المؤلفون: Silvia Cases-Cunillera, Karen M J van Loo, Julika Pitsch, Anne Quatraccioni, Sugirthan Sivalingam, Paolo Salomoni, Valeri Borger, Dirk Dietrich, Susanne Schoch, Albert J Becker

المصدر: Neuro-Oncology 24(5), 741-754 (2022). doi:10.1093/neuonc/noab268

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, Cancer Research, MTOR protein, human, genetics [Proto-Oncogene Proteins B-raf], metabolism [TOR Serine-Threonine Kinases], epileptogenicity, Mice, metabolism [Proto-Oncogene Proteins B-raf], physiology [Signal Transduction], Animals, Humans, ddc:610, pediatric tumor, Ganglioglioma, dysplastic neuron, Brain Neoplasms, TOR Serine-Threonine Kinases, genetics [TOR Serine-Threonine Kinases], metabolism [Brain Neoplasms], genetics [Brain Neoplasms], Oncology, Mutation, metabolism [Proto-Oncogene Proteins c-akt], genetics [Ganglioglioma], genetics [Proto-Oncogene Proteins c-akt], Neurology (clinical), neoplastic astroglia, Proto-Oncogene Proteins c-akt, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c084401789e468e8a20d91d828e5463a

المؤلفون: Lamya Yamani, Frances R. Balkwill, Federica M. Marelli-Berg, Juho Vuononvirta, Melania Capasso, Eleanor J. Ward, Suchita Nadkarni, Maryam Jangani

المصدر: Journal of leukocyte biology 111(5), 967-980 (2022). doi:10.1002/JLB.1A0920-588R

مصطلحات موضوعية: Immunology, Inflammation, Mechanistic Target of Rapamycin Complex 2, macrophage, Biology, mTORC2, Monocytes, Proinflammatory cytokine, cell metabolism, ddc:570, medicine, Immunology and Allergy, Macrophage, Protein kinase B, Mechanistic target of rapamycin, Sirolimus, Monocyte, Macrophages, Cell Biology, Cell biology, metabolism [Rapamycin-Insensitive Companion of mTOR Protein], medicine.anatomical_structure, Rapamycin-Insensitive Companion of mTOR Protein, metabolism [Proto-Oncogene Proteins c-akt], monocyte, biology.protein, Phosphorylation, metabolism [Macrophages], metabolism [Mechanistic Target of Rapamycin Complex 2], medicine.symptom, Proto-Oncogene Proteins c-akt, metabolism, metabolism [Monocytes]

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c37bac8cd8d674c7b85b94c49a2a57
https://pub.dzne.de/record/162927

المؤلفون: Wolfgang Wurst, Thomas Ott, Kathrin Brockmann, Daniela Vogt-Weisenhorn, Andrea Wenninger-Weinzierl, Marita Munz, Ralf Kühn, Saskia Biskup, Florian Giesert, Natalja Funk, Thomas Gasser

المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific reports 9(1), 4515 (2019). doi:10.1038/s41598-019-40808-y
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, drug effects [Neuronal Outgrowth], metabolism [Leucine-Rich Repeat Serine-Threonine Protein Kinase-2], lcsh:Medicine, pharmacology [Fibroblast Growth Factors], Mice, 0302 clinical medicine, cytology [Fibroblasts], Insulin, Phosphorylation, lcsh:Science, pharmacology [Insulin], Glucose Transporter Type 4, Multidisciplinary, Kinase, Parkinson Disease, LRRK2, metabolism [rab GTP-Binding Proteins], Cell biology, ddc, Intracellular signal transduction, metabolism [Proto-Oncogene Proteins c-akt], Signal transduction, Technology Platforms, metabolism [Fibroblasts], Signal Transduction, drug effects [Signal Transduction], Cell Survival, drug effects [Cell Survival], Neuronal Outgrowth, metabolism [Parkinson Disease], Biology, Leucine-rich repeat, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Polymorphism, Single Nucleotide, Article, 03 medical and health sciences, Animals, Humans, Protein kinase B, lcsh:R, Fibroblasts, metabolism [Glucose Transporter Type 4], pathology [Parkinson Disease], Rats, nervous system diseases, Fibroblast Growth Factors, 030104 developmental biology, rab GTP-Binding Proteins, biology.protein, genetics [Leucine-Rich Repeat Serine-Threonine Protein Kinase-2], lcsh:Q, Proto-Oncogene Proteins c-akt, ddc:600, 030217 neurology & neurosurgery, GLUT4

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9ccd730fe7023ec1eb8e959bc4ec6f
http://link.springer.com/article/10.1038/s41598-019-40808-y

المؤلفون: Julia P. Gerber, Jenny Russ, Vijay Chandrasekar, Nina Offermann, Hang-Mao Lee, Sarah Spear, Nicola Guzzi, Simona Maida, Sundararaghavan Pattabiraman, Ruoyu Zhang, Amir H. Kayvanjoo, Preeta Datta, Jagath Kasturiarachchi, Teresa Sposito, Natalia Izotova, Kristian Händler, Peter D. Adams, Teresa Marafioti, Tariq Enver, Jörg Wenzel, Marc Beyer, Elvira Mass, Cristian Bellodi, Joachim L. Schultze, Melania Capasso, Rachael Nimmo, Paolo Salomoni

المصدر: Nature cell biology 23(12), 1224-1239 (2021). doi:10.1038/s41556-021-00774-y
Nature Cell Biology

مصطلحات موضوعية: proto-oncogene protein Spi-1, metabolism [Histones], congenital [Leukocyte Disorders], Retroelements, Daxx protein, mouse, genetics [Autoimmune Diseases], genetics [Co-Repressor Proteins], Skin Diseases, cytology [Hematopoietic Stem Cells], Article, Autoimmune Diseases, Cell Line, Histones, Mice, genetics [Molecular Chaperones], ddc:570, Proto-Oncogene Proteins, Animals, Humans, genetics [Myelopoiesis], metabolism [Proto-Oncogene Proteins], metabolism [Trans-Activators], pathology [Skin Diseases], pathology [Inflammation], Inflammation, Myelopoiesis, pathology [Leukocyte Disorders], Mice, Knockout, immunology [Skin Diseases], B-Lymphocytes, Haematopoietic stem cells, genetics [Skin Diseases], Chronic inflammation, Cell Biology, cytology [B-Lymphocytes], Hematopoietic Stem Cells, pathology [Chromatin], Chromatin, pathology [Autoimmune Diseases], Mice, Inbred C57BL, genetics [Chromatin], genetics [Retroelements], Trans-Activators, Co-Repressor Proteins, Leukocyte Disorders, Molecular Chaperones

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee13b2bcc75258f28371f3d227cfcfb
https://pub.dzne.de/record/163640

المؤلفون: Jutta Ludwig-Müller, Tara L. Walker, Zeina Nicola, Merve Bulut, Gerd Kempermann, Alex M. Sykes, Leonardo Ortiz-López, Rupert W. Overall, Muhammad Ichwan, Vijay S. Adusumilli, Gerardo Ramírez-Rodríguez, Christoph Böttcher, Norbert Hubner, Enrique A. Lugo-Hernández

المصدر: Stem cell reports 16(3), 548-565 (2021). doi:10.1016/j.stemcr.2021.01.005
Stem Cell Reports

مصطلحات موضوعية: 0301 basic medicine, Male, Neural precursor cell proliferation, drug effects [Cell Cycle], pharmacology [Quercetin], drug effects [Hippocampus], hippocampus, metabolism [Receptors, G-Protein-Coupled], Apple peel, drug effects [Neurogenesis], Hippocampal formation, Biochemistry, Antioxidants, Receptors, G-Protein-Coupled, quercetin, chemistry.chemical_compound, Mice, 0302 clinical medicine, Hydroxybenzoates, chemistry [Fruit], dentate gyrus, pharmacology [Resorcinols], drug effects [Cell Differentiation], Cell Cycle, Neurogenesis, Cell Differentiation, pharmacology [Flavonoids], Cell biology, adult neurogenesis, Malus, metabolism [Proto-Oncogene Proteins c-akt], Female, chemistry [Malus], Quercetin, Signal Transduction, Cell Survival, drug effects [Cell Survival], Biology, pharmacology [Hydroxybenzoates], Article, 03 medical and health sciences, Precursor cell, Genetics, pharmacology [Antioxidants], Animals, ddc:610, mouse, Cell Proliferation, Flavonoids, drug effects [Cell Proliferation], Dentate gyrus, Flesh, fungi, Resorcinols, Cell Biology, Mice, Inbred C57BL, 030104 developmental biology, chemistry, Cardiovascular and Metabolic Diseases, Fruit, Proto-Oncogene Proteins c-akt, 3,5-dihydroxybenzoic acid, 030217 neurology & neurosurgery, neural precursor cells, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e15b0ea64c8d6286e334014b640ae6b
https://pub.dzne.de/record/157719

المؤلفون: Patrick Yu-Wai-Man, Christoph Ufer, Lynn Bedford, David J. Boocock, Theodosis S. Theodosi, Aslihan Ugun-Klusek, Julia C. Fitzgerald, E. Ellen Billett, Florence Burté

المساهمون: Yu Wai Man, Patrick [0000-0001-7847-9320], Apollo - University of Cambridge Repository

المصدر: Redox Biology, Vol 20, Iss, Pp 167-181 (2019)
Redox Biology 20, 167-181 (2019). doi:10.1016/j.redox.2018.10.003
Redox Biology

مصطلحات موضوعية: SDS-PAGE, sodium dodecyl sulphate-polyacrylamide gel, Proteomics, 0301 basic medicine, genetics [Neuroblastoma], Proteome, CCCP, carbonyl cyanide 3-chlorophenylhydrazone, Clinical Biochemistry, genetics [Monoamine Oxidase], Fluorescent Antibody Technique, Gene Expression, mtDNA, Mitochondrial DNA, Protein oxidation, PD, Parkinson's disease, Biochemistry, DPBS, Dulbecco's Phosphate Buffered Saline, NADH, ß-Nicotinamide adenine dinucleotide, Neuroblastoma, 0302 clinical medicine, metabolism [Reactive Oxygen Species], Phosphorylation, lcsh:QH301-705.5, chemistry.chemical_classification, lcsh:R5-920, metabolism [Proto-Oncogene Proteins c-bcl-2], biology, Neurodegeneration, Immunohistochemistry, Mitochondria, 3. Good health, Cell biology, DMEM/F12, Dulbecco's Modified Eagles Medium/Ham's F-12 nutrient mixture, monoamine oxidase A, human, Proto-Oncogene Proteins c-bcl-2, Caspases, RT, room temperature, Monoamine oxidase A, lcsh:Medicine (General), Oxidation-Reduction, Research Paper, MAO, monoamine oxidase, BCL2 protein, human, DCDHF, 2′,7′-Dichlorodihydroflourescein diacetate, Cell Survival, Monoamine oxidase, ETC, electron transport chain, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), metabolism [Neuroblastoma], SEM, standard error of the mean, Models, Biological, 03 medical and health sciences, ROS, reactive oxygen species, PBS, phosphate buffered saline, ddc:570, Cell Line, Tumor, Autophagy, medicine, Het, dihydroethidium, metabolism [Caspases], Humans, metabolism [Monoamine Oxidase], Monoamine Oxidase, LDH, Lactate dehydrogenase, Reactive oxygen species, Ac-DEVD-AMC, Acetyl-Asp-Glu-Val-Asp-7-amido-methyl coumarin, DMEM, Dulbecco's Modified Eagles Medium, Organic Chemistry, ATP, adenosine-5′-triphosphate, metabolism [Mitochondria], medicine.disease, Oxidative Stress, 030104 developmental biology, Monoamine neurotransmitter, chemistry, lcsh:Biology (General), DNPH, 2,4-Dinitrophenylhydrazine, DTT, dithiothreitol, biology.protein, qRT-PCR, quantitative reverse transcription PCR, genetics [Mitochondria], methods [Proteomics], Reactive Oxygen Species, 2-DG, 2-deoxy-D-glucose, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee6c7f7a07ce2d77e3885777776be6e
http://www.sciencedirect.com/science/article/pii/S2213231718307341

المؤلفون: Matthews, L., Berry, A., Ohanian, V., Ohanian, J., Garside, H., Ray, David

المصدر: Matthews , L , Berry , A , Ohanian , V , Ohanian , J , Garside , H & Ray , D 2008 , ' Caveolin mediates rapid glucocorticoid effects and couples glucocorticoid action to the antiproliferative program ' , Molecular Endocrinology , vol. 22 , no. 6 , pp. 1320-1330 . https://doi.org/10.1210/me.2007-0154

مصطلحات موضوعية: metabolism: 1-Phosphatidylinositol 3-Kinase, Animals, metabolism: Caveolin 1, drug effects: Cell Cycle, metabolism: Cell Membrane, drug effects: Cell Proliferation, Cells, Cultured, pharmacology: Dexamethasone, pharmacology: Glucocorticoids, Humans, drug effects: Membrane Microdomains, Mice, Phosphorylation, Protein Binding, metabolism: Proto-Oncogene Proteins c-akt, physiology: Proto-Oncogene Proteins pp60(c-src), metabolism: Receptors, Glucocorticoid, drug effects: Signal Transduction, Time Factors, Transcriptional Activation

وصف الملف: application/octet-stream

الاتاحة: https://research.manchester.ac.uk/en/publications/87e75a0d-a26d-43bd-a582-87504d257ab6
https://doi.org/10.1210/me.2007-0154
https://pure.manchester.ac.uk/ws/files/30192053/POST-PEER-REVIEW-PUBLISHERS-DOCUMENT.PDF
http://mend.endojournals.org/cgi/reprint/22/6/1320

المؤلفون: Pesse, B., Levrand, S., Feihl, F., Waeber, B., Gavillet, B., Pacher, P., Liaudet, L.

المصدر: Journal of Molecular and Cellular Cardiology, vol. 38, no. 5, pp. 765-75

مصطلحات موضوعية: Animals Cell Line Enzyme Activation/drug effects Extracellular Signal-Regulated MAP Kinases/*metabolism JNK Mitogen-Activated Protein Kinases/metabolism MAP Kinase Signaling System/drug effects Mitogen-Activated Protein Kinase Kinases/*metabolism Myocytes, Cardiac/*drug effects/*metabolism Oxidants/toxicity Peroxynitrous Acid/*toxicity Proto-Oncogene Proteins c-raf/*metabolism Proto-Oncogene Proteins p21(ras)/metabolism Rats Receptor, Epidermal Growth Factor/metabolism p38 Mitogen-Activated Protein Kinases/metabolism

وصف الملف: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/15850570; info:eu-repo/semantics/altIdentifier/pissn/0022-2828; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_84752A80AD1A7; https://serval.unil.ch/notice/serval:BIB_84752A80AD1A; https://serval.unil.ch/resource/serval:BIB_84752A80AD1A.P001/REF.pdf

الاتاحة: https://serval.unil.ch/notice/serval:BIB_84752A80AD1A
https://doi.org/10.1016/j.yjmcc.2005.02.020
https://serval.unil.ch/resource/serval:BIB_84752A80AD1A.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_84752A80AD1A7

المؤلفون: Pantoja-Escobar, Gerardo, Morales-Martínez, Mario, Vega, Gabriel G, Castro-Escarpulli, Graciela, Vega, Mario I

المصدر: Leukemia & lymphoma, vol 60, iss 4

مصطلحات موضوعية: drug effects [Cell Cycle], chemistry [Porins], metabolism [p38 Mitogen-Activated Protein Kinases], Tumor, metabolism [YY1 Transcription Factor], drug effects [Cell Survival], chemistry [CD40 Ligand], Molecular Mimicry, chemistry [Peptides], chemical and pharmacologic phenomena, hemic and immune systems, drug effects [Apoptosis], Cell Line, metabolism [Proto-Oncogene Proteins c-bcl-6], metabolism [CD40 Antigens], chemistry [Antineoplastic Agents], metabolism [Caspases], Humans, pharmacology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______325::11744bdba315bcc5a30e1bf34940aef0
https://escholarship.org/uc/item/3nj9g30m

المؤلفون: Josef Priller, Steffen Jung, Slava Epelman, Nora Hagemeyer, Sten Linnarsson, Marta Joana Costa Jordão, Fabio M.V. Rossi, Martin Kerschensteiner, Katrin Kierdorf, Fabiola Prutek, Frederic Geissmann, Lukas Amann, Tobias Goldmann, Robert Zeiser, Martin Krueger, Giuseppe Locatelli, Ori Staszewski, Peter Wieghofer, Ingo Bechmann, Marco Prinz, Hannah Hochgerner, Kathrin Frenzel

المصدر: Nature immunology 17(7), 797-805 (2016). doi:10.1038/ni.3423

مصطلحات موضوعية: Central Nervous System, 0301 basic medicine, genetics [Trans-Activators], Cellular differentiation, Monocytes, Mice, Immunology and Allergy, metabolism [Trans-Activators], MYELOID CELLS, physiology [Hematopoietic Stem Cells], IN-VIVO, Cells, Cultured, Mice, Knockout, MOUSE-BRAIN, CARDIAC MACROPHAGES, Microglia, Cell Differentiation, Cell biology, ALZHEIMERS-DISEASE, medicine.anatomical_structure, 1107 Immunology, TISSUE MACROPHAGES, Choroid plexus, Life Sciences & Biomedicine, proto-oncogene protein Spi-1, Parabiosis, Immunology, Central nervous system, Mice, Transgenic, Biology, DENDRITIC CELLS, immunology [Monocytes], 03 medical and health sciences, Immune system, Proto-Oncogene Proteins, medicine, Animals, metabolism [Proto-Oncogene Proteins], HEMATOPOIETIC STEM-CELLS, ddc:610, Transcription factor, Science & Technology, immunology [Central Nervous System], Macrophages, MICROGLIAL CELLS, physiology [Macrophages], Hematopoietic Stem Cells, physiology [Microglia], Mice, Inbred C57BL, 030104 developmental biology, Neuroimmunology, Microscopy, Fluorescence, CHOROID-PLEXUS, Trans-Activators, genetics [Proto-Oncogene Proteins]

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80e27dc8425e610ce09399e4c9e73a1c
https://doi.org/10.1038/ni.3423

المؤلفون: Muhammad Ichwan, Gerd Kempermann, Alex M. Sykes, Susann Ruhwald, Tara L. Walker, Steffen Vogler, Rupert W. Overall, Klaus Fabel, Daniela Lasse

المصدر: Stem Cell Reports
Stem Cell Reports, Vol 6, Iss 4, Pp 552-565 (2016)
Stem cell reports 6(4), 552-565 (2016). doi:10.1016/j.stemcr.2016.03.002

مصطلحات موضوعية: 0301 basic medicine, Male, pharmacology [Lysophospholipids], metabolism [Stem Cells], metabolism [Hippocampus], Cell Separation, Hippocampal formation, Biochemistry, Hippocampus, Running, cytology [Dentate Gyrus], Receptors, Lysophosphatidic Acid, Extracellular Signal-Regulated MAP Kinases, lcsh:QH301-705.5, Cells, Cultured, education.field_of_study, lcsh:R5-920, Microscopy, Confocal, Reverse Transcriptase Polymerase Chain Reaction, Stem Cells, Neurogenesis, metabolism [Dentate Gyrus], drug effects [Stem Cells], Cell biology, genetics [Receptors, Lysophosphatidic Acid], metabolism [Proto-Oncogene Proteins c-akt], Female, metabolism [Receptors, Lysophosphatidic Acid], Stem cell, lcsh:Medicine (General), metabolism [Biomarkers], Signal Transduction, drug effects [Signal Transduction], Population, Blotting, Western, Green Fluorescent Proteins, Mice, Transgenic, Biology, cytology [Stem Cells], Article, 03 medical and health sciences, Precursor cell, Genetics, genetics [Green Fluorescent Proteins], Animals, ddc:610, education, Protein kinase B, Cell Proliferation, Dentate gyrus, Gene Expression Profiling, Cell Biology, Nestin, metabolism [Extracellular Signal-Regulated MAP Kinases], Mice, Inbred C57BL, 030104 developmental biology, Gene Ontology, lcsh:Biology (General), metabolism [Green Fluorescent Proteins], cytology [Hippocampus], Dentate Gyrus, Lysophospholipids, Proto-Oncogene Proteins c-akt, lysophosphatidic acid, Biomarkers, Developmental Biology, methods [Gene Expression Profiling]

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70674d519c5669d2edd766089c10578a

المؤلفون: Anton Ivanov, Vu Thao Quyen Le-Schulte, Christophe Bernard, Fabio Morellini, Ronny Eichler, Axel Neu, Stephan Lawrence Marguet, Igor Jakovcevski, Ileana L. Hanganu-Opatz, Dirk Isbrandt, Andrea Merseburg

المصدر: Nature medicine 21(12), 1436-1444 (2015). doi:10.1038/nm.3987

مصطلحات موضوعية: therapeutic use [Bumetanide], Male, Nervous system, drug effects [Body Weight], Time Factors, pathology [Nerve Net], Hippocampus, Hippocampal formation, Bioinformatics, pathology [Epilepsy], Epilepsy, Cognition, drug effects [Behavior, Animal], Solute Carrier Family 12, Member 2, Premovement neuronal activity, Bumetanide, Neurons, Behavior, Animal, KCNQ Potassium Channels, genetics [KCNQ Potassium Channels], Electroencephalography, pathology [CA1 Region, Hippocampal], metabolism [Solute Carrier Family 12, Member 2], General Medicine, medicine.anatomical_structure, metabolism [Neurons], drug effects [Cognition], drug effects [Growth and Development], Female, Growth and Development, medicine.symptom, Proto-Oncogene Proteins c-fos, medicine.drug, drug effects [Embryo, Mammalian], medicine.medical_specialty, pathology [Embryo, Mammalian], genetics [Epilepsy], genetics [Mutation], Inflammation, drug therapy [Epilepsy], Biology, metabolism [RNA, Messenger], General Biochemistry, Genetics and Molecular Biology, genetics [RNA, Messenger], Internal medicine, drug effects [Nerve Net], medicine, drug effects [Neurons], Animals, ddc:610, RNA, Messenger, pharmacology [Bumetanide], metabolism [Embryo, Mammalian], CA1 Region, Hippocampal, pathology [Inflammation], metabolism [KCNQ Potassium Channels], Body Weight, Antagonist, Embryo, Mammalian, medicine.disease, Mice, Inbred C57BL, Endocrinology, Animals, Newborn, metabolism [Proto-Oncogene Proteins c-fos], Mutation, Nerve Net

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99de2fcb9965b9b6f993ba22f2b06d6b
https://doi.org/10.1038/nm.3987

المؤلفون: Bastian Dislich, Stefan F. Lichtenthaler, Shuai Li, Thomas Brocker, Cord Brakebusch

المصدر: The journal of immunology 195(9), 4244-4256 (2015). doi:10.4049/jimmunol.1500676

مصطلحات موضوعية: RHOA, immunology [Bone Marrow Cells], immunology [rhoA GTP-Binding Protein], immunology [Dendritic Cells], Regulator, immunology [Signal Transduction], Apoptosis, immunology [bcl-Associated Death Protein], genetics [Homeostasis], Phosphatidylinositol 3-Kinases, metabolism [Spleen], immunology [Proto-Oncogene Proteins c-akt], Homeostasis, Immunology and Allergy, genetics [Cell Survival], Cells, Cultured, Mice, Knockout, Reverse Transcriptase Polymerase Chain Reaction, immunology [Apoptosis], Flow Cytometry, metabolism [CD11c Antigen], Cell biology, metabolism [Bone Marrow Cells], immunology [Cytokinesis], flt3 ligand protein, metabolism [Proto-Oncogene Proteins c-akt], immunology [Membrane Proteins], immunology [CD11c Antigen], bcl-Associated Death Protein, Signal transduction, metabolism [rhoA GTP-Binding Protein], Signal Transduction, Cell Survival, Blotting, Western, Immunology, Bone Marrow Cells, Mice, Transgenic, Biology, genetics [Signal Transduction], immunology [Spleen], metabolism [Dendritic Cells], immunology [Homeostasis], Animals, genetics [Cytokinesis], ddc:610, cytology [Spleen], genetics [Apoptosis], Protein kinase B, metabolism [Phosphatidylinositol 3-Kinases], PI3K/AKT/mTOR pathway, Cell Proliferation, Cytokinesis, immunology [Cell Survival], immunology [Phosphatidylinositol 3-Kinases], metabolism [bcl-Associated Death Protein], Membrane Proteins, Dendritic Cells, Dendritic cell, genetics [rhoA GTP-Binding Protein], CD11c Antigen, biology.protein, rhoA GTP-Binding Protein, genetics [Cell Proliferation], Proto-Oncogene Proteins c-akt, Spleen, metabolism [Membrane Proteins]

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062533a50ce7aa260bb62a1f7060ab96
https://doi.org/10.4049/jimmunol.1500676

المؤلفون: Martin K.-H. Schäfer, Eberhard Weihe, Ursula Keber, Günter U. Höglinger, Martin Klietz, Thomas Carlsson, Wolfgang H. Oertel, Candan Depboylu

المصدر: Neuroscience 298, 302-317 (2015). doi:10.1016/j.neuroscience.2015.04.021

مصطلحات موضوعية: Male, Dyskinesia, Drug-Induced, Parkinson's disease, adverse effects [Levodopa], Striatum, Functional Laterality, Antiparkinson Agents, Levodopa, Mice, drug effects [Medial Forebrain Bundle], injuries [Medial Forebrain Bundle], etiology [Dyskinesia, Drug-Induced], Medial forebrain bundle, Neurons, Serotonin Plasma Membrane Transport Proteins, metabolism [Serotonin Plasma Membrane Transport Proteins], General Neuroscience, Parkinson Disease, metabolism [Neurons], etiology [Parkinson Disease], Proto-Oncogene Proteins c-fos, medicine.drug, pathology [Corpus Striatum], Tyrosine 3-Monooxygenase, Slc6a4 protein, mouse, Biology, Serotonergic, Statistics, Nonparametric, Midbrain, pharmacology [Amphetamine], Dopamine, adverse effects [Antiparkinson Agents], medicine, Animals, ddc:610, Oxidopamine, pathology [Dyskinesia, Drug-Induced], metabolism [Phosphopyruvate Hydratase], Tyrosine hydroxylase, physiology [Functional Laterality], Medial Forebrain Bundle, medicine.disease, toxicity [Oxidopamine], drug therapy [Parkinson Disease], Corpus Striatum, Abnormal involuntary movement, metabolism [Tyrosine 3-Monooxygenase], Mice, Inbred C57BL, Amphetamine, Disease Models, Animal, nervous system, metabolism [Proto-Oncogene Proteins c-fos], Phosphopyruvate Hydratase, Neuroscience

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20049f1540beb207c7ba722153abfbc0
https://doi.org/10.1016/j.neuroscience.2015.04.021

المؤلفون: Ferrari, María E, Bernis, María E, McLeod, Faye, Podpolny, Marina, Coullery, Romina P, Casadei, Inelia M, Salinas, Patricia C, Rosso, Silvana B

المصدر: Journal of cell science 131(13), jcs216101 (2018). doi:10.1242/jcs.216101

مصطلحات موضوعية: enzymology [Dendrites], MAP Kinase Kinase 4, metabolism [Receptors, G-Protein-Coupled], Dishevelled Proteins, metabolism [Hippocampus], genetics [Dishevelled Proteins], Hippocampus, Fzd7 protein, mouse, Receptors, G-Protein-Coupled, genetics [Calcium-Calmodulin-Dependent Protein Kinase Type 2], genetics [Dendrites], Mice, metabolism [Wnt Proteins], ddc:570, Proto-Oncogene Proteins, Neurites, metabolism [Dishevelled Proteins], genetics [MAP Kinase Kinase 4], Animals, metabolism [Dendrites], metabolism [Proto-Oncogene Proteins], Rats, Wistar, Wnt Signaling Pathway, genetics [Receptors, G-Protein-Coupled], genetics [Wnt Proteins], metabolism [Calcium-Calmodulin-Dependent Protein Kinase Type 2], metabolism [Neurites], Wnt7b protein, mouse, Dendrites, metabolism [MAP Kinase Kinase 4], growth & development [Hippocampus], Frizzled Receptors, Rats, Mice, Inbred C57BL, Wnt Proteins, Dvl1 protein, mouse, genetics [Proto-Oncogene Proteins], Calcium-Calmodulin-Dependent Protein Kinase Type 2, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e646ece2d75028bea919a5c5ddcdb46d
https://pubmed.ncbi.nlm.nih.gov/29898920

المؤلفون: Jochen Roeper, Dirk Isbrandt, Maria Jelena Hauser

المصدر: Behavioural brain research 332, 316-326 (2017). doi:10.1016/j.bbr.2017.06.013

مصطلحات موضوعية: 0301 basic medicine, Male, physiology [Recognition, Psychology], medicine.medical_treatment, Memory, Episodic, Context (language use), metabolism [Parvalbumins], 03 medical and health sciences, Behavioral Neuroscience, 0302 clinical medicine, pathology [Brain], medicine, Animals, ddc:610, Antipsychotic, Episodic memory, pathology [Schizophrenia], Working memory, Novelty, Brain, Recognition, Psychology, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Parvalbumins, Phenotype, metabolism [Brain], metabolism [Proto-Oncogene Proteins c-fos], Dopamine receptor, Schizophrenia, Endophenotype, Chronic Disease, Exploratory Behavior, metabolism [Schizophrenia], Ketamine, Schizophrenic Psychology, Psychology, Neuroscience, Proto-Oncogene Proteins c-fos, 030217 neurology & neurosurgery, physiology [Exploratory Behavior], Clinical psychology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d08b39ab5a8168a38ad1f1dcf50b120
https://pubmed.ncbi.nlm.nih.gov/28634108

المؤلفون: Sudhir Krishna, Michael Rehman, P. Rema, S. Lakshmi, B.K.M. Reddy, M. Radhakrishna Pillai, Geetashree Mukherjee, Bharathi Ramdass, Pradip Nair, Tessy Thomas Maliekal

المصدر: Gynecologic Oncology. 104:352-361

مصطلحات موضوعية: Pathology, Nude, Cell, Regulator, Uterine Cervical Neoplasms, biosynthesis/genetics, Mice, Phosphatidylinositol 3-Kinases, genetics/metabolism/pathology, Animals, Carcinoma, Squamous Cell, genetics/metabolism/pathology, Cell Line, Tumor, Cell Nucleus, metabolism, Cervical Intraepithelial Neoplasia, genetics/metabolism/pathology, Disease Progression, Female, Humans, Immunohistochemistry, Mice, Mice, Nude, NF-kappa B, biosynthesis/genetics/metabolism, Phosphatidylinositol 3-Kinases, metabolism, Proto-Oncogene Proteins c-akt, metabolism, Proto-Oncogene Proteins c-fos, biosynthesis/genetics, Receptor, Notch1, biosynthesis/genetics/metabolism, Signal Transduction, Transplantation, Heterologous, Tumor Suppressor Protein p53, biosynthesis/genetics, Uterine Cervical Neoplasms, Receptor, Notch1, HES1, Cervical cancer, Heterologous, Tumor, NF-kappa B, Obstetrics and Gynecology, Immunohistochemistry, medicine.anatomical_structure, Oncology, Carcinoma, Squamous Cell, Disease Progression, Female, Signal transduction, Proto-Oncogene Proteins c-fos, Receptor, Signal Transduction, medicine.medical_specialty, Transplantation, Heterologous, Mice, Nude, Biology, biosynthesis/genetics/metabolism, Cell Line, Cell Line, Tumor, medicine, Animals, Humans, Cervical Intraepithelial Neoplasia, Cell Nucleus, Transplantation, Carcinoma, Uterine Cervical Dysplasia, medicine.disease, Cell culture, Cancer research, Tumor Suppressor Protein p53, metabolism, Proto-Oncogene Proteins c-akt

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c140239f3ecca7f4472df384110c0ad2
https://doi.org/10.1016/j.ygyno.2006.08.054

المؤلفون: Robert A. Hipskind, Manuel S. Rodriguez, Guillaume Bossis, Rosa Farràs, Elisabetta Andermarcher, Stefan Müller, Marc Piechaczyk, Isabelle Jariel-Encontre, Darja Schmidt, Cécile E. Malnou

المساهمون: Institut de Génétique Moléculaire de Montpellier (IGMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)

المصدر: Molecular and Cellular Biology
Molecular and Cellular Biology, American Society for Microbiology, 2005, 25 (16), pp.6964--79. ⟨10.1128/MCB.25.16.6964-6979.2005⟩

مصطلحات موضوعية: Threonine, Time Factors, SUMO-1 Protein, Transcription, Genetic, Proto-Oncogene Proteins c-jun, Lysine, SUMO protein, Gene Expression, Plasma protein binding, Transactivation, 0302 clinical medicine, Phosphorylation, Luciferases, Glutathione Transferase, Mitogen-Activated Protein Kinase 1, 0303 health sciences, Mitogen-Activated Protein Kinase 3, Fluorescence Mitogen-Activated Protein Kinase 1/metabolism Mitogen-Activated Protein Kinase 3/metabolism Mutagenesis, Cell biology, Gene Expression Regulation, Neoplastic, Biochemistry, 030220 oncology & carcinogenesis, Small Ubiquitin-Related Modifier Proteins, Neoplastic Glutathione Transferase/metabolism Hela Cells Humans Immunoblotting Immunoprecipitation Kinetics Luciferases/metabolism Lysine/chemistry Microscopy, Dimerization, Proto-Oncogene Proteins c-fos, Protein Binding, Subcellular Fractions, Transcriptional Activation, Immunoprecipitation, Recombinant Fusion Proteins, Immunoblotting, Down-Regulation, Genetic Transfection, Protein degradation, Biology, Transfection, Proto-Oncogene Proteins p21(ras), Binding Sites Dimerization *Down-Regulation *Gene Expression Regulation, 03 medical and health sciences, Tertiary Proto-Oncogene Proteins c-fos/*metabolism Proto-Oncogene Proteins c-jun/chemistry/*metabolism Proto-Oncogene Proteins p21(ras)/metabolism Recombinant Fusion Proteins/chemistry SUMO-1 Protein/metabolism Small Ubiquitin-Related Modifier Proteins/metabolism Subcellular Fractions Threonine/chemistry Time Factors Trans-Activation (Genetics) Transcription Factor AP-1/chemistry/*metabolism Transcription, Humans, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Molecular Biology, 030304 developmental biology, Binding Sites, Cell Biology, Site-Directed Phosphorylation Protein Binding Protein Structure, Protein Structure, Tertiary, Transcription Factor AP-1, Kinetics, Microscopy, Fluorescence, Mutagenesis, Site-Directed, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a009d8327ae4e750871e9b3eb0985d58
https://doi.org/10.1128/mcb.25.16.6964-6979.2005

المؤلفون: Gizem Inak, Luming Zhou, Jeanne Christophe Marine, Magali Cucchiarini, Arnau Hervera, Yashashree Joshi, Khizr I. Rathore, Mohamed Y. Elnaggar, Simone Di Giovanni, Giorgia Quadrato, Radhika Puttagunta, Marilia Grando Sória

المساهمون: Wings for Life Spinal Cord Research Foundation, International Spinal Research Trust

المصدر: Brain 138(7), 1843-1862 (2015). doi:10.1093/brain/awv125

مصطلحات موضوعية: p53, metabolism [Axons], CORTICOSPINAL TRACT, metabolism [Spinal Cord Injuries], ACTIVATION, Mice, Mdm4 protein, mouse, Ubiquitin, spinal cord injury, regeneration, IGF1R, physiopathology [Spinal Cord Injuries], SPINAL-CORD-INJURY, Insulin-Like Growth Factor I, metabolism [Insulin-Like Growth Factor I], Spinal cord injury, IN-VIVO, pathology [Axons], biology, Reverse Transcriptase Polymerase Chain Reaction, metabolism [Proto-Oncogene Proteins c-mdm2], P53 PATHWAY, Proto-Oncogene Proteins c-mdm2, 11 Medical And Health Sciences, Flow Cytometry, ADULT CNS, Immunohistochemistry, FAMILY-MEMBERS, medicine.anatomical_structure, Optic nerve, Mdm2, Mdm2 protein, mouse, pathology [Spinal Cord Injuries], Life Sciences & Biomedicine, Signal Transduction, physiopathology [Optic Nerve Injuries], GROWTH CONE COLLAPSE, Nerve Crush, Ubiquitin-Protein Ligases, Central nervous system, Immunoblotting, Clinical Neurology, NEURITE OUTGROWTH, Retinal ganglion, optic nerve, 17 Psychology And Cognitive Sciences, MDM4, metabolism [Ubiquitin-Protein Ligases], MDM2, Proto-Oncogene Proteins, physiology [Signal Transduction], medicine, Animals, Immunoprecipitation, metabolism [Proto-Oncogene Proteins], ddc:610, Spinal Cord Injuries, metabolism [Optic Nerve Injuries], Science & Technology, Neurology & Neurosurgery, Regeneration (biology), Neurosciences, Computational Biology, Recovery of Function, pathology [Optic Nerve Injuries], Spinal cord, medicine.disease, insulin-like growth factor-1, mouse, spinal cord injury, Axons, Mice, Mutant Strains, Nerve Regeneration, Mice, Inbred C57BL, Disease Models, Animal, physiology [Recovery of Function], physiology [Nerve Regeneration], regeneration, Optic Nerve Injuries, biology.protein, metabolism [Tumor Suppressor Protein p53], Neurology (clinical), Neurosciences & Neurology, Tumor Suppressor Protein p53, Transcriptome, Neuroscience, OPTIC-NERVE

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9d6ce6150b2210eb3d327f7076625f
https://pubmed.ncbi.nlm.nih.gov/26747856

المؤلفون: Karsten Boldt, David Romano, Mohamed Ali Jarboui, Walter Kolch, Yves Texier, Nicola Horn, Alex von Kriegsheim, Armin Zebisch, Christian Johannes Gloeckner, Marius Ueffing, Nora Rauch, Layal Dernayka

المساهمون: Interactions cellulaires neuroendocriniennes (ICN), Université de la Méditerranée - Aix-Marseille 2-Centre National de la Recherche Scientifique (CNRS), Centre de recherche en neurobiologie - neurophysiologie de Marseille (CRN2M), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Department of Protein Science, Helmholtz Zentrum München = German Research Center for Environmental Health, Division of Experimental Ophthalmology, Eberhard Karls Universität Tübingen = Eberhard Karls University of Tuebingen-Center of Ophthalmology-Medical Proteome Center, Conway Institute of Biomolecular and Biomedical Research [Dublin, Irlande], University College Dublin [Dublin] (UCD), Systems Biology Ireland, School of Medicine and Medical Science [Dublin, Irlande], German Research Center for Environmental Health-Helmholtz-Zentrum München (HZM)

المصدر: Cellular Signalling
Cellular Signalling, 2016, 28 (9), pp.1432--1439. ⟨10.1016/j.cellsig.2016.06.016⟩
Dernayka, L, Rauch, N, Jarboui, M-A, Zebisch, A, Texier, Y, Horn, N, Romano, D, Gloeckner, C J, Kriegsheim, A V, Ueffing, M, Kolch, W & Boldt, K 2016, ' Autophosphorylation on S614 inhibits the activity and the transforming potential of BRAF ', Cellular Signalling, vol. 28, no. 9, pp. 1432-9 . https://doi.org/10.1016/j.cellsig.2016.06.016
Cellular signalling 28(9), 1432-1439 (2016). doi:10.1016/j.cellsig.2016.06.016

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Proto-Oncogene Proteins B-raf, endocrine system diseases, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, genetics [Mutation], medicine.disease_cause, Proto-Oncogene Mas, Cell Line, BRAF, 03 medical and health sciences, Mice, Phosphoserine, Inhibition of kinase activity and transformation, metabolism [Proto-Oncogene Proteins B-raf], medicine, metabolism [Phosphoserine], Animals, Humans, ddc:610, Amino Acid Sequence, Kinase activity, Phosphorylation, Protein kinase A, skin and connective tissue diseases, neoplasms, Mitogen-Activated Protein Kinase Kinases, Mutation, S614 autophosphorylation, biology, Chemistry, metabolism [Cell Transformation, Neoplastic], Autophosphorylation, Cell Biology, digestive system diseases, Rats, enzymes and coenzymes (carbohydrates), 030104 developmental biology, Cell Transformation, Neoplastic, Mitogen-activated protein kinase, chemistry [Proto-Oncogene Proteins B-raf], Cancer research, biology.protein, metabolism [Mitogen-Activated Protein Kinase Kinases], pathology [Cell Transformation, Neoplastic], V600E, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b926b99ebb81ba42e737a96a699f67
https://hal.science/hal-01474295