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1Academic Journal
المؤلفون: Selvaraj, Muniyandi, Kokate, Shrikant B., Reggiano, Gabriella, Kogan, Konstantin, Kotila, Tommi, Kremneva, Elena, DiMaio, Frank, Lappalainen, Pekka, Huiskonen, Juha T.
المساهمون: Institute of Biotechnology, Pekka Lappalainen / Principal Investigator
مصطلحات موضوعية: actin, cofilin, CP: Cell biology, cryo-EM, cytoskeleton, non-muscle tropomyosin, Biochemistry, cell and molecular biology
وصف الملف: application/pdf
Relation: We thank Pasi Laurinmäki and Benita Löflund for technical assistance in cryo-EM. The facilities and expertise of the HiLIFE cryo-EM unit at the University of Helsinki, a member of Instruct-ERIC Center Finland, FINStruct, and Biocenter Finland are gratefully acknowledged. The authors wish to acknowledge CSC – IT Center for Science, Finland, for computational resources. This study was supported by grants from Academy of Finland (Center of Excellence grant 346133 to P.L.) and Sigrid Jusélius Foundation (4708344 to P.L.). Work in the laboratory of J.T.H. was supported by Helsinki Institute of Life Science HiLIFE. The graphical abstract was created with BioRender. Conceptualization, F.D. P.L. and J.T.H. Formal analysis, M.S. S.B.K. T.K. and J.T.H. Investigation, M.S. S.B.K. R.G. K.K. T.K. and K.E. Writing – original draft, S.B.K. P.L. and J.T.H. Writing – review & editing, M.S. S.B.K. P.L. and J.T.H. Visualization, J.T.H. Funding acquisition, P.L. Resources, S.B.K. E.K. and K.K. Supervision, F.D. P.L. and J.T.H. The authors declare no competing interests. We support inclusive, diverse, and equitable conduct of research. We thank Pasi Laurinmäki and Benita Löflund for technical assistance in cryo-EM. The facilities and expertise of the HiLIFE cryo-EM unit at the University of Helsinki, a member of Instruct-ERIC Center Finland, FINStruct, and Biocenter Finland are gratefully acknowledged. The authors wish to acknowledge CSC – IT Center for Science, Finland, for computational resources. This study was supported by grants from Academy of Finland (Center of Excellence grant 346133 to P.L.) and Sigrid Jusélius Foundation ( 4708344 to P.L.). Work in the laboratory of J.T.H. was supported by Helsinki Institute of Life Science HiLIFE . The graphical abstract was created with BioRender.; Selvaraj , M , Kokate , S B , Reggiano , G , Kogan , K , Kotila , T , Kremneva , E , DiMaio , F , Lappalainen , P & Huiskonen , J T 2023 , ' Structural basis underlying specific biochemical activities of non-muscle tropomyosin isoforms ' , Cell Reports , vol. 42 , no. 1 , 111900 . https://doi.org/10.1016/j.celrep.2022.111900; ORCID: /0000-0003-3270-9391/work/130604594; ORCID: /0000-0002-6274-537X/work/130605704; ORCID: /0000-0002-9046-5834/work/130605925; ORCID: /0000-0002-0348-7323/work/156150870; http://hdl.handle.net/10138/355850; 6433d723-6549-4aee-8c82-67afc4647903; 85147301422; 000965916900001
الاتاحة: http://hdl.handle.net/10138/355850
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المؤلفون: Muniyandi Selvaraj, Shrikant B. Kokate, Gabriella Reggiano, Konstantin Kogan, Tommi Kotila, Elena Kremneva, Frank DiMaio, Pekka Lappalainen, Juha T. Huiskonen
المساهمون: Institute of Biotechnology, Pekka Lappalainen / Principal Investigator
مصطلحات موضوعية: non-muscle tropomyosin, CP: Cell biology, cryo-EM, 1182 Biochemistry, cell and molecular biology, cytoskeleton, cofilin, actin, General Biochemistry, Genetics and Molecular Biology