-
1Academic Journal
المؤلفون: Jingwei Hou, Bo Hou, Gongpeng He
المصدر: ISPRS International Journal of Geo-Information, Vol 13, Iss 11, p 384 (2024)
مصطلحات موضوعية: key determinant, spatiotemporal heterogeneity, urban resilience, Theil index, geodetector, Geography (General), G1-922
وصف الملف: electronic resource
-
2Academic Journal
المؤلفون: Junkai Yin, Kaijie Wu, Yun Yu, Yuan Zhong, Zihua Song, Chao Chang, Guozhi Liu
مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, Physical Sciences not elsewhere classified, strand breaks caused, molecular dynamics simulation, key determinant crucial, 33 thz waves, frequency filtering experiments, inhibiting telomerase activity, 4t1 cells irradiated, thz modulation, telomerase activity, optimized frequency, experiments showed, vivo <, vitro <, undergo aging, two kinds, term suppression, telomere crisis, telomerase inhibitors, study demonstrates, stabilize chromosomes, seriously affected
-
3Academic Journal
المؤلفون: Miguel de la Puente, Damien Laage
مصطلحات موضوعية: Biophysics, Biochemistry, Biotechnology, Ecology, Space Science, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, many fundamental questions, based molecular simulations, water microdroplets used, core becomes enriched, acidity depends strongly, pure water systems, atmospheric aqueous aerosols, atmospheric aerosols, aqueous microdroplets, water droplets, volume ratio, sizes ranging, results obtained, remained elusive, key determinant, ion concentrations, important implications, hydroxide ions, hydroxide anions, chemical reactivity, bulk solutions, analytic model, acidity differs
-
4Academic Journal
المؤلفون: Qiqi Zhang, Xuan Wang, Yuanyuan Zhao, Zhuo Cheng, De Fang, Yingqi Liu, Gan Tian, Menghuan Li, Zhong Luo
مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Cancer, Computational Biology, Chemical Sciences not elsewhere classified, shown significant implications, intrinsic lipid metabolism, elevated ros stress, cooperative ferroptosis immunotherapy, vital membrane structures, robust tumor regression, immunosuppressive tumor microenvironment, overexpressing tumor cells, ldr immunotherapeutic effects, tumor cells, membrane lipids, immunostimulatory effects, antitumor effects, tme ), study offers, situ reprogramming, peroxidation susceptibility, nanointegrated strategy, key determinant, inhibiting sirnas
-
5Academic Journal
مصطلحات موضوعية: Cell Biology, Molecular Biology, Sociology, Science Policy, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, therapeutic relationship contributed, qualitative research focused, patients &# 8217, four superordinate themes, idiosyncratic change processes, effective psychological interventions, crucial change enabler, centred care provision, psychological change, primary care, change enablers, structured interviews, results identified, remote delivery, practical implications, personal commitment, nine semi, key determinant, ipa ), intervention features, inform development, gps emerged, existing literature, barriers associated
-
6Academic Journal
مصطلحات موضوعية: Cell Biology, Molecular Biology, Sociology, Science Policy, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, therapeutic relationship contributed, qualitative research focused, patients &# 8217, four superordinate themes, idiosyncratic change processes, effective psychological interventions, crucial change enabler, centred care provision, psychological change, primary care, change enablers, structured interviews, results identified, remote delivery, practical implications, personal commitment, nine semi, key determinant, ipa ), intervention features, inform development, gps emerged, existing literature, barriers associated
-
7Academic Journal
مصطلحات موضوعية: Cell Biology, Molecular Biology, Sociology, Science Policy, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, therapeutic relationship contributed, qualitative research focused, patients &# 8217, four superordinate themes, idiosyncratic change processes, effective psychological interventions, crucial change enabler, centred care provision, psychological change, primary care, change enablers, structured interviews, results identified, remote delivery, practical implications, personal commitment, nine semi, key determinant, ipa ), intervention features, inform development, gps emerged, existing literature, barriers associated
-
8Academic Journal
مصطلحات موضوعية: Cell Biology, Molecular Biology, Sociology, Science Policy, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, therapeutic relationship contributed, qualitative research focused, patients &# 8217, four superordinate themes, idiosyncratic change processes, effective psychological interventions, crucial change enabler, centred care provision, psychological change, primary care, change enablers, structured interviews, results identified, remote delivery, practical implications, personal commitment, nine semi, key determinant, ipa ), intervention features, inform development, gps emerged, existing literature, barriers associated
-
9Academic Journal
مصطلحات موضوعية: Cell Biology, Molecular Biology, Sociology, Science Policy, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, therapeutic relationship contributed, qualitative research focused, patients &# 8217, four superordinate themes, idiosyncratic change processes, effective psychological interventions, crucial change enabler, centred care provision, psychological change, primary care, change enablers, structured interviews, results identified, remote delivery, practical implications, personal commitment, nine semi, key determinant, ipa ), intervention features, inform development, gps emerged, existing literature, barriers associated
-
10Academic Journal
المؤلفون: Guillaume Butler-Laporte, Gundula Povysil, Jack A. Kosmicki, Elizabeth T. Cirulli, Theodore Drivas, Simone Furini, Chadi Saad, Axel Schmidt, Pawel Olszewski, Urszula Korotko, Mathieu Quinodoz, Elifnaz Çelik, Kousik Kundu, Klaudia Walter, Junghyun Jung, Amy D. Stockwell, Laura G. Sloofman, Daniel M. Jordan, Ryan C. Thompson, Diane Del Valle, Nicole Simons, Esther Cheng, Robert Sebra, Eric E. Schadt, Seunghee Kim-Schulze, Sacha Gnjatic, Miriam Merad, Joseph D. Buxbaum, Noam D. Beckmann, Alexander W. Charney, Bartlomiej Przychodzen, Timothy Chang, Tess D. Pottinger, Ning Shang, Fabian Brand, Francesca Fava, Francesca Mari, Karolina Chwialkowska, Magdalena Niemira, Szymon Pula, J Kenneth Baillie, Alex Stuckey, Antonio Salas, Xabier Bello, Jacobo Pardo-Seco, Alberto Gómez-Carballa, Irene Rivero-Calle, Federico Martinón-Torres, Andrea Ganna, Konrad J. Karczewski, Kumar Veerapen, Mathieu Bourgey, Guillaume Bourque, Robert JM Eveleigh, Vincenzo Forgetta, David Morrison, David Langlais, Mark Lathrop, Vincent Mooser, Tomoko Nakanishi, Robert Frithiof, Michael Hultström, Miklos Lipcsey, Yanara Marincevic-Zuniga, Jessica Nordlund, Kelly M. Schiabor Barrett, William Lee, Alexandre Bolze, Simon White, Stephen Riffle, Francisco Tanudjaja, Efren Sandoval, Iva Neveux, Shaun Dabe, Nicolas Casadei, Susanne Motameny, Manal Alaamery, Salam Massadeh, Nora Aljawini, Mansour S. Almutairi, Yaseen M. Arabi, Saleh A. Alqahtani, Fawz S. Al Harthi, Amal Almutairi, Fatima Alqubaishi, Sarah Alotaibi, Albandari Binowayn, Ebtehal A. Alsolm, Hadeel El Bardisy, Mohammad Fawzy, Fang Cai, Nicole Soranzo, Adam Butterworth, COVID-19 Host Genetics Initiative, DeCOI Host Genetics Group, GEN-COVID Multicenter Study (Italy), Sergio Daga, Ilaria Meloni, Mount Sinai Clinical Intelligence Center, GEN-COVID consortium (Spain), GenOMICC Consortium, Japan COVID-19 Task Force, Regeneron Genetics Center, Daniel H. Geschwind, Stephanie Arteaga, Alexis Stephens, Manish J. Butte, Paul C. Boutros, Takafumi N. Yamaguchi, Shu Tao, Stefan Eng, Timothy Sanders, Paul J. Tung, Michael E. Broudy, Yu Pan, Alfredo Gonzalez, Nikhil Chavan, Ruth Johnson, Bogdan Pasaniuc, Brian Yaspan, Sandra Smieszek, Carlo Rivolta, Stephanie Bibert, Pierre-Yves Bochud, Maciej Dabrowski, Pawel Zawadzki, Mateusz Sypniewski, Elżbieta Kaja, Pajaree Chariyavilaskul, Voraphoj Nilaratanakul, Nattiya Hirankarn, Vorasuk Shotelersuk, Monnat Pongpanich, Chureerat Phokaew, Wanna Chetruengchai, Katsushi Tokunaga, Masaya Sugiyama, Yosuke Kawai, Takanori Hasegawa, Tatsuhiko Naito, Ho Namkoong, Ryuya Edahiro, Akinori Kimura, Seishi Ogawa, Takanori Kanai, Koichi Fukunaga, Yukinori Okada, Seiya Imoto, Satoru Miyano, Serghei Mangul, Malak S. Abedalthagafi, Hugo Zeberg, Joseph J. Grzymski, Nicole L. Washington, Stephan Ossowski, Kerstin U. Ludwig, Eva C. Schulte, Olaf Riess, Marcin Moniuszko, Miroslaw Kwasniewski, Hamdi Mbarek, Said I. Ismail, Anurag Verma, David B. Goldstein, Krzysztof Kiryluk, Alessandra Renieri, Manuel A. R. Ferreira, J Brent Richards
المساهمون: Butler-Laporte, Guillaume, Povysil, Gundula, Kosmicki, Jack A., Cirulli, Elizabeth T., Drivas, Theodore, Furini, Simone, Saad, Chadi, Schmidt, Axel, Olszewski, Pawel, Korotko, Urszula, Quinodoz, Mathieu, Çelik, Elifnaz, Kundu, Kousik, Walter, Klaudia, Jung, Junghyun, Stockwell, Amy D., Sloofman, Laura G., Jordan, Daniel M., Thompson, Ryan C., Del Valle, Diane, Simons, Nicole, Cheng, Esther, Sebra, Robert, Schadt, Eric E., Kim-Schulze, Seunghee, Gnjatic, Sacha, Merad, Miriam, Buxbaum, Joseph D., Beckmann, Noam D., Charney, Alexander W., Przychodzen, Bartlomiej, Chang, Timothy, Pottinger, Tess D., Shang, Ning, Brand, Fabian, Fava, Francesca, Mari, Francesca, Chwialkowska, Karolina, Niemira, Magdalena, Pula, Szymon, Kenneth Baillie, J, Stuckey, Alex, Salas, Antonio, Bello, Xabier, Pardo-Seco, Jacobo, Gómez-Carballa, Alberto, Rivero-Calle, Irene, Martinón-Torres, Federico, Ganna, Andrea, Karczewski, Konrad J., Veerapen, Kumar, Bourgey, Mathieu, Bourque, Guillaume, JM Eveleigh, Robert, Forgetta, Vincenzo, Morrison, David, Langlais, David, Lathrop, Mark, Mooser, Vincent, Nakanishi, Tomoko, Frithiof, Robert, Hultström, Michael, Lipcsey, Miklo, Marincevic-Zuniga, Yanara, Nordlund, Jessica, Schiabor Barrett, Kelly M., Lee, William, Bolze, Alexandre, White, Simon, Riffle, Stephen, Tanudjaja, Francisco, Sandoval, Efren, Neveux, Iva, Dabe, Shaun, Casadei, Nicola, Motameny, Susanne, Alaamery, Manal, Massadeh, Salam, Aljawini, Nora, Almutairi, Mansour S., Arabi, Yaseen M., Alqahtani, Saleh A., Al Harthi, Fawz S., Almutairi, Amal, Alqubaishi, Fatima, Alotaibi, Sarah, Binowayn, Albandari, Alsolm, Ebtehal A., El Bardisy, Hadeel, Fawzy, Mohammad, Cai, Fang, Soranzo, Nicole, Butterworth, Adam, Host Genetics Initiative, COVID-19, Host Genetics Group, Decoi, Multicenter Study (Italy), GEN-COVID, Daga, Sergio, Meloni, Ilaria, Sinai Clinical Intelligence Center, Mount, consortium (Spain), GEN-COVID
مصطلحات موضوعية: Host genetics is a key determinant of COVID-19 outcomes. Previously, the COVID-19 Host Genetics Initiative genome-wide association study used common variants to identify multiple loci associated with COVID-19 outcomes. However, variants with the largest impact on COVID-19 outcomes are expected to be rare in the population. Hence, studying rare variants may provide additional insights into disease susceptibility and pathogenesis, thereby informing therapeutics development. Here, we combined whole-exome and whole-genome sequencing from 21 cohorts across 12 countries and performed rare variant exome-wide burden analyses for COVID-19 outcomes. In an analysis of 5,085 severe disease cases and 571,737 controls, we observed that carrying a rare deleterious variant in the SARS-CoV-2 sensor toll-like receptor TLR7 (on chromosome X) was associated with a 5.3-fold increase in severe disease (95% CI: 2.75-10.05, p = 5.41x10-7). This association was consistent across sexes. These results further support TLR7 as a genetic determinant of severe disease and suggest that larger studies on rare variants influencing COVID-19 outcomes could provide additional insights
وصف الملف: ELETTRONICO
Relation: info:eu-repo/semantics/altIdentifier/pmid/36327219; info:eu-repo/semantics/altIdentifier/wos/WOS:000925085700002; volume:18; issue:11; journal:PLOS GENETICS; https://hdl.handle.net/11365/1220661; https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010367; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632827/
-
11Academic Journal
المؤلفون: Attila Taborosi (4950244), Qiyuan He (1439968), Yusuke Ano (1583398), Naoto Chatani (1364754), Seiji Mori (365352)
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Sociology, Inorganic Chemistry, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, density functional theory, aminoquinolinyl aromatic amides, reaction path determination, nh amide proton, )- catalyzed reaction, reaction path, reaction proceeds, )- complex, turnover frequency, rh (, rh catalyst, reductive elimination, oxidative addition, oxidation number, ortho position, n <, migratory insertion, key determinant, following steps, determining intermediate, also found
-
12Academic Journal
المؤلفون: Gail Moloney (689225), Michael Sutherland (2904743), Leah Upcroft (12003837), Rachel Clark (790098), Parul Punjabi-Jagdish (12003840), Suzanne Rienks (12003843), Alison Bowling (12003846), Iain Walker (6031304)
مصطلحات موضوعية: Microbiology, Cell Biology, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Science Policy, Infectious Diseases, role community plays, large public hospital, registered organ donors, respectful dialogic interaction, negative beliefs decreased,
+registering%22">xlink "> registering, immediate registration opportunity, register participants registered, %22">xlink ">, immediate opportunity, negative beliefs, spot opportunity, organ donation, tissues essential, respectful non, proselytizing dialogue, positive beliefs, negatively correlated, measured positive, key determinant, judgmental interaction, four days -
13Academic Journal
المؤلفون: Jianzhuang Zheng, Lingyan Huang
المصدر: Sustainability, Vol 14, Iss 7242, p 7242 (2022)
مصطلحات موضوعية: rural homestay inn, spatiotemporal pattern, key determinant, hotspot detection, Zhejiang Province, China, Environmental effects of industries and plants, TD194-195, Renewable energy sources, TJ807-830, Environmental sciences, GE1-350
Relation: https://www.mdpi.com/2071-1050/14/12/7242; https://doaj.org/toc/2071-1050; https://doaj.org/article/be1356223d9a4906bcf32d938dfbe24c
-
14Academic Journal
المؤلفون: S. N. Kukushkin
المصدر: Вестник Российского экономического университета имени Г. В. Плеханова, Vol 0, Iss 2, Pp 130-141 (2019)
مصطلحات موضوعية: knowledge index of regions, federal district, economy of knowledge, the world bank, global economic crisis – great recession, key determinant of the matrix, economic and social indicators, rating, assessment methodology, Economics as a science, HB71-74
وصف الملف: electronic resource
-
15Academic Journal
المؤلفون: Casey Folks (11614843), Uttam Sharma Phuyal (11614846), Mahima Rajesh (11614849), Nagathushara Arja (11614852), Michael Gladden (11614855), Logan Hamm (11614858), Agampodi Swarnapali De Silva Indrasekara (11614861)
مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Pharmacology, Biotechnology, Virology, Space Science, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, significantly less aggregation, particle scattering spectra, optimal analytical performance, foundational design parameters, enhanced raman spectroscopy, comparative quantitative analysis, extraordinary optical properties, sers detection efficiency, stronger chemical interactions, many fabrication parameters, polymer physical characteristics, polymer matrix porosity, optical platforms plasmonic, predictable optical properties, key fabrication parameters, optical properties, chemical interactions, polymer matrix, optical platform, key determinant, field spectroscopy
-
16Image
المؤلفون: Yuqi Zhou, Julie Jadlowsky, Caitlin Baiduc, Alex W. Klattenhoff, Zhilin Chen, Alan D. Bennett, Nicholas J. Pumphrey, Bent K. Jakobsen, James L. Riley
مصطلحات موضوعية: Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Statistics, Infectious Diseases, Virology, activate caspase 3, three distinct hiv, previously optimized hiv, augment hiv control,
+engineered%22">xlink "> engineered, tcr affinity enhancement, cells remained superior, control hiv replication, hiv replication, target hiv, killed hiv, hiv activity, whether engineered, time course, target recognition, studies suggest, presenting cells, key determinant, infected targets, generated engineered, gain insight, functional capabilities -
17Image
المؤلفون: Yuqi Zhou, Julie Jadlowsky, Caitlin Baiduc, Alex W. Klattenhoff, Zhilin Chen, Alan D. Bennett, Nicholas J. Pumphrey, Bent K. Jakobsen, James L. Riley
مصطلحات موضوعية: Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Statistics, Infectious Diseases, Virology, activate caspase 3, three distinct hiv, previously optimized hiv, augment hiv control,
+engineered%22">xlink "> engineered, tcr affinity enhancement, cells remained superior, control hiv replication, hiv replication, target hiv, killed hiv, hiv activity, whether engineered, time course, target recognition, studies suggest, presenting cells, key determinant, infected targets, generated engineered, gain insight, functional capabilities -
18Image
المؤلفون: Yuqi Zhou, Julie Jadlowsky, Caitlin Baiduc, Alex W. Klattenhoff, Zhilin Chen, Alan D. Bennett, Nicholas J. Pumphrey, Bent K. Jakobsen, James L. Riley
مصطلحات موضوعية: Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Statistics, Infectious Diseases, Virology, activate caspase 3, three distinct hiv, previously optimized hiv, augment hiv control,
+engineered%22">xlink "> engineered, tcr affinity enhancement, cells remained superior, control hiv replication, hiv replication, target hiv, killed hiv, hiv activity, whether engineered, time course, target recognition, studies suggest, presenting cells, key determinant, infected targets, generated engineered, gain insight, functional capabilities -
19Image
المؤلفون: Yuqi Zhou, Julie Jadlowsky, Caitlin Baiduc, Alex W. Klattenhoff, Zhilin Chen, Alan D. Bennett, Nicholas J. Pumphrey, Bent K. Jakobsen, James L. Riley
مصطلحات موضوعية: Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Statistics, Infectious Diseases, Virology, activate caspase 3, three distinct hiv, previously optimized hiv, augment hiv control,
+engineered%22">xlink "> engineered, tcr affinity enhancement, cells remained superior, control hiv replication, hiv replication, target hiv, killed hiv, hiv activity, whether engineered, time course, target recognition, studies suggest, presenting cells, key determinant, infected targets, generated engineered, gain insight, functional capabilities -
20Image
المؤلفون: Yuqi Zhou, Julie Jadlowsky, Caitlin Baiduc, Alex W. Klattenhoff, Zhilin Chen, Alan D. Bennett, Nicholas J. Pumphrey, Bent K. Jakobsen, James L. Riley
مصطلحات موضوعية: Microbiology, Cell Biology, Biotechnology, Immunology, Cancer, Statistics, Infectious Diseases, Virology, activate caspase 3, three distinct hiv, previously optimized hiv, augment hiv control,
+engineered%22">xlink "> engineered, tcr affinity enhancement, cells remained superior, control hiv replication, hiv replication, target hiv, killed hiv, hiv activity, whether engineered, time course, target recognition, studies suggest, presenting cells, key determinant, infected targets, generated engineered, gain insight, functional capabilities
Full Text Finder