المؤلفون: Isamu Shiina, Kenya Nakata, Yoshiyuki Sano

المصدر: Molecules, Vol 15, Iss 10, Pp 6773-6794 (2010)

مصطلحات موضوعية: three-component coupling reaction, diversity oriented synthesis, lasofoxifene, nafoxidine, inv-lasofoxifene, inv-nafoxidine, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/15/10/6773/; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/c50f8931d27647b0911ee7934c0723a7

المؤلفون: Jonathan G. L. Mullins, Karl Austin-Muttitt, Shiyan Chen, Linghua Harris Zhang, Aik Jiang Lau

المصدر: Journal of Pharmacology and Experimental Therapeutics. 371:75-86

مصطلحات موضوعية: Male, Selective Estrogen Receptor Modulators, 0301 basic medicine, Indoles, Pyrrolidines, Tetrahydronaphthalenes, Pharmacology, Acolbifene, Bazedoxifene, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Humans, Aldehyde oxidase, Binding Sites, Lasofoxifene, Aldehyde Oxidase, Molecular Docking Simulation, 030104 developmental biology, Liver, chemistry, Selective estrogen receptor modulator, Docking (molecular), Molecular Medicine, Female, Aldehyde oxidase 1, Nafoxidine, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395f34d59c0bad1e3a3940b3948c1c3d
https://doi.org/10.1124/jpet.119.259267

المؤلفون: Sumit Bansal, Aik Jiang Lau

المصدر: Journal of Pharmacology and Experimental Therapeutics. 369:389-405

مصطلحات موضوعية: Selective Estrogen Receptor Modulators, 0301 basic medicine, Sulfotransferase, Lithocholic acid, genetic structures, Pharmacology, Acolbifene, Bazedoxifene, 03 medical and health sciences, chemistry.chemical_compound, Cytosol, 0302 clinical medicine, parasitic diseases, medicine, Humans, Toremifene, Chemistry, Lasofoxifene, Hep G2 Cells, eye diseases, Kinetics, 030104 developmental biology, Liver, Selective estrogen receptor modulator, Biocatalysis, Molecular Medicine, Lithocholic Acid, sense organs, Sulfonic Acids, Sulfotransferases, Nafoxidine, Oxidation-Reduction, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery, Taurolithocholic Acid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fdbf31a73aabcf84f3b45fec515432
https://doi.org/10.1124/jpet.119.256255

المؤلفون: Clark, James H., Hardin, James W., Padykula, Helen A., Cardasis, Constance A.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 1978 Jun 01. 75(6), 2781-2784.

URL الوصول: https://www.jstor.org/stable/68327

المؤلفون: Zdenko Časar, Carin C. C. Johansson Seechurn, Antonio Zanotti-Gerosa, Thomas J. Colacot, Ivana Gazic Smilovic

المصدر: Bioorganic & Medicinal Chemistry. 26:2691-2697

مصطلحات موضوعية: Nafoxidine, Clinical Biochemistry, Pharmaceutical Science, chemistry.chemical_element, 010402 general chemistry, 01 natural sciences, Biochemistry, Catalysis, chemistry.chemical_compound, Coordination Complexes, Drug Discovery, Tetralone, medicine, Molecular Biology, 010405 organic chemistry, Organic Chemistry, Lasofoxifene, Combinatorial chemistry, 0104 chemical sciences, chemistry, Chlorobenzene, Yield (chemistry), Alkoxy group, Molecular Medicine, Palladium, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9d563cdaeb4a1196b2d7de950eee2c
https://doi.org/10.1016/j.bmc.2018.04.021

المؤلفون: Samar Lahmar, Kaouthar Kessabi, Mohamed Banni, Imed Messaoudi

المصدر: Fish physiology and biochemistry. 46(2)

مصطلحات موضوعية: medicine.medical_specialty, Physiology, medicine.drug_class, Estrogen receptor, Aquatic Science, Biochemistry, Bone and Bones, Estrogen Receptor Antagonists, Bone remodeling, Melatonin, 03 medical and health sciences, Cyprinodontiformes, Internal medicine, medicine, Animals, Killifish, 030304 developmental biology, 0303 health sciences, biology, 04 agricultural and veterinary sciences, General Medicine, biology.organism_classification, Spinal column, Endocrinology, Liver, Estrogen, Dietary Supplements, 040102 fisheries, 0401 agriculture, forestry, and fisheries, Nafoxidine Hydrochloride, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96af1ad22b5b80d9301874219339e97a
https://pubmed.ncbi.nlm.nih.gov/31853706

المؤلفون: Pailla Umareddy, Veera Reddy Arava

المصدر: Synthetic Communications. 46:309-313

مصطلحات موضوعية: Diketone, 010405 organic chemistry, Organic Chemistry, Total synthesis, Lasofoxifene, 010402 general chemistry, 01 natural sciences, Medicinal chemistry, 0104 chemical sciences, Benzaldehyde, chemistry.chemical_compound, chemistry, Intramolecular force, medicine, Organic chemistry, Nafoxidine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd1cdfbecadff6872f3d713e5fa7e400
https://doi.org/10.1080/00397911.2015.1135957

المؤلفون: Enrico Marelli, José A. Fernández Salas, Steven P. Nolan

المصدر: Synthesis. 47:2032-2037

مصطلحات موضوعية: inorganic chemicals, Reaction conditions, chemistry.chemical_classification, Ketone, Organic Chemistry, Substrate (chemistry), chemistry.chemical_element, Catalysis, Coupling reaction, Nickel, chemistry, medicine, Organic chemistry, Nafoxidine, medicine.drug, Palladium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e7f8a330dfc753b1b7e4d7b6071b40e8
https://doi.org/10.1055/s-0034-1380813

المؤلفون: Yoshiyuki Sano, Isamu Shiina, Kenya Nakata

المصدر: Molecules
Molecules, Vol 15, Iss 10, Pp 6773-6794 (2010)
Volume 15
Issue 10
Pages 6773-6794

مصطلحات موضوعية: Stereochemistry, Pharmaceutical Science, diversity oriented synthesis, Coupling reaction, Article, three-component coupling reaction, Analytical Chemistry, lcsh:QD241-441, chemistry.chemical_compound, lcsh:Organic chemistry, lasofoxifene, Drug Discovery, Structural isomer, medicine, inv-nafoxidine, Physical and Theoretical Chemistry, inv-lasofoxifene, Olefin fiber, Chemistry, Organic Chemistry, Lasofoxifene, Anisole, nafoxidine, Chemistry (miscellaneous), Yield (chemistry), Molecular Medicine, Hydrogen iodide, Nafoxidine, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08009d24f3c58ce0e32f935b92b67cdd
http://europepmc.org/articles/PMC6259163

المؤلفون: Lirit N. Franks, Benjamin M. Ford, Paul L. Prather

المصدر: Frontiers in Pharmacology

مصطلحات موضوعية: 0301 basic medicine, Agonist, medicine.medical_specialty, medicine.drug_class, medicine.medical_treatment, Estrogen receptor, Pharmacology, inverse agonist, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Cannabinoid receptor type 2, Inverse agonist, Pharmacology (medical), Original Research, Chemistry, antagonist, cannabinoid, CB1, drug development, SERM, CB2, 030104 developmental biology, Endocrinology, Selective estrogen receptor modulator, G-protein coupled receptor, Cannabinoid, Nafoxidine, 030217 neurology & neurosurgery, Tamoxifen, hormones, hormone substitutes, and hormone antagonists, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0dfb805707b2263d838195adb9af32f

المؤلفون: Pinar Öztopcu, Ramazan Durmaz, Ruhi Uyar, Gökcen Yaz, Selda Kabadere

المصدر: American Journal of Clinical Oncology. 27:384-388

مصطلحات موضوعية: Cancer Research, Antineoplastic Agents, Hormonal, Nafoxidine, Combination therapy, Cell Survival, Metabolite, Pharmacology, Clomiphene, chemistry.chemical_compound, Cell Line, Tumor, Glioma, Animals, Humans, Medicine, Potency, IC50, Tumor Stem Cell Assay, Dose-Response Relationship, Drug, business.industry, Estrogen Antagonists, medicine.disease, In vitro, Rats, Tamoxifen, Oncology, chemistry, business, Cell Division, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06776a81e9646b0cf120196603ab9f73
https://doi.org/10.1097/01.coc.0000071945.15623.c6

المؤلفون: Sherin Varghese, Dinu Dixon, Camelia Maier, Paramita Basu

المصدر: Pharmacognosy Research. 10:137

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, biology, medicine.drug_class, Estrogen receptor, Catechin, biology.organism_classification, Blowing a raspberry, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, Black raspberry, Estrogen, 030220 oncology & carcinogenesis, Drug Discovery, medicine, Nafoxidine, Quercetin, Estrogen receptor alpha, hormones, hormone substitutes, and hormone antagonists, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d3b92f25e7b2163af80871c2a4cd5e8c
https://doi.org/10.4103/pr.pr_111_17

المؤلفون: Dan Lednicer

المصدر: Current Medicinal Chemistry. 9:1457-1461

مصطلحات موضوعية: Pharmacology, Biochemistry, Lactones, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Humans, Cyclooxygenase Inhibitors, Sulfones, Rofecoxib, Indole test, Sulfonamides, Cyclooxygenase 2 Inhibitors, Estradiol, biology, Chemistry, Anti-Inflammatory Agents, Non-Steroidal, Organic Chemistry, Estrogen Antagonists, Membrane Proteins, Biological activity, History, 20th Century, Isoenzymes, Celecoxib, Cyclooxygenase 2, Prostaglandin-Endoperoxide Synthases, Enzyme inhibitor, Drug Design, biology.protein, Pyrazoles, Molecular Medicine, Cyclooxygenase, Nafoxidine, Tamoxifen, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f18d2a727c5183cce010646647e67d
https://doi.org/10.2174/0929867023369727

المؤلفون: Peter K. LeMotte, Samuel P. Simons, Kieran F. Geoghegan, Preston Hensley, Rebecca L. Rich, David G. Myszka, Lise R. Hoth, Thomas A. Brown

المصدر: Proceedings of the National Academy of Sciences. 99:8562-8567

مصطلحات موضوعية: Multidisciplinary, Chemistry, Ligand, Estrogen Receptor alpha, Antibodies, Monoclonal, Estrogen receptor, Dehydroepiandrosterone, Biological Sciences, Ligands, Small molecule, Recombinant Proteins, Protein–protein interaction, Kinetics, Phenols, Receptors, Estrogen, Biochemistry, medicine, Estrogen Receptor beta, Benzhydryl Compounds, Nafoxidine, Receptor, Estrogen receptor alpha, Estrogen receptor beta, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcc5dac20f1334997435c623de0af57f
https://doi.org/10.1073/pnas.142288199

المؤلفون: Guy R. Seabrook, Zahid Moneer, Anthony J. Woollacott, Peter B. Simpson, Vikki Rand

المصدر: NeuroReport. 13:957-960

مصطلحات موضوعية: Selective Estrogen Receptor Modulators, medicine.medical_specialty, SH-SY5Y, medicine.drug_class, Estrogen receptor, Biology, Pharmacology, Mitochondrion, Ligands, Permeability, Membrane Potentials, Neuroblastoma, chemistry.chemical_compound, Cyclosporin a, Internal medicine, Tumor Cells, Cultured, polycyclic compounds, medicine, Humans, Enzyme Inhibitors, Dose-Response Relationship, Drug, General Neuroscience, Intracellular Membranes, Mitochondria, Calcein, Endocrinology, Receptors, Estrogen, chemistry, Estrogen, Mastoparan, Cyclosporine, Nafoxidine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9652721581a4f83f22a2862b37e37c
https://doi.org/10.1097/00001756-200205240-00011

المؤلفون: Fadeke A. Agboke, Russell E. McDaniel, Philipp Y. Maximov, V. Craig Jordan

المصدر: Steroids. 90

مصطلحات موضوعية: Oncology, Selective Estrogen Receptor Modulators, medicine.medical_specialty, medicine.biofluid, Clinical Biochemistry, Estrogen receptor, Breast Neoplasms, Pharmacology, Biochemistry, Article, Endocrinology, Breast cancer, Estrogen Receptor Modulators, Internal medicine, medicine, Animals, Humans, skin and connective tissue diseases, Molecular Biology, business.industry, Vaginal lubrication, Organic Chemistry, Antiestrogen, medicine.disease, Endometrial Neoplasms, Tamoxifen, Selective estrogen receptor modulator, Female, Nafoxidine, business, Ethamoxytriphetol, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4cf21fcc8dde7d769f52a31668f2fd
https://pubmed.ncbi.nlm.nih.gov/24949934

المؤلفون: Ali Yazdanyar, Michael Essmann, Bryan Larsen

المصدر: Journal of Biomedical Science. 8:153-159

مصطلحات موضوعية: Nafoxidine, medicine.drug_class, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Virulence, Genistein, Biology, Microbiology, chemistry.chemical_compound, Nephelometry and Turbidimetry, Candida albicans, medicine, Humans, Pharmacology (medical), HSP90 Heat-Shock Proteins, Molecular Biology, Dose-Response Relationship, Drug, Estradiol, Cell Cycle, Biochemistry (medical), Candidiasis, Estrogen Antagonists, Cell Biology, General Medicine, Protein-Tyrosine Kinases, Cell cycle, biology.organism_classification, chemistry, Estrogen, Female, Cell Division, Signal Transduction, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5143b6853ba08f9d66df288a7183c32
https://doi.org/10.1007/bf02256407

المؤلفون: Guillaume Droogmans, P Chakraborty, Chantal Maertens, Bernd Nilius

المصدر: British Journal of Pharmacology. 132:135-142

مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Endothelium, Chemistry, Zuclomiphene, In vitro, Endocrinology, medicine.anatomical_structure, Mechanism of action, Clomifene, Internal medicine, medicine, Chloride channel, Patch clamp, medicine.symptom, Nafoxidine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c58ea5a77f1cf1ad33a17748091d5dc0
https://doi.org/10.1038/sj.bjp.0703786

المؤلفون: John A. Katzenellenbogen, Sung Hoon Kim

المصدر: Bioorganic & Medicinal Chemistry. 8:785-793

مصطلحات موضوعية: Models, Molecular, Magnetic Resonance Spectroscopy, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Estrogen receptor, Spectrometry, Mass, Fast Atom Bombardment, Ligands, Biochemistry, chemistry.chemical_compound, Phenols, Drug Discovery, medicine, Molecular Biology, chemistry.chemical_classification, Alkene, Aryl, Organic Chemistry, Sodium naphthalenide, Ethylenes, Ligand (biochemistry), Antiestrogen, Receptors, Estrogen, chemistry, Molecular Medicine, Nafoxidine, Estrogen receptor alpha, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb5339068c055c1644acf5bbefa0676
https://doi.org/10.1016/s0968-0896(00)00016-x

المؤلفون: A. F. Stewart, Mark Nichols, Colin Logie, J. M. J. Rientjes

المصدر: Molecular Endocrinology. 11:950-961

مصطلحات موضوعية: Hexestrol, Time Factors, Nafoxidine, Recombinant Fusion Proteins, Molecular Sequence Data, Estrogen receptor, Biology, Ligands, Endocrinology, Piperidines, Yeasts, Recombinase, Humans, Amino Acid Sequence, Estrogens, Non-Steroidal, HSP90 Heat-Shock Proteins, Diethylstilbestrol, Fulvestrant, Molecular Biology, Protease-activated receptor 2, Estrogen receptor beta, Dose-Response Relationship, Drug, Estradiol, Estrogen Antagonists, General Medicine, Ligand (biochemistry), Fusion protein, Tamoxifen, Receptors, Estrogen, Biochemistry, Raloxifene Hydrochloride, DNA Nucleotidyltransferases, Estrogen-related receptor gamma, Estrogen receptor alpha, Bacterial Outer Membrane Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ddac8d99c363d3c9f0a1e4fdfedb9d1
https://doi.org/10.1210/mend.11.7.9944