المؤلفون: Dániel Sztankovics, Fatime Szalai, Dorottya Moldvai, Titanilla Dankó, Noémi Nagy, Judit Pápay, András Khoór, Ildikó Krencz, Anna Sebestyén

المصدر: European Journal of Cell Biology, Vol 103, Iss 4, Pp 151468- (2024)

مصطلحات موضوعية: Small cell lung carcinoma, RICTOR amplification, mTOR hyperactivity, mTORC2, Tumour progression, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0171933524000852; https://doaj.org/toc/0171-9335

URL الوصول: https://doaj.org/article/330b1db415774fd19967c36c4c2a7cae

المؤلفون: Jordan, Justin, Orr, Christina, Thalheimer, Raquel, Cambillo, Josephine, Beauchamp, Roberta, Shaikh, Ghalib, Muzikansky, Alona, Stemmer-Rachamimov, Anat, Giovannini, Marco, Kalamarides, Michel, Barker, Fred, Ramesh, Vijaya, Plotkin, Scott

المصدر: NOA. 5(1)

مصطلحات موضوعية: NF2, mTOR, mTORC1, mTORC2, meningioma, neurofibromatosis 2, vistusertib

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7c73p1v7
https://escholarship.org/content/qt7c73p1v7/qt7c73p1v7.pdf

المؤلفون: Luca Ponzone, Valentina Audrito, Claudia Landi, Enrico Moiso, Chiara Levra Levron, Sara Ferrua, Aurora Savino, Nicoletta Vitale, Massimiliano Gasparrini, Lidia Avalle, Lorenza Vantaggiato, Enxhi Shaba, Beatrice Tassone, Stefania Saoncella, Francesca Orso, Daniele Viavattene, Eleonora Marina, Irene Fiorilla, Giulia Burrone, Youssef Abili, Fiorella Altruda, Luca Bini, Silvia Deaglio, Paola Defilippi, Alessio Menga, Valeria Poli, Paolo Ettore Porporato, Paolo Provero, Nadia Raffaelli, Chiara Riganti, Daniela Taverna, Federica Cavallo, Enzo Calautti

المصدر: Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)

مصطلحات موضوعية: mTORC2, RICTOR, NAMPT, Drug resistance, Targeted therapy, BRAFV600E melanoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1476-4598

URL الوصول: https://doaj.org/article/18874da7221f495c92ee85e23df7d535

المؤلفون: Mio Harachi, Kenta Masui, Erika Shimizu, Kumiko Murakami, Hiromi Onizuka, Yoshihiro Muragaki, Takakazu Kawamata, Hisako Nakayama, Mariko Miyata, Takashi Komori, Webster K. Cavenee, Paul S. Mischel, Atsushi Kurata, Noriyuki Shibata

المصدر: Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-17 (2024)

مصطلحات موضوعية: DNA hypomethylation, mTORC2, DNMT3A, EZH2, Glutamate metabolism, Glioblastoma, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-5960

URL الوصول: https://doaj.org/article/59ba976a12834ee782df85c5cc6333ba

المؤلفون: Yu, Zanlin, Chen, Junliang, Takagi, Enzo, Wang, Feng, Saha, Bidisha, Liu, Xi, Joubert, Lydia-Marie, Gleason, Catherine E, Jin, Mingliang, Li, Chengmin, Nowotny, Carlos, Agard, David, Cheng, Yifan, Pearce, David

المصدر: Journal of Biological Chemistry. 298(9)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Cardiovascular, Emerging Infectious Diseases, Underpinning research, 1.1 Normal biological development and functioning, Generic health relevance, Humans, Immediate-Early Proteins, Mechanistic Target of Rapamycin Complex 1, Monomeric GTP-Binding Proteins, Phosphorylation, Protein Serine-Threonine Kinases, Proto-Oncogene Proteins c-akt, Rapamycin-Insensitive Companion of mTOR Protein, Sirolimus, Transcription Factors, Akt, SGK1, conformation change, cryo-EM, mTORC2, structure, substrate specificity, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9589f51q

المؤلفون: Peter C. Breen, Kendall G. Kanakanui, Martin A. Newman, Robert H. Dowen

المصدر: Frontiers in Cell and Developmental Biology, Vol 12 (2024)

مصطلحات موضوعية: development, vitellogenesis, f-box, mTORC2, rict-1, lipid, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2024.1389077/full; https://doaj.org/toc/2296-634X

URL الوصول: https://doaj.org/article/41758bc7c01f4177b709baa5c955213d

المؤلفون: Mario Palma, Elizabeth Riffo, Alejandro Farias, Viviana Coliboro-Dannich, Luis Espinoza-Francine, Emilia Escalona, Roberto Amigo, José L. Gutiérrez, Roxana Pincheira, Ariel F. Castro

المصدر: Cell & Bioscience, Vol 13, Iss 1, Pp 1-22 (2023)

مصطلحات موضوعية: Akt, Cancer signaling, Co-targeting, mTORC2, NUAK1, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-3701

URL الوصول: https://doaj.org/article/b147c3f3e6e94b8ca50919e790866969

المؤلفون: Kosillo, Polina, Ahmed, Kamran M, Aisenberg, Erin E, Karalis, Vasiliki, Roberts, Bradley M, Cragg, Stephanie J, Bateup, Helen S

مصطلحات موضوعية: Neurosciences, Underpinning research, 1.1 Normal biological development and functioning, Animals, Dopamine, Dopaminergic Neurons, Mechanistic Target of Rapamycin Complex 1, Mechanistic Target of Rapamycin Complex 2, Mice, TOR Serine-Threonine Kinases, mTORC1, mTORC2, raptor, rictor, dopamine neurons, TSC, Mouse, mouse, neuroscience, Biochemistry and Cell Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/47p0s09p

المؤلفون: Pundrik Jaiswal, Netra Pal Meena, Fu-Sheng Chang, Xin-Hua Liao, Lou Kim, Alan R. Kimmel

مصطلحات موضوعية: Cell Biology, Marine Biology, Cell Development, Proliferation and Death, Cell Metabolism, Cell Neurochemistry, Cellular Interactions (incl. Adhesion, Matrix, Cell Wall), receptors, adenylate cyclases, protein kinases, protein phosphatases, phosphodiesterases, G proteins, ras, mTORC2

Relation: https://figshare.com/articles/presentation/Presentation1_An_integrated_cross-regulation_pathway_model_involving_activating_adaptive_and_feed-forward_feed-back_loops_for_directed_oscillatory_cAMP_signal-relay_response_during_the_development_of_Dictyostelium_zip/25117907

الاتاحة: https://doi.org/10.3389/fcell.2023.1263316.s002
https://figshare.com/articles/presentation/Presentation1_An_integrated_cross-regulation_pathway_model_involving_activating_adaptive_and_feed-forward_feed-back_loops_for_directed_oscillatory_cAMP_signal-relay_response_during_the_development_of_Dictyostelium_zip/25117907

المؤلفون: Ildikó Krencz, Dániel Sztankovics, Anna Sebestyén, Judit Pápay, Titanilla Dankó, Dorottya Moldvai, Elmar Lutz, Andras Khoor

المصدر: Pathology and Oncology Research, Vol 30 (2024)

مصطلحات موضوعية: RICTOR amplification, Rictor expression, mTORC2, PD-L1, lung squamous cell carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Pathology, RB1-214

وصف الملف: electronic resource

Relation: https://www.por-journal.com/articles/10.3389/pore.2024.1611593/full; https://doaj.org/toc/1532-2807

URL الوصول: https://doaj.org/article/fc3d684fdaff4c96b26aca54c6f8cf21

المؤلفون: Ha Eun Kim, Jong Yeong Lee, Dong-Hoon Yoo, Hyo-Hyun Park, Eun-Ju Choi, Kyung-Hwa Nam, Jin Park, Jin Kyeong Choi

المصدر: Frontiers in Immunology, Vol 15 (2024)

مصطلحات موضوعية: imidazole propionate, atopic dermatitis, mitochondria ROS, mTORC2, AMPK, DDIT4, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1324026/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/bf83a1785bcb409aafdb7afd46ee1cb6

المؤلفون: Dániel Sztankovics, Dorottya Moldvai, Gábor Petővári, Titanilla Dankó, Fatime Szalai, Risa Miyaura, Viktória Varga, Noémi Nagy, Gergő Papp, Judit Pápay, Ildikó Krencz, Anna Sebestyén

المصدر: Pathology and Oncology Research, Vol 30 (2024)

مصطلحات موضوعية: mTOR, mTORC2 hyperactivity, RICTOR amplification, Rictor overexpression, malignancies, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Pathology, RB1-214

وصف الملف: electronic resource

Relation: https://www.por-journal.com/articles/10.3389/pore.2024.1611643/full; https://doaj.org/toc/1532-2807

URL الوصول: https://doaj.org/article/50d1c7653f534df2bad19730c717af5b

المؤلفون: Holmes, Brent, Benavides-Serrato, Angelica, Saunders, Jacquelyn T, Kumar, Sunil, Nishimura, Robert N, Gera, Joseph

المصدر: Neoplasia. 23(9)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Cancer, Brain Cancer, Neurosciences, Brain Disorders, Genetics, Rare Diseases, 2.1 Biological and endogenous factors, Animals, Brain Neoplasms, Cell Line, Tumor, Female, Glioblastoma, Hippo Signaling Pathway, Humans, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, SCID, Neoplasm Invasiveness, Phosphorylation, Tumor Burden, Xenograft Model Antitumor Assays, YAP-Signaling Proteins, mTORC2, YAP, Signal transduction, Oncology & Carcinogenesis, Clinical sciences, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4x57n04t
https://escholarship.org/content/qt4x57n04t/qt4x57n04t.pdf

المؤلفون: Castel, Pau, Dharmaiah, Srisathiyanarayanan, Sale, Matthew J, Messing, Simon, Rizzuto, Gabrielle, Cuevas-Navarro, Antonio, Cheng, Alice, Trnka, Michael J, Urisman, Anatoly, Esposito, Dominic, Simanshu, Dhirendra K, McCormick, Frank

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 118(33)

مصطلحات موضوعية: Humans, Adaptor Proteins, Signal Transducing, Protein Isoforms, Signal Transduction, Gene Expression Regulation, Protein Conformation, Models, Molecular, Proto-Oncogene Proteins p21(ras), Mass Spectrometry, HEK293 Cells, Mechanistic Target of Rapamycin Complex 2, KRAS, RAS, RBD, Sin1, mTORC2, 2.1 Biological and endogenous factors, Aetiology, Cancer

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5tt979r3

المؤلفون: Miguel Enrique Cuéllar Mendoza, Francisco Raúl Chávez Sánchez, Elisa María Dorantes Acosta, Ana María Niembro Zúñiga, Rosana Pelayo, Marta Zapata Tarrés

المصدر: Frontiers in Oncology, Vol 14 (2024)

مصطلحات موضوعية: mTOR, acute lymphoblastic leukemia, Hodgkin lymphoma, mTORC1, mTORC2, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1304605/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/f0ab00f048ec4926b95de3fe85636312

المؤلفون: Kartini Iskandar, Jonathan Foo, Angeline Qiu Xia Liew, Haiyuxin Zhu, Deepika Raman, Jayshree L. Hirpara, Yan Yi Leong, Maria V. Babak, Anna A. Kirsanova, Anne-Sophie Armand, Franck Oury, Gregory Bellot, Shazib Pervaiz

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Physiology, Pharmacology, Developmental Biology, Cancer, Hematology, Infectious Diseases, Chemical Sciences not elsewhere classified, AKT, DNM1L, KRAS, mitofission, MTORC2, ROS

Relation: https://figshare.com/articles/journal_contribution/A_NOVEL_MTORC2-AKT-ROS_AXIS_TRIGGERS_MITOFISSION_and_MITOPHAGY-ASSOCIATED_EXECUTION_of_COLORECTAL_CANCER_CELLS_UPON_DRUG-INDUCED_ACTIVATION_of_MUTANT_KRAS/25050075

الاتاحة: https://doi.org/10.6084/m9.figshare.25050075.v2
https://figshare.com/articles/journal_contribution/A_NOVEL_MTORC2-AKT-ROS_AXIS_TRIGGERS_MITOFISSION_and_MITOPHAGY-ASSOCIATED_EXECUTION_of_COLORECTAL_CANCER_CELLS_UPON_DRUG-INDUCED_ACTIVATION_of_MUTANT_KRAS/25050075

المؤلفون: Luciano, Amelia K, Korobkina, Ekaterina D, Lyons, Scott P, Haley, John A, Fluharty, Shelagh M, Jung, Su Myung, Kettenbach, Arminja N, Guertin, David A

المساهمون: Molecular, Cell and Cancer Biology, Morningside Graduate School of Biomedical Sciences, Program in Molecular Medicine, Ekaterina D Korobkina, John A Haley

المصدر: The Journal of biological chemistry ; 298 ; 10 ; 102379 ; United States

مصطلحات موضوعية: ADP ribosylation factor, Akt/PKB, BioID2, RICTOR, cell signaling, growth factor, mTORC2, mammalian target of rapamycin, proximity labeling

Relation: Journal of Biological Chemistry; https://doi.org/10.1016/j.jbc.2022.102379; Luciano AK, Korobkina ED, Lyons SP, Haley JA, Fluharty SM, Jung SM, Kettenbach AN, Guertin DA. Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1. J Biol Chem. 2022 Oct;298(10):102379. doi:10.1016/j.jbc.2022.102379. Epub 2022 Aug 13. PMID: 35973513; PMCID: PMC9513271.; http://hdl.handle.net/20.500.14038/52938; The Journal of biological chemistry

الاتاحة: https://doi.org/10.1016/j.jbc.2022.102379
https://hdl.handle.net/20.500.14038/52938

المؤلفون: Fatime Szalai, Dániel Sztankovics, Ildikó Krencz, Dorottya Moldvai, Judit Pápay, Anna Sebestyén, Andras Khoor

المصدر: Cancers, Vol 16, Iss 3, p 543 (2024)

مصطلحات موضوعية: lung cancer, mTOR pathway, mTORC2, RICTOR amplification, Rictor overexpression, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: https://www.mdpi.com/2072-6694/16/3/543; https://doaj.org/toc/2072-6694; https://doaj.org/article/bfb0786c88374b7986c9b3f846df4d1c

الاتاحة: https://doi.org/10.3390/cancers16030543
https://doaj.org/article/bfb0786c88374b7986c9b3f846df4d1c

المؤلفون: Meena Jhanwar-Uniyal, Sabrina L. Zeller, Eris Spirollari, Mohan Das, Simon J. Hanft, Chirag D. Gandhi

المصدر: Cells, Vol 13, Iss 5, p 409 (2024)

مصطلحات موضوعية: mTOR, mTORC1, mTORC2, S6K, 4E-BP1, GBM, Cytology, QH573-671

Relation: https://www.mdpi.com/2073-4409/13/5/409; https://doaj.org/toc/2073-4409; https://doaj.org/article/07462b5f042c406781170e1feda5e21f

الاتاحة: https://doi.org/10.3390/cells13050409
https://doaj.org/article/07462b5f042c406781170e1feda5e21f

المؤلفون: Elisabet Ampudia-Mesias, Charles S. Cameron, Eunjae Yoo, Marcus Kelly, Sarah M. Anderson, Riley Manning, Juan E. Abrahante Lloréns, Christopher L. Moertel, Hyungshin Yim, David J. Odde, Nurten Saydam, Okay Saydam

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 8, p 4416 (2024)

مصطلحات موضوعية: OTX2, mTORC2, LMD, group 3 medulloblastoma, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/8/4416; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/904ab838c5e0474c8f15d4089df2085b

الاتاحة: https://doi.org/10.3390/ijms25084416
https://doaj.org/article/904ab838c5e0474c8f15d4089df2085b