المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Controls_for_confocal_imaging_of_HEK293_cells_and_outline_of_Nb2_selections_/14470492

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s002

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Initial_identification_and_quantification_of_SMO_phosphorylation_sites_via_untargeted_mass_spectrometry_/14470525

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s013

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Generation_of_cell_lines_containing_BRET_donor_at_endogenous_i_Smo_i_locus_and_studies_of_interactions_between_soluble_SMO_pCT_and_PKA-C_/14470501

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s005

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/SMO_expression_constructs_and_controls_for_CREB_reporter_based_PKA_activity_assay_/14470489

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s001

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Additional_controls_for_microscopy_experiments_/14470495

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s003

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Controls_for_SMO_PKA-C_BRET_studies_/14470498

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s004

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Controls_for_PKA-R_BRET_experiments_and_PKA-C_mutagenesis_experiments_/14470507

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s007

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Controls_for_SMO_PKA-C_crosslinking_studies_/14470504

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s006

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Controls_for_assays_to_look_at_SMO_activity-_and_GRK2_3-dependent_interactions_/14470510

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s008

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Ciliary_localization_studies_/14470519

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s011

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Full_sequence_alignments_and_quantification_info_for_MS_/14470513

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s009

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Controls_for_SMO_sequence_coverage_in_MS_experiments_/14470516

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s010

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Tests_of_statistical_significance_/14470522

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s012

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/journal_contribution/Raw_blots_and_gels_underlying_Figs_1C_3C_and_3E_6A_and_7C_and_S1D_S5C_S6C_S7B_and_S8D_/14470549

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s021

المؤلفون: Abdelaziz, Reham

المساهمون: Pardo, Luis A. Prof. Dr., Göpfert, Martin Prof. Dr., Neef, Andreas Dr.

مصطلحات موضوعية: Kv10.1, Gating, Intracellular domains, Biologie (PPN619462639)

Time: 570

Relation: http://creativecommons.org/licenses/by-nc-nd/4.0/; http://hdl.handle.net/21.11130/00-1735-0000-0008-59E1-6; http://dx.doi.org/10.53846/goediss-9034; urn:nbn:de:gbv:7-21.11130/00-1735-0000-0008-59E1-6-7

الاتاحة: http://hdl.handle.net/21.11130/00-1735-0000-0008-59E1-6
https://doi.org/10.53846/goediss-9034
https://nbn-resolving.org/urn:nbn:de:gbv:7-21.11130/00-1735-0000-0008-59E1-6-7

المؤلفون: Pierre-Jean Corringer, José L. Guzmán, Jorge Fuentealba, Tiare Silva-Grecchi, Carola Muñoz-Montesino, Patricio A. Castro, Gustavo Moraga-Cid, Luis G. Aguayo, Carlos F. Burgos, Cesar O. Lara, Gonzalo E. Yévenes

المساهمون: Universidad de Concepción - University of Concepcion [Chile], Récepteurs Canaux - Channel Receptors, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), This work was supported by FONDECYT 1160851 (to G.M.), NIH R01AA025718 (to L.G.A.), FONDECYT 1170252 (to G.E.Y.), FONDECYT 1161078 (to J.F.), FONDECYT 11160562 (to P.A.C.), and FONDECYT 1170853 (to L.G.). C.F.B. was supported by the FONDECYT Postdoctoral 3170108. C.O.L. and T.S.-G. were supported by CONICYT doctoral fellowships. The authors thank L.A., I.C.. and J.G. for their outstanding technical assistance.

المصدر: ACS Chemical Neuroscience
ACS Chemical Neuroscience, 2019, 10 (5), pp.2551-2559. ⟨10.1021/acschemneuro.9b00050⟩

مصطلحات موضوعية: Physiology, Cognitive Neuroscience, intracellular domains, GLIC, Allosteric regulation, Neurotransmission, positive allosteric modulators, Cyanobacteria, Biochemistry, Membrane Potentials, chimera, 03 medical and health sciences, pLGICs, Receptors, Glycine, 0302 clinical medicine, Allosteric Regulation, Humans, [CHIM]Chemical Sciences, Receptor, Glycine receptor, Cells, Cultured, Ion channel, 030304 developmental biology, 0303 health sciences, ligand-gated ion channel, Ethanol, Isoflurane, Chemistry, glycine receptors, Central Nervous System Depressants, Intracellular Membranes, Cell Biology, General Medicine, Hydrogen-Ion Concentration, Ligand-Gated Ion Channels, Transmembrane protein, Cell biology, PAMs, Ligand-gated ion channel, Extracellular Space, 030217 neurology & neurosurgery, glycine receptors GLIC pLGICs ligand-gated ion channel chimera PAMs positive allosteric modulators intracellular domains

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d977796f1c0970d342e6efe3c8f37a
https://hal-pasteur.archives-ouvertes.fr/pasteur-04093112

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/dataset/Data_underlying_Fig_2C_and_2E_/14470531

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s015

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/dataset/Data_underlying_Figs_1B_and_1D_and_S1C_and_S1E_S1G_/14470528

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s014

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/dataset/Data_underlying_Figs_4B_4F_and_S7A_and_S7C_/14470537

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s017

المؤلفون: Corvin D. Arveseth (10688311), John T. Happ (10688314), Danielle S. Hedeen (10688317), Ju-Fen Zhu (10688320), Jacob L. Capener (10688323), Dana Klatt Shaw (10688326), Ishan Deshpande (9943676), Jiahao Liang (8085302), Jiewei Xu (715341), Sara L. Stubben (10688329), Isaac B. Nelson (10688332), Madison F. Walker (10688335), Kouki Kawakami (10688338), Asuka Inoue (52011), Nevan J. Krogan (90155), David J. Grunwald (9997490), Ruth Hüttenhain (10688341), Aashish Manglik (1942735), Benjamin R. Myers (10688344)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Infectious Diseases, Biological Sciences not elsewhere classified, cascade drives, Smoothened transduces Hedgehog signals, organ development, SMO activates GLI, control expression, mechanism, subunit, SMO intracellular domains, activates glioma-associated, GLI transcription, membrane, activity-dependent sequestration, GPCR kinase, transcription factors, GRK, Hh signal transduction, pathway target genes, PKA-mediated inhibition, sequestering protein kinase

Relation: https://figshare.com/articles/dataset/Data_underlying_Figs_3A_3D_and_S4A_S4F_and_S5A_and_S5E_/14470534

الاتاحة: https://doi.org/10.1371/journal.pbio.3001191.s016