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1Academic Journal
المؤلفون: Hlaváč, Matúš, Kováčiková, Lucia, Prnová, Marta, Addová, Gabriela, Hanquet, Gilles, Štefek, Milan, Boháč, Andrej
المساهمون: Laboratoire d'innovation moléculaire et applications (LIMA), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
المصدر: ISSN: 0968-0896.
مصطلحات موضوعية: aldose reductase (ALR2), interactive pocket, N-benzyl(oxotriazinoindole) ALR2 inhibitors, desolvation penalty, [CHIM]Chemical Sciences, [SDV]Life Sciences [q-bio]
Relation: hal-03070904; https://hal.archives-ouvertes.fr/hal-03070904; https://hal.archives-ouvertes.fr/hal-03070904/document; https://hal.archives-ouvertes.fr/hal-03070904/file/01_Publication-STFK_LK.pdf
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المؤلفون: Gilles Hanquet, Gabriela Addová, Matúš Hlaváč, Marta Soltesova Prnova, Milan Stefek, Lucia Kovacikova, Andrej Boháč
المساهمون: Laboratoire d'innovation moléculaire et applications (LIMA), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Hanquet, Gilles
المصدر: Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2020
Bioorganic and Medicinal Chemistry, Elsevier, 2021, 29, pp.115885. ⟨10.1016/j.bmc.2020.115885⟩مصطلحات موضوعية: Male, Indoles, Stereochemistry, N-benzyl(oxotriazinoindole) ALR2 inhibitors, [SDV]Life Sciences [q-bio], Clinical Biochemistry, Pharmaceutical Science, 01 natural sciences, Biochemistry, chemistry.chemical_compound, Structure-Activity Relationship, desolvation penalty, Aldehyde Reductase, Drug Discovery, [CHIM] Chemical Sciences, Lens, Crystalline, Animals, [CHIM]Chemical Sciences, Desolvation, Enzyme Inhibitors, Rats, Wistar, Molecular Biology, ComputingMilieux_MISCELLANEOUS, chemistry.chemical_classification, Aldose reductase, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Triazines, aldose reductase (ALR2), Organic Chemistry, 0104 chemical sciences, Rats, [SDV] Life Sciences [q-bio], Molecular Docking Simulation, 010404 medicinal & biomolecular chemistry, Enzyme, chemistry, Molecular Medicine, interactive pocket, Selectivity, Lead compound
وصف الملف: application/pdf