نتائج البحث - "liver slices"

1

Academic Journal

Evaluating the antifibrotic potential of naringenin, asiatic acid, and icariin using murine and human precision‐cut liver slices

المؤلفون: Ke Luo, Yana Geng, Dorenda Oosterhuis, Vincent E. deMeijer, Peter Olinga

المصدر: Physiological Reports, Vol 12, Iss 21, Pp n/a-n/a (2024)

مصطلحات موضوعية: inflammation, liver fibrosis, natural products, precision‐cut liver slices, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-817X

URL الوصول: https://doaj.org/article/8f10d295a56a4da6913b78515ff2d49a

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2

Academic Journal

Metabolic Dysfunction-Associated Steatotic Liver Disease in a Dish:Human Precision-Cut Liver Slices as a Platform for Drug Screening and Interventions

المؤلفون: Li, Mei, Larsen, Frederik T., van den Heuvel, Marius C., Gier, Konstanze, Gorter, Alan R., Oosterhuis, Dorenda, Bijzet, Johan, de Meijer, Vincent E., Ravnskjaer, Kim, Nagelkerke, Anika, Olinga, Peter

المصدر: Li , M , Larsen , F T , van den Heuvel , M C , Gier , K , Gorter , A R , Oosterhuis , D , Bijzet , J , de Meijer , V E , Ravnskjaer , K , Nagelkerke , A & Olinga , P 2024 , ' Metabolic Dysfunction-Associated Steatotic Liver Disease in a Dish : Human Precision-Cut Liver Slices as a Platform for Drug Screening and Interventions ' , Nutrients , vol. 16 , no. 5 , 626 . https://doi.org/10.3390/nu16050626

مصطلحات موضوعية: hepatic steatosis, liver fibrosis, long-term incubation, metabolic dysfunction-associated steatotic liver disease (MASLD), non-alcoholic fatty liver disease (NAFLD), precision-cut liver slices (PCLSs)

وصف الملف: application/pdf

Relation: https://portal.findresearcher.sdu.dk/da/publications/c853c2c5-e937-4481-bc03-8da2c702880f

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/c853c2c5-e937-4481-bc03-8da2c702880f
https://doi.org/10.3390/nu16050626
https://findresearcher.sdu.dk/ws/files/258282485/nutrients-16-00626-v3.pdf

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3

Academic Journal

Modeling Nonalcoholic Fatty Liver Disease in the Dish Using Human-Specific Platforms: Strategies and LimitationsSummary

المؤلفون: Milad Rezvani, Ludovic Vallier, Adrien Guillot

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 5, Pp 1135-1145 (2023)

مصطلحات موضوعية: Induced Pluripotent Stem Cells, Liver-on-Chip, Precision-Cut Liver Slices, Liver Organoids, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X23000176; https://doaj.org/toc/2352-345X

URL الوصول: https://doaj.org/article/8962e23371844fbe83ced09e348924e5

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4

Academic Journal

Label-Free Imaging Techniques to Evaluate Metabolic Changes Caused by Toxic Liver Injury in PCLS

المؤلفون: Svetlana Rodimova, Artem Mozherov, Vadim Elagin, Maria Karabut, Ilya Shchechkin, Dmitry Kozlov, Dmitry Krylov, Alena Gavrina, Nikolai Bobrov, Vladimir Zagainov, Elena Zagaynova, Daria Kuznetsova

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9195

مصطلحات موضوعية: FLIM, precision-cut liver slices, toxic damage, liver pathology, metabolism

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms24119195

الاتاحة: https://doi.org/10.3390/ijms24119195

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5

Academic Journal

In Vitro Hepatic Models to Assess Herb–Drug Interactions: Approaches and Challenges

المؤلفون: Hlengwa N., Masilela C., Mtambo T. R., Sithole S., Naidoo S., Machaba K. E., Shabalala S. C., Ntamo Y., Dludla P. V., Milase R. N.

المصدر: Pharmaceuticals; Volume 16; Issue 3; Pages: 409

مصطلحات موضوعية: herb–drug interactions, hepatic models, human liver microsomes, S9 liver fractions, primary hepatocytes, precision liver slices, 3D culture, pharmacokinetics

وصف الملف: application/pdf

Relation: Natural Products; https://dx.doi.org/10.3390/ph16030409

الاتاحة: https://doi.org/10.3390/ph16030409

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6

Academic Journal

High precision-cut liver slice model to study cell-autonomous antiviral defense of hepatocytes within their microenvironment

المؤلفون: Marcus Brugger, Melanie Laschinger, Sandra Lampl, Annika Schneider, Katrin Manske, Dena Esfandyari, Norbert Hüser, Daniel Hartmann, Katja Steiger, Stefan Engelhardt, Dirk Wohlleber, Percy A. Knolle

المصدر: JHEP Reports, Vol 4, Iss 5, Pp 100465- (2022)

مصطلحات موضوعية: TNF-induced apoptosis, precision-cut liver slices, anti-viral immunity, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555922000374; https://doaj.org/toc/2589-5559

URL الوصول: https://doaj.org/article/d30298ff222c47149b68e90c4a9b5176

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7

Academic Journal

Distinct responses between healthy and cirrhotic human livers upon lipopolysaccharide challenge:possible implications for acute-on-chronic liver failure

المؤلفون: Suriguga, Su, Li, Mei, Luangmonkong, Theerut, Boersema, Miriam, de Jong, Koert P., Oosterhuis, Dorenda, Gorter, A. R., Beljaars, Leonie, Olinga, Peter

المصدر: Suriguga , S , Li , M , Luangmonkong , T , Boersema , M , de Jong , K P , Oosterhuis , D , Gorter , A R , Beljaars , L & Olinga , P 2022 , ' Distinct responses between healthy and cirrhotic human livers upon lipopolysaccharide challenge : possible implications for acute-on-chronic liver failure ' , American journal of physiology. Gastrointestinal and liver physiology , vol. 323 , no. 2 , pp. G114-G125 . https://doi.org/10.1152/ajpgi.00243.2021

مصطلحات موضوعية: acute-on-chronic liver failure, cirrhosis, human liver, lipopolysaccharide, precision-cut liver slices

وصف الملف: application/pdf

Relation: https://research.rug.nl/en/publications/29c698a9-8e72-4d01-9ae1-87fc6d931527

الاتاحة: https://hdl.handle.net/11370/29c698a9-8e72-4d01-9ae1-87fc6d931527
https://research.rug.nl/en/publications/29c698a9-8e72-4d01-9ae1-87fc6d931527
https://doi.org/10.1152/ajpgi.00243.2021
https://pure.rug.nl/ws/files/233861644/ajpgi.00243.2021.pdf

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8

Academic Journal

Disruption of vitamin A homeostasis by the biocide tetrakis(hydroxymethyl) phosphonium sulphate in pregnant rabbits

المؤلفون: Estrada-Ortiz, Natalia, Starokozhko, Viktoriia, van Steenwijk, Hidde, van der Heide, Cor, Permentier, Hjalmar, van Heemskerk, Lisanne, Prins, Grietje Harmanna, Heegsma, Janette, Faber, Klaas Nico, Bressers, Steffi, Steiblen, Guy, de Groot, Antoinette, Groome, Steve, van Miert, Erik, Groothuis, Geny, de Graaf, Inge Anne Maria

المصدر: Estrada-Ortiz , N , Starokozhko , V , van Steenwijk , H , van der Heide , C , Permentier , H , van Heemskerk , L , Prins , G H , Heegsma , J , Faber , K N , Bressers , S , Steiblen , G , de Groot , A , Groome , S , van Miert , E , Groothuis , G & de Graaf , I A M 2022 , ' Disruption of vitamin A homeostasis by the biocide tetrakis(hydroxymethyl) phosphonium sulphate in pregnant rabbits ' , Journal of Applied Toxicology , vol. ....

مصطلحات موضوعية: precision-cut liver slices, retinoid binding proteins, retinoids, teratogenicity, tetrakis(hydroxymethyl) phosphonium sulphate, THPS, VAD, vitamin A homeostasis, ACUTE-PHASE RESPONSE, RETINOL-BINDING-PROTEIN, PRECISION-CUT LIVER, ACID, METABOLISM, EXPRESSION, SECRETION, ALCOHOL, EMBRYO, ESTERS

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/63ac7ca1-b00a-4740-b417-b6c37a1184fe
https://research.rug.nl/en/publications/63ac7ca1-b00a-4740-b417-b6c37a1184fe
https://doi.org/10.1002/jat.4364
https://pure.rug.nl/ws/files/238493648/J_of_Applied_Toxicology_2022_Estrada_Ortiz_Disruption_of_vitamin_A_homeostasis_by_the_biocide_tetrakis_hydroxymethyl_.pdf

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9

Academic Journal

Supplementary data of distinct responses between healthy and cirrhotic human livers upon LPS challenge: possible implications for ACLF

المؤلفون: Su Suriguga (11097987)

مصطلحات موضوعية: Gastroenterology and Hepatology, acute-on-chronic liver failure (ACLF), cirrhotic liver tissue, precision-cut liver slices, Lipopolysaccharide

Relation: https://figshare.com/articles/online_resource/Supplementary_data_of_distinct_responses_between_healthy_and_cirrhotic_human_livers_upon_LPS_challenge_possible_implications_for_ACLF/14932527

الاتاحة: https://doi.org/10.6084/m9.figshare.14932527.v1

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10

Academic Journal

Differentiation of Heterogeneous Mouse Liver from HCC by Hyperpolarized 13C Magnetic Resonance

المؤلفون: Naama Lev-Cohain, Gal Sapir, Sivaranjan Uppala, Atara Nardi-Schreiber, Shraga Goldberg, Yael Adler-Levy, Jacob Sosna, J. Gomori, Rachel Katz-Brull

المصدر: Sci; Volume 3; Issue 1; Pages: 8

مصطلحات موضوعية: lactate dehydrogenase, alanine transaminase, MDR2 knockout, dissolution dynamic nuclear polarization, perfused precision cut liver slices

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/sci3010008

الاتاحة: https://doi.org/10.3390/sci3010008

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11

Academic Journal

Novel defatting strategies reduce lipid accumulation in primary human culture models of liver steatosis

المؤلفون: Lynda Aoudjehane, Jérémie Gautheron, Wilfried Le Goff, Claire Goumard, Julia Gilaizeau, Chan Sonavine Nget, Eric Savier, Muhammad Atif, Philippe Lesnik, Romain Morichon, Yves Chrétien, Yvon Calmus, Olivier Scatton, Chantal Housset, Filomena Conti

المصدر: Disease Models & Mechanisms, Vol 13, Iss 4 (2020)

مصطلحات موضوعية: defatting, human hepatocytes, human precision-cut liver slices, liver transplantation, steatosis, triglycerides, Medicine, Pathology, RB1-214

وصف الملف: electronic resource

Relation: http://dmm.biologists.org/content/13/4/dmm042663; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

URL الوصول: https://doaj.org/article/eff1e63a2c874e1f9e36d2804419bb84

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12

Dynamic Protective Potential of Couroupita guianensis. Aubl against Reactive Free Radicals: An Approach of Stimulated in vitro model.

المؤلفون: DHANDAPANI, KAVITHA

المساهمون: Nil

المصدر: Indian Journal of Traditional Knowledge (IJTK); Vol 23, No 5 (2024): Indian Journal of Traditional Knowledge; 441-451

مصطلحات موضوعية: Antioxidant, Couroupita guianensis.Aubl., free radicals, goat liver slices, in vitro model

وصف الملف: application/pdf

الاتاحة: http://op.niscair.res.in/index.php/IJTK/article/view/45325
https://doi.org/10.56042/ijtk.v23i5.45325

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13

Academic Journal

Glutathione-responsive cyclodextrin-nanosponges as drug delivery systems for doxorubicin:Evaluation of toxicity and transport mechanisms in the liver

المؤلفون: Daga, Martina, de Graaf, Inge A M, Argenziano, Monica, Barranco, Ana Sofia Martinez, Loeck, Maximillian, Al-Adwi, Yehya, Cucci, Marie Angele, Caldera, Fabrizio, Trotta, Francesco, Barrera, Giuseppina, Casini, Angela, Cavalli, Roberta, Pizzimenti, Stefania

المصدر: Daga , M , de Graaf , I A M , Argenziano , M , Barranco , A S M , Loeck , M , Al-Adwi , Y , Cucci , M A , Caldera , F , Trotta , F , Barrera , G , Casini , A , Cavalli , R & Pizzimenti , S 2020 , ' Glutathione-responsive cyclodextrin-nanosponges as drug delivery systems for doxorubicin : Evaluation of toxicity and transport mechanisms in the liver ' , Toxicology in Vitro , vol. 65 , 104800 . https://doi.org/10.1016/j.tiv.2020.104800

مصطلحات موضوعية: Glutathione-responsive nanosponges, beta-Cyclodextrin, Doxorubicin, HepG2 cells, Rat precision-cut liver slices, Hepatotoxicity, IN-VITRO, CANCER-CELLS, NANOPARTICLES, METABOLISM, SLICES, TOOL, DIFFUSION, MODEL, VIVO, PH

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/090ad893-7bf6-4143-b770-bb6005b12bc4
https://research.rug.nl/en/publications/090ad893-7bf6-4143-b770-bb6005b12bc4
https://doi.org/10.1016/j.tiv.2020.104800
https://pure.rug.nl/ws/files/127130002/1_s2.0_S0887233319308860_main.pdf

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14

Academic Journal

Inhibition of tyrosine kinase receptor signaling attenuates fibrogenesis in an ex vivo model of human renal fibrosis

المؤلفون: Bigaeva, Emilia, Stribos, Elisabeth G. D., Mutsaers, Henricus A. M., Piersma, Bram, Leliveld, Anna M., de Jong, Igle J., Bank, Ruud A., Seelen, Marc A., van Goor, Harry, Wollin, Lutz, Olinga, Peter, Boersema, Miriam

المصدر: Bigaeva , E , Stribos , E G D , Mutsaers , H A M , Piersma , B , Leliveld , A M , de Jong , I J , Bank , R A , Seelen , M A , van Goor , H , Wollin , L , Olinga , P & Boersema , M 2020 , ' Inhibition of tyrosine kinase receptor signaling attenuates fibrogenesis in an ex vivo model of human renal fibrosis ' , American journal of physiology-Renal physiology , vol. 318 , no. 1 , pp. F117-F134 . https://doi.org/10.1152/ajprenal.00108.2019

مصطلحات موضوعية: nintedanib, precision-cut kidney slices, renal fibrosis, tyrosine kinase receptor, CUT KIDNEY SLICES, GROWTH-FACTOR, ANGIOKINASE INHIBITOR, LIVER SLICES, CELL CANCER, EARLY-ONSET, BIBF 1120, EXPRESSION, ANGIOGENESIS

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/d559f867-9a02-4f05-94f4-9945138495be
https://research.rug.nl/en/publications/d559f867-9a02-4f05-94f4-9945138495be
https://doi.org/10.1152/ajprenal.00108.2019
https://pure.rug.nl/ws/files/103301347/ajprenal.00108.2019.pdf

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15

Academic Journal

Host microbiota dictates the proinflammatory impact of LPS in the murine liver

المؤلفون: Suriguga, Su, Luangmonkong, Theerut, Mutsaers, Henricus A. M., Groothuis, Geny M. M., Olinga, Peter

المصدر: Suriguga , S , Luangmonkong , T , Mutsaers , H A M , Groothuis , G M M & Olinga , P 2020 , ' Host microbiota dictates the proinflammatory impact of LPS in the murine liver ' , Toxicology in Vitro , vol. 67 , 104920 . https://doi.org/10.1016/j.tiv.2020.104920

مصطلحات موضوعية: Germ free mice, Microbiota, Liver, Precision-cut liver slices, LPS, INCREASED INTESTINAL PERMEABILITY, PRECISION-CUT LIVER, GERM-FREE, IRAK-M, TRANSCRIPTIONAL REGULATION, IMMUNE-RESPONSE, INNATE IMMUNITY, TNF-ALPHA, MICE, INFLAMMATION

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/2ce5495f-72f1-4038-a558-0a9761190232
https://research.rug.nl/en/publications/2ce5495f-72f1-4038-a558-0a9761190232
https://doi.org/10.1016/j.tiv.2020.104920
https://pure.rug.nl/ws/files/133408018/1_s2.0_S0887233320304707_main.pdf

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16

Academic Journal

Modified culture protocol for testing anti-fibrotic drugs using precision-cut liver slices

المؤلفون: Luangmonkong, Theerut, Olinga, Peter

المصدر: Luangmonkong , T & Olinga , P 2020 , ' Modified culture protocol for testing anti-fibrotic drugs using precision-cut liver slices ' , Pharmaceutical Sciences Asia , vol. 47 , no. 3 , pp. 301-309 . https://doi.org/10.29090/psa.2020.03.019.0137

مصطلحات موضوعية: Anti-fibrotic, Culture method, Culture protocol, LY2109761, Precision-cut liver slices

وصف الملف: application/pdf

Relation: https://research.rug.nl/en/publications/27f5333f-f5e0-4a0c-953a-c79e55dd2268

الاتاحة: https://hdl.handle.net/11370/27f5333f-f5e0-4a0c-953a-c79e55dd2268
https://research.rug.nl/en/publications/27f5333f-f5e0-4a0c-953a-c79e55dd2268
https://doi.org/10.29090/psa.2020.03.019.0137
https://pure.rug.nl/ws/files/174437232/2020_47_3_301_309.pdf
http://www.scopus.com/inward/record.url?scp=85088697205&partnerID=8YFLogxK

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