المؤلفون: Aarón Otero, Sara Becerril, Marina Martín, Javier A. Cienfuegos, Víctor Valentí, Rafael Moncada, Victoria Catalán, Javier Gómez-Ambrosi, María A. Burrell, Gema Frühbeck, Amaia Rodríguez

المصدر: Frontiers in Endocrinology, Vol 14 (2023)

مصطلحات موضوعية: uroguanylin, guanylin, guanylate cyclase 2C, β-cell function, lipogenesis, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2023.1185456/full; https://doaj.org/toc/1664-2392

URL الوصول: https://doaj.org/article/a67e37be52534e13972180aa549273c8

المؤلفون: Nobuhiko Ebisutani, Hirokazu Fukui, Heihachiro Nishimura, Takashi Nakanishi, Kenki Morimoto, Shiho Itou, Ayumi Nakamura, Mizuki Masutani, Mika Hori, Toshihiko Tomita, Tadayuki Oshima, Emiko Kasahara, Atsuo Sekiyama, Hiroto Miwa

المصدر: Frontiers in Physiology, Vol 11 (2020)

مصطلحات موضوعية: social defeat stress, depression, constipation, guanylin, uroguanylin, guanylate cyclase 2C, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2020.599582/full; https://doaj.org/toc/1664-042X

URL الوصول: https://doaj.org/article/4edf0aa2c65c498fb9ba4d69e61b7bcf

المؤلفون: Aarón Otero, Sara Becerril, Marina Martín, Javier A. Cienfuegos, Víctor Valentí, Rafael Moncada, Victoria Catalán, Javier Gómez-Ambrosi, María A. Burrell, Gema Frühbeck, Amaia Rodríguez

مصطلحات موضوعية: Endocrinology, Reproduction, Cell Metabolism, uroguanylin, guanylin, guanylate cyclase 2C, β-cell function, lipogenesis

Relation: https://figshare.com/articles/dataset/DataSheet_1_Effect_of_guanylin_peptides_on_pancreas_steatosis_and_function_in_experimental_diet-induced_obesity_and_after_bariatric_surgery_docx/22917749

الاتاحة: https://doi.org/10.3389/fendo.2023.1185456.s001
https://figshare.com/articles/dataset/DataSheet_1_Effect_of_guanylin_peptides_on_pancreas_steatosis_and_function_in_experimental_diet-induced_obesity_and_after_bariatric_surgery_docx/22917749

المؤلفون: Scott A. Waldman, Adam E. Snook, Ariana A Entezari

المصدر: Expert Opin Ther Targets

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Clinical Biochemistry, Receptors, Enterotoxin, Article, 03 medical and health sciences, 0302 clinical medicine, Gastrointestinal Agents, Drug Discovery, medicine, Animals, Humans, Molecular Targeted Therapy, Guanylyl Cyclase 2C, Gastrointestinal Neoplasms, Pharmacology, business.industry, Immunotherapy, Guanylate cyclase 2C, Signaling system, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, Molecular Medicine, business, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54672255ddf4af4589c087ad64f6def4
https://doi.org/10.1080/14728222.2021.1937124

المؤلفون: Bradley Stringer, Kurt Eng, Katharine C. Lai, Mark G. Qian, Jennifer Fretland, Melissa Gallery, Robbie Robertson, Melissa Saylor Landen, Cindy Q. Xia, Adnan O. Abu-Yousif, O. Petter Veiby, Afrand Kamali, Maria Borland, Secil Koseoglu, Bret Bannerman, Andy Z. X. Zhu, Michelle L. Ganno, Thomas A. Keating, Michael D. Smith, Donna Cvet, Jayaprakasam Bolleddula

المصدر: Molecular Cancer Therapeutics. 19:2079-2088

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Biodistribution, Immunoconjugates, medicine.drug_class, Mice, Nude, Monoclonal antibody, Mice, 03 medical and health sciences, 0302 clinical medicine, In vivo, medicine, Animals, Humans, Cytotoxic T cell, Tissue Distribution, Tight junction, Chemistry, Guanylate cyclase 2C, Xenograft Model Antitumor Assays, In vitro, HEK293 Cells, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Female, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36fad95085a4edda953eff31247a4c7
https://doi.org/10.1158/1535-7163.mct-19-1102

المؤلفون: Sakineh Seyed-Mohammadi, Azar Dokht Khosravi, Ali Teimoori

المصدر: Reviews in Medical Microbiology. 32:114-123

مصطلحات موضوعية: Microbiology (medical), Lactobacillus casei, biology, Colorectal cancer, Dendritic cell, Guanylate cyclase 2C, Binding peptide, medicine.disease, biology.organism_classification, Molecular biology, System a, law.invention, law, Recombinant DNA, medicine, CRISPR

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ad68d05bb332953c1a062e7cc20327f2
https://doi.org/10.1097/mrm.0000000000000243

المؤلفون: Sandhya S. Visweswariah, Avipsa Bose, Sanghita Banerjee

المصدر: IUBMB Life

مصطلحات موضوعية: 0301 basic medicine, Guanylin, Clinical Biochemistry, Receptors, Enterotoxin, Endogeny, Disease, Enterotoxin, Biology, Biochemistry, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Allosteric Regulation, Protein Domains, Genetics, Humans, Receptor, Molecular Biology, Cell Biology, Guanylate cyclase 2C, Intestinal epithelium, Cell biology, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Mutation, Meconium Ileus, Signal Transduction, Uroguanylin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6464b539158a941d18b854074f8171ba
https://doi.org/10.1002/iub.2283

المؤلفون: Kelly F. Meijsen, Hugo R. de Jonge, Antje Ballauff, Anke H M van Vugt, Roderick H. J. Houwen, Manuel B Bryant, Thomas Müller, Sabine Middendorp, Tanja Restin, Marcel J. C. Bijvelds, Andreas R. Janecke, Bart G. P. Koot

المساهمون: Gastroenterology & Hepatology, Paediatric Gastroenterology, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, ARD - Amsterdam Reproduction and Development, University of Zurich, Pediatrics

المصدر: Clinical and Translational Gastroenterology, 12(11):e00427. Nature Publishing Group
van Vugt, A H M, Bijvelds, M J C, de Jonge, H R, Meijsen, K F, Restin, T, Bryant, M B, Ballauff, A, Koot, B, Müller, T, Houwen, R H J, Janecke, A R & Middendorp, S 2021, ' A Potential Treatment of Congenital Sodium Diarrhea in Patients With Activating GUCY2C Mutations ', CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, vol. 12, no. 11, pp. e00427 . https://doi.org/10.14309/ctg.0000000000000427
Clinical and translational gastroenterology, 12(11). Nature Publishing Group
Clinical and Translational Gastroenterology
CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 12(11). Nature Publishing Group

مصطلحات موضوعية: Diarrhea, medicine.medical_specialty, Receptors, Enterotoxin, Stimulation, 610 Medicine & health, Enterotoxin, Heterocyclic Compounds, 4 or More Rings, Cystic fibrosis, Basal (phylogenetics), chemistry.chemical_compound, SDG 3 - Good Health and Well-being, Internal medicine, medicine, Organoid, Humans, Abnormalities, Multiple, Functional GI Disorders, Cyclic GMP, Cyclic guanosine monophosphate, business.industry, Brief Report, Gastroenterology, Guanylate cyclase 2C, medicine.disease, 10027 Clinic for Neonatology, Endocrinology, chemistry, Gain of Function Mutation, business, Metabolism, Inborn Errors, Intracellular

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d3192ebcfb634acea304772d3b318e
https://pure.eur.nl/en/publications/476a3967-0cd2-4270-92cc-95c7bcb17260

المؤلفون: David Kastenberg, Ryan McMurray, Christopher H. Henry, Walter K. Kraft, Paul J. Limburg, David S. Weinberg, Leo Katz, Scott A. Waldman, Nathan R. Foster, Gary Della'Zanna, Angela Pallotto, Stephanie Moleski

المصدر: Cancer Biol Ther

مصطلحات موضوعية: Agonist, Cancer Research, medicine.drug_class, Guanylin, Receptors, Enterotoxin, Pharmacology, chemistry.chemical_compound, Double-Blind Method, medicine, Humans, Large intestine, Receptor, Linaclotide, Cyclic GMP, business.industry, Guanylate cyclase 2C, Healthy Volunteers, medicine.anatomical_structure, Oncology, chemistry, Receptors, Guanylate Cyclase-Coupled, Molecular Medicine, business, Colorectal Neoplasms, Peptides, Uroguanylin, Hormone, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce382e07a7d876ae08d5c499b9b7fa85
https://europepmc.org/articles/PMC8726613/

المؤلفون: David S. Reasner, Ramesh Boinpally, Benjamin D. Gold, Stavra A. Xanthakos, Hanna Kwak, Madhuja Mallick, Christopher R. O'Dea, Mitchell B. Cohen, Wilmin Bartolini, Taryn Weissman, Pei Ge, Nicholas CaJacob

المصدر: Journal of pediatric gastroenterology and nutrition. 73(6)

مصطلحات موضوعية: medicine.medical_specialty, Adolescent, Colon, Duodenum, Mrna expression, Colonoscopy, Gastroenterology, Internal medicine, medicine, Humans, RNA, Messenger, Intestinal Mucosa, Receptor, Child, Irritable bowel syndrome, Chronic constipation, medicine.diagnostic_test, business.industry, Infant, Guanylate cyclase 2C, medicine.disease, Endoscopy, medicine.anatomical_structure, Guanylate Cyclase, Child, Preschool, Pediatrics, Perinatology and Child Health, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682d005eb569c235939a3006c7dfa6bc
https://pubmed.ncbi.nlm.nih.gov/34508047

المؤلفون: Idrees A Shah, Shashi Kiran, Mudasir M. Reshi, Anaxee Barman, Swarna Srinivas, Sanghita Banerjee, Vishwas Mishra, Pooja Chaukimath, Sandhya S. Visweswariah, Avipsa Bose

المصدر: The Journal of Experimental Medicine

مصطلحات موضوعية: Guanylin, Immunology, Mutant, Innate Immunity and Inflammation, Guanylate cyclase 2C, Biology, medicine.disease, Inflammatory bowel disease, Molecular biology, Article, chemistry.chemical_compound, chemistry, medicine, Immunology and Allergy, Colitis, GUCY2C Gene, Dysbiosis, Uroguanylin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60bb4b4d19d37ae75754d2000daf962b
http://europepmc.org/articles/PMC8480670

المؤلفون: Erik S. Blomain, Jeffrey A. Rappaport, Scott A. Waldman, Amanda M. Pattison, Adam E. Snook, Babar Bashir, Ellen M. Caparosa, Jonathan Stem

المصدر: Cancer Biology & Therapy
article-version (VoR) Version of Record

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, β catenin tcf signaling, Colorectal cancer, Guanylin, Adenomatous Polyposis Coli Protein, Receptors, Enterotoxin, colorectal cancer, medicine.disease_cause, law.invention, Gastrointestinal Hormones, Mice, 03 medical and health sciences, 0302 clinical medicine, Transcription (biology), law, Cell Line, Tumor, Databases, Genetic, Paracrine Communication, medicine, Transcriptional regulation, chemoprevention, Animals, Humans, transcriptional regulation, Genes, Tumor Suppressor, Intestinal Mucosa, guanylyl cyclase C, Natriuretic Peptides, beta Catenin, Mice, Knockout, Pharmacology, Chemistry, GUCA2A, Guanylate cyclase 2C, medicine.disease, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Molecular Medicine, Suppressor, Colorectal Neoplasms, TCF Transcription Factors, Carcinogenesis, Research Article, Research Paper, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382d7faa43164968ecd08d135d597728
https://doi.org/10.1080/15384047.2020.1721262

المؤلفون: Megan Weindorfer, Amanda Lisby, Babar Bashir, Sanjna Shelukar, Adam E. Snook, John C. Flickinger, Scott A. Waldman, Madison Crutcher

المصدر: Expert Rev Precis Med Drug Dev

مصطلحات موضوعية: Pharmacology, Oncology, medicine.medical_specialty, Colorectal cancer, business.industry, Disease, Guanylate cyclase 2C, medicine.disease, digestive system diseases, Article, Internal medicine, Drug Discovery, Genetics, medicine, Molecular Medicine, CAR T-cell therapy, Biomarker (medicine), Cancer vaccine, Stage (cooking), Antibody therapy, business, neoplasms

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ca78fc7373f31ee62a6ffe4aebcec1
https://pubmed.ncbi.nlm.nih.gov/34027103

المؤلفون: Joshua R Barton, John C. Flickinger, Jeffrey A. Rappaport, Trevor R. Baybutt, Amanda M. Pattison, Adam E. Snook, Scott A. Waldman

المصدر: Biomark Med

مصطلحات موضوعية: 0301 basic medicine, Colorectal cancer, medicine.medical_treatment, Clinical Biochemistry, Receptors, Enterotoxin, Context (language use), Review, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, Humans, Gastrointestinal cancer, Molecular Targeted Therapy, Gastrointestinal Neoplasms, business.industry, Stomach, Biochemistry (medical), Cancer, Immunotherapy, Guanylate cyclase 2C, medicine.disease, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Cancer research, Pancreas, business, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8cb9a2c879e8667480f935b2f17f6b
https://europepmc.org/articles/PMC8293028/

المؤلفون: Kenki Morimoto, Mizuki Masutani, Mika Hori, Emiko Kasahara, Atsuo Sekiyama, Tadayuki Oshima, Hirokazu Fukui, Takashi Nakanishi, Shiho Itou, Nobuhiko Ebisutani, Heihachiro Nishimura, Hiroto Miwa, Toshihiko Tomita, Ayumi Nakamura

المصدر: Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Physiology, Guanylin, Stimulation, guanylin, lcsh:Physiology, Social defeat, 03 medical and health sciences, chemistry.chemical_compound, social defeat stress, 0302 clinical medicine, Internal medicine, Physiology (medical), Medicine, stool, Dexamethasone, Original Research, lcsh:QP1-981, business.industry, uroguanylin, constipation, Pathophysiology, 030104 developmental biology, Endocrinology, chemistry, guanylate cyclase 2C, depression, Immunohistochemistry, glucocorticoid, business, 030217 neurology & neurosurgery, Glucocorticoid, medicine.drug, Uroguanylin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b166b966a5bfc6a7a61091d44a6c68e
https://www.frontiersin.org/articles/10.3389/fphys.2020.599582/full

المؤلفون: Trevor R. Baybutt, Adam E. Snook, Megan Weindorfer, Amanda Lisby, Scott A. Waldman, Alicja Zalewski, Robert D Carlson

المصدر: Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)

مصطلحات موضوعية: Colorectal cancer, business.industry, Cancer, Guanylate cyclase 2C, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282, Chimeric antigen receptor, Cell therapy, Antigen, Cancer research, medicine, Adenocarcinoma, Enterocyte differentiation, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6688d845448cedbc78301ea678ae2199
https://doaj.org/article/74cc85a886b442009f650fe93afeb8a9

المؤلفون: Scott A. Waldman, Jeffrey A. Rappaport

المصدر: Expert Rev Clin Pharmacol

مصطلحات موضوعية: Colorectal cancer, medicine.medical_treatment, Receptors, Enterotoxin, Context (language use), medicine.disease_cause, 030226 pharmacology & pharmacy, Chemoprevention, Article, 03 medical and health sciences, 0302 clinical medicine, Medicine, Animals, Humans, Pharmacology (medical), Molecular Targeted Therapy, General Pharmacology, Toxicology and Pharmaceutics, Neoplasm Staging, business.industry, Guanylyl Cyclase C Agonists, General Medicine, Immunotherapy, Guanylate cyclase 2C, medicine.disease, Chimeric antigen receptor, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Plecanatide, business, Carcinogenesis, Colorectal Neoplasms, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf395f7c7edd6a50cb3520b605725a31
https://pubmed.ncbi.nlm.nih.gov/32945718

المؤلفون: Huyuan Yang, Toshihiko Doi, Hui Wang, Chia-Chi Lin, Hadi Danaee, Takayuki Asato, Thea Kalebic, Adedigbo Fasanmade, Toshimi Takano, Yung-Jue Bang

المصدر: Cancer Research and Treatment : Official Journal of Korean Cancer Association

مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, medicine.medical_specialty, Nausea, Receptors, Enterotoxin, Neutropenia, Antibodies, Monoclonal, Humanized, Gastroenterology, 03 medical and health sciences, Gastrointestinal cancer, 0302 clinical medicine, Pharmacokinetics, Internal medicine, Ascites, Carcinoma, medicine, Humans, Adverse effect, Aged, Gastrointestinal Neoplasms, business.industry, Stomach, Antibodies, Monoclonal, Guanylate cyclase 2C, Middle Aged, medicine.disease, Clinical trial, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Original Article, Female, medicine.symptom, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf000fc1285a6cb2a2628b4cfb5c778
http://europepmc.org/articles/PMC5912138

المؤلفون: Yu-ping Zhu, Hai-Xing Ju, Dechuan Li, Guoping Cheng, Meucci Stefano, Ulrich Keilholz, Yong Liu, Jun Qian

المصدر: Oncotarget

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Pathology, medicine.medical_specialty, Colorectal cancer, overall survival, Rectum, Metastasis, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Biomarkers, Tumor, medicine, Humans, Stage (cooking), guanylyl cyclase C, rectal cancer, disease free survival, Survival rate, Aged, Aged, 80 and over, tumor metastasis, Rectal Neoplasms, business.industry, Cancer, Guanylate cyclase 2C, Middle Aged, Neoplastic Cells, Circulating, Prognosis, medicine.disease, Survival Rate, 030104 developmental biology, medicine.anatomical_structure, Case-Control Studies, Lymphatic Metastasis, 030220 oncology & carcinogenesis, Biomarker (medicine), Female, business, Receptors, Atrial Natriuretic Factor, Follow-Up Studies, Research Paper

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3654b100afd0055c476d3961bd127019
https://doi.org/10.18632/oncotarget.16406

المؤلفون: Sayaka Akieda-Asai, Hao Ma, Yukari Date

المصدر: American journal of physiology. Cell physiology. 317(6)

مصطلحات موضوعية: 0301 basic medicine, Lipopolysaccharides, Physiology, THP-1 Cells, Guanylin, Palmitic Acid, Cell Line, Palmitic acid, Gastrointestinal Hormones, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Genes, Reporter, Gene expression, Macrophages, Alveolar, Macrophage, Animals, Humans, Receptor, Luciferases, Natriuretic Peptides, Cyclic GMP, Toll-like receptor, Chemistry, NF-kappa B, NF-κB, Cell Biology, Guanylate cyclase 2C, Cell biology, Rats, Toll-Like Receptor 4, 030104 developmental biology, RAW 264.7 Cells, Gene Expression Regulation, Receptors, Guanylate Cyclase-Coupled, 030217 neurology & neurosurgery, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792be61ab66479ab504bbfd6da05f53c
https://pubmed.ncbi.nlm.nih.gov/31553648