المؤلفون: Masaru Miyagi (229956), Kohei Tanaka (831041), Shinko Watanabe (11649278), Jun Kondo (548450), Taro Kishimoto (6924317)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Molecular Biology, Pharmacology, Biotechnology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, hydrogen deuterium exchange, hek293 cell lysates, endogenously expressed mapk14, chemical moieties used, protein stability induced, lc – ms, require covalent modifications, drugs may mask, critical recognition site, 2 , method uses histidine, capturing interacting proteins, methods identify targets, covalent modifications, protein denaturant, ms ), interacting proteins, various concentrations, successfully applied, solid support

Relation: https://figshare.com/articles/journal_contribution/Identifying_Protein_Drug_Interactions_in_Cell_Lysates_Using_Histidine_Hydrogen_Deuterium_Exchange/16934066

الاتاحة: https://doi.org/10.1021/acs.analchem.1c02283.s001

المؤلفون: Masaru Miyagi (229956), Kohei Tanaka (831041), Shinko Watanabe (11649278), Jun Kondo (548450), Taro Kishimoto (6924317)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Molecular Biology, Pharmacology, Biotechnology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, hydrogen deuterium exchange, hek293 cell lysates, endogenously expressed mapk14, chemical moieties used, protein stability induced, lc – ms, require covalent modifications, drugs may mask, critical recognition site, 2 , method uses histidine, capturing interacting proteins, methods identify targets, covalent modifications, protein denaturant, ms ), interacting proteins, various concentrations, successfully applied, solid support

Relation: https://figshare.com/articles/dataset/Identifying_Protein_Drug_Interactions_in_Cell_Lysates_Using_Histidine_Hydrogen_Deuterium_Exchange/16934069

الاتاحة: https://doi.org/10.1021/acs.analchem.1c02283.s002