المؤلفون: Xiaopeng Peng (9136955), Ling Li (38566), Jingxuan Chen (5955893), Yichang Ren (9187354), Jin Liu (12833), Ziwen Yu (11971424), Hao Cao (2248066), Jianjun Chen (38177)

مصطلحات موضوعية: Molecular Biology, Pharmacology, Immunology, Cancer, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, without apparent toxicity, antitumor immune response, tumor growth inhibition, enhanced antitumor immunity, l1 expression levels, excellent hdac6 selectivity, xp5 , 12c , 16 – 2, potent hdac6 inhibitor, melanoma tumor model, 50 , l1 inhibitor, vivo <, increased tumor, efficiently enhanced, 50 mg, l1 immunotherapy, us recently, taken together, results suggest, resistant ycc3, phenylthiazole analogues

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_Novel_Histone_Deacetylase_6_HDAC6_Inhibitors_with_Enhanced_Antitumor_Immunity_of_Anti-PD-L1_Immunotherapy_in_Melanoma/18699914

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01863.s001

المؤلفون: Yichang Ren (9187354), Yuxi Wang (450170), Gang Li (34549), Zherong Zhang (10509103), Lingling Ma (421206), Binbin Cheng (9187351), Jianjun Chen (38177)

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Cancer, Hematology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, paclitaxel-resistant cancer cell line, compound 12 b, tumor growth inhibition rates, vivo antitumor efficacy, Tubulin Polymerization Inhibitors, 2.45 Å resolution, colchicine, mg, tubulin, 2780S IC 50, nM, Potent Anticancer Activities Novel ., IC 50 value, melanoma tumor model, 12 b

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_Novel_Benzimidazole_and_Indazole_Analogues_as_Tubulin_Polymerization_Inhibitors_with_Potent_Anticancer_Activities/14351464

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c01837.s001

المؤلفون: Paul Chen, Saifuddin Sheikh, Ateeq Ahmad, Shoukath M. Ali, Moghis U. Ahmad, Imran Ahmad

المصدر: Cellular & Molecular Biology Letters, Vol 23, Iss 1, Pp 1-7 (2018)

مصطلحات موضوعية: Endoxifen, Melanoma tumor model, Tamoxifen, Safety, Efficacy, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s11658-017-0068-7; https://doaj.org/toc/1425-8153; https://doaj.org/toc/1689-1392

URL الوصول: https://doaj.org/article/7a468221a1574ff68923d8751aacf3e1

المؤلفون: Yuxi Zhang, Chaoran Chen, Miao Su, Junxia Wang, Cheng Li, Xianzhu Yang

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Pharmacology, Immunology, Cancer, Virology, Computational Biology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, represent promising therapeutics, related gene inhibition, melanoma tumor model, l1 remarkably blocked, facile systemic delivery, expressing melanoma model, effective delivery system, robust immune response, rna relies heavily, mnp encapsulating sirna, mnp encapsulating, immune checkpoints, rna therapy, rna could, mnp exhibits, mnp ), delivering rna, viable approach

Relation: https://figshare.com/articles/journal_contribution/Hydrophobization_of_Ribonucleic_Acids_for_Facile_Systemic_Delivery_and_Multifaceted_Cancer_Immunotherapy/25016060

الاتاحة: https://doi.org/10.1021/acs.nanolett.3c04507.s001
https://figshare.com/articles/journal_contribution/Hydrophobization_of_Ribonucleic_Acids_for_Facile_Systemic_Delivery_and_Multifaceted_Cancer_Immunotherapy/25016060

المؤلفون: Xiaopeng Peng (9136955), Yichang Ren (9187354), Wanyi Pan (4257880), Jin Liu (12833), Jianjun Chen (38177)

مصطلحات موضوعية: Biochemistry, Pharmacology, Biotechnology, Immunology, Cancer, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, without apparent toxicity, sup >+, remarkable antiproliferative potency, l1 expression levels, tumor growth inhibition, melanoma tumor model, potential immunomodulatory effects, antitumor immune response, 1f , l1 inhibitor np, 50 , 6 , tumor tissues, immunopotentiating effects, antitumor cd8, 6 %), respectively ), potent compound, novel acridane, increased infiltration, hit compound, 5 μm

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_Novel_Acridane-Based_Tubulin_Polymerization_Inhibitors_with_Anticancer_and_Potential_Immunomodulatory_Effects/21727991

الاتاحة: https://doi.org/10.1021/acs.jmedchem.2c01566.s001

المؤلفون: Xiaopeng Peng (9136955), Jingxuan Chen (5955893), Ling Li (38566), Zhiqiang Sun (658262), Jin Liu (12833), Yichang Ren (9187354), Junli Huang (466990), Jianjun Chen (38177)

مصطلحات موضوعية: Biochemistry, Molecular Biology, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, B 16-F cancer cell migration, vivo antitumor efficacy, MS -275, IC 50 values, YCC, Potential Anticancer Agents Novel, cancer cell line, HDAC 3 activity, 15 c, compound 15 c, tubulin, SI, inhibitor, cancer cell lines, nM, agent, TGI, SMART, B 16-F melanoma tumor model

Relation: https://figshare.com/articles/journal_contribution/Efficient_Synthesis_and_Bioevaluation_of_Novel_Dual_Tubulin_Histone_Deacetylase_3_Inhibitors_as_Potential_Anticancer_Agents/14745492

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00413.s001