المؤلفون: Peng Zhang, Hao Li, Qingxin Ma, Tianzeng Chen, Biwu Chu, Yunbo Yu, Hong He

مصطلحات موضوعية: Medicine, Physiology, Ecology, Sociology, Inorganic Chemistry, Space Science, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, reactive centers driving, rapidly deactivated due, functionalized elemental carbon, despite extensive studies, surface reactive sites, air pollution chemistry, key contributing factor, 2 , surface reduction reactivity, surface conversion, polluted air, work suggests, significant role, significant effect, reductive capacity, rapid deactivation, present understanding, oh groups, novel mechanism, notably accelerate, finding challenges, existing notion

Relation: https://figshare.com/articles/journal_contribution/SO_sub_2_sub_Photoaging_Enhances_the_Surface_Conversion_of_NO_sub_2_sub_to-HONO_on_Elemental_Carbon/24982140

الاتاحة: https://doi.org/10.1021/acs.estlett.3c00878.s001
https://figshare.com/articles/journal_contribution/SO_sub_2_sub_Photoaging_Enhances_the_Surface_Conversion_of_NO_sub_2_sub_to-HONO_on_Elemental_Carbon/24982140

المؤلفون: Glen E. Cronan, Andrei Kuzminov

مصطلحات موضوعية: Biochemistry, Microbiology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, ” induction response, whereas others appeared, usually within minutes, nearly perfect “, mediate quick depletion, demonstrated excellent control, characterize cellular responses, apparently novel mechanism, expression vectors containing, previously characterized system, purpose degron tool, controlled protein degradation, sspb system present, degron substrates proved, expression vehicles, degron system, promoted degradation, catalyzed degradation, several degron, degron tagging, widespread adoption, uniquely useful, titratable sspb

Relation: https://figshare.com/articles/journal_contribution/Degron-Controlled_Protein_Degradation_in_Escherichia_coli_New_Approaches_and_Parameters/25150816

الاتاحة: https://doi.org/10.1021/acssynbio.3c00768.s001
https://figshare.com/articles/journal_contribution/Degron-Controlled_Protein_Degradation_in_Escherichia_coli_New_Approaches_and_Parameters/25150816

المؤلفون: Vitor Martins de Freitas Amorim, Eduardo Pereira Soares, Anielle Salviano de Almeida Ferrari, Davi Gabriel Salustiano Merighi, Robson Francisco de Souza, Cristiane Rodrigues Guzzo, Anacleto Silva de Souza

المصدر: Viruses, Vol 16, Iss 6, p 844 (2024)

مصطلحات موضوعية: SARS-CoV-2, 3CLpro, novel mechanism of catalysis, preclinical and clinical trials, triad, Microbiology, QR1-502

Relation: https://www.mdpi.com/1999-4915/16/6/844; https://doaj.org/toc/1999-4915; https://doaj.org/article/609c5f7129494b0c86459b5ef37c3585

الاتاحة: https://doi.org/10.3390/v16060844
https://doaj.org/article/609c5f7129494b0c86459b5ef37c3585

المؤلفون: Luisa I. Beyer, Ann-Britt Schäfer, Agustina Undabarrena, Inger Mattsby-Baltzer, Daniel Tietze, Elin Svensson, Alexandra Stubelius, Michaela Wenzel, Beatriz Cámara, Alesia A. Tietze

مصطلحات موضوعية: Biophysics, Biochemistry, Biotechnology, Immunology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, qualified hit sequence, novel mechanism allowing, several nonribosomal peptides, peptides potentially act, mimicking nonribosomal peptides, including cyclic peptides, marine actinomycetota isolated, cell membrane via, genome mining predictions, bioactivity including mode, action studies suggest, eight peptides, membrane potential, marine environment, future studies, study shows, streptomyces sp, small ions, potent amps, nmr spectroscopy, effective sources, dramatic influence, chemically synthesized

Relation: https://figshare.com/articles/journal_contribution/Mimicking_Nonribosomal_Peptides_from_the_Marine_Actinomycete_Streptomyces_sp_H_KF8_Leads_to_Antimicrobial_Peptides/24867308

الاتاحة: https://doi.org/10.1021/acsinfecdis.3c00206.s001
https://figshare.com/articles/journal_contribution/Mimicking_Nonribosomal_Peptides_from_the_Marine_Actinomycete_Streptomyces_sp_H_KF8_Leads_to_Antimicrobial_Peptides/24867308

المؤلفون: Chengkuan Zhao, Qianhua Luo, Jianxiang Huang, Siman Su, Lijuan Zhang, Danling Zheng, Meini Chen, Xinyue Lin, Jialin Zhong, Li Li, Kai Ling, Shuyao Zhang

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Physiology, Pharmacology, Immunology, Cancer, Hematology, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, novel mechanism underlying, experimental results confirmed, current study aims, 150 – 5p, induced organ dysfunction, noted low expression, extracellular vesicles derived, evs transferred mir, induced ali, vivo <, therapeutic benefit, target cells, suppressive role, subsequently cocultured, proinflammatory cytokines, paracrine effects

Relation: https://figshare.com/articles/journal_contribution/Extracellular_Vesicles_Derived_from_Human_Adipose-Derived_Mesenchymal_Stem_Cells_Alleviate_Sepsis-Induced_Acute_Lung_Injury_through_a_MicroRNA-150_5p-Dependent_Mechanism/24915272

الاتاحة: https://doi.org/10.1021/acsbiomaterials.3c00614.s001
https://figshare.com/articles/journal_contribution/Extracellular_Vesicles_Derived_from_Human_Adipose-Derived_Mesenchymal_Stem_Cells_Alleviate_Sepsis-Induced_Acute_Lung_Injury_through_a_MicroRNA-150_5p-Dependent_Mechanism/24915272

المؤلفون: Nong, Caiyong, Li, Xiaodong, Koivula, Risto, Xu, Junhua, Szlachta, Małgorzata

المساهمون: Department of Chemistry, Ion exchange for nuclear waste treatment and for recycling, Doctoral Programme in Materials Research and Nanosciences, Doctoral Programme in Chemistry and Molecular Sciences

مصطلحات موضوعية: Caesium sorption, Vacancies, Titanium hexacyanoferrate, Sorption-surface complexation model, Novel mechanism, Chemical sciences

وصف الملف: application/pdf

Relation: Nong , C , Li , X , Koivula , R , Xu , J & Szlachta , M 2023 , ' New insights into the mechanism of cesium sorption on titanium hexacyanoferrate: Experimental findings and model development ' , Chemical Engineering Journal , vol. 477 , 147134 . https://doi.org/10.1016/j.cej.2023.147134; RIS: urn:E5FF34478B381050D32A7641F25052D5; http://hdl.handle.net/10138/568690; 85178175495; 001110446600001

الاتاحة: http://hdl.handle.net/10138/568690

المؤلفون: Jianan Zhao, Shicheng Guo, Steven J. Schrodi, Dongyi He

المصدر: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

مصطلحات موضوعية: hyperuricemia, gout, genetic susceptibility loci, novel mechanism, inflammation introduction, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2022.937855/full; https://doaj.org/toc/2296-634X

URL الوصول: https://doaj.org/article/65d35c2236214dd0afe239a3ae8abb5d

المؤلفون: Kong Yuan, Huang Xiaojun

المصدر: 生物医学转化, Vol 1, Iss 1, Pp 21-25 (2020)

مصطلحات موضوعية: bone marrow failure diseases, bone marrow microenvironment, hematopoietic regulation, novel mechanism, novel intervention, Medicine, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://swyxzh.ijournals.cn/swyxzh/article/html/20200104?st=article_issue; https://doaj.org/toc/2096-8965

URL الوصول: https://doaj.org/article/cba9c76a0b0a4be4b6c7e0be498d3547

المؤلفون: Qureshi Sajid Ahmed, Ramesh Kumar M., Prakash C.

المصدر: AUTEX Research Journal, Vol 21, Iss 4, Pp 352-362 (2020)

مصطلحات موضوعية: rapier loom, false selvedge, novel mechanism, hard waste, quality, Textile bleaching, dyeing, printing, etc., TP890-933

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2300-0929

URL الوصول: https://doaj.org/article/a3d7ba079dcb45489f9772ae47254ea3

المؤلفون: Edruce Edouarzin, Connor Horn, Anuja Paudyal, Cunli Zhang, Jianyu Lu, Zongbo Tong, Guri Giaever, Corey Nislow, Raja Veerapandian, Duy H. Hua, Govindsamy Vediyappan

المصدر: Microbial Cell, Vol 7, Iss 6, Pp 146-159 (2020)

مصطلحات موضوعية: drimenol, synthesis, candida albicans, candida auris, saccharomyces cerevisiae, fungicidal antifungal, novel mechanism of action, crk1 kinase associated, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://microbialcell.com/researcharticles/2020a-edouarzin-microbial-cell/; https://doaj.org/toc/2311-2638

URL الوصول: https://doaj.org/article/f193f4e55ab2425398e6b4425e456702

المؤلفون: Xin Xu (11989), Zhenyang Lin (1463215)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Biotechnology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, renewable biomass conversion, metal center prior, density functional theory, >- heterocyclic carbene, dft results reveal, aromatic c –, c –, useful molecules, room temperature, reaction mechanism, phenyl nucleophile, oxidative addition, opening reaction, novel mechanism, n <, involves mg, ii )–, great potential, detailed mechanism, coordination followed, complex catalyzing

Relation: https://figshare.com/articles/journal_contribution/Understanding_the_Reaction_Mechanism_of_Nickel-Catalyzed_Enantioselective_Arylative_Activation_of_the_Aromatic_C_O_Bond/21762703

الاتاحة: https://doi.org/10.1021/acs.organomet.2c00542.s001

المؤلفون: Karniza Khalid, Raja Elina Afzan Raja Ahmad, Sze Yee Lui, Alwin Yu Hoong Tong, Ida Zaliza Zainal Abidin

مصطلحات موضوعية: Hypotension, Myocardial Infarction, Streptokinase, Retrospective, Analysis, Novel Mechanism

Relation: https://zenodo.org/communities/nccr_icr; https://doi.org/10.5281/zenodo.4004990; https://doi.org/10.5281/zenodo.4004991; oai:zenodo.org:4004991

الاتاحة: https://doi.org/10.5281/zenodo.4004991

المؤلفون: Qiushuang Sun (11202521), Qun Niu (151870), Yating Guo (9403369), Yu Zhuang (2824982), Xiaonan Li (340228), Jia Liu (41593), Ning Li (45258), Zhiyu Li (10983), Fang Huang (154302), Zhixia Qiu (5535824)

مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Physiology, Pharmacology, Biotechnology, Cancer, Virology, Chemical Sciences not elsewhere classified, Novel Mechanism Mediating, attenuate lipid accumulation, plasma membrane citrate transporter, SLC 13A mitochondrial citrate carrier, hepatic lipid deposition, ACLY, Inhibiting SLC 13A, AMPK, Curcumin, OPA-stimulated HepG 2 cells, DNL, NAFLD, Cytoplasmic citrate flux, HepG 2 cells, 25A, HFHFD, SLC 13A, HEK 293T cells transfected, ATP-dependent citrate lyase

Relation: https://figshare.com/articles/journal_contribution/Regulation_on_Citrate_Influx_and_Metabolism_through_Inhibiting_SLC13A5_and_ACLY_A_Novel_Mechanism_Mediating_the_Therapeutic_Effects_of_Curcumin_on_NAFLD/15073493

الاتاحة: https://doi.org/10.1021/acs.jafc.1c03105.s001

المؤلفون: Jia-Hong Huang (9437654), Yubing Si (1617748), Xi-Yan Dong (1650169), Zhao-Yang Wang (302378), Li-Ying Liu (105436), Shuang-Quan Zang (1411888), Thomas C. W. Mak (7286414)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Physiology, Evolutionary Biology, Immunology, Developmental Biology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, chiroptical activity, dodecahedral shell, Fullerene-like Metal Nanoclusters, Ag 13, copper-doped Ag 13, chiral Ag 13, chirality generation, novel mechanism, Cu doping, Ag 20 nanocluster, metal nanoclusters, propylene oxide, space group P 2 1 2 1 2 1, acetonitrile ligands, core-based CD response, all-thiolated Ag 13

Relation: https://figshare.com/articles/journal_contribution/Symmetry_Breaking_of_Atomically_Precise_Fullerene-like_Metal_Nanoclusters/15125125

الاتاحة: https://doi.org/10.1021/jacs.1c05568.s001

المؤلفون: Biao Lu (1342371), Dong Liu (115204), Bin Gui (542725), Jun Gou (2631100), Huaide Dong (11558667), Qiyue Hu (1963867), Jun Feng (116162), Yuchang Mao (11558670), Xiaodong Shen (1542499), Shenglan Wang (9611464), Caihua Zhang (1802497), Ru Shen (1758649), Yinfa Yan (3005082), Lei Chen (54296), Huiyun Wang (3711682), Di Li (335947), Jiayin Zhang (1850089), Minsheng Zhang (2403979), Rumin Zhang (2729599), Chang Bai (2356918), Feng He (47348), Weikang Tao (2428648), Suxing Liu (1427581)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, subtle structural differences, scaffold hopping based, functional drug target, first comprehensive work, activating anticancer agent, 2 ‑( ortho, elicit antitumor efficacy, opposite biological moa, antitumor activity rorγ, 17 , antitumor efficacy, vivo <, rorγ agonist, tumor tissues, rational optimization, pharmacokinetic profile, novel mechanism, compounds led, cancer immunity, also promotion

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_2_Ortho-Substituted_Benzyl_-Indole_Derivatives_as_Potent_and_Orally_Bioavailable_ROR_Agonists_with_Antitumor_Activity/16803747

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00828.s001

المؤلفون: Christopher J. Zerio (11595690), Tyler A. Cunningham (11436311), Allison S. Tulino (11595693), Erin A. Alimusa (11595696), Thomas M. Buckley (11595699), Kohlson T. Moore (11595702), Matthew Dodson (4388749), Nathan C. Wilson (11595705), Andrew J. Ambrose (4230583), Taoda Shi (6156134), Jared Sivinski (11595708), Derek J. Essegian (11595711), Donna D. Zhang (261086), Stephan C. Schürer (1456285), Jonathan H. Schatz (11595714), Eli Chapman (594753)

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Cancer, Hematology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, promising intersection point, many oncogenic pathways, inhibits unwinding activity, functional assays uncovered, eif )­ 4a, suppressing atp hydrolysis, proper rna binding, eukaryotic initiation factor, 28 , novel eif4a inhibitor, uncompetitive inhibitor, novel pocket, novel mechanism, eif4a inhibitor, start codon, rna groove, powered dead, pharmaceutical target, molecular docking, malignant growth, intriguing hit

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_an_eIF4A_Inhibitor_with_a_Novel_Mechanism_of_Action/16856187

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01014.s001

المؤلفون: Varsha Thakur (11099063), Juliano Tiburcio de Freitas (11099066), Yuan Li (67017), Keman Zhang (10718040), Alyssa Savadelis (11099069), Barbara Bedogni (11099072)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, breast cancer cells, MT 1-MMP, cancer patients, laminB 1, Stable laminB 1, FAK, laminB 1 expression rescues replica., mediates replication fork, matrix metalloproteinase MT 1-MMP, breast cancer, replication fork, chemotherapy resistance, envelope protein laminB 1, MT 1-MMP inhibition, RF degradation, DNA damage, novel mechanism, MT 1-MMP ECM processing, laminB 1 stability, replication forks, extracelluar matrix

Relation: https://figshare.com/articles/journal_contribution/FAK_and_laminB1_co-localize_at_the_nuclear_rim_in_shGFP_expressing_cells_/14934260

الاتاحة: https://doi.org/10.1371/journal.pone.0253062.s001

المؤلفون: Varsha Thakur (11099063), Juliano Tiburcio de Freitas (11099066), Yuan Li (67017), Keman Zhang (10718040), Alyssa Savadelis (11099069), Barbara Bedogni (11099072)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, breast cancer cells, MT 1-MMP, cancer patients, laminB 1, Stable laminB 1, FAK, laminB 1 expression rescues replica., mediates replication fork, matrix metalloproteinase MT 1-MMP, breast cancer, replication fork, chemotherapy resistance, envelope protein laminB 1, MT 1-MMP inhibition, RF degradation, DNA damage, novel mechanism, MT 1-MMP ECM processing, laminB 1 stability, replication forks, extracelluar matrix

Relation: https://figshare.com/articles/journal_contribution/S2_Fig_-/14934263

الاتاحة: https://doi.org/10.1371/journal.pone.0253062.s002

المؤلفون: Varsha Thakur (11099063), Juliano Tiburcio de Freitas (11099066), Yuan Li (67017), Keman Zhang (10718040), Alyssa Savadelis (11099069), Barbara Bedogni (11099072)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, breast cancer cells, MT 1-MMP, cancer patients, laminB 1, Stable laminB 1, FAK, laminB 1 expression rescues replica., mediates replication fork, matrix metalloproteinase MT 1-MMP, breast cancer, replication fork, chemotherapy resistance, envelope protein laminB 1, MT 1-MMP inhibition, RF degradation, DNA damage, novel mechanism, MT 1-MMP ECM processing, laminB 1 stability, replication forks, extracelluar matrix

Relation: https://figshare.com/articles/journal_contribution/S1_Raw_images_-/14934275

الاتاحة: https://doi.org/10.1371/journal.pone.0253062.s005

المؤلفون: Yuying Fang (7479167), Xiucai Chen (10757923), Qingyun Tan (6069671), Huihao Zhou (3135732), Jun Xu (45543), Qiong Gu (562902)

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, bioavailable intracellular ferrous iron, oxidative cell death, iron-dependent form, ferroptosis inhibitors, ferroptosis inhibitor 9, New Mechanism, cargo receptor, ischemic-refusion injury, ischemic stroke, Inhibiting Ferroptosis, Action Ferroptosis, ligand 9, NCOA 4, FTH, receptor coactivator 4, drug target, Compound 9, novel mechanism

Relation: https://figshare.com/articles/journal_contribution/Inhibiting_Ferroptosis_through_Disrupting_the_NCOA4_FTH1_Interaction_A_New_Mechanism_of_Action/14551159

الاتاحة: https://doi.org/10.1021/acscentsci.0c01592.s001