المؤلفون: Martha Sedegah (201887), Michael R. Hollingdale (8843579), Harini Ganeshan (83061), Maria Belmonte (201939), Jun Huang (127297), Arnel Belmonte (818807), Sandra Inoue (8985857), Rachel Velasco (8843570), Bradley Hickey (3546374), Nimfa Teneza-Mora (137221), Joanne Lumsden (364574), Sharina Reyes (201916), Jo Glenna Banania (8985845), Anatalio Reyes (8985848), Ivelese Guzman (8985863), Thomas L. Richie (8843582), Judith E. Epstein (8985875), Eileen Villasante (628418)

مصطلحات موضوعية: Immunology, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, dose, RAS, vaccine efficacy, malaria antigens CSP, vivo FluoroSpot assay, PfNF 54 sporozoites, Plasmodium falciparum malaria, CelTOS Background Immunization, IFN, subject, IL 2 responses, AMA, 27 weeks post-CHMI, protection, IMRAS, Trial registration ClinicalTrials.g., TRAP, radiation-attenuated Plasmodium fal., VE, Cohort 2 responses, 15 mer peptides

Relation: https://figshare.com/articles/journal_contribution/S1_Appendix_-/15832261

الاتاحة: https://doi.org/10.1371/journal.pone.0256396.s001

المؤلفون: Martha Sedegah (201887), Michael R. Hollingdale (8843579), Harini Ganeshan (83061), Maria Belmonte (201939), Jun Huang (127297), Arnel Belmonte (818807), Sandra Inoue (8985857), Rachel Velasco (8843570), Bradley Hickey (3546374), Nimfa Teneza-Mora (137221), Joanne Lumsden (364574), Sharina Reyes (201916), Jo Glenna Banania (8985845), Anatalio Reyes (8985848), Ivelese Guzman (8985863), Thomas L. Richie (8843582), Judith E. Epstein (8985875), Eileen Villasante (628418)

مصطلحات موضوعية: Immunology, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, dose, RAS, vaccine efficacy, malaria antigens CSP, vivo FluoroSpot assay, PfNF 54 sporozoites, Plasmodium falciparum malaria, CelTOS Background Immunization, IFN, subject, IL 2 responses, AMA, 27 weeks post-CHMI, protection, IMRAS, Trial registration ClinicalTrials.g., TRAP, radiation-attenuated Plasmodium fal., VE, Cohort 2 responses, 15 mer peptides

Relation: https://figshare.com/articles/figure/Cohort_1_and_Cohort_2_and_Cohort_1_hyper-immunized_Flow_diagram_of_immunizations_CHMI_and_PBMC_samples_/15832264

الاتاحة: https://doi.org/10.1371/journal.pone.0256396.g001

المؤلفون: Martha Sedegah (201887), Michael R. Hollingdale (8843579), Harini Ganeshan (83061), Maria Belmonte (201939), Jun Huang (127297), Arnel Belmonte (818807), Sandra Inoue (8985857), Rachel Velasco (8843570), Bradley Hickey (3546374), Nimfa Teneza-Mora (137221), Joanne Lumsden (364574), Sharina Reyes (201916), Jo Glenna Banania (8985845), Anatalio Reyes (8985848), Ivelese Guzman (8985863), Thomas L. Richie (8843582), Judith E. Epstein (8985875), Eileen Villasante (628418)

مصطلحات موضوعية: Immunology, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, dose, RAS, vaccine efficacy, malaria antigens CSP, vivo FluoroSpot assay, PfNF 54 sporozoites, Plasmodium falciparum malaria, CelTOS Background Immunization, IFN, subject, IL 2 responses, AMA, 27 weeks post-CHMI, protection, IMRAS, Trial registration ClinicalTrials.g., TRAP, radiation-attenuated Plasmodium fal., VE, Cohort 2 responses, 15 mer peptides

Relation: https://figshare.com/articles/figure/Cohorts_1_and_Cohort_2_IFN-_IL2_and_IFN-_IL2_activities_to_SPZ_after_each_immunization_and_CHMI_/15832267

الاتاحة: https://doi.org/10.1371/journal.pone.0256396.g002

المؤلفون: Martha Sedegah (201887), Michael R. Hollingdale (8843579), Harini Ganeshan (83061), Maria Belmonte (201939), Jun Huang (127297), Arnel Belmonte (818807), Sandra Inoue (8985857), Rachel Velasco (8843570), Bradley Hickey (3546374), Nimfa Teneza-Mora (137221), Joanne Lumsden (364574), Sharina Reyes (201916), Jo Glenna Banania (8985845), Anatalio Reyes (8985848), Ivelese Guzman (8985863), Thomas L. Richie (8843582), Judith E. Epstein (8985875), Eileen Villasante (628418)

مصطلحات موضوعية: Immunology, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, dose, RAS, vaccine efficacy, malaria antigens CSP, vivo FluoroSpot assay, PfNF 54 sporozoites, Plasmodium falciparum malaria, CelTOS Background Immunization, IFN, subject, IL 2 responses, AMA, 27 weeks post-CHMI, protection, IMRAS, Trial registration ClinicalTrials.g., TRAP, radiation-attenuated Plasmodium fal., VE, Cohort 2 responses, 15 mer peptides

Relation: https://figshare.com/articles/figure/Cohort_1_and_Cohort_2_Comparison_of_post-5_sup_th_sup_pre-CHMI_IFN-_IL2_and_IFN-_IL2_responses_to_SPZ_/15832270

الاتاحة: https://doi.org/10.1371/journal.pone.0256396.g003

المؤلفون: Martha Sedegah (201887), Michael R. Hollingdale (8843579), Harini Ganeshan (83061), Maria Belmonte (201939), Jun Huang (127297), Arnel Belmonte (818807), Sandra Inoue (8985857), Rachel Velasco (8843570), Bradley Hickey (3546374), Nimfa Teneza-Mora (137221), Joanne Lumsden (364574), Sharina Reyes (201916), Jo Glenna Banania (8985845), Anatalio Reyes (8985848), Ivelese Guzman (8985863), Thomas L. Richie (8843582), Judith E. Epstein (8985875), Eileen Villasante (628418)

مصطلحات موضوعية: Immunology, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, dose, RAS, vaccine efficacy, malaria antigens CSP, vivo FluoroSpot assay, PfNF 54 sporozoites, Plasmodium falciparum malaria, CelTOS Background Immunization, IFN, subject, IL 2 responses, AMA, 27 weeks post-CHMI, protection, IMRAS, Trial registration ClinicalTrials.g., TRAP, radiation-attenuated Plasmodium fal., VE, Cohort 2 responses, 15 mer peptides

Relation: https://figshare.com/articles/figure/Comparison_of_the_ratios_post-5_sup_th_sup_Post-4_sup_th_sup_IFN-_IL2_and_IFN-_IL2_responses_to_SPZ_of_individual_subjects_Cohort_1_and_Cohort_2_/15832273

الاتاحة: https://doi.org/10.1371/journal.pone.0256396.g004

المؤلفون: Martha Sedegah (201887), Michael R. Hollingdale (8843579), Harini Ganeshan (83061), Maria Belmonte (201939), Jun Huang (127297), Arnel Belmonte (818807), Sandra Inoue (8985857), Rachel Velasco (8843570), Bradley Hickey (3546374), Nimfa Teneza-Mora (137221), Joanne Lumsden (364574), Sharina Reyes (201916), Jo Glenna Banania (8985845), Anatalio Reyes (8985848), Ivelese Guzman (8985863), Thomas L. Richie (8843582), Judith E. Epstein (8985875), Eileen Villasante (628418)

مصطلحات موضوعية: Immunology, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, dose, RAS, vaccine efficacy, malaria antigens CSP, vivo FluoroSpot assay, PfNF 54 sporozoites, Plasmodium falciparum malaria, CelTOS Background Immunization, IFN, subject, IL 2 responses, AMA, 27 weeks post-CHMI, protection, IMRAS, Trial registration ClinicalTrials.g., TRAP, radiation-attenuated Plasmodium fal., VE, Cohort 2 responses, 15 mer peptides

Relation: https://figshare.com/articles/figure/Cohort_1_and_Cohort_2_IFN-_and_IL2_activities_to_CSP_AMA1_TRAP_and_CelTOS_after_each_immunization_and_CHMI_/15832276

الاتاحة: https://doi.org/10.1371/journal.pone.0256396.g005

المؤلفون: Martha Sedegah (201887), Michael R. Hollingdale (8843579), Harini Ganeshan (83061), Maria Belmonte (201939), Jun Huang (127297), Arnel Belmonte (818807), Sandra Inoue (8985857), Rachel Velasco (8843570), Bradley Hickey (3546374), Nimfa Teneza-Mora (137221), Joanne Lumsden (364574), Sharina Reyes (201916), Jo Glenna Banania (8985845), Anatalio Reyes (8985848), Ivelese Guzman (8985863), Thomas L. Richie (8843582), Judith E. Epstein (8985875), Eileen Villasante (628418)

مصطلحات موضوعية: Immunology, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, dose, RAS, vaccine efficacy, malaria antigens CSP, vivo FluoroSpot assay, PfNF 54 sporozoites, Plasmodium falciparum malaria, CelTOS Background Immunization, IFN, subject, IL 2 responses, AMA, 27 weeks post-CHMI, protection, IMRAS, Trial registration ClinicalTrials.g., TRAP, radiation-attenuated Plasmodium fal., VE, Cohort 2 responses, 15 mer peptides

Relation: https://figshare.com/articles/figure/Cohort_1_Higher_post-5_sup_th_sup_responses_to_SPZ_are_linked_to_post-5_sup_th_sup_IFN-_and_IL2_responses_to_CSP_AMA1_TRAP_and_CelTOS_/15832279

الاتاحة: https://doi.org/10.1371/journal.pone.0256396.g006

المؤلفون: Martha Sedegah (201887), Michael R. Hollingdale (8843579), Harini Ganeshan (83061), Maria Belmonte (201939), Jun Huang (127297), Arnel Belmonte (818807), Sandra Inoue (8985857), Rachel Velasco (8843570), Bradley Hickey (3546374), Nimfa Teneza-Mora (137221), Joanne Lumsden (364574), Sharina Reyes (201916), Jo Glenna Banania (8985845), Anatalio Reyes (8985848), Ivelese Guzman (8985863), Thomas L. Richie (8843582), Judith E. Epstein (8985875), Eileen Villasante (628418)

مصطلحات موضوعية: Immunology, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, dose, RAS, vaccine efficacy, malaria antigens CSP, vivo FluoroSpot assay, PfNF 54 sporozoites, Plasmodium falciparum malaria, CelTOS Background Immunization, IFN, subject, IL 2 responses, AMA, 27 weeks post-CHMI, protection, IMRAS, Trial registration ClinicalTrials.g., TRAP, radiation-attenuated Plasmodium fal., VE, Cohort 2 responses, 15 mer peptides

Relation: https://figshare.com/articles/figure/Cohort_2_Higher_post-5_sup_th_sup_protective_responses_to_sporozoites_are_linked_to_post-5_sup_th_sup_protective_IFN-_and_IL2_responses_to_CSP_AMA1_TRAP_and_CelTOS_/15832282

الاتاحة: https://doi.org/10.1371/journal.pone.0256396.g007

المؤلفون: Martha Sedegah (201887), Michael R. Hollingdale (8843579), Harini Ganeshan (83061), Maria Belmonte (201939), Jun Huang (127297), Arnel Belmonte (818807), Sandra Inoue (8985857), Rachel Velasco (8843570), Bradley Hickey (3546374), Nimfa Teneza-Mora (137221), Joanne Lumsden (364574), Sharina Reyes (201916), Jo Glenna Banania (8985845), Anatalio Reyes (8985848), Ivelese Guzman (8985863), Thomas L. Richie (8843582), Judith E. Epstein (8985875), Eileen Villasante (628418)

مصطلحات موضوعية: Immunology, Infectious Diseases, Virology, Computational Biology, Physical Sciences not elsewhere classified, dose, RAS, vaccine efficacy, malaria antigens CSP, vivo FluoroSpot assay, PfNF 54 sporozoites, Plasmodium falciparum malaria, CelTOS Background Immunization, IFN, subject, IL 2 responses, AMA, 27 weeks post-CHMI, protection, IMRAS, Trial registration ClinicalTrials.g., TRAP, radiation-attenuated Plasmodium fal., VE, Cohort 2 responses, 15 mer peptides

Relation: https://figshare.com/articles/figure/Cohort_1_hyperimmunized_subjects_IFN-_IL2_and_IFN-_IL2_responses_to_sporozoites_CSP_AMA1_TRAP_and_CelTOS_/15832285

الاتاحة: https://doi.org/10.1371/journal.pone.0256396.g008