المؤلفون: Henrich, Timothy J, Bosch, Ronald J, Godfrey, Catherine, Mar, Hanna, Nair, Apsara, Keefer, Michael, Fichtenbaum, Carl, Moisi, Daniela, Clagett, Brian, Buck, Amanda M, Deitchman, Amelia N, Aweeka, Francesca, Li, Jonathan Z, Kuritzkes, Daniel R, Lederman, Michael M, Hsue, Priscilla Y, Deeks, Steven G, Team, the ACTG A5337, Campbell, Danielle, Cutler, Corey, Dorosh, Michael, Ha, Belinda, Hawkins, Elizabeth, Hensel, Christopher, Khairalla, Nayri, Knowles, Kevin, Lee, Sulggi A, Pedersen, Susan, Ritz, Justin, Ryder, Dylan, Sekaly, Rafick, Shugarts, David L, Straub, Becky, Zolopa, Andrew

المصدر: Cell Reports Medicine. 5(10)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Immunology, Infectious Diseases, Sexually Transmitted Infections, HIV/AIDS, 5.1 Pharmaceuticals, 6.1 Pharmaceuticals, Infection, Good Health and Well Being, Humans, HIV Infections, HIV-1, CD8-Positive T-Lymphocytes, CD4-Positive T-Lymphocytes, DNA, Viral, Sirolimus, Male, Female, Adult, Middle Aged, Immune Checkpoint Proteins, Cell Cycle, Programmed Cell Death 1 Receptor, ACTG A5337 Team, HIV curative strategies, HIV immunology, HIV persistence, HIV reservoirs, antiproliferative medications, immunotherapy, intact proviral HIV-1 DNA, mTOR inhibition, sirolimus, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4sx4v665
https://escholarship.org/content/qt4sx4v665/qt4sx4v665.pdf

المؤلفون: Iryna Halabitska, Pavlo Petakh, Oleh Lushchak, Iryna Kamyshna, Valentyn Oksenych, Oleksandr Kamyshnyi

المصدر: Viruses, Vol 16, Iss 12, p 1938 (2024)

مصطلحات موضوعية: metformin, broad-spectrum antiviral, AMPK activation, mTOR inhibition, viral replication, oxidative stress, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1999-4915/16/12/1938; https://doaj.org/toc/1999-4915

URL الوصول: https://doaj.org/article/9fd5649820fa41179825e3ec1f333080

المؤلفون: Palma, Jose‐Alberto, Martinez, Jose, Vernetti, Patricio Millar, Ma, Thong, Perez, Miguel A, Zhong, Judy, Qian, Yingzhi, Dutta, Suman, Maina, Katherine N, Siddique, Ibrar, Bitan, Gal, Ades‐Aron, Benjamin, Shepherd, Timothy M, Kang, Un J, Kaufmann, Horacio

المصدر: Movement Disorders. 37(4)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Acquired Cognitive Impairment, Neurodegenerative, Brain Disorders, Clinical Research, Neurosciences, Clinical Trials and Supportive Activities, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Neurological, Double-Blind Method, Humans, Medical Futility, Multiple System Atrophy, Sirolimus, TOR Serine-Threonine Kinases, Treatment Outcome, alpha-Synuclein, mTOR inhibition, autophagy, neurodegeneration, synuclein, parkinsonism, Human Movement and Sports Sciences, Neurology & Neurosurgery, Clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7hz2z99n

المؤلفون: Kirkeby, Malene Helligsø, Bendstrup, Elisabeth, Rose, Hanne Krogh

المصدر: Kirkeby , M H , Bendstrup , E & Rose , H K 2024 , ' Case report : If it is not asthma—think of lymphangioleiomyomatosis in younger female patients ' , Frontiers in medicine , vol. 11 , 1328471 . https://doi.org/10.3389/fmed.2024.1328471

مصطلحات موضوعية: angiomyolipoma (AML), asthma, case report, high-resolution computed tomography (HRCT), lymphangioleiomyomatosis, mTOR inhibition (mTORi), perivascular epithelial cell tumor

Relation: https://pure.au.dk/portal/en/publications/32fa2291-5ef6-4f04-8732-093f004d3844

الاتاحة: https://pure.au.dk/portal/en/publications/32fa2291-5ef6-4f04-8732-093f004d3844
https://doi.org/10.3389/fmed.2024.1328471

المؤلفون: Cervantes, Renata Wellenkamp de Carvalho Freire de

المساهمون: Marques-Ramos, Ana, RCIPL

مصطلحات موضوعية: Via de sinalização mTOR, Cancro gástrico, mTOR, Diminuição da expressão proteica, Apigenina, mTOR signaling pathway, Gastric cancer, mTOR inhibition, Decreased protein expression, Apigenin

وصف الملف: application/pdf

Relation: Cervantes RW. mTOR expression regulation and new anticancer applications for apigenin [dissertation]. Lisboa: Escola Superior de Tecnologia da Saúde de Lisboa/Instituto Politécnico de Lisboa; 2022.

الاتاحة: http://hdl.handle.net/10400.21/14949

المؤلفون: Femke V. M. Mulder, Evelien F. H. I. Peeters, Jan Westerink, Fried J. T. Zwartkruis, Wendela L. de Ranitz-Greven

المصدر: Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-8 (2022)

مصطلحات موضوعية: Tuberous sclerosis complex, mTOR inhibition, Dyslipidemia, Hypercholesterolemia, Hyperglycemia, Adverse effects, Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1750-1172

URL الوصول: https://doaj.org/article/c90b1abef9fe4f0994da3c5b1a92569a

المؤلفون: Schnitzbauer, Andreas A., Filmann, Natalie, Adam, Rene, Bachellier, Philippe, Bechstein, Wolf O., Becker, Thomas, Bhoori, Sherrie, Bilbao, Itxarone, Brockmann, Jens, Burra, Patrizia, Chazoullieres, Olivier, Cillo, Umberto, Colledan, Michele, Duvoux, Christoph, Ganten, Tom M., Gugenheim, Jean, Heise, Michael, van Hoek, Bart, Jamieson, Neville, de Jong, Koert P., Klein, Christian G., Klempnauer, Jurgen, Kneteman, Norman, Lerut, Jan, Makisalo, Heikki, Mazzaferro, Vincenzo, Mirza, Darius F., Nadalin, Silvio, Neuhaus, Peter, Pageaux, George-Philippe, Pinna, Antonio D., Pirenne, Jaques, Pratschke, Johann, Powel, James, Rentsch, Markus, Rizell, Magnus, Rossi, Giorgio, Rostaing, Lionel, Roy, Andre, Scholz, Tim, Settmacher, Utz, Soliman, Thomas, Strasser, Simone, Soderdahl, Gunnar, Troisi, Roberto I., Sanchez Turrion, Victor, Schlitt, Hans J., Geissler, Edward K.

المصدر: Annals of Surgery. 272(5):855-862

مصطلحات موضوعية: AFP, Milan criteria, mTOR-inhibition, multivariate COX regression, Sirolimus

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-437449
https://doi.org/10.1097/SLA.0000000000004280

المؤلفون: Frouwke Veenstra, Lise M. Verhoef, Merel Opdam, Alfons A. den Broeder, Wing-Yee Kwok, Inger L. Meek, Cornelia H. M. van den Ende, Marcel Flendrie, Noortje van Herwaarden

المصدر: BMC Rheumatology, Vol 6, Iss 1, Pp 1-6 (2022)

مصطلحات موضوعية: Gout, Diabetes Mellites, Metformin, mTOR inhibition, Diseases of the musculoskeletal system, RC925-935

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2520-1026

URL الوصول: https://doaj.org/article/cbf6b93851664781b72edd639b1649ec

المؤلفون: Wencheng Fu, Geng Wu

المصدر: Molecules; Volume 28; Issue 7; Pages: 3157

مصطلحات موضوعية: senescence, aging, anti-aging, cancer, anti-cancer therapy, mTOR, mTOR inhibition

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/molecules28073157

الاتاحة: https://doi.org/10.3390/molecules28073157

المؤلفون: Besnard, Emilie, Hakre, Shweta, Kampmann, Martin, Lim, Hyung W, Hosmane, Nina N, Martin, Alyssa, Bassik, Michael C, Verschueren, Erik, Battivelli, Emilie, Chan, Jonathan, Svensson, J Peter, Gramatica, Andrea, Conrad, Ryan J, Ott, Melanie, Greene, Warner C, Krogan, Nevan J, Siliciano, Robert F, Weissman, Jonathan S, Verdin, Eric

المصدر: Cell Host & Microbe. 20(6)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Immunology, HIV/AIDS, Infectious Diseases, Genetics, Sexually Transmitted Infections, Infection, Adaptor Proteins, Signal Transducing, CD4-Positive T-Lymphocytes, Cell Line, Clustered Regularly Interspaced Short Palindromic Repeats, Cyclin-Dependent Kinase 9, Gene Expression Regulation, Viral, Gene Knockdown Techniques, Genes, Viral, HIV Infections, HIV-1, Humans, K562 Cells, Phosphorylation, Positive Transcriptional Elongation Factor B, RNA, Small Interfering, Signal Transduction, TOR Serine-Threonine Kinases, Transcription, Genetic, Virus Latency, mTOR Associated Protein, LST8 Homolog, tat Gene Products, Human Immunodeficiency Virus, MTOR Associated Protein, LST8 Homolog, HIV LTR, HIV latency, HIV transcription, genome-wide shRNA screen, latency reversal, mTOR inhibition, reactivation from latency, Microbiology, Biochemistry and cell biology, Medical microbiology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1jk6w9dr
https://escholarship.org/content/qt1jk6w9dr/qt1jk6w9dr.pdf

المؤلفون: Mulder, Femke V.M., Peeters, Evelien F.H.I., Westerink, Jan, Zwartkruis, Fried J.T., de Ranitz-Greven, Wendela L.

المساهمون: MS Interne Geneeskunde, Circulatory Health, CMM Groep Zwartkruis, Cancer

مصطلحات موضوعية: Adverse effects, Diabetes mellitus, Dyslipidemia, Hypercholesterolemia, Hyperglycemia, Long-term, mTOR inhibition, Tuberous sclerosis complex, Genetics(clinical), Pharmacology (medical)

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/448440

الاتاحة: https://dspace.library.uu.nl/handle/1874/448440

المؤلفون: Diane Evrard, Clément Dumont, Michel Gatineau, Jean-Pierre Delord, Jérôme Fayette, Chantal Dreyer, Annemilaï Tijeras-Raballand, Armand de Gramont, Jean-François Delattre, Muriel Granier, Nasredine Aissat, Marie-Line Garcia-Larnicol, Khemaies Slimane, Benoist Chibaudel, Eric Raymond, Christophe Le Tourneau, Sandrine Faivre

المصدر: Cancers; Volume 14; Issue 18; Pages: 4509

مصطلحات موضوعية: tumor microenvironment, mTOR inhibition, head and neck carcinoma, PI3K-AKT-mTOR pathway, interferon gamma

وصف الملف: application/pdf

Relation: Tumor Microenvironment; https://dx.doi.org/10.3390/cancers14184509

الاتاحة: https://doi.org/10.3390/cancers14184509

المؤلفون: Elena Cuadrado-Payán, Fritz Diekmann, David Cucchiari

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 14; Pages: 7707

مصطلحات موضوعية: kidney, transplant, kidney transplant, immunosuppression, mTOR, mTOR inhibition

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Biology; https://dx.doi.org/10.3390/ijms23147707

الاتاحة: https://doi.org/10.3390/ijms23147707

المؤلفون: Pereira, Miguel Oliveira

المساهمون: Marques-Ramos, Ana, RCIPL

مصطلحات موضوعية: Cancro gástrico, Via de sinalização mTOR, Morfolino, Inibição mTOR, Diminuição da expressão proteica, Gastric cancer, mTOR signaling pathway, Morpholino, mTOR inhibition, Decreased protein expression

وصف الملف: application/pdf

Relation: Pereira MO. Determinação da eficácia de um morfolino contra o mTOR na sobrevivência e proliferação de células de cancro gástrico [dissertation]. Lisboa: Escola Superior de Tecnologia da Saúde de Lisboa/Instituto Politécnico de Lisboa; 2020.

الاتاحة: http://hdl.handle.net/10400.21/12521

المؤلفون: Liu, Jinzhao, Lyu, Qingyang, Wu, Meicen, Zhou, Yang, Wang, Tianyi, Zhang, Yichi, Fan, Ni, Yang, Chang, Wang, Weiping

المصدر: Adv Healthc Mater ; ISSN:2192-2659 ; Volume:13 ; Issue:31

مصطلحات موضوعية: anti‐angiogenesis, carrier‐free nanoparticles, immunogenic cell death, mTOR inhibition, photodynamic therapy, synergistic effect

Relation: https://doi.org/10.1002/adhm.202402357; https://pubmed.ncbi.nlm.nih.gov/39235716; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11650419/

الاتاحة: https://doi.org/10.1002/adhm.202402357
https://pubmed.ncbi.nlm.nih.gov/39235716
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11650419/

المؤلفون: Beck, J Thaddeus, Hortobagyi, Gabriel N, Campone, Mario, Lebrun, Fabienne, Deleu, Ines, Rugo, Hope S, Pistilli, Barbara, Masuda, Norikazu, Hart, Lowell, Melichar, Bohuslav, Dakhil, Shaker, Geberth, Matthias, Nunzi, Martina, Heng, Daniel YC, Brechenmacher, Thomas, El-Hashimy, Mona, Douma, Shyanne, Ringeisen, Francois, Piccart, Martine

المصدر: Breast Cancer Research and Treatment. 143(3)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Clinical Trials and Supportive Activities, Cancer, Breast Cancer, Clinical Research, Aging, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Aged, Aged, 80 and over, Androstadienes, Antineoplastic Combined Chemotherapy Protocols, Breast Neoplasms, Clinical Trials as Topic, Disease-Free Survival, Everolimus, Female, Humans, Kaplan-Meier Estimate, Middle Aged, Neoplasm Recurrence, Local, Neoplasms, Hormone-Dependent, Receptors, Estrogen, Receptors, Progesterone, Sirolimus, BOLERO-2, Breast cancer, First-line therapy, Metastatic disease, mTOR inhibition, Clinical Sciences, Oncology & Carcinogenesis, Clinical sciences, Oncology and carcinogenesis

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4k58n3th

المؤلفون: María Iglesias-Escudero, David Sansegundo-Arribas, Paloma Riquelme, David Merino-Fernández, Sandra Guiral-Foz, Carmen Pérez, Rosalia Valero, Juan Carlos Ruiz, Emilio Rodrigo, Patricia Lamadrid-Perojo, James A. Hutchinson, Jordi Ochando, Marcos López-Hoyos

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, kidney transplantation, mTOR inhibition, myeloid-derived suppressor cells, tacrolimus, immunosuppression

Relation: https://figshare.com/articles/presentation/Presentation_1_Myeloid-Derived_Suppressor_Cells_in_Kidney_Transplant_Recipients_and_the_Effect_of_Maintenance_Immunotherapy_pptx/12219707

الاتاحة: https://doi.org/10.3389/fimmu.2020.00643.s001
https://figshare.com/articles/presentation/Presentation_1_Myeloid-Derived_Suppressor_Cells_in_Kidney_Transplant_Recipients_and_the_Effect_of_Maintenance_Immunotherapy_pptx/12219707

المؤلفون: Luqi Jin (10522384), Yu Chen (29959), Chunlan Yan (509106), Xiaoyuan Guo (657206), Tingting Jiang (169999), Ayiding Guli (6195920), Xinghui Song (10522387), Qun Wan (229959), Qiang Shu (447456), Shiping Ding (144701)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Physiology, Pharmacology, Developmental Biology, Cancer, Hematology, Chemical Sciences not elsewhere classified, mTOR inhibition, high-confidence phosphoproteome map, CDK 1 Activation, cell cycle-related substrates, Phosphoproteome Profiling Revealed, rapamycin, MAPK 3 kinases, cell cycle progression, Regulate Cell Cycle Progression, cell cycle events, kinase inhibitor treatment

Relation: https://figshare.com/articles/journal_contribution/Phosphoproteome_Profiling_Revealed_the_Importance_of_mTOR_Inhibition_on_CDK1_Activation_to_Further_Regulate_Cell_Cycle_Progression/14368384

الاتاحة: https://doi.org/10.1021/acs.jproteome.0c00848.s001

المؤلفون: María Iglesias-Escudero, David Sansegundo-Arribas, Paloma Riquelme, David Merino-Fernández, Sandra Guiral-Foz, Carmen Pérez, Rosalia Valero, Juan Carlos Ruiz, Emilio Rodrigo, Patricia Lamadrid-Perojo, James A. Hutchinson, Jordi Ochando, Marcos López-Hoyos

المصدر: Frontiers in Immunology, Vol 11 (2020)

مصطلحات موضوعية: kidney transplantation, mTOR inhibition, myeloid-derived suppressor cells, tacrolimus, immunosuppression, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.00643/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/af04e9aa6d044ea49755131b3716c429

المؤلفون: Andrew J. Browne, Marie L. Kubasch, Andy Göbel, Peyman Hadji, David Chen, Martina Rauner, Friedrich Stölzel, Lorenz C. Hofbauer, Tilman D. Rachner

المصدر: Breast Cancer Research, Vol 19, Iss 1, Pp 1-15 (2017)

مصطلحات موضوعية: mTOR inhibition, Breast cancer, Bone metastases, Hormone ablation, Antiresorptive, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13058-017-0885-7; https://doaj.org/toc/1465-542X

URL الوصول: https://doaj.org/article/444b18b9589b483c89b20d8fb31ffd36