المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/journal_contribution/S1_Materials_and_methods_-/16693745

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.s001

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/journal_contribution/S1_Results_-/16693748

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.s002

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/journal_contribution/Mutant_clonal_lines_screening_by_T7_endonuclease_I_assay_and_restriction_enzyme_digestions_/16693754

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.s004

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/journal_contribution/Screening_of_hFOB_transfected_with_the_pSpCas9_BB_-2A-GFP_and_pSpCas9_BB_-2A-GFP-gRNA-2_vectors_/16693751

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.s003

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/journal_contribution/Original_uncropped_scans_of_the_western_blots_shown_in_Fig_i_1B_i_and_Fig_i_3_i_C_/16693757

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.s005

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/journal_contribution/Ca_sup_2_sup_mobilization_from_ER_/16693760

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.s006

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/journal_contribution/Validation_of_further_i_TMEM38B_i_KO_hFOBs_/16693763

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.s007

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/journal_contribution/Expression_of_osteoblast_markers_and_osteoblast_proliferation_upon_inhibition_of_Ca_sup_2_sup_flux_by_2-APB_/16693766

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.s008

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/journal_contribution/Enzyme_digestion_for_clones_transfected_with_gRNA2_/16693769

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.s009

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/journal_contribution/Enzyme_digestion_for_clones_transfected_with_both_gRNA2_and_gRNA3_2_/16693775

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.s011

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/journal_contribution/S1_Raw_images_-/16693778

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.s012

مصطلحات موضوعية: hazardous occupation employment, biomarker of cytogenetic damages, уровень психофизиологической адаптации, cytogenetic monitoring, accumulation index of cytogenetic damages, цитогенетические нарушения, индекс пролиферации, vibraimage technology, буккальный микроядерный цитомный тест, цитогенетический мониторинг, biomarker of impaired proliferation, apoptotic index, апоптотический индекс, Донозологическая диагностика, Prenosological diagnostics, тех- нология виброизображения, psychophysiological adaptation level, индекс накопления цитогенетических нарушений, buccal micronucleus cytome assay, работники опасных производств

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::24509ea5e4d26d3f496103f424c44712

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/figure/OI_type_XIV_i_in_vitro_i_model_generation_and_western_blot_validation_/16693781

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.g001

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/figure/Expression_analysis_of_osteoblastogenic_markers_and_of_the_RANKL_OPG_ratio_/16693787

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.g003

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/figure/Intracellular_Ca_sup_2_sup_concentration_ER_calcium_flux_and_collagen_analysis_/16693784

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.g002

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/figure/Cell_proliferation_collagen_secretion_and_matrix_mineralization_analysis_/16693790

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.g004

المؤلفون: Laura Leoni (11495393), Francesca Tonelli (11495396), Roberta Besio (389022), Roberta Gioia (389023), Francesco Moccia (133351), Antonio Rossi (184985), Antonella Forlino (389028)

مصطلحات موضوعية: Microbiology, Genetics, Molecular Biology, Biological Sciences not elsewhere classified, technique widely applicable, patients ’ osteoblasts, patients ’ cells, fully take advantage, div >< p, ko clones unveiled, vivo <, vitro <, variable degree, use make, ubiquitously present, type xiv, tmem38b <, three grnas, severity associated, powerful technology, osteogenesis imperfecta, limited cost, largely unknown, impaired secretion, impaired proliferation, heritable disorders, endoplasmic reticulum

Relation: https://figshare.com/articles/dataset/Mutations_identified_in_gRNA-2_and_gRNA-3_2_transfected_clones_/16693793

الاتاحة: https://doi.org/10.1371/journal.pone.0257254.t001