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1Academic JournalSynthesis and biochemical evaluation of warhead-decorated psoralens as (immuno)proteasome inhibitors
المؤلفون: Shannon Schiffrer, Eva, Proj, Matic, Gobec, Martina, Rejc, Luka, Šterman, Andrej, Mravljak, Janez, Gobec, Stanislav, Sosič, Izidor
المصدر: Molecules, vol. 26, no. 2, 356, 2021. ; ISSN: 1420-3049
مصطلحات موضوعية: immunoproteasome, psoralen core, non-peptidic, electrophilic compounds, warhead scan, imunopreoteasom, zaviralci, psoralen, avtoimunske bolezni, farmacevtska kemija, info:eu-repo/classification/udc/615.4:54:616-097
وصف الملف: application/pdf; text/url
Relation: info:eu-repo/grantAgreement/ARRS//P1-0208; info:eu-repo/grantAgreement/ARRS//N1-0068; info:eu-repo/grantAgreement/ARRS//J3-1745; https://repozitorij.uni-lj.si/IzpisGradiva.php?id=134920; https://repozitorij.uni-lj.si/Dokument.php?id=153664&dn=; https://repozitorij.uni-lj.si/Dokument.php?id=153663&dn=; https://plus.cobiss.net/cobiss/si/sl/bib/46540803; http://hdl.handle.net/20.500.12556/RUL-134920
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2Academic Journal
المؤلفون: Pla López, Alberto, Castillo, Raquel, Cejudo Marín, Rocío, García Pedrero, Olaya, Bakir Laso, Mariam, Falomir, Eva, Miguel Carda
مصطلحات موضوعية: PD-L1, VEGFR-2, c-Myc, multitarget inhibitors, immunomodulation, angiogenesis, non-peptidic small molecules, flow cytometry
وصف الملف: application/pdf
Relation: Int. J. Mol. Sci. 2022, 23(13); Pla-López, A.; Castillo, R.; Cejudo-Marín, R.; García-Pedrero, O.; Bakir-Laso, M.; Falomir, E.; Carda, M. Synthesis and Biological Evaluation of Small Molecules as Potential Anticancer Multitarget Agents. Int. J. Mol. Sci. 2022, 23, 7049. https://doi.org/10.3390/ ijms23137049; http://hdl.handle.net/10234/200217; https://doi.org/10.3390/ijms23137049
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3Academic JournalSynthesis and Biochemical Evaluation of Warhead-Decorated Psoralens as (Immuno)Proteasome Inhibitors
المؤلفون: Eva Shannon Schiffrer, Matic Proj, Martina Gobec, Luka Rejc, Andrej Šterman, Janez Mravljak, Stanislav Gobec, Izidor Sosič
المصدر: Molecules; Volume 26; Issue 2; Pages: 356
مصطلحات موضوعية: immunoproteasome, psoralen core, non-peptidic, electrophilic compounds, warhead scan
جغرافية الموضوع: agris
وصف الملف: application/pdf
Relation: Natural Products Chemistry; https://dx.doi.org/10.3390/molecules26020356
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4Academic Journal
المؤلفون: Rodrigo A. Nava Lara, Longendri Aguilera-Mendoza, Carlos A. Brizuela, Antonio Peña, Gabriel Del Rio
المصدر: Molecules; Volume 24; Issue 7; Pages: 1258
مصطلحات موضوعية: machine-learning, antimicrobial peptide, non-peptidic antimicrobial compound, antimicrobial activity
جغرافية الموضوع: agris
وصف الملف: application/pdf
Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules24071258
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5Academic Journal
المؤلفون: Sina Bavari, Cary J. Retterer, Edna Torres-Melendez, Sarah J. Sandwick, Laura M. Wanner, Lyal E. Tressler, Jonathan E. Nuss, Gordon Ruthel, James C. Burnett
المصدر: Toxins, Vol 3, Iss 3, Pp 207-217 (2011)
مصطلحات موضوعية: botulinum neurotoxin, small molecule non-peptidic inhibitor, neutralizing antibody, Bafilomycin A1, Medicine
وصف الملف: electronic resource
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6
المؤلفون: Konieczny, Adam
مصطلحات موضوعية: 615 Pharmazie, NPY Y4 receptor, non-peptidic ligands, antagonists, cyclic peptides, ddc:615
وصف الملف: application/pdf
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7Dissertation/ Thesis
المؤلفون: Scanlon, James J
مصطلحات موضوعية: Cancer studies, Chemistry, breast-cancer, non-peptidic, kisspeptins, KISS1R, antagonist, drug-discovery
وصف الملف: text
Relation: https://eprints.kingston.ac.uk/id/eprint/53683/1/Scanlon-J.pdf; Scanlon, James J (2022) Design and synthesis of novel non-peptidic KISS1R antagonists to restore drug sensitivity to triple-negative breast cancer patients. (MSc(R) thesis), Kingston University, .
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8Academic Journal
المؤلفون: Bonini, C, Chiummiento, L., Di Blasio, N., Funicello, M., Lupattelli, P., Tramutola, F., Miertus, S., Frecer, V., Kong, D. X., BERTI, FEDERICO, OSTRIC, ADRIAN
المساهمون: Bonini, C, Chiummiento, L., Di Blasio, N., Funicello, M., Lupattelli, P., Tramutola, F., Berti, Federico, Ostric, Adrian, Miertus, S., Frecer, V., Kong, D. X.
مصطلحات موضوعية: HIV PR inhibitor, Indole, Non-peptidic inhibitor, Dose-Response Relationship, Drug, HIV Protease, HIV Protease Inhibitors
وصف الملف: STAMPA
Relation: info:eu-repo/semantics/altIdentifier/pmid/25074848; info:eu-repo/semantics/altIdentifier/wos/WOS:000341293300030; volume:22; issue:17; firstpage:4792; lastpage:4802; numberofpages:11; journal:BIOORGANIC & MEDICINAL CHEMISTRY; http://hdl.handle.net/11368/2842480; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84906936204
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9Synthesis and Biochemical Evaluation of Warhead-Decorated Psoralens as (Immuno)Proteasome Inhibitors
المؤلفون: Martina Gobec, Matic Proj, Eva Shannon Schiffrer, Stanislav Gobec, Luka Rejc, Janez Mravljak, Izidor Sosič, Andrej Šterman
المصدر: Molecules, Vol 26, Iss 356, p 356 (2021)
Molecules
Molecules, vol. 26, no. 2, 356, 2021.
Volume 26
Issue 2مصطلحات موضوعية: Models, Molecular, Proteasome Endopeptidase Complex, Magnetic Resonance Spectroscopy, electrophilic compounds, Protein subunit, medicine.medical_treatment, non-peptidic, Pharmaceutical Science, 01 natural sciences, Article, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, immunoproteasome, lcsh:Organic chemistry, Furocoumarins, Drug Discovery, medicine, Physical and Theoretical Chemistry, Psoralen, warhead scan, 030304 developmental biology, 0303 health sciences, Protease, zaviralci, udc:615.4:54:616-097, 010405 organic chemistry, imunopreoteasom, Organic Chemistry, Cancer, medicine.disease, avtoimunske bolezni, Chemical space, 0104 chemical sciences, Haematopoiesis, Warhead, Biochemistry, chemistry, Proteasome, Chemistry (miscellaneous), farmacevtska kemija, Molecular Medicine, psoralen core, psoralen, Peptides, Proteasome Inhibitors
وصف الملف: application/pdf; text/url
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10Dissertation/ Thesis
المؤلفون: Appiah Kubi, George
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11
المؤلفون: Longendri Aguilera-Mendoza, Rodrigo A Nava Lara, Antonio Peña, Carlos A. Brizuela, Gabriel del Rio
المصدر: Molecules
Volume 24
Issue 7
Molecules, Vol 24, Iss 7, p 1258 (2019)مصطلحات موضوعية: antimicrobial peptide, medicine.drug_class, Antibiotics, Antimicrobial peptides, Pharmaceutical Science, Heterologous, Microbial Sensitivity Tests, Biology, Machine learning, computer.software_genre, Article, Analytical Chemistry, lcsh:QD241-441, Machine Learning, 03 medical and health sciences, Human health, lcsh:Organic chemistry, Anti-Infective Agents, Drug Discovery, medicine, Humans, Physical and Theoretical Chemistry, non-peptidic antimicrobial compound, 030304 developmental biology, 0303 health sciences, Training set, antimicrobial activity, Bacteria, 030306 microbiology, business.industry, Organic Chemistry, machine-learning, Human microbiome, Antimicrobial, Gastrointestinal Microbiome, Chemistry (miscellaneous), Molecular Medicine, Identification (biology), Artificial intelligence, business, computer
وصف الملف: application/pdf
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12Academic Journal
المصدر: CHIMIA, Vol 54, Iss 11 (2000)
مصطلحات موضوعية: Molecular recognition, Non-peptidic inhibitors, Pharmaceutical chemistry, Structure-based design, Thrombin, Chemistry, QD1-999
وصف الملف: electronic resource
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13Academic Journal
المصدر: CHIMIA; Bd. 54 Nr. 11 (2000): Pharmaceutical Chemistry; 633 ; CHIMIA; Vol. 54 No. 11 (2000): Pharmaceutical Chemistry; 633 ; 2673-2424 ; 0009-4293
مصطلحات موضوعية: Molecular recognition, Non-peptidic inhibitors, Pharmaceutical chemistry, Structure-based design, Thrombin
وصف الملف: application/pdf
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14Academic Journal
المؤلفون: Κοτζαμπασάκη, Βασιλική
المساهمون: Στρατάκης, Μανώλης, Ορφανόπουλος, Μιχαήλ, Κατερινόπουλος, Χαράλαμπος, Βασιλικογιαννάκης, Γεώργιος, Σμόνου, Ιουλία, Ηλιόπουλος, Αριστείδης, Σπύρος, Απόστολος
مصطلحات موضوعية: Διεγερμένο μοριακό οξυγόνο απλής κατάστασης (1Ο2), Φωτοξείδωση φουρανίων, Smac/Diablo, AVPI, Μη πεπτιδικές ενώσεις-μιμητες AVPI, Δικυκλικές γ-λακτάμες, γ-υδροξυβουτενολίδια, 2-θειοφαίνυλο φουράνια, Βιομιμητική σύνθεση, Αντίδραση Diels-Alder, Selectivity, Singlet oxygen, Furan photoxidation, Non-peptidic AVPI-mimics, Bicyclic γ-lactams, γ-hydroxybutenolides, 2-thiophenyl furans, (+)-yaoshanenolide B, Biomimetic synthesis, Diels-Alder reaction
وصف الملف: xiii, 213 σ. : πίν., σχήμ., εικ.; 30 εκ.
Relation: http://elocus.lib.uoc.gr:443/dlib/0/6/9/metadata-dlib-1487680916-567571-22333.tkl; 000406663
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15
المؤلفون: Oliver Nussbaumer, Hubert Gander, Juliana Komuczki, Georg Gruenbacher, Andrea Rahm, Martin Thurnher
المصدر: The Journal of Immunology. 191:1346-1355
مصطلحات موضوعية: Geranylgeranyl pyrophosphate, T-Lymphocytes, T cell, Immunology, Farnesyl pyrophosphate, Isopentenyl pyrophosphate, Biology, Lymphocyte Activation, Non-peptidic antigen, Zoledronic Acid, chemistry.chemical_compound, Immune system, Polyisoprenyl Phosphates, medicine, Humans, Immunology and Allergy, IL-2 receptor, Cells, Cultured, Chemokine CCL2, Cell Proliferation, Bone Density Conservation Agents, Diphosphonates, Caspase 1, Imidazoles, Interleukin-18, Interleukin-2 Receptor alpha Subunit, Receptors, Antigen, T-Cell, gamma-delta, Cell biology, medicine.anatomical_structure, chemistry, Leukocytes, Mononuclear, Protein prenylation
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16
المؤلفون: Singhal, Amit, Mori, Lucia, De Libero, Gennaro
المصدر: The Indian Journal of Medical Research
مصطلحات موضوعية: non-peptidic antigens, Antigen Presentation, Riboflavin, T-Lymphocytes, Receptors, Antigen, T-Cell, T cell, Antigen-Presenting Cells, Review Article, Microbial infection, Communicable Diseases, Major Histocompatibility Complex, TCR repertoire, peptidic antigens, Humans, T cell receptor, Antigens, Toll like receptors
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17
المؤلفون: Jorgensen, William
مصطلحات موضوعية: Oxytocin Receptor, Structure - Activity - Relationship, Agonist, Non-Peptidic
وصف الملف: application/pdf
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18
المؤلفون: José-Luis Giner, Yoshimasa Tanaka, Kia Joo Puan, Rong Cao, Craig T. Morita, Ju Feng, Jukka Mönkkönen, Ghanashyam Sarikonda, Eric Oldfield, Hong Wang
المصدر: The Journal of Immunology. 187:5099-5113
مصطلحات موضوعية: T cell, Immunology, Dose-Response Relationship, Immunologic, Isopentenyl pyrophosphate, Antigen-Presenting Cells, Mevalonic Acid, Stimulation, Biology, Lymphocyte Activation, Non-peptidic antigen, Article, chemistry.chemical_compound, Farnesyl diphosphate synthase, Prenylation, T-Lymphocyte Subsets, medicine, Humans, Immunology and Allergy, Cell Proliferation, Diphosphonates, Terpenes, Receptors, Antigen, T-Cell, gamma-delta, Transfection, Growth Inhibitors, Clone Cells, medicine.anatomical_structure, Biochemistry, chemistry, biology.protein, Mevalonate pathway, Signal Transduction
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19
المؤلفون: Manuela Mancini, Sara Petta, Valentina Corradi, Maurizio Botta, Maria Alessandra Santucci, Fabrizio Manetti
المساهمون: Corradi V., Mancini M., Manetti F., Petta S., Santucci M.A., Botta M.
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:6133-6137
مصطلحات موضوعية: Models, Molecular, IMATINIB RESISTANCE, 14-3-3 Proteins, Drug discovery, Leukemia, Molecular modeling, Non-peptidic compounds, Protein-protein interactions, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Apoptosis, Biochemistry, Piperazines, Small Molecule Libraries, Cell Line, Tumor, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, hemic and lymphatic diseases, Drug Discovery, medicine, Humans, Proto-Oncogene Proteins c-abl, neoplasms, Molecular Biology, CHRONIC MYELOID LEUKEMIA, ABL, Chemistry, Organic Chemistry, Imatinib, Ligand (biochemistry), medicine.disease, Small molecule, Protein Transport, Pyrimidines, Imatinib mesylate, Drug Resistance, Neoplasm, Benzamides, Imatinib Mesylate, Cancer research, DUAL SRC/ABL KINASE INHIBITORS, Molecular Medicine, Signal transduction, Protein Binding, medicine.drug
وصف الملف: STAMPA
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20
المؤلفون: Paolo Lupattelli, D. X. Kong, Adrian Ostric, Stanislav Miertus, Lucia Chiummiento, Vladimir Frecer, Maria Funicello, Carlo Bonini, N. Di Blasio, Federico Berti, Francesco Tramutola
المساهمون: Bonini, C, Chiummiento, L., Di Blasio, N., Funicello, M., Lupattelli, P., Tramutola, F., Berti, Federico, Ostric, Adrian, Miertus, S., Frecer, V., Kong, D. X.
مصطلحات موضوعية: Models, Molecular, Indoles, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Dose-Response Relationship, Structure-Activity Relationship, HIV PR inhibitors, Non-peptidic inhibitors, Dose-Response Relationship, Drug, HIV Protease, HIV Protease Inhibitors, Drug Discovery, medicine, HIV Protease Inhibitor, Peptide bond, Molecular Biology, Biological evaluation, Indole test, HIV PR inhibitor, Protease, Molecular Structure, Chemistry, Organic Chemistry, Regioselectivity, In vitro, Docking (molecular), Indole, Molecular Medicine, Non-peptidic inhibitor, Drug, Peptides
وصف الملف: STAMPA