المؤلفون: Alberto Ceccon (1746361), Vitali Tugarinov (1338960), G. Marius Clore (237616)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Pharmacology, Computational Biology, Chemical Sciences not elsewhere classified, polyglutamine tract, 16- residue N-terminal amphiphilic ., 1 Q 35, htt, intracellular proline-binding domain, P 2 L 2, PL, sub-millisecond time scale, SH 3 increases, unliganded P 2 dimer, Fyn SH 3, concentration-dependent exchange-in., NT, P 2 L 2 dimer, SH 3. Binding, Quantitative Exchange NMR-Based Ana., 1 fibril formation, Huntingtin Aggregation Huntingtin p., 1 Q 7, thioflavin T fluorescence assay, P 2 L

Relation: https://figshare.com/articles/journal_contribution/Quantitative_Exchange_NMR-Based_Analysis_of_Huntingtin_SH3_Interactions_Suggests_an_Allosteric_Mechanism_of_Inhibition_of_Huntingtin_Aggregation/14798528

الاتاحة: https://doi.org/10.1021/jacs.1c04786.s001

المؤلفون: Alberto Ceccon, Vitali Tugarinov, G. Marius Clore

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Pharmacology, Computational Biology, Chemical Sciences not elsewhere classified, polyglutamine tract, 16- residue N-terminal amphiphilic, 1 Q 35, htt, intracellular proline-binding domain, P 2 L 2, PL, sub-millisecond time scale, SH 3 increases, unliganded P 2 dimer, Fyn SH 3, concentration-dependent exchange-in, NT, P 2 L 2 dimer, SH 3. Binding, Quantitative Exchange NMR-Based Ana, 1 fibril formation, Huntingtin Aggregation Huntingtin p, 1 Q 7, thioflavin T fluorescence assay, P 2 L

Relation: https://doi.org/10.1021/jacs.1c04786.s001

الاتاحة: https://doi.org/10.1021/jacs.1c04786.s001