المؤلفون: Haohui Guo (6516638), Dong Ding (112949), Limei Wang (77943), Jiangbo Yan (11846768), Long Ma (133810), Qunhua Jin (6516644)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Physiology, Immunology, Cancer, Hematology, Chemical Sciences not elsewhere classified, resistant acid phosphatase, first day postoperative, evaluated using cck, blood glucose levels, analyze microstructural changes, inhibits osteoclast activation, cell cytoplasmic 1, met without effect, met suppressed rankl, met reversed decreases, met inhibited rankl, rankl ), ampk, nf -&# 954, detected using tartrate, detected using immunohistochemistry, nuclear factor kappa, metformin attenuates osteoclast, fast green staining, div >< p, activated protein kinase, 4 weeks postoperatively

Relation: https://figshare.com/articles/journal_contribution/S1_Raw_images_-/17225309

الاتاحة: https://doi.org/10.1371/journal.pone.0261127.s001

المؤلفون: Haohui Guo (6516638), Dong Ding (112949), Limei Wang (77943), Jiangbo Yan (11846768), Long Ma (133810), Qunhua Jin (6516644)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Physiology, Immunology, Cancer, Hematology, Chemical Sciences not elsewhere classified, resistant acid phosphatase, first day postoperative, evaluated using cck, blood glucose levels, analyze microstructural changes, inhibits osteoclast activation, cell cytoplasmic 1, met without effect, met suppressed rankl, met reversed decreases, met inhibited rankl, rankl ), ampk, nf -&# 954, detected using tartrate, detected using immunohistochemistry, nuclear factor kappa, metformin attenuates osteoclast, fast green staining, div >< p, activated protein kinase, 4 weeks postoperatively

Relation: https://figshare.com/articles/figure/Isolation_and_culture_of_primary_BMMs_and_osteoclast_differentiation_identification_and_proliferation_/17225324

الاتاحة: https://doi.org/10.1371/journal.pone.0261127.g002

المؤلفون: Haohui Guo (6516638), Dong Ding (112949), Limei Wang (77943), Jiangbo Yan (11846768), Long Ma (133810), Qunhua Jin (6516644)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Physiology, Immunology, Cancer, Hematology, Chemical Sciences not elsewhere classified, resistant acid phosphatase, first day postoperative, evaluated using cck, blood glucose levels, analyze microstructural changes, inhibits osteoclast activation, cell cytoplasmic 1, met without effect, met suppressed rankl, met reversed decreases, met inhibited rankl, rankl ), ampk, nf -&# 954, detected using tartrate, detected using immunohistochemistry, nuclear factor kappa, metformin attenuates osteoclast, fast green staining, div >< p, activated protein kinase, 4 weeks postoperatively

Relation: https://figshare.com/articles/figure/Met_restrains_F-actin_rings_formation_and_bone_resorption_of_osteoclast_in_vitro_/17225339

الاتاحة: https://doi.org/10.1371/journal.pone.0261127.g004

المؤلفون: Haohui Guo (6516638), Dong Ding (112949), Limei Wang (77943), Jiangbo Yan (11846768), Long Ma (133810), Qunhua Jin (6516644)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Physiology, Immunology, Cancer, Hematology, Chemical Sciences not elsewhere classified, resistant acid phosphatase, first day postoperative, evaluated using cck, blood glucose levels, analyze microstructural changes, inhibits osteoclast activation, cell cytoplasmic 1, met without effect, met suppressed rankl, met reversed decreases, met inhibited rankl, rankl ), ampk, nf -&# 954, detected using tartrate, detected using immunohistochemistry, nuclear factor kappa, metformin attenuates osteoclast, fast green staining, div >< p, activated protein kinase, 4 weeks postoperatively

Relation: https://figshare.com/articles/figure/Met_inhibits_the_differentiation_of_BMMs_into_osteoclasts_i_in_vitro_i_/17225333

الاتاحة: https://doi.org/10.1371/journal.pone.0261127.g003

المؤلفون: Haohui Guo (6516638), Dong Ding (112949), Limei Wang (77943), Jiangbo Yan (11846768), Long Ma (133810), Qunhua Jin (6516644)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Physiology, Immunology, Cancer, Hematology, Chemical Sciences not elsewhere classified, resistant acid phosphatase, first day postoperative, evaluated using cck, blood glucose levels, analyze microstructural changes, inhibits osteoclast activation, cell cytoplasmic 1, met without effect, met suppressed rankl, met reversed decreases, met inhibited rankl, rankl ), ampk, nf -&# 954, detected using tartrate, detected using immunohistochemistry, nuclear factor kappa, metformin attenuates osteoclast, fast green staining, div >< p, activated protein kinase, 4 weeks postoperatively

Relation: https://figshare.com/articles/figure/Schematic_of_animal_experiment_design_/17225315

الاتاحة: https://doi.org/10.1371/journal.pone.0261127.g001

المؤلفون: Haohui Guo (6516638), Dong Ding (112949), Limei Wang (77943), Jiangbo Yan (11846768), Long Ma (133810), Qunhua Jin (6516644)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Physiology, Immunology, Cancer, Hematology, Chemical Sciences not elsewhere classified, resistant acid phosphatase, first day postoperative, evaluated using cck, blood glucose levels, analyze microstructural changes, inhibits osteoclast activation, cell cytoplasmic 1, met without effect, met suppressed rankl, met reversed decreases, met inhibited rankl, rankl ), ampk, nf -&# 954, detected using tartrate, detected using immunohistochemistry, nuclear factor kappa, metformin attenuates osteoclast, fast green staining, div >< p, activated protein kinase, 4 weeks postoperatively

Relation: https://figshare.com/articles/figure/Met_inhibits_RANKL-induced_AMPK_NF-_B_and_ERK_activation_during_osteoclastogenesis_/17225348

الاتاحة: https://doi.org/10.1371/journal.pone.0261127.g005

المؤلفون: Haohui Guo (6516638), Dong Ding (112949), Limei Wang (77943), Jiangbo Yan (11846768), Long Ma (133810), Qunhua Jin (6516644)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Physiology, Immunology, Cancer, Hematology, Chemical Sciences not elsewhere classified, resistant acid phosphatase, first day postoperative, evaluated using cck, blood glucose levels, analyze microstructural changes, inhibits osteoclast activation, cell cytoplasmic 1, met without effect, met suppressed rankl, met reversed decreases, met inhibited rankl, rankl ), ampk, nf -&# 954, detected using tartrate, detected using immunohistochemistry, nuclear factor kappa, metformin attenuates osteoclast, fast green staining, div >< p, activated protein kinase, 4 weeks postoperatively

Relation: https://figshare.com/articles/figure/Met_attenuates_bone_loss_during_the_early_stage_of_DMM-induced_OA_/17225354

الاتاحة: https://doi.org/10.1371/journal.pone.0261127.g006

المؤلفون: Haohui Guo (6516638), Dong Ding (112949), Limei Wang (77943), Jiangbo Yan (11846768), Long Ma (133810), Qunhua Jin (6516644)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Physiology, Immunology, Cancer, Hematology, Chemical Sciences not elsewhere classified, resistant acid phosphatase, first day postoperative, evaluated using cck, blood glucose levels, analyze microstructural changes, inhibits osteoclast activation, cell cytoplasmic 1, met without effect, met suppressed rankl, met reversed decreases, met inhibited rankl, rankl ), ampk, nf -&# 954, detected using tartrate, detected using immunohistochemistry, nuclear factor kappa, metformin attenuates osteoclast, fast green staining, div >< p, activated protein kinase, 4 weeks postoperatively

Relation: https://figshare.com/articles/figure/Met_suppresses_cartilage_degeneration_by_inhibiting_osteoclastogenesis_in_the_early_stage_of_DMM-induced_OA_/17225363

الاتاحة: https://doi.org/10.1371/journal.pone.0261127.g007

المؤلفون: Haohui Guo (6516638), Dong Ding (112949), Limei Wang (77943), Jiangbo Yan (11846768), Long Ma (133810), Qunhua Jin (6516644)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Physiology, Immunology, Cancer, Hematology, Chemical Sciences not elsewhere classified, resistant acid phosphatase, first day postoperative, evaluated using cck, blood glucose levels, analyze microstructural changes, inhibits osteoclast activation, cell cytoplasmic 1, met without effect, met suppressed rankl, met reversed decreases, met inhibited rankl, rankl ), ampk, nf -&# 954, detected using tartrate, detected using immunohistochemistry, nuclear factor kappa, metformin attenuates osteoclast, fast green staining, div >< p, activated protein kinase, 4 weeks postoperatively

Relation: https://figshare.com/articles/figure/Met_inhibits_RANKL_NF-_B_expression_and_promoted_p-AMPK_expression_in_the_early_stage_of_DMM-induced_OA_/17225372

الاتاحة: https://doi.org/10.1371/journal.pone.0261127.g008

المؤلفون: Haohui Guo (6516638), Dong Ding (112949), Limei Wang (77943), Jiangbo Yan (11846768), Long Ma (133810), Qunhua Jin (6516644)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Physiology, Immunology, Cancer, Hematology, Chemical Sciences not elsewhere classified, resistant acid phosphatase, first day postoperative, evaluated using cck, blood glucose levels, analyze microstructural changes, inhibits osteoclast activation, cell cytoplasmic 1, met without effect, met suppressed rankl, met reversed decreases, met inhibited rankl, rankl ), ampk, nf -&# 954, detected using tartrate, detected using immunohistochemistry, nuclear factor kappa, metformin attenuates osteoclast, fast green staining, div >< p, activated protein kinase, 4 weeks postoperatively

Relation: https://figshare.com/articles/figure/Proposed_mechanism_of_Met-induced_attenuation_of_OA_via_the_inhibition_of_osteoclast_formation_/17225381

الاتاحة: https://doi.org/10.1371/journal.pone.0261127.g009

المؤلفون: Haohui Guo (6516638), Dong Ding (112949), Limei Wang (77943), Jiangbo Yan (11846768), Long Ma (133810), Qunhua Jin (6516644)

مصطلحات موضوعية: Biochemistry, Cell Biology, Molecular Biology, Physiology, Immunology, Cancer, Hematology, Chemical Sciences not elsewhere classified, resistant acid phosphatase, first day postoperative, evaluated using cck, blood glucose levels, analyze microstructural changes, inhibits osteoclast activation, cell cytoplasmic 1, met without effect, met suppressed rankl, met reversed decreases, met inhibited rankl, rankl ), ampk, nf -&# 954, detected using tartrate, detected using immunohistochemistry, nuclear factor kappa, metformin attenuates osteoclast, fast green staining, div >< p, activated protein kinase, 4 weeks postoperatively

Relation: https://figshare.com/articles/dataset/Primer_sequences_for_reverse_transcription-quantitative_PCR_/17225387

الاتاحة: https://doi.org/10.1371/journal.pone.0261127.t001