المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/journal_contribution/Characterization_of_the_Het-F_and_KO-M_mice_/17015393

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s001

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/journal_contribution/Flow_cytometry_characterization_of_Het-F_and_KO-M_mice_/17015396

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s002

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/journal_contribution/Global_identification_and_quantification_of_H3K4me3_H3K4me_H3K27me3_and_H3K27ac_binding_profiles_at_promoter_and_enhancer-like_regions_in_WT-F_and_KO-F_mouse_models_/17015411

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s007

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/journal_contribution/The_inactivation_of_i_Kdm6a_i_in_mice_had_age-_and_gender-dependent_effects_on_primitive_hematopoietic_cell_populations_and_myeloid_progenitors_48_/17015399

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s003

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/journal_contribution/Characterization_of_18-month-old_i_Kdm6a_i_conditional_KO_x_i_Vav1_i_-Cre_mice_/17015408

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s006

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/journal_contribution/The_i_Kdm6a_i_-null_stroma_and_hematopoietic_compartment_did_not_show_sex_specific_differences_/17015405

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s005

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/journal_contribution/Distribution_of_genome-wide_ChIP-seq_templates_around_the_annotated_TSS_/17015414

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s008

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/journal_contribution/S1_Raw_images_-/17015432

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s014

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/journal_contribution/Additional_information_regarding_experimental_procedures_and_material_can_be_found_in_S1_Methods_file_/17015429

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s013

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/dataset/Promoter_list_of_differential_H3K4me3_modification_between_WT_and_KO_/17015420

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s010

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/dataset/Table_of_active_enhancers_of_differential_modification_between_Kdm6a-WT_and_KO_at_H3K4_and_H3K27_/17015423

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s011

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/dataset/Table_of_differentially_expressed_genes_between_WT_and_KO_for_bulk_bone_marrow_progenitors_GMPs_PMNs_monocytes_and_macrophages_/17015426

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s012

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/dataset/List_of_antibodies_used_for_flow_cytometry_with_appropriate_catalog_numbers_/17015417

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.s009

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/figure/The_inactivation_of_i_Kdm6a_i_in_mice_had_age-_and_gender-dependent_effects_on_normal_hematopoiesis_/17015435

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.g001

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/figure/Characterization_of_hematopoietic_stem_and_progenitor_cells_from_BM_of_young_and_aged_KO-F_mice_vs_/17015441

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.g003

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/figure/The_loss_of_i_Kdm6a_i_alters_gene_expression_in_normal_hematopoiesis_/17015450

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.g006

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/figure/_i_Kdm6a_i_conditional_KO_mice_have_decreased_repopulating_potential_in_serial_competitive_transplantation_assays_/17015444

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.g004

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/figure/The_i_Kdm6a_i_-null_stroma_promotes_the_expression_of_i_Kdm6a-_i_null_hematopoietic_stem_and_progenitor_cells_/17015447

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.g005

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/figure/The_loss_of_i_Kdm6a_i_alters_gene_expression_in_early_stem_progenitor_cells_and_mature_myeloid_cells_/17015453

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.g007

المؤلفون: Ling Tian (107492), Monique Chavez (11707313), Gue Su Chang (11707316), Nichole M. Helton (11707319), Casey D. S. Katerndahl (11707322), Christopher A. Miller (10677605), Lukas D. Wartman (11707325)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Developmental Biology, Cancer, Hematology, Biological Sciences not elsewhere classified, zheng et al, inactivation may contribute, human aml samples, develop overt leukemia, allele inactivation initiated, 2 – 15, >< sup ><, seq studies showed, histone h3k27me3 demethylase, dependent myelodysplastic syndrome, >- ko mice, myelodysplastic syndrome, dependent expansion, >, >- wt, >- knockout, >- cre, yet clear, x chromosome, vav1 <, uty <, utx <

Relation: https://figshare.com/articles/figure/_i_Kdm6a_i_conditional_KO_induced_aberrant_myeloid_self-renewal_/17015438

الاتاحة: https://doi.org/10.1371/journal.pone.0255706.g002