نتائج البحث - "mTOR"

المؤلفون: Li, Jian-feng¹ (AUTHOR), Jin, Lei² (AUTHOR), Ma, Huan³ (AUTHOR), Suo, Jie⁴ (AUTHOR), Yang, Rui⁵ (AUTHOR), Yang, Xiao-ping⁵ (AUTHOR) xjshzdxyxp@163.com

المصدر: PLoS ONE. 12/5/2024, Vol. 19 Issue 12, p1-11. 11p.

مصطلحات موضوعية: *LABORATORY rats, *MTOR protein, *NEPHRITIS, *PROLIFERATING cell nuclear antigen, *CELL proliferation

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Academic Journal

松果菊苷调节mTOR/STAT3 信号通路对冠心病大鼠心肌细胞凋亡和炎症损伤的影响.

Alternate Title: Influences of echinacoside on myocardial cell apoptosis and inflammatory injury in rats with coronary heart disease by regulating mTOR/STAT3 signaling pathway.

المؤلفون: 苏强¹ suqing0911163@163.com, 谢家和¹ xiejiahezg@126.com, 黄鹤¹, 曾山¹, 钟一鸣¹

المصدر: Chinese Journal of Immunology. Dec2024, Vol. 40 Issue 12, p2574-2579. 6p.

مصطلحات موضوعية: *LABORATORY rats, *MTOR protein, *PYROPTOSIS, *CORONARY disease, *GENE expression

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Academic Journal

Protective Effects of Rosmarinic Acid and Epigallocatechin Gallate Against Doxorubicin-Induced Cytotoxicity and Genotoxicity in CHO-K1 Cells.

المؤلفون: HELVACIOĞLU, Sinem (AUTHOR), HAMİTOĞLU, Muhammed (AUTHOR), YILDIRIM, Ecem (AUTHOR), KORKUT, Şenay VURAL (AUTHOR), YABA, Aylin (AUTHOR), AYDIN, Ahmet (AUTHOR)

المصدر: Turkish Journal of Pharmaceutical Sciences. Dec2024, Vol. 21 Issue 6, p536-8. 8p.

مصطلحات موضوعية: *MTOR protein, *ROSMARINIC acid, *CYTOTOXINS, *REACTIVE oxygen species, *DNA damage, *EPIGALLOCATECHIN gallate, *GENETIC toxicology, *CHO cell

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10

Academic Journal

C118P Suppresses Gastric Cancer Growth via Promoting Autophagy–Lysosomal Degradation of RAB1A.

المؤلفون: Wei, Shihui¹ (AUTHOR), Zhang, Jing¹ (AUTHOR), Wu, Hai¹ (AUTHOR) wei_shihui@163.com, Liao, Zhengguang¹ (AUTHOR), Liu, Zhengrui¹ (AUTHOR), Hou, Yuhang¹ (AUTHOR), Du, Danyu¹ (AUTHOR), Jiang, Jingwei¹ (AUTHOR), Sun, Li¹ (AUTHOR), Yuan, Shengtao¹ (AUTHOR) yuanst@cpu.edu.cn, Yang, Mei¹ (AUTHOR) yuanst@cpu.edu.cn

المصدر: Pharmaceutics. Dec2024, Vol. 16 Issue 12, p1620. 20p.

مصطلحات موضوعية: *MTOR protein, *CELL cycle, *STOMACH cancer, *PROTEOLYSIS, *STAINS & staining (Microscopy), *AUTOPHAGY

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Academic Journal

Targeting mTOR Kinase with Natural Compounds: Potent ATP-Competitive Inhibition Through Enhanced Binding Mechanisms.

المؤلفون: Marafie, Sulaiman K.¹ (AUTHOR) sulaiman.marafie@dasmaninstitute.org, Alshawaf, Eman¹ (AUTHOR) eman.alshawaf@dasmaninstitute.org, Al-Mulla, Fahd² (AUTHOR) fahd.almulla@dasmaninstitute.org, Abubaker, Jehad¹ (AUTHOR) jehad.abubakr@dasmaninstitute.org, Mohammad, Anwar¹ (AUTHOR) jehad.abubakr@dasmaninstitute.org

المصدر: Pharmaceuticals (14248247). Dec2024, Vol. 17 Issue 12, p1677. 17p.

مصطلحات موضوعية: *MTOR inhibitors, *CHINESE medicine, *CATALYTIC domains, *DYNAMIC stability, *CELL physiology

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12

Academic Journal

mTOR Pathway Inhibition, Anticancer Activity and In Silico Calculations of Novel Hydrazone Derivatives in Two- and Three-Dimensional Cultured Type 1 Endometrial Cancer Cells.

المؤلفون: Bulbul, Muhammet Volkan^1,2 (AUTHOR) bkolbasi@medipol.edu.tr, Mermer, Arif^3,4,5 (AUTHOR) arif.mermer@sbu.edu.tr, Kolbasi, Bircan² (AUTHOR) semiha.kalender@medipol.edu.tr, Kocabas, Fatih⁶ (AUTHOR) faith.kocabas@yeditepe.edu.tr, Kalender, Semiha Mervenur² (AUTHOR), Kirectepe Aydin, Kiymet Asli⁷ (AUTHOR) asli.kirectepeaydin@nisantasi.edu.tr, Demircan, Turan⁸ (AUTHOR) turandemircan@mu.edu.tr, Keskin, İlknur² (AUTHOR) arif.mermer@sbu.edu.tr

المصدر: Pharmaceuticals (14248247). Dec2024, Vol. 17 Issue 12, p1562. 18p.

مصطلحات موضوعية: *MTOR protein, *ENDOMETRIAL cancer, *WESTERN immunoblotting, *HYDRAZONE derivatives, *MOLECULAR docking, *PROTEIN expression

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13

Academic Journal

BMAL1 and CLOCK proteins exhibit differential association with mitochondrial dynamics, protein synthesis pathways and muscle strength in human muscle.

المؤلفون: Figueroa‐Toledo, A. M.¹ (AUTHOR), Gutiérrez‐Pino, J.¹ (AUTHOR), Carriel‐Nesvara, A.¹ (AUTHOR), Marchese‐Bittencourt, M.¹ (AUTHOR), Zbinden‐Foncea, H.¹ (AUTHOR), Castro‐Sepúlveda, M.¹ (AUTHOR) mcastro@uft.cl

المصدر: Journal of Physiology. Dec2024, Vol. 602 Issue 23, p6403-6415. 13p.

مصطلحات موضوعية: *MITOCHONDRIAL dynamics, *MTOR protein, *MUSCLE proteins, *VASTUS lateralis, *SARCOPLASMIC reticulum

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Academic Journal

Multi-disciplinary team approach for pediatric hemimegalencephaly: Insights from a single institutional case series.

المؤلفون: Edmonds, Benjamin, Ngo, Jacqueline, Groves, Aran, Reyes, Beck, Gott, Rolanda, Chia, Dennis, Mirbaha, Hilda, Magaki, Shino, Khanlou, Negar, Pineles, Stacy, Salamon, Noriko, Thompson, Rachel, Newman, Maya, Rajaraman, Rajsekar, Hussain, Shaun, Fallah, Aria, Russell, Bianca, Nariai, Hiroki

المصدر: Epilepsia Open. 9(6)

مصطلحات موضوعية: MTOR, epilepsy, genetics, hemimegalencephaly (HME), multidisciplinary, Humans, Female, Male, Hemimegalencephaly, Patient Care Team, Child, Preschool, Infant, Child, Class I Phosphatidylinositol 3-Kinases, Hemispherectomy, Drug Resistant Epilepsy, TOR Serine-Threonine Kinases

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/14q042ct
https://escholarship.org/content/qt14q042ct/qt14q042ct.pdf

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Academic Journal

Anti‐b diminishes hyperlipidaemia and hepatic steatosis in hamsters and mice by suppressing the mTOR/PPARγ and mTOR/SREBP1 signalling pathways.

المؤلفون: Bian, Yu¹ (AUTHOR) bianyu@hrbmu.edu.cn, Wu, Han¹ (AUTHOR) wuhan@hrbmu.edu.cn, Jiang, Weitao¹ (AUTHOR), Kong, Xue¹ (AUTHOR), Xiong, Yuting¹ (AUTHOR), Zeng, Linghua¹ (AUTHOR), Zhang, Feng¹ (AUTHOR), Song, Jinglun¹ (AUTHOR), Wang, Chunlei¹ (AUTHOR), Yang, Yang¹ (AUTHOR), Zhang, Xinyue¹ (AUTHOR), Zhang, Yuning¹ (AUTHOR), Pang, Ping¹ (AUTHOR), Duo, Tianqi¹ (AUTHOR), Wang, Zhuo¹ (AUTHOR), Pan, Tengfei¹ (AUTHOR), Yang, Baofeng¹ (AUTHOR) yangbf@ems.hrbmu.edu.cn

المصدر: British Journal of Pharmacology. Nov2024, p1. 19p. 10 Illustrations.

مصطلحات موضوعية: *MTOR protein, *BLOOD lipids, *STAINS & staining (Microscopy), *FATTY liver, *METABOLIC disorders

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Academic Journal

DEPTOR attenuates asthma progression by suppressing endoplasmic reticulum stress through SOD1.

المؤلفون: Wang, Hao¹ (AUTHOR), Zhang, Lei² (AUTHOR), Shang, Yunxiao¹ (AUTHOR) shangyx52111@163.com

المصدر: Biology Direct. 11/12/2024, Vol. 19 Issue 1, p1-15. 15p.

مصطلحات موضوعية: *ENDOPLASMIC reticulum stress, *MTOR protein, *DENATURATION of proteins, *SUPEROXIDE dismutase, *PROTEIN expression

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Academic Journal

Prenatal mTOR Inhibitors in Tuberous Sclerosis Complex: Current Insights and Future Directions.

المؤلفون: Racioppi, Giacomo^1,2 (AUTHOR) giacomo.racioppi@opbg.net, Proietti Checchi, Martina³ (AUTHOR) martina.proietti@opbg.net, Sforza, Giorgia³ (AUTHOR) giorgia.sforza@opbg.net, Voci, Alessandra³ (AUTHOR) alessandra.voci@opbg.net, Mazzone, Luigi⁴ (AUTHOR) luigi.mazzone@uniroma2.it, Valeriani, Massimiliano^3,4,5 (AUTHOR) valeriani@opbg.net, Moavero, Romina^3,4 (AUTHOR) romina.moavero@opbg.net

المصدر: Journal of Clinical Medicine. Nov2024, Vol. 13 Issue 21, p6335. 12p.

مصطلحات موضوعية: *TUBEROUS sclerosis, *MTOR inhibitors, *FETAL development, *PREGNANT women, *HYDROPS fetalis

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Academic Journal

IL-32γ Induced Autophagy Through Suppression of MET and mTOR Pathways in Liver Tumor Growth Inhibition.

المؤلفون: Seo, Ji-Won¹ (AUTHOR) never1858@naver.com, Lee, Yong-Sun² (AUTHOR) kallintz123@korea.kr, Jeon, In-Sook¹ (AUTHOR) isjeon@chungbuk.ac.kr, Yu, Ji-Eun^3,4 (AUTHOR) jieunyu@mnu.ac.kr, Yoo, Jun-Sang¹ (AUTHOR) dbwnstkd8482@naver.com, Koo, Ja-Keun¹ (AUTHOR) pheej1@naver.com, Son, Dong-Ju¹ (AUTHOR) sondj1@chungbuk.ac.kr, Yoon, Jae-Suk¹ (AUTHOR) jyun@chungbuk.ac.kr, Han, Sang-Bae¹ (AUTHOR) shan@chungbuk.ac.kr, Yoon, Do-Young⁵ (AUTHOR) ydy4218@konkuk.ac.kr, Roh, Yoon-Seok¹ (AUTHOR) ysroh@chungbuk.ac.kr, Hong, Jin-Tae¹ (AUTHOR) jinthong@chungbuk.ac.kr, Shim, Jung-Hyun^3,4 (AUTHOR) jinthong@chungbuk.ac.kr

المصدر: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 21, p11678. 20p.

مصطلحات موضوعية: *MTOR protein, *LIVER tumors, *CELL cycle, *TUMOR growth, *LIVER cancer

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Academic Journal

Insights into the Therapeutic Potential of Active Ingredients of Citri Reticulatae Pericarpium in Combatting Sarcopenia: An In Silico Approach.

المؤلفون: Ullah, Amin¹ (AUTHOR), Bo, Yacong¹ (AUTHOR), Li, Jiangtao² (AUTHOR), Li, Jinjie² (AUTHOR), Khatun, Pipasha¹ (AUTHOR), Lyu, Quanjun¹ (AUTHOR) lqjnutr@zzu.edu.cn, Kou, Guangning^1,2 (AUTHOR) lqjnutr@zzu.edu.cn

المصدر: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 21, p11451. 22p.

مصطلحات موضوعية: *MTOR protein, *MOLECULAR dynamics, *MOLECULAR docking, *MUSCLE strength, *MUSCLE mass, *NETWORK hubs

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Academic Journal

Inhibitors of the mTOR signaling pathway can play an important role in breast cancer immunopathogenesis.

المؤلفون: Al‐Hawary, Sulieman I. Shelash¹ (AUTHOR), Altalbawy, Farag M. A.² (AUTHOR), Jasim, Saade Abdalkareem³ (AUTHOR) saade.a.j@uoa.edu.iq, Jyothi S, Renuka⁴ (AUTHOR), Jamal, Azfar^5,6 (AUTHOR) azfarjamal@mu.edu.sa, Naiyer, Mohammed M.⁷ (AUTHOR), Mahajan, Shriya⁸ (AUTHOR), Kalra, Hitesh⁹ (AUTHOR), Jawad, Mohammed Abed¹⁰ (AUTHOR), Zwamel, Ahmed Hussein^11,12,13 (AUTHOR)

المصدر: Cell Biology International. Nov2024, Vol. 48 Issue 11, p1601-1611. 11p.

مصطلحات موضوعية: *CANCER chemotherapy, *MTOR inhibitors, *BREAST cancer research, *BREAST cancer, *ANTINEOPLASTIC agents

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