-
1
المؤلفون: Michael B. Steele, James M Bogenberger, Oumar Barro, Mitesh J. Borad, Nathan Jenks, Mansi Arora, Bolni Marius Nagalo, Yumei Zhou, Lewis R. Roberts, Camilo Breton, Alexander T. Baker, Stephen J. Russell, Kah Whye Peng, Dan G. Duda
المصدر: Molecular Therapy Oncolytics
Molecular Therapy: Oncolytics, Vol 18, Iss, Pp 546-555 (2020)مصطلحات موضوعية: 0301 basic medicine, Cancer Research, viruses, PDAC, pancreatic ductal adenocarcinoma, pancreatic cancer, AST, aspartate aminotransferase, DMEM, Dulbecco’s modified Eagle’s medium, 0302 clinical medicine, PCR, polymerase chain reaction, G, glycoprotein G, Pharmacology (medical), MOI, multiplicity of infection, H, hemagglutinin, m, mouse, biology, hepatocellular carcinoma, ELISA, enzyme-linked immunosorbent assay, TCID50, 50% tissue culture infective dose, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, CBC, complete blood counts, Oncology, CPE, cytopathic effect, eGFP, enhanced green fluorescent protein, Vesicular stomatitis virus, 030220 oncology & carcinogenesis, Hepatocellular carcinoma, HBPC, hepatobiliary and pancreatic cancer, Molecular Medicine, wt, wild type, vesicular stomatitis virus, Genetically modified mouse, VSV, vesicular stomatitis virus, Hemagglutinin (influenza), F, fusion, lcsh:RC254-282, Article, hepatobiliary cancer, Measles virus, 03 medical and health sciences, h, human, Pancreatic cancer, ALT, alanine aminotransferase, medicine, DPBS, Dulbecco’s phosphate-buffered saline, IFN, interferon, HuCCT1, biliary tract cancer, CD46, oncolytic viral therapy, PE, phycoerythrin, biology.organism_classification, medicine.disease, HER-2, human epidermal growth factor receptor-2, MV, measles virus, Oncolytic virus, Ed-MV, Edmonston vaccine-strain measles virus, stomatognathic diseases, 030104 developmental biology, NIS, sodium iodide symporter, measles virus, biology.protein, Cancer research, ATCC, American Tissue Culture Collection, HCC, hepatocellular carcinoma
-
2
المؤلفون: Mark A. Sussman, Fareheh Firouzi
المصدر: EBioMedicine
EBioMedicine, Vol 58, Iss, Pp 102900-(2020)مصطلحات موضوعية: WT, wild type, Research paper, CSC, cardiac stem cell, EPOR, Erythropoietin receptor, LAD, Left anterior descending coronary artery, RIVA, Ang-1, Angiopoeitin 1, Clonal hematopoiesis of indeterminate pathology, Angiogenesis induction, MNC, Mononuclear cells, SH2B3, LNK [Src homology 2-B3 (SH2B3)] belongs to a family of SH2-containing proteins with important adaptor functions, Coronary bypass surgery, Profiling (information science), CABG, CHIP, Clonal hematopoiesis of indeterminate potential, PI3K, Phosphoinositide-3-Kinase, m, mouse, BM, Bone marrow, PPMC, Pearson Product Moment Correlation, CHIP, BrdU, Brome deoxyuridine, NR, non-responder, IGF-1, Insuline-like Growth Factor 1, AUC, Area under curve, BMMNC, Bone marrow mononuclear cell, General Medicine, KSL, mouse bone marrow stem cell subpopulation c-KIT+ Sca-I+ lin, EGF, Epidermal growth factor, GFP, Green fluorescent protein, Public Health and Health Services, MI, myocardial infarction, lcsh:Medicine (General), NGS, Next Generation Sequencing, medicine.medical_specialty, 2019-20 coronavirus outbreak, Clinical Sciences, 6MWT, 6-Minute Walk Test, InDel, mutation insertion or deletion variant, General Biochemistry, Genetics and Molecular Biology, CLARA, Clustering for Large Applications, PDFR, Platelet derived growth factor receptor, c-KIT/CD117, Stem Cell Factor Receptor c-KIT, CD117, HR, Hazard ratio, IGFBP, Insuline-like growth factor binding proteine, IHG, Analysis performed in accordance with ISHAGE guidelines, RFI, Reactome functional interaction, Machine learning, Humans, LAS, Longitudinal axis strain, Intensive care medicine, DE, Differential gene expression, Heart Failure, GWAS, Genome wide association study, CI, Confidence interval, hu, human, R, responder, lcsh:R, Myocardial regeneration, FACS, Fluorescence activated cell sorter, DNAseq, desoxyribonucleid acid sequencing, SNP, Single nucleotide polymorphism, variant, RT-PCR, Reverse transcriptase polymerase chain reaction, medicine.disease, Cardiac stem cell therapy, GMP, Good Manufacturing Practice, Post myocardial infarction heart failure, SDF-1, Stromal Cell-derived Factor 1, FDR, False discovery rate, PDGF, Platelet derived growth factor, EPO, Erythropoietin, MRI, Magnetic resonance imaging, VEGFR, Vascular Endothelial Growth Factor Receptor, AUR, Arch user repository, LCRC, Loss of cardiac regeneration capacity, GADPH, Glyceraldehyde 3 phosphate dehydrogenase, lcsh:Medicine, LVESD, Left Ventricular End Systolic Dimension, VCA, Virus-Capsid-Antigen, CEC, Circulating endothelial cells, CEC panel, CDs measured in PB, RNASeq, Ribonucleid acid sequencing, SUSAR, Suspected Unexpected Serious Adverse Reaction, GATA4, Transcriptional activator that binds to the consensus sequence 5′-AGATAG-3’, IL, Interleukin, Precision Medicine, CAP-EPC, Concentrated Ambient Particles – Endothelial Progenitor Cells, lcsh:R5-920, VEGF, Vascular Endothelial Growth Factor, SH2B3, STEMI, ST- segment Elevation Infarction, CD, Cluster of Differentiation, SCF, Stem Cell Factor, PBMNC, Peripheral blood mononuclear cell, CABG, Coronary Artery Bypass Graft, HSC, Hemopoeitic stem cell, ML, Machine learning, CFU, Colony-forming unit, PBMNC, mononuclear cells isolated from peripheral blood, LNK, SH2B adapter protein 3 (lymphocyte adapter protein), Coronavirus disease 2019 (COVID-19), BMSC, Bone marrow stem cells, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), LVEDV, Left Ventricular End Diastolic Volume, RWMS, Regional wall motion score, qPCR, Quantitative polymerase chain reaction, ROC, Receiver operating characteristics, CPC, cardiac progenitor cell, medicine, EGFR, Epidermal growth factor receptor, ICH GCP, Tripartite Guidelines Guideline for Good Clinical Practice, TiCoNE, Time course network enrichment, ELISA, Enzyme-Linked Immunosorbent Assay, PEI, Paul-Ehrlich Institute, LVEF, Left Ventricular Ejection Fraction, business.industry, HIF, Hypoxia-Inducible Factor, transcription factor, PB, Peripheral blood, EPC, Endothelial Progenitor Cells, EPC panel, CDs measured in PB, t-SNE, t-distributed stochastic neighbour embedding, ANCOVA, Analysis of covariance, WGCNA, Weighted gene coexpression network analysis, Heart failure, TNF, Tumor Necrosis Factor, PCR, Polymerase chain reaction, business
وصف الملف: application/pdf
-
3
المصدر: Pope, G R, Tilve, S, McArdle, C A, Lolait, S J & O'Carroll, A-M 2016, ' Agonist-induced internalization and desensitization of the apelin receptor ', Molecular and Cellular Endocrinology, vol. 437, pp. 108-119 . https://doi.org/10.1016/j.mce.2016.07.040
Molecular and Cellular Endocrinologyمصطلحات موضوعية: 0301 basic medicine, Time Factors, 030204 cardiovascular system & hematology, Biochemistry, Receptors, G-Protein-Coupled, Extracellular-signal-regulated kinase (ERK), 0302 clinical medicine, Endocrinology, DYN, dynamin, Phosphorylation, Extracellular Signal-Regulated MAP Kinases, Internalization, Receptor, m, mouse, media_common, Apelin Receptors, BIM, bisindolylmaleimide I, biology, DNM, dominant-negative mutant, APJ, apelin receptor, Endocytosis, NGS, normal goat serum, Apelin, Cell biology, Apelin receptor, eGFP, enhanced green fluorescent protein, PCSE, proportional cell surface expression, PTX, pertussis toxin, Intercellular Signaling Peptides and Proteins, CCV, clathrin coated vesicle, P70S6K, S6 ribosomal protein kinase, medicine.medical_specialty, media_common.quotation_subject, Signalling, CME, clathrin-mediated endocytosis, Clathrin, Article, GRK, G protein-coupled receptor kinase 2, 03 medical and health sciences, Internal medicine, U0126, 1,4-diamino-2,3-dicyano-1,4-bis[2-aminophenylthio] butadiene, medicine, Humans, G protein-coupled receptor, P, penicillin, Molecular Biology, Dynamin, Beta adrenergic receptor kinase, S, streptomycin, Signaling, Enzyme Activation, HEK293 Cells, 030104 developmental biology, biology.protein, FCS, fetal calf serum, Intracellular trafficking, βARR, β-arrestin1
وصف الملف: application/pdf
-
4
المؤلفون: Amanda B. Mackenzie, Sarah Hogg, Melanie J. Welham, Belinda A.N. Thompson, James Hewinson, Michael P. Storm
المصدر: Cellular Signalling
مصطلحات موضوعية: Patch-Clamp Techniques, Purinergic P2X Receptor Antagonists, Survival, Cell Survival, HEK293, human embryonic kidney 293, Cellular differentiation, Cell, Apoptosis, Biology, Article, Mice, 03 medical and health sciences, Adenosine Triphosphate, 0302 clinical medicine, Human Umbilical Vein Endothelial Cells, medicine, Animals, Humans, RNA, Small Interfering, Receptor, Cells, Cultured, Embryonic Stem Cells, Cell Proliferation, m, mouse, 030304 developmental biology, 0303 health sciences, Stem cell, Cell growth, HEK 293 cells, ES, embryonic stem, Cell Biology, Embryonic stem cell, 3. Good health, Cell biology, ATP, medicine.anatomical_structure, Gene Expression Regulation, P2X receptor, RNA Interference, Receptors, Purinergic P2X7, Signal transduction, Ion channel, 030217 neurology & neurosurgery, Signal Transduction
-
5
المؤلفون: Gabriella Nilsson Hall, Tim Herpelinck, Liesbet Geris, Luis Freitas Mendes, Ioannis Papantoniou, Niki Loverdou, Raphaëlle Lesage
المصدر: Advanced Drug Delivery Reviews
مصطلحات موضوعية: Computer science, DE, developmental engineering, Scale-up, Pharmaceutical Science, 02 engineering and technology, Biofabrication, ABG, autologous bone graft, Automation, PEG, poly(ethylene glycol), Pharmacology & Pharmacy, IN-VIVO, Biomanufacturing, MSC, mesenchymal stromal cell, 0303 health sciences, QbD, quality by Design, hUCB-BFs, human umbilical cord blood-borne fibroblasts, Bone implant, Clinical translation, Prostheses and Implants, 021001 nanoscience & nanotechnology, TCP, tricalcium phosphate, TE, tissue engineering, ECM, extracellular matrix, scRNA-seq, single cell RNA sequencing, Risk analysis (engineering), ATMP, Advanced Therapeutic Medicinal Product, SYSTEMS BIOLOGY, ADSC, adipose derived stem cells, mESC, mouse embryonic stem cells, CHyA, collagen hyaluronic acid, 0210 nano-technology, In silico tools, Life Sciences & Biomedicine, PDC (hPDC, mPDC), periosteum derived cell (h: human (m: mouse)), Omics, Article, Bone and Bones, MESENCHYMAL STEM-CELLS, CQA, critical quality attribute, 03 medical and health sciences, AC, articular chondrocytes, SINGLE-CELL, BM-MSC, bone marrow derived MSC, MATHEMATICAL-MODELS, CARTILAGE, Blueprint, Small animal, Animals, Humans, Tissue engineering, Computer Simulation, EO, endochondral ossification, Bone regeneration, 030304 developmental biology, Science & Technology, Scale (chemistry), PLGA, Poly Lactic-co-Glycolic Acid, Endochondral ossification, CoG, cost of goods, MARROW, STROMAL CELLS, TISSUE, CDM, cartilage-derived matrix, PCL, polycaprolactone, GMP, good manufacturing processes, Large animal
وصف الملف: Print-Electronic