway, different structures, vast group, transcriptome analyses, phylogenetic tree, novel plastics, native hosts

Relation: https://figshare.com/articles/dataset/Statistical_evaluation_of_the_performance_of_FunOrder_in_detecting_relevant_genes_in_BGCs_/16686221

الاتاحة: https://doi.org/10.1371/journal.pcbi.1009372.t003